Articles tagged with Rheumatoid Arthritis
A nationwide study found that etanercept significantly slows or stops rheumatoid arthritis progression in nearly three-quarters of patients, with fewer side effects than methotrexate. The new use of etanercept as an early treatment offers a promising alternative for patients with advanced RA.
Research finds that rheumatoid arthritis patients experience longer hospital stays and higher total charges due to complications, with a notable impact on quality of life. The disease also results in increased healthcare utilization for general symptoms beyond musculoskeletal complaints.
Interleukin-1.com provides updated information on IL-1 role in RA, meeting a need for rheumatologists and health care professionals. The site offers resources, including a primer book and presentation materials, to enhance understanding of cytokine biology and its relevance to RA.
Top scientists from Harvard, Cornell, University of Dublin, and University of Colorado will discuss the molecular biology of IL-1 and its role in RA pathogenesis. They will also focus on new targets for treatment, such as bone degradation, and explore patient perspectives on quality of life.
New data suggest anakinra accelerates joint damage progression slowdown and improves health-related quality of life for RA patients. Studies found accelerated slowing of joint destruction with treatment, leading to nearly twice the rate of reduction in joint destruction as placebo groups.
A novel naked DNA vaccination technology has been developed to overcome autoimmune diseases like rheumatoid arthritis and multiple sclerosis. The vaccine introduces engineered genes that neutralize proinflammatory peptides, allowing the immune system to self-regulate its response and prevent disease progression.
A large-scale study suggests that coffee drinkers are at a higher risk of developing rheumatoid arthritis. The research found that those who consumed four or more cups of coffee daily were twice as likely to test positive for the disease, while those who drank 11 cups or more were nearly 15 times more likely.
A large study found that consuming four or more cups of coffee per day was twice as likely to test positive for rheumatoid factor, a hallmark indicator of the disease. Those who drank 11 or more cups daily were almost 15 times more likely to have rheumatoid factor.
Targeted Genetics Corporation has shown promise in its AAV gene therapy program for rheumatoid arthritis (RA), reducing ankle and hind paw swelling in preclinical studies. The treatment uses a recombinant TNFR:Fc fusion protein, which antagonizes the function of TNF-a, a key component of the inflammatory response.
The Prosorba® Column is a device that removes harmful antibodies and immune complexes from the blood of patients with rheumatoid arthritis. Patient trials are expected to evaluate its effectiveness and safety in treating this chronic inflammatory condition affecting over 250,000 Canadians.
Researchers found that delaying treatment by nine months results in significant permanent damage and reduced disease progression. Early therapy with a second-line agent like Hydroxychloroquine reduces the need for more expensive treatments, including surgery.
A new Greek study suggests that high consumption of olive oil and cooked vegetables may protect against rheumatoid arthritis. The study found a lower risk of developing RA among those who ate the highest amount of cooked vegetables, with a 75% lesser risk compared to those in the lowest category.
Rheumatoid arthritis patients receiving a single dose of Alexion's 5G1.1 showed significant reduction in joint pain and symptoms compared to placebo-treated patients, with 50% achieving an ACR20 score. The company is currently enrolling up to 200 patients in a Phase II efficacy trial employing multiple doses of 5G1.1.
Carolyn Bertozzi, an organic chemist at the University of California Berkeley, receives the 1999 Arthur C. Cope Scholar Award for her work on using sugars attached to cell surfaces to understand and treat diseases like rheumatoid arthritis and cancer. Her research focuses on how sugar molecules direct cell communication within tissues.
A recent study published in the Proceedings of the National Academy of Sciences suggests that green tea polyphenols may help prevent and reduce the severity of rheumatoid arthritis. The study found that mice given green tea polyphenols were significantly less likely to develop arthritis, with only 44% developing the condition compared ...
The US FDA approves ENBREL, a biologic response modifier, for moderately to severely active polyarticular-course juvenile rheumatoid arthritis in patients with an inadequate response to other treatments. The treatment has shown a clinical response in 74% of study participants.
The six-month study demonstrated significant improvement in symptoms and disease activity in patients with rheumatoid arthritis, establishing a foundation for FDA approval of ENBREL. The results support the use of etanercept as an additional treatment option for these patients.
Researchers found that injecting methotrexate significantly improved patient health and reduced costs for those with juvenile rheumatoid arthritis or rheumatoid arthritis. The study involved 52 patients, with 73% switching to injection treatment due to dissatisfaction with oral method side effects.
A nationwide effort to find genes that determine susceptibility to rheumatoid arthritis has been launched, with researchers collecting medical information and genetic material from 1,000 families. The project aims to identify genetic regions shared by affected siblings, which may contain genes involved in the disease.