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Advanced genome sequencing enables genetic diagnosis for complex psychiatric conditions

A new study describes a case where long-read genomic sequencing (LRS) was used to diagnose RFX3 haplo-insufficiency syndrome in a patient with autism spectrum disorder and intellectual disability. The study highlights the potential benefits of genetic testing in psychiatric care, including expediting workups for inpatient patients.

SourceRady Children's Institute for Genomic Medicine·JournalAmerican Journal of Psychiatry·TypeCase study·DateApr 9, 2025

Addressing societal concerns of genetic determinism of human behavior by linking environmental influences and genetic research

A new perspective article suggests that integrating environmental effects into genetic research is crucial to understand the intricate nature of gene-environment interactions. The authors propose expanding genome-wide association studies by incorporating environmental data, which could help mitigate deterministic thinking in genetics.

SourcePLOS·JournalPLOS Biology·TypeCommentary/editorial·DateFeb 27, 2024

MDMA (a.k.a. ecstasy) makes octopuses more social too

Researchers found that octopuses, which are typically solitary and asocial, become more interested in interacting with each other when under the influence of MDMA. The study suggests that common molecular pathways enable serotonin to encode social behaviors in both humans and octopuses.

SourceCell Press·JournalCurrent Biology·DateSep 20, 2018

New guide for finding genes linked with behavior

A new review article provides a novice-level introduction to applying molecular genomics techniques to study complex behavior. The guide recommends specific tools and collaborations for behavioral ecologists, aiming to bridge the gap between behaviorists and genome annotators.

SourceRice University·JournalNature Ecology & Evolution·DateFeb 12, 2018

Addressing pain and disease on the fly

Researchers at Brandeis University discover that fruit flies use two forms of TRPA1 to sense warmth and chemicals, providing potential solutions for chronic pain and disease control. The study's findings have implications for developing bug sprays and traps to combat mosquito-borne diseases.

SourceBrandeis University·JournalNature·DateDec 6, 2011