Articles tagged with Neuromodulators
Researchers propose an AI framework, called interoceptive AI, that uses internal states to inform learning and decision-making in dynamic environments. This approach treats internal conditions as a continuous source of context, influencing what an agent learns, prioritizes, and does.
Researchers at MIT's Picower Institute mapped the neural circuits that enable C. elegans worms to navigate towards attractive odors and avoid unappealing ones. The study revealed a specific sequence of neural activation, involving key neurons and the neuromodulator tyramine.
A Korean research team developed a spinal cord stimulator that softens upon contact with bodily fluids, mimicking surrounding nerve tissue. The device uses liquid metal and variable stiffness structures to achieve stable signal transmission and reduced costs.
Researchers at MIT discovered how an immune system molecule, interleukin-1 beta, triggers a brain circuit to shut down social behavior in mice. The study found that the molecule activates neurons in the dorsal raphe nucleus, leading to social withdrawal and lethargy.
Researchers have successfully controlled a dexterous robotic hand using noninvasive EEG-based Brain-Computer Interfaces (BCIs) for individual finger movements. The study demonstrates real-time brain decoding and motor imagery control, paving the way for potential applications beyond basic communication to intricate motor control.
Astrocytes, once thought to be supporting cells, are active players in neuromodulation, controlling neuronal activity and behavior. The discovery of a biochemical circuit involving ATP and adenosine reveals a slower time scale for modulation compared to neural circuits.
Researchers discovered that C. elegans worms reconfigure brain cells and peptides to cope with infection, enabling them to survive longer. The study reveals unexpected findings on the role of neurons and neuromodulators in adaptive responses.
Researchers used low-intensity ultrasound to target and alter the default mode network of the brain, reducing connectivity and enhancing mindfulness. The technique, called transcranial-focused ultrasound (TFUS), can induce meaningful effects with just five minutes of stimulation.
Researchers at Carnegie Mellon University have successfully integrated focused ultrasound stimulation into noninvasive BCIs, significantly boosting signal quality and enabling bidirectional brain-computer interfaces. The technology allows individuals to control a cursor or robotic arm using only their thoughts.
Researchers developed a novel light-sensitive drug that enhances extracellular adenosine activity, inducing sleep artificially without genetic modification. The drug overcomes issues with conventional photosensitive drugs, showcasing optochemistry's potential in targeting A2A receptors and regulating brain function.
Neurons exhibit 'mixed selectivity,' integrating multiple inputs and computations, ensuring focused cognition. The brain employs mechanisms like oscillations and neuromodulators to recruit neurons and tune them to relevant information.
Researchers at University of Tsukuba found that hydrogen sulfide production within the respiratory center alters neurotransmissions, disrupting breathing patterns. The study identified variations in this mechanism across different regions, revealing a modulating influence on neural circuits contributing to respiration stability.
Scientists have discovered that genes required for complex behaviors like learning, memory, and aggression originated around 650 million years ago. This finding has significant implications for understanding the evolutionary origin of these behaviors and their neural circuits.
Rice University engineers developed ultraflexible nanoelectrodes that can deliver high-resolution stimulation therapy with minimal scarring and degradation. The devices showed precise spatiotemporal stimulus control, enabling the development of new brain stimulation therapies for patients with impaired sensory or motor functions.
A new AI-based dynamic brain imaging technology has been introduced by Carnegie Mellon University, which can map out rapidly changing electrical activity in the brain with high precision and speed. The technology uses deep learning approaches to translate scalp EEG signals back to neural circuit activity without human intervention.
Researchers from Rice University, Duke University, Brown University and Baylor College of Medicine developed a magnetic technology to wirelessly control neural circuits in fruit flies. They used genetic engineering to express heat-sensitive ion channels in neurons that control the behavior, and iron nanoparticles to activate the channels.
A new MIT study finds that noradrenaline helps the brain learn from surprising outcomes by stimulating behavior that leads to a reward, particularly in uncertain situations. The researchers also discovered that noradrenaline promotes taking a chance on getting a reward, even when the outcome is unknown.
Scientists at KAIST have proposed a novel 'stashing system' inspired by the human brain's neural activity, which efficiently handles mathematical operations for artificial intelligence. This technology reduces power consumption by 37% while maintaining accuracy, paving the way for next-generation semiconductor chips.
Researchers identified three KCTD proteins that modulate neurotransmitter activity, enabling fine-tuned movement. Their elimination enhances cAMP production and sensitivity to dopamine in neurons.
The new project posits that deep neural networks struggle with real-world problems due to an overemphasis on neurons, which neglect the role of astrocytes. Integrating astrocytes could enhance DNN efficiency and performance.
Researchers found that acetylcholine, a neuromodulator, enhances neural discrimination of tones from noise stimuli, potentially contributing to processing important acoustic signals like speech. The study also identified novel connections between the modulatory centers and the auditory system.
A Penn expert is investigating the neurological basis of loss of smell, which can be an early indicator of neurodegenerative diseases like Alzheimer's and Parkinson's. The researcher found evidence suggesting damage to neurotransmitter and neuromodulator receptors in the forebrain may be a common factor behind smell loss.
Researchers at Max Planck Florida Institute for Neuroscience developed iTango, a light-sensitive technique to visualize and manipulate neuromodulation. The technique allows for increased spatial and temporal precision, enabling the identification of specific neurons impacted by neuromodulation and control over behavior.
Researchers have developed a new technique to observe brain activity in real-time, enabling them to study how we learn and develop addictions. The 'CNiFERs' tool measures the release of specific neurotransmitters, revealing the timing of dopamine surges during learning and addiction processes.
Researchers have developed a tailored small molecule that dramatically reduces brain damage after a stroke by inhibiting the production of hydrogen sulfide (H2S) in the brain. The study shows a 70% reduction in stroke severity when tested in rats.