Articles tagged with Medical Research Facilities
Researchers at the University of Virginia Health System have discovered how Lactobacillus, a bacterium found in fermented foods and yogurt, influences mood disorders. The findings suggest that maintaining a healthy level of Lactobacillus may help prevent depression and anxiety by regulating immune response to stress.
A new study found that simulated high altitude exposure can increase haemoglobin levels in older patients, potentially benefiting their physical health before surgery. The research suggests that 'altitude prehabilitation' could be a useful approach to improve fitness and reduce complications in patients at risk.
Researchers aim to determine optimal duration and intensity of behavioral interventions for childhood obesity among rural and minority children. The five-year study, funded by the Patient-Centered Outcomes Research Institute, will enroll 900 parent-child pairs and compare different 'dosing' combinations of face-to-face intervention time.
Researchers found high levels of a repair protein in the brains of former NFL athletes up to 12 years after they stopped playing, indicating persistent brain inflammation and long-term cognitive problems. The study suggests that repeated collision sports like football may have a direct link to long-term inflammation in the brain.
The American Heart Association and Neurocritical Care Society emphasize the need for improved critical care management of patients after cardiac arrest. The consensus statement highlights gaps in knowledge, particularly in areas like neurological, cardiac, and gastrointestinal care.
Researchers found that practice interventions for improving integrated behavioral health (IBH) activities had a minimal impact on patient outcomes. However, practices that completed the intervention and those with higher IBH levels showed improved patient outcomes.
An international group of researchers developed a Consensus Reporting Items for Studies in Primary Care (CRISP) Checklist, outlining 24 items to improve the quality and consistency of primary care research. The checklist addresses various aspects of research, including study design, data collection, and implementation of findings.
Researchers predict that vampire bats will expand their locations in search of more stable climates, potentially linked to a spillover of rabies. The team's work aims to identify and track the bats by traveling to Colombia to contain the spread.
Researchers developed a practice facilitation program to support family physicians in identifying unvaccinated patients and addressing vaccine hesitancy. The intervention provided resources such as scripts and medical student volunteers to work as physician-delegates, resulting in improved vaccination rates.
A new study by the University of Plymouth reveals that chlorine disinfectants used in hospitals are no more effective at killing off hospital superbugs than water. The research highlights the need for alternative strategies to tackle Clostridioides difficile, which causes diarrhoea, colitis and other bowel complications globally.
A new pill-sized device has been developed to monitor vital signs like breathing and heart rate from inside humans. The device, known as the VM Pill, was tested in a clinical trial and showed accurate results in detecting breathing stops and monitoring respiration rates with high accuracy.
Researchers found that tumor-resident T-cell receptor sequences showed high complementarity with the cancer testis antigen DDX53, suggesting an immune response that selects for DDX53-negative cells. This association was correlated with worse disease-free survival rates, highlighting a potential early esophageal cancer antigen.
A UCLA study found that hospitals with high patient diversity are less likely to offer core cancer services, including hospice care, chemotherapy, and robotic surgery. The lack of these resources can impact treatment quality and outcomes for patients diagnosed with cancer.
Researchers at Weill Cornell Medicine found that partnering with local religious leaders increased the adoption of family planning methods in Tanzania. The approach, which involves workshops and training for faith leaders, led to a 19% rise in contraceptive uptake in communities where religious leaders participated.
A new wearable ultrasound patch can accurately image organs within the body without traditional ultrasound equipment, enabling earlier detection of cancers deep within the body. The patch is designed to measure bladder volume, providing valuable insights into kidney health and wellness.
A 20% reduction in major adverse cardiovascular events has been observed for patients with obesity but no history of diabetes taking semaglutide. This study marks a significant milestone, demonstrating the cardiovascular benefits of semaglutide beyond its weight loss effects.
The UTHealth Houston Institute for Implementation Science has received a five-year, $5 million grant from the National Cancer Institute to support research and training in implementation science. Researchers will focus on improving cancer control efforts in Mexico and Latin America.
Researchers have developed a new self-assembling nanosheet that can create functional and sustainable nanomaterials for various applications. The material is recyclable and can extend the shelf life of consumer products, enabling a sustainable manufacturing approach.
Researchers introduced a cost-effective solution to correct tilt and curvature errors in two-photon polymerization 3D printing. The method uses Fourier scatterometry, which offers lower uncertainties than traditional methods, resulting in improved image quality and precision.
Researchers at UTSA have discovered a novel strategy to inhibit the spread and infection of Vibrio cholerae, the bacteria responsible for cholera. They identified a peptide-binding domain that can disrupt the virulence of V. cholerae, preventing intestinal colonization and biofilm formation.
