The study classified duplicate pairs of genes involved in yeast metabolism into four functional categories: back-up, subfunctionalization, regulation, and gene dosage. These mechanisms play a substantial role in maintaining duplicate genes in the genome.
Researchers identify 64 genes used to separate breast cancer patients with good and poor prognoses. The technique of DNA microarray analysis could help predict patient response to adjuvant therapy, avoiding unnecessary treatments.
Researchers have discovered a novel T helper cell type, called THi cells, that produce the potent cytokine IL-17 and are responsible for initiating chronic inflammation and autoimmunity. The study's findings suggest that targeting these cells could lead to effective treatments for inflammatory diseases such as arthritis and asthma.
Researchers identified genetic signatures that predicted patient prognosis and response to treatment, outperforming existing clinical markers. The technique of DNA microarray analysis holds promise for developing new prediction methods, sparing patients from unnecessary treatments.
A synthetic pheromone has been found to effectively control Great Lakes lamprey populations by attracting them to traps and sterilizing males. The pheromone, PADS, was isolated after 15 years of research and is expected to be environmentally friendly and less expensive than current methods.
Researchers at Thomas Jefferson University identified a genetic mutation in the Stratifin gene that causes abnormal skin development and cancer in mice. The study found that mice with the mutation developed severe skin defects, including cyclical hair loss and skin cancer late in life.
A recent study has found that patients who are obese at age 40 and experience rapid weight gain have a higher risk of prostate cancer recurrence. The research, published by the American Association for Cancer Research, suggests that men who gained an average of three and a half pounds per year are more likely to experience biochemical ...
Experts from the American Institute of Biological Sciences assess dredge-and-fill programs to protect coastlines, highlighting flaws in current practices. The studies aim to identify areas for improvement and promote more effective ecological monitoring.
A study of 526 prostate cancer patients suggests that a man's body mass at different ages and adult weight gain can predict the risk of progression after surgery. Researchers found that obese men and those who gained weight quickly experienced biochemical failure more often.
The Phase II study showed that FTY720 reduced annualized relapse rates by at least 50% during the first six months and maintained this rate for an additional six-month extension. Patients who switched to FTY720 after six months experienced a reduction of at least 70% in their annualized relapse rate compared to placebo.
Researchers studied over 450 women with family histories of breast cancer to understand their soy product use. Key findings include that nearly half of the women consume soy products and believe they may reduce cancer risk, while others cite taste preferences or difficulties in preparation.