A national team of scientists is investigating fertility preservation for women with cancer through the $20 million program. MU researcher John Critser will receive funding to study cryopreservation methods of human eggs, aiming to improve efficiency and challenges in the process.
A study published in Journal of Evolutionary Biology found that penduline tit parents frequently abandon 1 in 3 clutches of eggs to pursue new mates. This unique breeding strategy allows for improved reproductive success but also poses risks for the young.
Scientists successfully extracted and froze eggs from ovarian tissue of girls as young as 5 years old, a breakthrough in preserving fertility in young cancer patients. The study found an average of 8.5 eggs per patient, with a 32% success rate in maturing the eggs in vitro.
Researchers are conducting phase I trials comparing slow-freezing techniques to a rapid method of cryopreservation that transforms tissues into glass-like structures. The goal is to make human eggs, ovarian tissue, blood vessels, and whole organs available when needed.
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A study by USF researchers debunks the theory that older women can generate new eggs, challenging a controversial finding made by Harvard scientist Jonathan Tilly. The researchers found no evidence of egg stem cells in ovarian cells biopsied from 12 women between 28 and 53 years old.
Two studies found that eating eggs for breakfast can lead to significant weight loss and improved energy levels. Additionally, eggs are an excellent source of choline, essential for brain function and development, and may help close the nutrient consumption gap among pregnant women and older adults.
A new experimental flu vaccine produced using insect cells has shown promising results in early testing, demonstrating safety and immunogenic response in healthy adults. The vaccine, made using recombinant DNA techniques, offers a potential alternative to traditional egg-based vaccines.
Researchers found that when cowbird eggs were removed from warbler nests, the nests were ransacked 56% of the time, but only 6% when the eggs were accepted. This suggests that cowbirds engage in 'mafia' behavior to encourage hosts to raise their young.
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The Rong Li lab team has identified a crucial pathway controlling asymmetric meiotic cell division in mouse oocytes, allowing for genomic reduction while maintaining essential building blocks. This finding provides insights into the molecular signals driving egg maturation and its significance for reproductive health.
A pre-hatching prototype vaccine virus providing immunity against infectious bronchitis virus (IBV) has been developed by scientists at the Institute for Animal Health and Intervet UK. The vaccine can be delivered to chicks still in their egg using robotic 'vaccinators' and has shown protection rates of up to 100 percent.
Researchers explore using tardigrade-produced trehalose to preserve human eggs, offering a potential solution to successful embryo cryopreservation. The method has shown promising results in mouse eggs, and further research aims to apply it to human eggs and endangered species.
Researchers have created mouse embryonic stem cells that can be transplanted without rejection due to genetic matching with the recipient's immune system. The cells were generated from unfertilized eggs through a series of chemical treatments and identified using genetic typing.
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Researchers found that spotted salamanders, wood frogs, and American toads employ various defense strategies to avoid water mold infections, including protective jelly layers and early hatching. These mechanisms help reduce mortality rates and increase survival chances for the amphibian species.
Researchers identify 5,400 active genes in mouse eggs, including unique ones specific to egg cells, and find evidence of rapid change in critical mammalian genes. This study provides new information on the transition from unfertilized egg to fertilized embryo.
Researchers found that bird moms alter the birth order of eggs to shield sons from mites, speeding up their growth and survival. This strategy allows both males and females to thrive despite increased mortality risk from parasites.
Researchers at Michigan State University have identified 5,331 unique genes in the human egg, which may hold the key to understanding fertility issues and developing new stem cell therapies. The discovery could also pave the way for the creation of healthy stem cells without the need for fertilized embryos.
Researchers at FSU have identified a key component in cell polarity formation in fruit fly eggs, which also play a role in human diseases like muscular dystrophy and some cancers. The study's findings could lead to a better understanding of how cell-to-cell communication occurs in other types of cells and organisms.
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Researchers from Northwestern University have developed a three-dimensional culture system to preserve immature eggs for female fertility preservation. The technology, which mimics the ovary environment, has successfully led to the live birth of healthy mice from in vitro grown follicles.
Researchers find that female mice can maintain a steady number of eggs throughout adulthood, contradicting the long-held assumption that eggs decline with age. The study's findings suggest potential directions for ovarian stem cell research and fertility treatments.
A new egg freezing technique called Cryotop method has been developed, achieving a more than 90% survival rate for frozen-thawed eggs and a high pregnancy rate of nearly 42%. The process involves rapid freezing in a tiny amount of special vitrification solution, preventing ice crystals from forming damage to the egg. This technology op...
