Articles tagged with Medical Research Facilities
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study of 290 hospital referral regions found that 53.1% experienced load imbalance due to overcapacity, with Black patients disproportionately affected. The research emphasizes the need for better coordination of patient transfers and real-time data sharing across hospitals.
CEPI and HMRI collaborate to leverage AI technology for faster vaccine development. The partnership aims to identify epitopes that stimulate the immune system, enabling swift clinical testing.
Research reveals e-cigarettes carry potential health risks, including increased blood pressure and heart rate. Long-term studies are needed to fully understand the effects of e-cigarette use on the heart and lungs.
Researchers emphasize the importance of clear causal assumptions and sensitivity analysis to evaluate results' robustness. They advocate for adopting transparent practices in conducting and reporting causal analyses, leading to better understanding of causal relationships and evidence-based decision-making.
Researchers at MIT are developing a continuous mRNA manufacturing platform to improve vaccine development and production. The pilot-scale system aims to reduce costs, increase efficiency, and facilitate collaboration in the biopharmaceutical industry.
A significant rise in caesarean sections in late labour has led to an increase in impacted fetal head (IFH) injuries, resulting in minor damage, lifelong consequences, or even death. New devices like the Tydeman tube and training approaches aim to improve management of this obstetric emergency.
Researchers at Texas A&M University found that substance use impairs cognitive flexibility by inhibiting specific neurons. Chronic cocaine or alcohol use alters the local inhibitory brain circuit, leading to decreased cognitive flexibility and increased risk of academic deficits and lower quality of life.
Researchers examine whether robots and AI can replicate the ethical concepts attributed to human nurses, including advocacy, accountability, cooperation, and caring. While AI can inform patients about medical errors and present treatment options, it questions its ability to truly understand and empathize with patients' values.
A team from the University of Ottawa has developed a comprehensive screening platform and cellular interrogation tool to facilitate novel drug discovery targeting various human diseases. The 'Tango-Trio' platform can identify small molecule modulators for orphan GPCRs, which have significant untapped therapeutic potential.
A WVU researcher is working to understand the unknowns about microorganisms growing inside pipes that bring drinking water to homes and businesses. Biofilms can be detrimental to drinking water quality, but the researcher aims to develop strategies for maintaining water quality throughout complex infrastructures.
Researchers at Korea University Medicine identified a new neuroimaging-based biomarker for MDD, the local gyrification index (LGI), which shows decreased cortical folding in patients. LGI values reflect long-drawn developmental processes and are stable markers compared to previous biomarkers.
Three University Hospitals and Case Western Reserve University research teams received $50,000 Collaborative Science Pilot Awards to explore innovative research projects. The awards aim to increase competitiveness and capacity for major external funding opportunities in key areas such as cancer, brain health and genetics.
Researchers at HKUMed have developed a novel microneedle patch that uses ultrasound-responsive antibacterial nanoparticles to effectively treat skin infections caused by P. acnes bacteria. The treatment promotes pain-free delivery and facilitates skin repair, offering a non-antibiotic approach for acne and other skin conditions.
A recent study found that GPT-3 can generate accurate information, but also produces highly persuasive disinformation. Participants struggled to distinguish between tweets created by the AI model and those written by real users.
A 12-year study by Pennington Biomedical researchers found that metabolic surgery provides better results, less regression, compared to medical or lifestyle intervention for patients with class 1 obesity. The study showed significant improvements in glycemic control and weight loss, with high rates of diabetes remission.
A team of researchers has developed a promising synthesis method for producing 6-(difluoromethyl)phenanthridines, which hold tremendous potential for drug development. The study uses aryl-substituted difluoromethylborates and radical isonitrile insertion to form phenanthridine.
The American Heart Association has launched a $20 million initiative to tackle health challenges in rural America, focusing on novel solutions to heart disease disparities. The Health Equity Research Network on Rural Health aims to explore innovative ways to address unique obstacles faced by rural communities.
Researchers aim to identify best practices for increasing viral suppression in low-income populations with HIV. They will examine state AIDS Drug Assistance Programs to understand disparities in care and outcomes.
The £72 million investment will support cutting-edge research in fluid dynamics, biological sciences, and astronomy. It aims to maintain the UK's position as a science superpower and accelerate innovation in various fields.
A preclinical study has uncovered the role of Y chromosome gene KDM5D in regulating anti-tumor immune responses and promoting metastasis in male patients with KRAS-mutated colorectal cancer. The study reveals that mutant KRAS drives upregulation of KDM5D, leading to reduced cell adhesion and immune recognition by the immune system.
