Articles tagged with Neuromodulators
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at MIT discovered how an immune system molecule, interleukin-1 beta, triggers a brain circuit to shut down social behavior in mice. The study found that the molecule activates neurons in the dorsal raphe nucleus, leading to social withdrawal and lethargy.
Researchers have successfully controlled a dexterous robotic hand using noninvasive EEG-based Brain-Computer Interfaces (BCIs) for individual finger movements. The study demonstrates real-time brain decoding and motor imagery control, paving the way for potential applications beyond basic communication to intricate motor control.
Astrocytes, once thought to be supporting cells, are active players in neuromodulation, controlling neuronal activity and behavior. The discovery of a biochemical circuit involving ATP and adenosine reveals a slower time scale for modulation compared to neural circuits.
Researchers discovered that C. elegans worms reconfigure brain cells and peptides to cope with infection, enabling them to survive longer. The study reveals unexpected findings on the role of neurons and neuromodulators in adaptive responses.
Researchers used low-intensity ultrasound to target and alter the default mode network of the brain, reducing connectivity and enhancing mindfulness. The technique, called transcranial-focused ultrasound (TFUS), can induce meaningful effects with just five minutes of stimulation.
Researchers at Carnegie Mellon University have successfully integrated focused ultrasound stimulation into noninvasive BCIs, significantly boosting signal quality and enabling bidirectional brain-computer interfaces. The technology allows individuals to control a cursor or robotic arm using only their thoughts.
Researchers developed a novel light-sensitive drug that enhances extracellular adenosine activity, inducing sleep artificially without genetic modification. The drug overcomes issues with conventional photosensitive drugs, showcasing optochemistry's potential in targeting A2A receptors and regulating brain function.
Neurons exhibit 'mixed selectivity,' integrating multiple inputs and computations, ensuring focused cognition. The brain employs mechanisms like oscillations and neuromodulators to recruit neurons and tune them to relevant information.
Researchers at University of Tsukuba found that hydrogen sulfide production within the respiratory center alters neurotransmissions, disrupting breathing patterns. The study identified variations in this mechanism across different regions, revealing a modulating influence on neural circuits contributing to respiration stability.
Scientists have discovered that genes required for complex behaviors like learning, memory, and aggression originated around 650 million years ago. This finding has significant implications for understanding the evolutionary origin of these behaviors and their neural circuits.
Rice University engineers developed ultraflexible nanoelectrodes that can deliver high-resolution stimulation therapy with minimal scarring and degradation. The devices showed precise spatiotemporal stimulus control, enabling the development of new brain stimulation therapies for patients with impaired sensory or motor functions.
A new AI-based dynamic brain imaging technology has been introduced by Carnegie Mellon University, which can map out rapidly changing electrical activity in the brain with high precision and speed. The technology uses deep learning approaches to translate scalp EEG signals back to neural circuit activity without human intervention.
Researchers from Rice University, Duke University, Brown University and Baylor College of Medicine developed a magnetic technology to wirelessly control neural circuits in fruit flies. They used genetic engineering to express heat-sensitive ion channels in neurons that control the behavior, and iron nanoparticles to activate the channels.
A new MIT study finds that noradrenaline helps the brain learn from surprising outcomes by stimulating behavior that leads to a reward, particularly in uncertain situations. The researchers also discovered that noradrenaline promotes taking a chance on getting a reward, even when the outcome is unknown.
Scientists at KAIST have proposed a novel 'stashing system' inspired by the human brain's neural activity, which efficiently handles mathematical operations for artificial intelligence. This technology reduces power consumption by 37% while maintaining accuracy, paving the way for next-generation semiconductor chips.
Researchers identified three KCTD proteins that modulate neurotransmitter activity, enabling fine-tuned movement. Their elimination enhances cAMP production and sensitivity to dopamine in neurons.
The new project posits that deep neural networks struggle with real-world problems due to an overemphasis on neurons, which neglect the role of astrocytes. Integrating astrocytes could enhance DNN efficiency and performance.
Researchers found that acetylcholine, a neuromodulator, enhances neural discrimination of tones from noise stimuli, potentially contributing to processing important acoustic signals like speech. The study also identified novel connections between the modulatory centers and the auditory system.
A Penn expert is investigating the neurological basis of loss of smell, which can be an early indicator of neurodegenerative diseases like Alzheimer's and Parkinson's. The researcher found evidence suggesting damage to neurotransmitter and neuromodulator receptors in the forebrain may be a common factor behind smell loss.
Researchers at Max Planck Florida Institute for Neuroscience developed iTango, a light-sensitive technique to visualize and manipulate neuromodulation. The technique allows for increased spatial and temporal precision, enabling the identification of specific neurons impacted by neuromodulation and control over behavior.
Researchers have developed a new technique to observe brain activity in real-time, enabling them to study how we learn and develop addictions. The 'CNiFERs' tool measures the release of specific neurotransmitters, revealing the timing of dopamine surges during learning and addiction processes.
Researchers have developed a tailored small molecule that dramatically reduces brain damage after a stroke by inhibiting the production of hydrogen sulfide (H2S) in the brain. The study shows a 70% reduction in stroke severity when tested in rats.