A new study identified unique subpopulations of fat cells with complex predicted functions, and even found differences between human fat tissues in intercellular communication. The discovery provides a basis for further research to advance personalized medicine in obesity.
Researchers studied the effects of resveratrol on circadian clock gene expression in young and older human adipose-derived progenitor cells. They found increased levels of some components in older-APCs compared to young-APCs, but also observed gained rhythmicity of some components after resveratrol treatment.
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A 29-year-old woman was hospitalized with sepsis 14 months after a dermal filler injection, revealing rare bacterial causes and increasing awareness of the need for cosmetic patients and healthcare professionals.
Researchers mapped out changes in fat tissue during intermittent fasting, showing visceral 'belly' fat becomes resistant to weight loss by adapting to repeated fasting periods. The study provides insights into the mechanisms behind this resistance and potential diet interventions.
Researchers found that biliverdin-binding serpins (BBSs) are responsible for the blue-green coloration of frogs, which helps with camouflage. BBSs alter the spectral absorbance of biliverdin and fine-tune the frog's reflectance spectra.
A new anatomic study highlights critical technical issues to ensure safe performance of the Brazilian butt lift, a procedure using patient's own fat to augment and improve buttock appearance. Researchers recommend injecting only under skin, never into muscle, to prevent serious complications.
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Researchers at Brigham and Women's Hospital have developed an intelligent-injector for tissue-targeting (i2T2) that detects changes in resistance to deliver medication safely and effectively. The device was tested on animal models and found to precisely deliver medication without overshoot injuries.
Scientists discover that expanding subcutaneous white fat tissue can improve insulin sensitivity and reduce inflammation in obese individuals. A microRNA called miR-30a plays a crucial role in this process, protecting fat cells from inflammation and leading to improved metabolic health.
Researchers found that subcutaneous fat has an intrinsic circadian rhythm in insulin sensitivity, peaking at noon and decreasing by midnight. This internal clock may contribute to daily rhythms in glucose tolerance observed in humans.
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A new study found that 24 hours of fasting induces a miRNA-149-3p-mediated subcutaneous to visceral fat switch via suppression of PRDM16 in mice. This switch may play a crucial role in maintaining energy balance and could have implications for obesity and metabolic disease prevention.
A recent study by Children's Hospital Los Angeles found that excess fat accumulation in the lower legs of children with myelomeningocele is primarily associated with muscle-associated adipose tissue. This type of fat has been linked to increased risk for metabolic disorders, including diabetes.
Global gene expression analysis reveals distinct molecular differences between perivascular and subcutaneous fat tissues. Perivascular fat tissue is highly inflamed in humans with coronary artery diseases, suggesting it as a key player in disease formation.
Scientists have successfully fused human stem cells derived from fat tissue with muscle cells from rat hearts, forming new muscle cells that beat. This achievement demonstrates the potential for regenerative medicine to heal damaged hearts without transplantation.
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A recent study published in the American Journal of Clinical Nutrition found that individuals who consume several servings of whole grains per day and limit their intake of refined grains appear to have less visceral adipose tissue, a key factor in cardiovascular disease and type 2 diabetes. The study observed a 10% lower VAT volume in...
A new study from the University of Cincinnati found that Bisphenol A (BPA) suppresses a key hormone, adiponectin, which regulates insulin sensitivity and puts people at risk for metabolic syndrome. The study used fresh human fat tissues and found that BPA exposure resulted in suppression of this hormone.
Researchers found that transplanted subcutaneous fat into mice visceral cavity showed improved blood sugar and insulin levels, while visceral fat had detrimental effects. The findings suggest fat cells in different depots have intrinsically different properties.
Researchers measured the force required to overcome tissue-needle connection during acupuncture needling, finding a significant pullout force when needles were rotated. The study suggests that layers superficial to muscle may be involved in the body's response to acupuncture, with future research focusing on connective tissue's role.