Egg donation for stem cell research is a contentious issue, with concerns over informed consent, health risks, and distributive justice. Researchers have developed guidelines to balance bioethical principles and reduce risks for donors, exploring alternative sources of eggs and incentivizing participation.
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Researchers found that the Wnt4 and Fgf9 genes are initially balanced before Sry triggers a cascade leading to testis formation. In contrast, an imbalance between these signals determines sex determination in vertebrates.
Researchers discover unique egg-forming structure in Amborella, potentially linking flowering plants to extinct gymnosperm ancestors. The novel embryo sac configuration could be a relic of intense evolutionary activity, shedding light on the origin and evolution of flowering plants.
Researchers at UCSC discover that Hymenopteran insects create new centrosomes in unfertilized eggs using accessory nuclei. This process allows for the development of haploid males, which have half the number of chromosomes as females. The study sheds light on basic cell biology and the evolution of these social insects.
Researchers found high levels of selenium in contaminated toads and their offspring, leading to developmental abnormalities such as structural malformations and abnormal swimming. The study highlights the importance of maternal transfer in contaminant exposure for amphibians.
Biologists at Brown University and the University of California–Berkeley have discovered a critical role for two proteins – TAF4b and c-Jun – in the growth and nurturing of granulosa cells that surround eggs. The finding provides important new information about fertility and may lead to better in-vitro fertilization therapies.
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Scientists develop a new sonar method to detect squid egg clusters, allowing for efficient mapping and estimation of squid populations. This technique has immediate potential to provide resource managers with sound scientific information to sustain the fishery and protect the species' genetic diversity.
Researchers found that exposing egg cells to nitric oxide can slow the hardening of their outer shells and increase the release of cortical granules, potentially extending their fertilizable time window. This could lead to improved fertility in women and reduce the risk of chromosomal abnormalities during early embryonic development.
Researchers have successfully produced human monoclonal antibodies in chicken eggs, demonstrating enhanced cell killing activity compared to conventionally produced antibodies. The new technology has the potential to drive down drug manufacturing costs and make medicines more affordable.
Researchers have discovered that microRNAs are involved in the process of oogenesis, a complex regulatory mechanism controlling protein abundance. The findings suggest that miRNA dysfunction may contribute to certain forms of infertility.
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A study by Christine Gieseke and Prue Talbot found that cigarette smoke significantly reduces the transport of hamster eggs through the oviduct. The researchers exposed cumulus-coated eggs to six types of cigarette smoke, resulting in a 40-55% increase in adhesion to the infundibulum and a 20-35% decrease in egg transportation rates.
Scientists have successfully developed ovarian structures containing eggs from embryonic stem cells, a breakthrough that could provide new hope for infertile couples. The method uses growth factors derived from testicular cells to induce the development of female reproductive cells.
Scientists at the University of Manchester studied the mating behaviour of dusky roaches to understand the mechanisms behind age-related decline in female fertility. The research suggests a natural biochemical reaction is to blame, where perfectly healthy eggs begin to die due to delayed reproduction.
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Researchers found that disabling a specific gene in fruit flies causes premature maturation, leading to small and misshapen adults. This study provides insight into the genetic mechanisms controlling human development from childhood to adolescence.
Researchers at U-M have identified a method that produces viable eggs when thawed, allowing cancer patients to preserve fertility. The vitrification technique enables 98% survival of eggs after thawing, compared to traditional slow-freeze techniques.
Stem cells can be made specific to patients regardless of age or sex, showing promise for treating devastating diseases and injuries. The research yields patient-specific cellular models of human disease, paving the way for more precise study and potential cure.
Women donating eggs for stem cell research face unique risks and lack adequate protections. Stanford bioethicists advocate for a new category of research subjects and set of guidelines to ensure informed consent. The proposed changes aim to promote ethical egg donation practices.
Researchers found that red-eyed tree frog embryos distinguish between snake-attack and rain-induced vibrations, hatching early in response to the former. The study suggests that temporal patterns of vibrations play a crucial role in triggering early hatching, allowing the embryos to avoid snake attacks.
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Researchers have successfully developed human eggs from ovarian surface cells (OSE cells) in a laboratory setting. This breakthrough has potential applications in human reproduction, including increased chances of conception for women with reduced fertility and premature menopause.
