Articles tagged with Deep Brain Stimulation
A study by Cedars-Sinai Medical Center's Movement Disorders Program identified variables that affect impedance in deep brain stimulation devices, which can alter patient outcomes. Regular clinic visits are crucial to ensure steady levels of stimulation and prevent side effects.
A long-term study of patients with hereditary dystonia found symptom severity dropped to less than 20% within two years after device implantation. Sixty-one percent were able to discontinue all medications and 91% could discontinue at least one class of drugs.
Scientists at UCSF have discovered a way to detect abnormal brain rhythms associated with Parkinson's disease by implanting electrodes within the brains of people with the disease. This finding may lead to developing next-generation brain stimulation devices to alleviate symptoms.
Miniature, ultra-flexible electrodes developed in Switzerland may improve Deep Brain Stimulation (DBS) treatment for Parkinson's disease and other conditions. These new electrodes allow for more precise directional stimulation, reducing side effects and enhancing therapeutic effectiveness.
A large study found that two-thirds of eligible patients experience significant and lasting benefits from deep brain stimulation (DBS) for neuropathic pain. Benefits vary by cause, with improved outcomes seen in patients with amputation and stroke. Continued improvement is observed with longer follow-up.
Researchers found that two patients with severe dystonia experienced prolonged symptom relief despite interrupted deep brain stimulation therapy. The study suggests that younger brains and shorter disease duration may be more responsive to treatment.
Researchers at Mayo Clinic have developed a novel system to monitor real-time chemical changes in the brain using fast scan cyclic voltammetry and wireless neurochemical sensing. This technology can help treat brain disorders by adjusting neurotransmitter levels, reducing symptoms such as tremors.
Researchers used deep brain stimulation to treat binge eating in mice and found a significant reduction in consumption of high-fat food. The study suggests that deep brain stimulation may be an effective therapy for obesity by modulating activity of neurons expressing the type 2 dopamine receptor.
Researchers found that deep brain stimulation improved motor symptoms, including reduced tremors and dyskinesia, and increased periods of effective symptom control. Patients also reported improvements in daily activities, mobility, emotional state, social support, and physical comfort.
Pitt mathematicians collaborate with neurobiology researchers to study the transfer of signals between brain regions and develop less invasive treatments. Their study may guide the creation of more effective deep brain stimulation procedures.
Researchers found that while deep brain stimulation has increased acceptance among referring physicians for Parkinson's disease and other movement disorders, only half of recommended patients are appropriate candidates for immediate therapy. This suggests that physicians have become more aware and accepting of the treatment, but may re...
Deep brain stimulation is a therapy approved by the FDA for certain treatment-resistant dystonias and has shown sustained benefit for up to three years. Michele Tagliati, a movement disorders expert, led an international task force that reviewed current practice and research on DBS for dystonia.
A new MRI device guides surgeons during electrode implantation, potentially cutting surgery time in half and making the procedure faster and more comfortable for patients. The device was developed by a team of UCSF neurosurgeons and radiologists to improve deep brain stimulation outcomes for Parkinson's disease patients.
A study of 31 patients found that 77% stopped taking anti-tremor medications within a year after DBS surgery, with symptom improvement rates varying among patients. Long-term effects and potential need for continued medication are areas of future research focus.
Earlier deep brain therapy shows better, quicker results for patients with potentially crippling dystonia. A study found that those treated earlier have better general outcomes, while age at surgery influences the time necessary to achieve optimal benefit.
A new study at UCSF reveals that brain implant surgeries can dramatically improve life for people with severe cervical dystonia. The procedure targets a previously untested part of the brain, showing promise in reducing pain and spasms while improving quality of life.
Scientists identified hyperactive nerve cells in a tiny brain structure linked to depression, which can be reversed with deep brain stimulation. The study provides a cellular mechanism for depressive disorders and lends support to the use of this treatment approach.
