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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

MU researchers to collaborate on $20 million project

A national team of scientists is investigating fertility preservation for women with cancer through the $20 million program. MU researcher John Critser will receive funding to study cryopreservation methods of human eggs, aiming to improve efficiency and challenges in the process.

Parents seeking sex abandon 1 in 3 offspring

A study published in Journal of Evolutionary Biology found that penduline tit parents frequently abandon 1 in 3 clutches of eggs to pursue new mates. This unique breeding strategy allows for improved reproductive success but also poses risks for the young.

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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

No evidence older women generate new eggs

A study by USF researchers debunks the theory that older women can generate new eggs, challenging a controversial finding made by Harvard scientist Jonathan Tilly. The researchers found no evidence of egg stem cells in ovarian cells biopsied from 12 women between 28 and 53 years old.

Eggs promote weight loss and help close nutrient consumption gap

Two studies found that eating eggs for breakfast can lead to significant weight loss and improved energy levels. Additionally, eggs are an excellent source of choline, essential for brain function and development, and may help close the nutrient consumption gap among pregnant women and older adults.

Experimental flu vaccine appears promising in early tests

A new experimental flu vaccine produced using insect cells has shown promising results in early testing, demonstrating safety and immunogenic response in healthy adults. The vaccine, made using recombinant DNA techniques, offers a potential alternative to traditional egg-based vaccines.

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Rong Li Lab demonstrates the process of mammalian egg maturation

The Rong Li lab team has identified a crucial pathway controlling asymmetric meiotic cell division in mouse oocytes, allowing for genomic reduction while maintaining essential building blocks. This finding provides insights into the molecular signals driving egg maturation and its significance for reproductive health.

In-shell vaccine for chick disease

A pre-hatching prototype vaccine virus providing immunity against infectious bronchitis virus (IBV) has been developed by scientists at the Institute for Animal Health and Intervet UK. The vaccine can be delivered to chicks still in their egg using robotic 'vaccinators' and has shown protection rates of up to 100 percent.

Durable critters providing insight for human egg preservation

Researchers explore using tardigrade-produced trehalose to preserve human eggs, offering a potential solution to successful embryo cryopreservation. The method has shown promising results in mouse eggs, and further research aims to apply it to human eggs and endangered species.

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Cracking the egg

Researchers identify 5,400 active genes in mouse eggs, including unique ones specific to egg cells, and find evidence of rapid change in critical mammalian genes. This study provides new information on the transition from unfertilized egg to fertilized embryo.

Bird moms manipulate birth order to protect sons

Researchers found that bird moms alter the birth order of eggs to shield sons from mites, speeding up their growth and survival. This strategy allows both males and females to thrive despite increased mortality risk from parasites.

Scientists crack genetic secrets of human egg

Researchers at Michigan State University have identified 5,331 unique genes in the human egg, which may hold the key to understanding fertility issues and developing new stem cell therapies. The discovery could also pave the way for the creation of healthy stem cells without the need for fertilized embryos.

FSU biologists uncover mechanisms that shape cells for better or worse

Researchers at FSU have identified a key component in cell polarity formation in fruit fly eggs, which also play a role in human diseases like muscular dystrophy and some cancers. The study's findings could lead to a better understanding of how cell-to-cell communication occurs in other types of cells and organisms.

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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

New technology addresses female fertility preservation

Researchers from Northwestern University have developed a three-dimensional culture system to preserve immature eggs for female fertility preservation. The technology, which mimics the ovary environment, has successfully led to the live birth of healthy mice from in vitro grown follicles.

Fertility hope as study shows eggs survive in older ovaries

Researchers find that female mice can maintain a steady number of eggs throughout adulthood, contradicting the long-held assumption that eggs decline with age. The study's findings suggest potential directions for ovarian stem cell research and fertility treatments.

New egg freezing technique offers hope to hundreds of women

A new egg freezing technique called Cryotop method has been developed, achieving a more than 90% survival rate for frozen-thawed eggs and a high pregnancy rate of nearly 42%. The process involves rapid freezing in a tiny amount of special vitrification solution, preventing ice crystals from forming damage to the egg. This technology op...

Egg donation for stem cell research -- balancing the risks and benefits

Egg donation for stem cell research is a contentious issue, with concerns over informed consent, health risks, and distributive justice. Researchers have developed guidelines to balance bioethical principles and reduce risks for donors, exploring alternative sources of eggs and incentivizing participation.

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Genetic tug of war determines sexual differentiation

Researchers found that the Wnt4 and Fgf9 genes are initially balanced before Sry triggers a cascade leading to testis formation. In contrast, an imbalance between these signals determines sex determination in vertebrates.

A surprising pair of proteins help make healthy eggs

Biologists at Brown University and the University of California–Berkeley have discovered a critical role for two proteins – TAF4b and c-Jun – in the growth and nurturing of granulosa cells that surround eggs. The finding provides important new information about fertility and may lead to better in-vitro fertilization therapies.

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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

New sonar method offers way to assess health of squid fisheries

Scientists develop a new sonar method to detect squid egg clusters, allowing for efficient mapping and estimation of squid populations. This technique has immediate potential to provide resource managers with sound scientific information to sustain the fishery and protect the species' genetic diversity.

Nitric oxide could extend fertility

Researchers found that exposing egg cells to nitric oxide can slow the hardening of their outer shells and increase the release of cortical granules, potentially extending their fertilizable time window. This could lead to improved fertility in women and reduce the risk of chromosomal abnormalities during early embryonic development.