A study found that Black and Hispanic cardiac arrest survivors are less likely to be treated at high-performing hospitals, leading to lower survival rates and poorer neurological outcomes. The research analyzed health records from the Cardiac Arrest Registry to Enhance Survival and found disparities in hospital quality measures.
A study found that Black and Hispanic cardiac arrest survivors were less likely to be treated at top-performing hospitals. The analysis of health records from the Cardiac Arrest Registry to Enhance Survival (CARES) revealed significant disparities in hospital quality measures based on race/ethnicity.
A study found that gastrointestinal and sleep issues may be connected to self-injury and aggression in adolescents diagnosed with profound autism. The researchers discovered a possible connection between these health issues and future challenging behaviors, predicting next-day behavior with over 80% accuracy.
Researchers from Incheon National University create gelatin patches that generate molecular oxygen to accelerate wound healing. The new hydrogels demonstrate improved coagulation, blood closure, and neovascularization in both in vitro and in vivo experiments.
The new department will expand and improve isotope research and production to meet the nation's growing need for critical isotopes. Cathy Cutler plans to leverage the Lab's nuclear physics accelerator infrastructure to develop novel isotopes and applications.
A small clinical trial led by the University of Houston demonstrates Riluzole's effectiveness in improving functionality in people with acute spinal cord injuries. The study used an SCI-specific biomarker to show how Riluzole reduces neuron cell damage and improves motor abilities.
Researchers from Texas A&M University's Department of Geography and collaborating departments aim to improve understanding of how environmental hazards influence human health outcomes. The project, 'Climate-LEAD,' will create robust models using localized data to inform decision-making in vulnerable communities.
Researchers develop device capturing airborne droplets and aerosols while allowing light and sound transmission. The innovation offers a sustainable solution to preventing airborne infection without disrupting economic activities or daily face-to-face interactions.
Scientists have developed a technique to restore the function of human-derived GPCR proteins in yeast cells, which could accelerate research and lead to more effective treatments. The approach, using error-prone polymerase chain reaction, introduces random mutations that enhance protein stability and function.
A new yeast-based screening method has been developed to unravel how plants synthesize medicinal compounds, identifying key enzymes in a kratom tree. The method complements traditional approaches by capturing protein-protein interactions between plant enzymes.
Clinical quality registries collect and store health information to optimize healthcare and management in ICUs, providing valuable data for scientific research and epidemiological maps. The review highlights the role of CQRs in benchmarking strategies between hospitals and improving resource management.
Researchers develop a new approach to strengthen the immune system to fight viruses, using macrophage colony-stimulating factor (M-CSF) as a treatment. The study shows that M-CSF boosts production of white blood cells, protecting immunocompromised patients from CMV infection.
A recent NIH grant will support research into the genetic factors contributing to cardiac arrhythmia, a condition affecting millions of Americans. The study aims to identify specific genes linked to arrhythmia risk and develop novel therapeutic approaches.
A new study published in the Journal of the American Heart Association found that chronic kidney disease may increase the risk of sudden cardiac arrest among Hispanic/Latino adults. Heavy drinking and preexisting heart disease were also linked to an increased risk of sudden cardiac arrest.
The Keck School of Medicine of USC has received a $2 million grant from the California Institute of Regenerative Medicine to further enhance its cutting-edge cGMP Laboratory. The funding will support the adoption of advanced technologies, including an electronic quality management system and optimized cell therapy manufacturing processes.
Researchers found that administering precursors of Elovanoids improved neurological deficit in an experimental model of ischemic stroke. The study identified a cascade of gene responses and sheds light on potential new therapeutic avenues for treating ischemic strokes.
A new biomimetic chip has been developed to simulate the human gastric mucosa, combining organoid and organ-on-a-chip technologies. The biochip replicates mechanical stimulation and cell-to-cell interactions, mimicking key features of the human stomach's defense mechanisms.
A new editorial paper highlights the importance of including older patients in lung cancer clinical trials, where they are often undertreated due to age-related factors. The paper emphasizes the need for increased collaboration among stakeholders to enhance enrollment and retention of older cancer patients.
A small molecule drug improved the fitness of hematopoietic stem cells used in cell transplants, potentially enhancing the success of procedures like ex vivo gene therapy. The study found that targeting extracellular vesicles relieved stress on cells outside the body, improving their performance when transplanted back in.
The University of Rochester is awarded funding to design and prototype the EP-OPAL facility, which will enable the creation of the highest-power laser system in the world. The facility aims to reestablish US leadership in high-peak-power lasers and fundamental science.
