Articles tagged with Half Life
Researchers at Waseda University develop a new imaging technique that uses neutron activation to transform gold nanoparticles into radioisotopes, enabling long-term tracking of their movement in the body. This breakthrough could lead to more effective cancer treatments and precision monitoring of drug distribution.
Researchers at GSI/FAIR discovered the shortest-lived superheavy nucleus, Rf-252, marking the position of the island's shoreline in nuclei of rutherfordium. The results confirm theoretical predictions and enable further exploration of phenomena associated with isomer states and inverted fission stability.
A long-acting biologic with transmucosal transport properties has been developed to block cellular infection of all SARS-CoV-2 variants. The biologic utilizes a soluble recombinant human ACE2 protein fused to an engineered human albumin variant, offering improved pharmacokinetic properties and delivery across selective barriers.
Researchers from Vienna University of Technology and Leibniz University of Hannover have found the solution to the wild boar paradox. The radioactivity in wild boar meat remains high due to the accumulation of cesium-137 from nuclear weapons tests, which is also present in deer truffles that are particularly favored by wild boars.
The addition of antioxidants to cell cultures can improve the production of monoclonal antibodies by reducing oxidative stress and increasing cell viability. This has potential benefits for therapies targeting cancer and autoimmune diseases.
Researchers measured the half-lives of five exotic isotopes at the Facility for Rare Isotope Beams (FRIB), a DOE Office of Science user facility. The study provides fundamental information about nuclei near their limits of existence, testing models of the atomic world and advancing research in astrophysics and nuclear physics.
A new atomic nucleus, 149-Lutetium, has been synthesized at the University of Jyvaskyla, emitting protons with a record-breaking rate. This discovery provides exceptional decay properties and breaks previous records for half-life and decay energy.
Researchers have developed bioactive factors-imprinted scaffold vehicles to promote bone healing by improving the stability and half-life of exogenous biofactors. The vehicles were used in various forms, including rigid bone graft substitutes, soft sponge-like scaffolds, and injectable vehicles, to enhance bone repair.
IBP-CP24, a newly engineered peptide, exhibits prolonged half-life and potent anti-HIV activity, including effectiveness against drug-resistant strains. Its combination with broad neutralizing antibodies may reduce treatment costs.
Vertebrates have evolved advanced night vision due to the adaptation of ancestral rhodopsins. Early tetrapods likely developed nocturnal traits, while mammals occupied both nocturnal and crepuscular niches.
Scientists at Rensselaer Polytechnic Institute observe the longest, slowest process directly: radioactive decay of xenon-124. The XENON Collaboration's detector picked up signals from ultra-rare double-electron capture events, marking a significant advancement in knowledge about matter's fundamental characteristics.
Physicists at Rice University have reported the first direct observation of two-neutrino double electron capture for xenon 124, a process that decays into tellurium 124 with an estimated half-life of 160 trillion years. This discovery puts the half-life closer to 18 sextillion years, challenging our understanding of this isotope.
Researchers at University of Basel developed a new method to measure RNA molecule half-life, revealing most RNAs are short-lived, living less than 2 minutes. This challenges conventional methods and underlines importance of accurate measurements for cell cycle studies.
A study by Lisa White and colleagues found that parasite half-life is a key predictor of artemisinin-resistant malaria, but the current definition of resistance is inaccurate. The researchers suggest refining the definition to account for parasite load at the start of treatment.
The Weizmann Institute of Science has developed a novel, highly active interferon variant called YNSalpha8. PASylation technology extended its half-life in the body, resulting in improved protection from disease progression in a mouse model of human multiple sclerosis.
Amunix is presenting unpublished data on its XTEN half-life extension technology, which extends the half-life of biologically active molecules via chemical conjugation. The technology has been used to extend the half-life of genetically fused therapeutic proteins and peptides.
Researchers narrow down possible masses for neutrino, a tiny particle that rarely interacts with matter, using sensitive detectors buried underground. The new data suggests a neutrino cannot be more massive than about 0.140 to 0.380 electron volts.
Researchers discovered a shorter half-life of nucleus samarium-146, shrinking the assessed chronology of events in the early solar system to a shorter time span. This new value is consistent with recent dating made on a lunar rock and other chronometers.
Researchers at Argonne National Laboratory have measured the half-life of samarium-146, revealing it decays in just 68 million years, significantly shorter than previously thought. This new value patches holes in current understanding and matches recent lunar rock dating, providing insight into solar system evolution.
Researchers used the Jaguar supercomputer to simulate the interactions within carbon-14 nuclei and found that strong three-nucleon forces extend its decay. This discovery helps explain why carbon-14 is a useful tool for dating ancient objects.
Research reveals that high-strain tendons, like the Achilles tendon, repair themselves less frequently due to increased mechanical damage. This study sheds light on the increased susceptibility of certain tendons to injury during aging.
Versartis has presented positive preclinical data on its two product candidates, VRS-317 and VRS-826, which have the potential to extend half-life of drugs. The company's compounds have shown in vivo potency equal to daily hGH and sustained plasma levels without toxicity.
Versartis announces preclinical abstracts on its two product candidates VRS-859 and VRS-808, which utilize Amunix's rPEG technology to extend biologics' half-life. The compounds aim to reduce dosing frequency and side effects in type 2 diabetes and prevent nocturnal hypoglycemia in type 1 diabetes.
Researchers at Durham University found that commercial violent computer games can be used to build virtual worlds for training in fire evacuation procedures. The study showed that using game code from First Person Shooter games is quicker and more efficient than traditional virtual reality toolkits.
Researchers discovered that uridine residues are added to the 3' end of histone mRNAs, decapping and degrading them via the general mRNA decay machinery. This work represents a new mechanism regulating the half-life of specific mammalian mRNA transcripts.
A multicenter study of 770 individuals found that a once-daily Abacavir regimen achieved similar virologic responses as the traditional twice-daily dosing regimen, with 66% achieving undetectable HIV-1 RNA levels. The regimen was also found to have a similar safety profile, with minimal hypersensitivity reactions reported.
The study found that rhTSH reduced the mean effective half-life of radioiodine by 26% in patients who received it before therapy. This reduction allowed patients to clear 131I more rapidly, resulting in lower radiation levels in their blood and tissues.
A major study of over 7,000 living donor kidney transplant patients found that Neoral significantly improves three-year graft survival rates and prolongs the estimated graft half-life compared to tacrolimus. This suggests a clear advantage for Neoral in reducing the risk of transplant failure.