Articles tagged with Organocatalysis
Researchers at Tsinghua University developed a novel method for synthesizing chiral alpha-amino acids using a photo-driven nitrogen heterocyclic carbene catalyst. The reaction achieves good to excellent enantioselectivity and substrate versatility, enabling the rapid preparation of structurally diverse chiral alpha-amino acid derivatives.
Researchers at The University of Osaka have invented a novel, unsymmetrical hetero[8]circulene molecule with unique properties that make it a potent organic photocatalyst. The molecule can speed up chemical reactions triggered by light, paving the way for sustainable and inexpensive material creation.
Researchers from Ruhr-University Bochum developed a novel approach to create salts that catalyze specific reactions. The cation and anion components of the salt play crucial roles in ensuring the correct handedness of the resultant molecule.
A team of researchers from Okayama University developed a novel phenothiazine-based organic photoredox catalyst with enhanced stability and recyclability. The new catalyst, PTHS, features a spiral structure that provides improved stability and can be recycled multiple times without losing catalytic activity.
Researchers from ICIQ describe a circular process to recycle biobased polycarbonates, which can contribute to a more sustainable circular economy. The study uses a multi-task catalyst to promote depolymerization and repolymerization of the polymer.
Researchers at the University of Münster have developed a reaction cascade to produce fluorinated molecules, reducing costs and waste in complex synthesis strategies. The 'molecular origami' approach generates new class of di- and trifluorinated molecules in a single operation.
Scientists at the National University of Singapore have developed a new method for synthesizing organosilanes using eosin Y, a low-cost and readily available dye molecule. This enables stepwise customised functionalisation of multihydrosilanes to access fully substituted silicon compounds.
Researchers developed a machine learning model using advanced 2D chemical descriptors to predict highly selective asymmetric catalysts without quantum chemical computations. The model demonstrated high accuracy in predicting catalyst structures and selectivity, outperforming existing methods.
Researchers at CiQUS developed a new methodology for synthesizing chiral benzazepines, a highly interesting bioactive molecule. The method uses a palladium metal and a newly designed chiral ligand to activate specific C-H bonds, enabling the efficient production of these compounds.
Researchers at Karolinska Institutet have improved the ability of a protein to repair oxidative DNA damage, creating a new drug development concept. The technique can lead to improved treatments for diseases involving oxidative stress.
Current Organocatalysis journal to be indexed in Scopus, expanding its reach. The journal covers various aspects of organocatalysis, including drug discovery and green chemistry.
Current Organocatalysis and Synthetic Methods is an international peer-reviewed journal covering organo homogeneous/heterogeneous catalysis, mechanistic studies, and kinetics. The journal publishes new methods, reagents, and mechanisms for chemical synthesis, with a focus on green chemistry and chemoenzymatic reactions.
A new organocatalyst, Hua Cat, developed at Oregon State University is now available for commercial use, promising to make new drug development less costly and more environmentally friendly. The catalyst has shown great promise in various applications, including the treatment of cancer, heart disease, and infectious diseases.