A study using engineered mice found that BA.5, a contagious omicron subvariant, replicates rapidly early during infection, causing significant weight loss and high levels of inflammatory cells and cytokines in lungs.
A qualitative study found that staff turnover, staffing shortages, and time constraints are major barriers to participation in quality improvement projects. The authors recommend policy makers provide direct support for primary care to alleviate burnout and address these challenges.
Primary care teams struggle to implement quality improvement efforts due to staff turnover, staffing shortages, and time constraints exacerbated by the COVID-19 pandemic. Researchers recommend direct support for primary care to alleviate burnout and improve participation in quality improvement projects.
Researchers developed a scoring system analyzing income, education, geographical location, access to care, and other factors to identify patients at increased risk of poor outcomes. The study found significant socioeconomic disadvantage associated with a 21% decrease in textbook outcomes and a 32% decrease in overall survival.
A team of UC researchers, led by Ashley Kubley, have received a $2.5 million state grant to continue research on improving firefighter protective gear. The project aims to develop a firefighter jacket liner that brings down body temperature through advanced cooling technology and protects against external hazards.
Researchers at West Virginia University have developed a technology that can capture carbon dioxide from the air of buildings and use it to produce methanol, a common chemical with numerous applications. The process is expected to increase the sustainable supply of methanol while removing greenhouse gases from the atmosphere.
The Louisiana Clinical & Translational Science Center has received a $1.3 million NIH grant to support the creation of a network of data warehouses for healthcare providers and researchers in Baton Rouge. The project aims to enhance research capacity, address health care disparities, and improve patient engagement.
A new study suggests that transcranial ultrasound stimulation can be used to change specific types of activity within the brain, paving the way for targeted treatments of mental health conditions. The research found that TUS induced significant changes in GABA concentration and altered communication between brain regions.
Researchers have successfully performed robotic bladder transplantation in human cadaver models and beating-heart donors. The technique aims to reduce surgical times and improve outcomes for patients with terminal bladder conditions.
Research highlights ways to blend caring profession into virtual landscape, focusing on pre-visit, visit, and post-visit phases. Key findings emphasize active listening, reflective listening, and maintaining professional appearance for effective communication.
Researchers at UNIST developed a microfluidic system to process blood into artificial tissue scaffolds for vascular regeneration. Autologous blood-based implants demonstrated superior wound closure rates, increased epidermis thickness, and enhanced collagen deposition in rodent skin wounds.
Researchers developed a photoelectrochemical technique to precisely tune the lasing wavelength of microdisk lasers with subnanometric accuracy. The new approach facilitates the fabrication of micro- and nano-laser batches with precise emission wavelengths.
A study by Pennington Biomedical Research Center and Woman's Hospital found that pregnant women in Louisiana were more likely to exceed recommended weight gain levels during the pandemic, with a 3-7% increase. This rise in non-optimal gestational weight gain may have long-term impacts on maternal and infant health.
A recent MU study found that health and healthcare organizations are increasingly offering basic social services, such as transportation, housing, food, and mental health support, to address disparities in health outcomes. The research team explored innovative solutions implemented by care coordinators and social services to help overc...
Researchers at National Korea Maritime and Ocean University developed a close contact identification algorithm that outperforms conventional clustering algorithms. The algorithm enables accurate tracking and physical isolation of individuals in ship environments, contributing to the health and safety of passengers.
University of Louisville researchers have received a five-year, $11.7 million National Institutes of Health grant to investigate the connection between microorganisms and disease. The study will focus on various chronic conditions, including Alzheimer's disease, heart disease, diabetes, periodontitis, and colorectal cancer.
Researchers at the University of Manchester are enhancing bioprinting technology to create new skin, bone, and tissue for transplantation in space. The project aims to protect astronauts' health from diseases like osteoporosis caused by microgravity exposure.
A recent study by Pennington Biomedical Research Center identifies GDF15 as a protein that acts as a cellular signal to enhance insulin secretion. High-intensity exercise training in patients with type 2 diabetes was found to have elevated levels of GDF15, associated with improved glycemic control.
A new matching system enabled by Boston College economists facilitates the world's first four-way liver exchange and a cascade of additional matches. The system increases the number of transplants that can be matched among a larger group of participants, expanding capacity beyond traditional two-way exchanges.
Researchers at Binghamton University have developed genetically engineered nanovesicles that can target cancer cells more effectively than traditional chemotherapy. These nanocarriers can deliver therapeutic agents directly to the interior of cancer cells, reducing harm to healthy cells and increasing treatment efficacy.