Researchers developed Precious1GPT, a multimodal transformer-based approach for aging clock development and feature importance analysis. The model utilizes methylation and transcriptomic data to predict biological age and identify disease-related genes, providing a pathway for therapeutic drug discovery.
A post-hoc analysis of the ASPREE trial found that low-dose aspirin was associated with a 20% increased incidence of anemia and decline in ferritin levels in healthy older adults. The study recommends periodic monitoring of hemoglobin for patients taking aspirin.
Winship Cancer Institute has received renewal of its National Cancer Institute-designated Comprehensive Cancer Center designation, solidifying its position as Georgia's only NCI-designated Comprehensive Cancer Center. The designation recognizes Winship's strong research programs, robust shared resources, and first-rate scientists.
The American Heart Association invites researchers to compete in a data challenge to better understand how lipoprotein(a) levels impact cardiovascular disease and stroke risk. The winning project can receive a $40,000 cash prize.
A survey study found that patients with health insurance, a primary care provider, and ongoing health needs are more likely to use online patient portals. Portal users tend to have higher levels of education and live in urban areas, while non-users cite lack of awareness and technical issues as reasons for not using the platforms.
The Shape Up! Keiki research study aims to create a better way to measure and describe health from body shape, focusing on identifying obesity risks in young children. Participants aged 5 years or younger will be compensated $200 for their time.
A new study from the Stowers Institute for Medical Research reveals the placenta's polyploid cells play a vital role in supporting healthy embryonic development. The modified cell cycle controlling polyploidy is governed by the regulatory gene Myc, which supports DNA replication and prevents premature cellular aging.
A supervised hospital walking program has been shown to reduce nursing facility admissions for older adults by lowering the proportion of patients discharged to skilled nursing facilities from 13% to 8%. However, low participation rates and limited impact on length of stay or inpatient falls were noted.
Researchers developed a novel blood serum assay to diagnose neurodegenerative diseases by detecting abnormal α-synuclein. The assay, IP/RT-QuIC, can efficiently detect low concentrations of α-synuclein seeds and distinguish between Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy.
A large study of nearly 10,000 Americans with COVID-19 has uncovered the most common symptoms and potential subgroups associated with long COVID. The research team identified 12 key symptoms that distinguish those with and without long COVID, as well as a scoring system to diagnose and monitor patients.
A wearable device developed by Georgia Tech researchers detects obstructive sleep apnea and quality of sleep at home, addressing comfort, time, access, and cost issues. The patch has an 88.5% accuracy rate for sleep apnea detection and can predict the likelihood of developing the condition.
Researchers propose separating EHR time outside scheduled appointments as 'after-hours' to improve accuracy and replicability of EHR workload studies. Refining vendor-defined measures will facilitate comparative research among health systems, illuminating the link between EHR workload and provider burnout.
Researchers found that patient-guided tours empower patients to describe their own clinical experiences, increasing comfort levels and collaboration with medical teams. The approach shows promise in understanding the experiences of patients with disabilities in clinic settings.
The National Institutes of Health is enrolling 10,000 participants in a landmark precision nutrition study. The study aims to develop algorithms predicting how individuals respond to different foods and diets based on genetic, lifestyle, and environmental factors.
A study published in The Lancet Regional Health - Western Pacific found that carbapenem-resistant Acinetobacter baumannii (CRAB) contaminated the entire ICU, with samples detected on bed units, ventilators, and equipment. The researchers highlight the urgent need for targeted infection prevention and control measures to stem the global...
Researchers found that Fiocruz's partnership with AstraZeneca was crucial to the success of COVID-19 vaccine production in Brazil. The partnership demonstrated the importance of technology transfer agreements, regulatory support, and political skill. Bio-Manguinhos facility played a significant role in producing vaccines, making over 5...
The 'Low Oxygen and Weight Status' study will investigate the effects of low oxygen levels on weight loss and health outcomes in adults with obesity. Participants will be randomized to sleep in an altitude tent or normal conditions, while following a weight loss diet. The study aims to inform new strategies for improving metabolic health.
Researchers at UVA Health System have made a breakthrough discovery about the role of microglia in seizure disorders. The study suggests that enhancing microglial activity could be a promising approach to preventing and managing seizures, offering new hope for patients who don't respond to existing treatments.
The grant aims to develop accurate household food waste measurement methodologies and metrics. Innovative technologies will help create impactful interventions to minimize and eliminate food waste in the United States and globally.
A team of researchers from POSTECH and Georgia Tech developed a biohybrid 3D printed heart model with integrated sensors to monitor drug-induced cardiotoxicity. The platform enables real-time, continuous monitoring of heart contractions, facilitating the testing of acute and chronic pharmacological effects.