Researchers propose a new target structure for deep brain stimulation to treat depression, with promising results. The method has already shown significant improvement in mood for half of patients with the most severe depression, and may lead to even better success rates with fewer side effects.
A new study by Michele Tagliati and colleagues found that patients with deep brain stimulation experienced no significant progression of motor symptoms over five years. The research suggests that the therapy may actually stabilize these symptoms, challenging previous assumptions about Parkinson's disease progression.
Research consensus establishes DBS as a treatment option for patients with severe Parkinson's symptoms, including tremors and motor fluctuations. The study provides guidelines for patient selection and surgical approach, emphasizing the importance of experienced teams and neurosurgeons.
A recent study published in The Lancet Neurology found that deep brain stimulation improves quality of life, mobility, and activities of daily living in advanced Parkinson's disease patients, while also reducing dyskinesia and off time. However, the procedure carried a higher risk of serious adverse events.
A new study from University of Bonn suggests that deep brain stimulation can significantly improve depression in half of patients, who had previously not responded to other therapies. The treatment involves implanting electrodes in the nucleus accumbens, a key area of the brain's reward system.
A study of 15 patients with severe Tourette syndrome found that deep brain stimulation reduced tic frequency by 52% on average and improved OCD symptoms. The treatment showed no significant effect on thinking abilities.
Bilateral pallidal deep brain stimulation has been shown to improve movement skills and quality of life in some patients with dystonia-choreoathetosis cerebral palsy. The treatment resulted in sustained improvement in motor symptoms, but variability in response was observed.
Patients with advanced Parkinson's disease who received deep brain stimulation treatment had significant improvements in movement skills and quality of life after six months. However, the treatment was also associated with a higher risk of serious adverse events, including surgical site infections and nervous system disorders.
Researchers find that adenosine, a sleep-inducing brain chemical, plays a central role in deep brain stimulation's success. The technique disrupts abnormal nerve signals and alleviates symptoms in patients with Parkinson's disease and other brain disorders.
Biomedical engineers at Duke University found that deep brain stimulation alleviates disease symptoms by creating an informational lesion through rapid-fire electrical pulses. This technique can be reversible and adjustable, offering a promising treatment for movement disorders and other conditions.
A study at the University of Bonn found that two men and a woman with severe depression experienced significant improvements in their symptoms after receiving deep brain stimulation. The therapy, which targets the nucleus accumbens area of the brain, showed promising results despite the small patient group.
Researchers found that direct neurologist involvement improves Parkinson's disease symptoms for patients undergoing deep brain stimulation, leading to reduced tremors and medication dosages. This study emphasizes the importance of personalized care by experts in movement disorders and deep brain stimulation.
Researchers seek to confirm that deep brain stimulation can help patients with severe obsessive-compulsive disorder (OCD) and understand the disrupted brain network. A clinical study will examine the effects of DBS at different sites and assess treatment effectiveness.
The American Academy of Neurology has released new guidelines for treating essential tremor, recommending medications such as propranolol and primidone to reduce limb tremors. Surgery is also an option when drug therapy is ineffective, with deep brain stimulation found to be more effective than thalamotomy in reducing tremors
The American Academy of Neurology has published a new guideline recommending medications such as propranolol, primidone, sotalol, and atenolol to treat limb and head tremors in patients with essential tremor. These medications can help manage tremors and improve daily life.
A study examining reasons for suboptimal outcomes following deep brain stimulation surgery found issues with screening, diagnosis, and device programming. The researchers successfully salvaged 51% of failed procedures through reprogramming, medication adjustments, and electrode replacement.
A study published by the American Academy of Neurology found that deep brain stimulation significantly improved dystonia symptoms in seven patients, with three experiencing near-complete resolution. The treatment showed promise as a safe and effective therapy for previously untreatable diseases.
Despite being a significant advancement in Parkinson's disease treatment, only 7% of eligible patients in G5 European countries have received deep brain stimulation therapy. Inconsistent funding support and low awareness among general practitioners are major barriers to access.