Researchers discovered a new species of coral-reef pygmy goby that lives for just 59 days, with daily mortality rates as high as 8%. The tiny fish lays only three clutches of eggs in its lifetime, contributing to the complex and hectic life cycle of reef fish.
Researchers found that the number of vertebrae in cloned carp-goldfish fish was determined by the goldfish's egg cytoplasm, not its genetic code. The study suggests a
The study explores how classical polyandry, a practice where multiple males mate with a single female, has evolved in different species. It reveals that this practice enhances female reproductive success and social stability through the provision of genetic diversity and protection from predators.
Researchers found a gene that produces peroxide to 'stitch' together proteins surrounding the egg, hardening it into a protective barrier. This process helps prevent polyspermy and protects fertilized eggs from damage.
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Researchers use nuclear transfer to add women's own mitochondria to eggs, preventing inherited diseases caused by mitochondrial mutations. The technique involves adding the woman's own mitochondria to her eggs, reducing controversy and potential health risks compared to using donor mitochondria.
Research suggests that retrotransposons, previously considered 'junk DNA', can initiate synchronous gene expression in mouse eggs and early embryos. This discovery may contribute to the reprogramming of the mammalian embryonic genome.
A new study reveals that cowbird chicks survive and even grow faster when raised in noisy nests with host siblings, rather than alone. By joining their nestmates in a chirping chorus, the cowbirds are able to monopolize food attempts from parents and reap the benefits of shared parental care.
Researchers created a mouse model with increased cAMP levels in eggs, leading to infertility. By blocking another protein, egg maturation was completed, revealing potential new contraceptive targets.
Researchers discovered that human stem cells can replenish muscle fibers in mice with Duchene muscular dystrophy, offering a potential treatment. In contrast, elevated cyclic AMP levels halted egg maturation in females, while HIV protease inhibitors impaired osteoclasts leading to bone loss.
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Researchers at Seoul National University successfully produced genetically identical stem cells through somatic cell nuclear transfer (SCNT). The breakthrough holds promise for treating a large number of currently untreatable conditions, including inherited diseases.
Egg freezing may provide an alternative for infertile couples trapped by Italian law, allowing them to have children. Researchers hope that this technique can limit the consequences of the law on infertile couples.
A new technique for preserving fertility in young women with cancer has been successfully used on eight female patients. The method involves removing immature eggs from the ovaries, maturing them through in-vitro maturation (IVM), and freezing them for later use.
Researchers say broad body of research shows UV-B radiation can cause severe damage to amphibian species from eggs to adults, including retinal damage and blindness. Amphibian declines are linked to multiple causes, but UV-B remains a significant concern.
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Researchers found that female penguins have significantly more mollusk shells in their stomachs than males before laying eggs, providing a slow-calcium release. The thick eggshells are crucial for protecting eggs from breakage and predation, particularly in large colonies.
Researchers at University of Pittsburgh successfully used suspension culture systems to promote follicular growth in rats and mice, showing promise for preserving ovarian fertility after cancer treatment. The study's findings suggest a promising step towards conserving fertility for cancer patients.
Researchers have developed versatile human embryonic stem cells capable of becoming any cell type, offering potential for transplantation medicine. The cells were created by transferring a somatic cell nucleus into an egg, reprogramming its genes to produce pluripotent stem cells.
Researchers discover transgenic mosquitoes are severely impaired in development and reproduction, laying fewer eggs and having lower egg-adult survivorship. This finding has major implications for the competitiveness of transgenic mosquitoes against non-engineered wild-types.
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Researchers at the University of Pennsylvania have discovered a critical regulatory role of protein CTCF in controlling gene imprinting in eggs. The study found that lower levels of CTCF resulted in higher DNA methylation and reduced fertility in female mice.
A study by the Lister Fertility Clinic in London found that women who participated in an egg-sharing program did not have a lower chance of getting pregnant or having a live birth compared to those who didn't participate. The researchers also found no evidence of increased risk of ovarian hyperstimulation syndrome among donors.
Marine biologists have discovered a unique undersea nursery off Northern California, where groups of fish and octopus brood their eggs. The discovery represents a new type of biological hot spot, with potential implications for conservation efforts.
Researchers isolated a honeybee gene called csd, revealing that female bees have two different versions of the gene that form an active protein triggering female development. This discovery explains how male and female bees develop from fertilized and unfertilized eggs, respectively.
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