The launch of BioMed Central's Genome Medicine journal marks a significant milestone in the field of personalized medicine. The journal will focus on the latest technologies and findings impacting human health and disease, covering topics such as genomics, epigenetics, and computational approaches to disease management.
SourceBMC (BioMed Central)·JournalGenome Medicine·DateNov 12, 2008
Researchers discovered a positive role for gene recruitment to the nuclear periphery, with significant implications for cell polarity and development. The study's findings suggest a complex interplay between nuclear organization and transcriptional regulation.
SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateMay 14, 2005
The study reveals that antisense transcripts (SATs) are widely expressed in various mouse tissues and cell cultures, exhibiting tissue-specific expression patterns. SATs tend to be poly(A)-negative and enriched in the nucleus, suggesting a functional role in gene regulation.
SourceCold Spring Harbor Laboratory·JournalGenome Research·DateMar 14, 2005
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The Neisseria meningitidis genome contains hundreds of repetitive elements that facilitate genome fluidity and antigenic variation. The most abundant element is the neisserial DNA uptake sequence, which enables transformation among different species.
SourceMax-Planck-Gesellschaft·JournalNature·DateMar 27, 2000
Dr. Julie R. Korenberg's comprehensive map integrates three ways of looking at the human genome, marking critical points with fluorescent signposts for rapid translation of clinical problems into genome-based solutions. The guide has significant practical applications in cancer treatment and genetic diagnosis.
SourceCedars-Sinai Medical Center·JournalGenome Research·DateNov 28, 1999
A recent University of Georgia study suggests that retroviruses, including HIV, may have an ancient origin. Researchers analyzed the genome of a worm called Caenorhabditis elegans and found evidence of retroviral-like elements in its DNA. This finding challenges previous assumptions about the evolution of complex retroviruses.
SourceUniversity of Georgia·JournalGenome Research·DateOct 13, 1999