The BIOFAB facility aims to produce thousands of standardized DNA parts, shortening the development time and lowering the cost of synthetic biology for academic or biotech laboratories. The project will enable researchers to mix and match genetic parts in synthetic organisms to produce new drugs, fuels, or chemicals.
The Wilson Center's Synthetic Biology project has received two National Science Foundation grants to support research on the implications of synthetic biology for sustainability science and policy. The projects will explore emerging issues in synthetic biology, including its potential contribution to sustainable development.
The National Science Foundation has awarded a grant to develop GenoCAD, a web-based Computer Assisted Design environment for synthetic biology. The platform allows users to design complex DNA sequences in minutes and will support teams of undergraduate students enrolled in iGEM.
Researchers created 'bacterial computers' that can solve complex mathematical problems, such as the Hamiltonian Path Problem and Burnt Pancake Problem. The innovation uses synthetic biology techniques to enable living cells to perform calculations, opening up new applications for biology and mathematics.
Biomedical engineers at Boston University have developed synthetic gene networks that enable bacteria to count discrete events, opening up potential applications in drug delivery and environmental sensing. The researchers designed two separate systems, the Riboregulated Transcriptional Cascade and DNA Invertase Cascade, which can be us...
A new report by Michael Rodemeyer examines the benefits and drawbacks of regulating synthetic biology using the current U.S. biotechnology framework. While early applications may be adequately covered, advances in the field are expected to create significant challenges for regulatory agencies, including the EPA and FDA.
Researchers have developed a microbial-based method to produce artemisinin, the most powerful anti-malarial drug, at lower costs. This technology can restrict access to artemisinin and delay malaria parasite resistance.
Amyris Biotechnologies has successfully increased the production of amorphadiene to 25g/L through E. coli fermentations, a crucial step towards commercially producing artemisinin precursors. This achievement demonstrates the potential of synthetic biology and fermentation to create a consistent and affordable source of artemisinin for ...
Biochemist David Deamer explores the molecular self-assembly processes that led to the first protocells nearly 4 billion years ago. He proposes a combinatorial chemistry approach to understanding how life began, suggesting complex systems of molecules assembled on early Earth.
The Synthetic Biology Project aims to minimize risks and maximize benefits through rigorous analysis and public engagement. The project explores governance options, examines public perceptions, and identifies knowledge gaps in synthetic biology.
Researchers have developed a synthetic biology advance that creates a stable, fast and programmable genetic clock in E. coli cells. The clock's blink rate changes when temperature, energy source or other environmental conditions change, enabling the detection of environmental information.
The UK is launching a Synthetic Biology Initiative with £900,000 funding to establish a world-leading research community. The project aims to bring together biologists, engineers, and computer scientists to tackle future challenges such as sustainable power generation and medical applications.
Researchers have successfully synthesized a DNA-based memory loop in yeast cells, demonstrating the ability to create a mathematical model that predicts how such a device might work. The memory loop continued throughout many cell divisions, showcasing the potential for biological black boxes with specific functions.
MIT and BU researchers develop modular system to design phages targeting specific bacterial biofilms, achieving high success rates. The technology has potential applications in treating infections and cleaning products.
Scientists from leading institutions worldwide issue a statement highlighting the critical importance of synthetic biology, citing its potential to solve eco-safe energy issues, outbreaks of malaria, and more. The Ilulissat Statement emphasizes the need for an international effort to advance research while developing protective measures.
Glenn Micalizio, Yale Assistant Professor, has been awarded the Eli Lilly Grantee Award for his research on simplifying organic chemistry. His work focuses on developing new methods for forming carbon–carbon bonds to facilitate drug discovery.
Molecular Systems Biology is a new journal that publishes papers on complex biological systems using molecular components and their interactions. The journal features innovative technology for formal descriptions of biological systems and sharing of data in widely-used XML-based formats.
A partnership between OneWorld Health, University of California - Berkeley, and Amyris Biotechnologies aims to produce an inexpensive antimalarial drug using synthetic biology. The goal is to reduce the cost of treatment to under $1 per adult course, making it more accessible to millions in developing countries.