Scientists have found that antibodies targeting βII-spectrin on mesangial cells are the trigger for IgA nephropathy. This discovery enables blood-based diagnosis and may lead to improved treatments.
Researchers found that physical activity can prevent cancer recurrence in stage III colon cancer patients by lowering the recurrence rate within the first year of treatment. This association persisted for approximately three years after surgery, suggesting a long-term survival benefit.
Cases of Candida auris, a highly contagious fungal infection, rose drastically between 2019 and 2021, with an increase in echinocandin-resistant cases. The findings emphasize the need for improved detection and infection control practices to prevent the spread of C auris.
A team of researchers developed a transfer-tattoo-like cell sheet that can be directly applied to targeted surfaces, facilitating cutaneous wound healing and promoting skin tissue regeneration. The system leverages natural cell migration between surfaces, eliminating the need for external stimuli and detachment processes.
A recent study found that US zip codes in extreme socioeconomic disadvantage have limited access to accredited medical imaging facilities and centers of excellence. This lack of access can lead to delayed or missed diagnoses, exacerbating existing health disparities.
Researchers from Swansea University and Université Grenoble Alpes demonstrate the effectiveness of selenium nanoparticles in killing ovarian cancer cell models. The study reveals a novel biological mechanism underlying the anti-cancer effect, involving histone methylatransferases and epigenetic processes.
A new study found Black South Africans who migrated to find work reported better emotional well-being and were at lower risk for depression after the move. The research may help policymakers tailor mental health resources to underprivileged migrants and those seeking economic mobility.
A new study finds that Mexican American stroke survivors are less likely to receive intensive rehabilitation services compared to non-Hispanic white peers. Nearly one-third of all stroke survivors in the study did not receive any rehabilitation within 90 days of their stroke.
A recent study found that AI failed to pass a radiology qualifying examination, with an average accuracy of 79.5%. However, the researchers suggest that further training and revision could lead to improved results.
Columbia University's Vagelos College of Physicians and Surgeons has launched a neurodegenerative disease research center, thanks to a $50 million gift from the Carol and Gene Ludwig Family Foundation. The Center will support research on Alzheimer's disease and related disorders, with a focus on innovative treatments.
Dr. Keith Chan joins Houston Methodist to enhance chemoimmunotherapy responses in bladder cancer, while also expanding research into pancreatic and skin cancers. He will lead translational research and mentor next-generation cancer researchers.
A study published in the Journal of Dentistry found that patients with unexplained brain abscesses were three times more likely to have oral bacteria present. The researchers also discovered significantly higher counts of Streptococcus anginosus, a bacterium linked to dental abscesses and infections in internal organs.
A recent study found that MRI-guided adaptive radiation therapy, also known as SMART, has shown promising safety and patient outcomes data for treating locally advanced and borderline resectable pancreatic cancer. The study, led by Henry Ford Health, reported no incidence of acute grade 3 or higher gastrointestinal toxicity, with preli...
A study using mRNA and miRNA expression profiles identified molecular signatures that can differentiate muscle invasive bladder cancer patients who respond to neoadjuvant chemotherapy from those who do not. The research found distinct gene pathways and subtypes associated with response, which may lead to more effective treatment delivery.
A large contact tracing investigation found no secondary cases of monkeypox, informing estimates of exposure risk and postexposure prophylaxis recommendations. The framework's ease of application and cross-setting use has important applications for future infection prevention efforts.
The University of Missouri has earned an $8 million grant from the National Institutes of Health to expand its National Swine Resource and Research Center. The center will support research using genetically modified pigs to study human diseases, with a focus on therapies that can be translated from pig models to humans.
A Northwestern University study found that physicians may deny care to people with disabilities due to bias and lack of knowledge about accommodations. The study's results suggest a need for changes in medical education and approach to improve accessibility for patients with disabilities.
A $1 million NIH grant will help MU researchers analyze the effectiveness of a HIPAA-secure text messaging platform in nursing homes. The study aims to improve quality of care and prevent costly hospital transfers by speeding up decision-making.
Research from UVA Cancer Center finds that an unhealthy gut microbiome can trigger changes in normal breast tissue, facilitating cancer's spread to other parts of the body. The study suggests that targeting the gut-mast cell relationship could help prevent breast cancer recurrence and metastasis.
A team of neuroscientists at the University of Pittsburgh and Carnegie Mellon University aim to create an ultra-high resolution molecular atlas of the brain, enabling precise gene delivery to specific cell types. This project has the potential to revolutionize treatment of fatal brain diseases such as Alzheimer's and Parkinson's.