Articles tagged with Cyclodextrins
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at Doshisha University have developed a synthetic, nontoxic antidote for hydrogen sulfide poisoning. The new compound, met-hemoCD-I, converts toxic hydrogen sulfide into harmless sulfite and sulfate ions.
Researchers developed a novel cyclic molecule that selectively traps phosphate species through multi-point hydrogen bonding in harmony with water molecules. The findings provide guidelines to design new cyclic molecules for aqueous environments, significant for materials development.
Researchers from Osaka University have developed tough biodegradable plastics with movable cyclodextrin crosslinks, which improve both durability and degradation capabilities. The new polymers can be broken down by enzymes into useful precursor molecules, reducing waste generation.
Scientists have created mirror-image cyclodextrins in the laboratory, which could make it easier to formulate and deliver complex medications. These discoveries may also lead to improved treatment of cardiovascular diseases caused by atherosclerotic plaques.
Scientists at DGIST developed a triboelectric nanogenerator using cyclodextrin, a green material from starch, to convert mechanical energy into electricity. The device can be reused and is biocompatible, making it suitable for wearable applications.
Researchers at KAIST designed nanoparticles that significantly reduce cholesterol and macrophage foam cells in arteries, two key triggers of atherosclerotic plaque. The combination drug delivery therapy showed great potential for treating and preventing atherosclerosis with reduced side effects.
Researchers have developed Pillar[n]MaxQ molecules that bind neuromuscular blocking chemicals with high specificity and strength. These new molecular containers show promise for eliminating toxins and malodorous substances in water, outperforming existing macrocyclic agents.
A new breakthrough in sensor technology uses a one-molecule-thick coating to improve detection of diseases and detect doping in sports. The coating, based on beta-cyclodextrin, produces sensors around ten times more sensitive than existing ones, allowing for earlier diagnosis and detection at lower concentrations.
A clinical trial shows promise for treating Niemann-Pick type C by slowing disease progression with cyclodextrin. The study found significant improvements in gait, cognition, and speech, with half of patients experiencing no worsening or improvement in neurological severity score.
Researchers developed a novel approach to strengthen polymer gels by modifying the length of polymer threads per molecular beads, increasing fracture resistance and strain strength. The technique enables fabrication of polymer gels with desired mechanical properties.
Researchers found that cyclodextrin reduces atherosclerotic plaques by reprogramming macrophages and dissolving cholesterol crystals. The treatment prevents plaque formation and reduces existing plaques in mice and human carotid arteries, pointing to cholesterol crystals as a target for atherosclerosis treatment.
Researchers at the University of Bonn discovered that cyclodextrin promotes the breakdown of cholesterol deposits in arteries, reducing inflammation and plaque formation. The ring-shaped sugar increases natural mechanisms for cholesterol breakdown and reduces inflammatory response, offering a potential new treatment for atherosclerosis.
Researchers are developing treatments for Niemann-Pick disease type C using cyclodextrin and delta-tocopherol, which have shown promise in studies of patient skin cells and animal models. The goal is to reduce lipid accumulation and improve symptoms in patients with this devastating rare disease.
A clinical trial to evaluate cyclodextrin as a potential treatment for Niemann-Pick disease type C1 has begun at the NIH Clinical Center. The disease, caused by cholesterol accumulation in cells, leads to progressive impairment of motor and intellectual function.
University of Illinois scientists have discovered a method to reduce the bitterness of ginseng in energy drinks by over half using cyclodextrins. This innovation could improve the health benefits of these beverages and expand their market, particularly in the US energy drink industry.
Researchers aim to overcome technical hurdles in new gene sequencing technology that could make genetic medicine possible with rapid, accurate, and low-cost sequencing of single DNA molecules. The method uses Atomic Force Microscopy and cyclodextrin molecules to read the sequence of amino acid code in the human genome.