Micro RNAs play role in egg making

Researchers have discovered that microRNAs are involved in the process of oogenesis, a complex regulatory mechanism controlling protein abundance. The findings suggest that miRNA dysfunction may contribute to certain forms of infertility.

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Cigarette smoke reduces transport of hamster eggs

A study by Christine Gieseke and Prue Talbot found that cigarette smoke significantly reduces the transport of hamster eggs through the oviduct. The researchers exposed cumulus-coated eggs to six types of cigarette smoke, resulting in a 40-55% increase in adhesion to the infundibulum and a 20-35% decrease in egg transportation rates.

Eggs from embryonic stem cells could benefit sterile women

Scientists have successfully developed ovarian structures containing eggs from embryonic stem cells, a breakthrough that could provide new hope for infertile couples. The method uses growth factors derived from testicular cells to induce the development of female reproductive cells.

Why being a teenage mum could be good for you!

Scientists at the University of Manchester studied the mating behaviour of dusky roaches to understand the mechanisms behind age-related decline in female fertility. The research suggests a natural biochemical reaction is to blame, where perfectly healthy eggs begin to die due to delayed reproduction.

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Scientists find a maturity gene

Researchers found that disabling a specific gene in fruit flies causes premature maturation, leading to small and misshapen adults. This study provides insight into the genetic mechanisms controlling human development from childhood to adolescence.

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Human eggs can develop from ovarian surface cells in vitro

Researchers have successfully developed human eggs from ovarian surface cells (OSE cells) in a laboratory setting. This breakthrough has potential applications in human reproduction, including increased chances of conception for women with reduced fertility and premature menopause.

Live faster, die younger: The shortest-living vertebrate

Researchers discovered a new species of coral-reef pygmy goby that lives for just 59 days, with daily mortality rates as high as 8%. The tiny fish lays only three clutches of eggs in its lifetime, contributing to the complex and hectic life cycle of reef fish.

Evolution of classical polyandry: three steps to female emancipation

The study explores how classical polyandry, a practice where multiple males mate with a single female, has evolved in different species. It reveals that this practice enhances female reproductive success and social stability through the provision of genetic diversity and protection from predators.

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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Babies born after surgery on eggs

Researchers use nuclear transfer to add women's own mitochondria to eggs, preventing inherited diseases caused by mitochondrial mutations. The technique involves adding the woman's own mitochondria to her eggs, reducing controversy and potential health risks compared to using donor mitochondria.

'Junk' DNA may be very valuable to embryos

Research suggests that retrotransposons, previously considered 'junk DNA', can initiate synchronous gene expression in mouse eggs and early embryos. This discovery may contribute to the reprogramming of the mammalian embryonic genome.

Parasitic cowbirds thrive with a less ruthless strategy than cuckoos

A new study reveals that cowbird chicks survive and even grow faster when raised in noisy nests with host siblings, rather than alone. By joining their nestmates in a chirping chorus, the cowbirds are able to monopolize food attempts from parents and reap the benefits of shared parental care.

Female infertility cAMP

Researchers created a mouse model with increased cAMP levels in eggs, leading to infertility. By blocking another protein, egg maturation was completed, revealing potential new contraceptive targets.

JCI Table of Contents, 15 July 2004

Researchers discovered that human stem cells can replenish muscle fibers in mice with Duchene muscular dystrophy, offering a potential treatment. In contrast, elevated cyclic AMP levels halted egg maturation in females, while HIV protease inhibitors impaired osteoclasts leading to bone loss.

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AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

New method of preserving fertility in young women with cancer

A new technique for preserving fertility in young women with cancer has been successfully used on eight female patients. The method involves removing immature eggs from the ovaries, maturing them through in-vitro maturation (IVM), and freezing them for later use.

Concerns remain about UVB damage to amphibians

Researchers say broad body of research shows UV-B radiation can cause severe damage to amphibian species from eggs to adults, including retinal damage and blindness. Amphibian declines are linked to multiple causes, but UV-B remains a significant concern.

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Human embryonic stem cells may promise medical advances

Researchers have developed versatile human embryonic stem cells capable of becoming any cell type, offering potential for transplantation medicine. The cells were created by transferring a somatic cell nucleus into an egg, reprogramming its genes to produce pluripotent stem cells.

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New insight into control of parental gene expression in eggs

Researchers at the University of Pennsylvania have discovered a critical regulatory role of protein CTCF in controlling gene imprinting in eggs. The study found that lower levels of CTCF resulted in higher DNA methylation and reduced fertility in female mice.

Egg-sharing does not damage a donor’s own chance of a baby say UK researchers

A study by the Lister Fertility Clinic in London found that women who participated in an egg-sharing program did not have a lower chance of getting pregnant or having a live birth compared to those who didn't participate. The researchers also found no evidence of increased risk of ovarian hyperstimulation syndrome among donors.

Nurseries in the deep sea

Marine biologists have discovered a unique undersea nursery off Northern California, where groups of fish and octopus brood their eggs. The discovery represents a new type of biological hot spot, with potential implications for conservation efforts.

Honeybee gene find ends 150-year search

Researchers isolated a honeybee gene called csd, revealing that female bees have two different versions of the gene that form an active protein triggering female development. This discovery explains how male and female bees develop from fertilized and unfertilized eggs, respectively.

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