Researchers at Duke University have successfully grown a three-dimensional 'patch' of heart muscle cells using embryonic stem cells and a novel mold design. The patch exhibited the ability to contract and conduct electrical impulses, crucial attributes of native heart muscle cells.
A recent study by researchers at the University of Wisconsin-Madison and IT University in Copenhagen found that 94% of respondents violate computer authentication best practices, with novice users being more likely to do so. The study emphasizes the need for a better balance between human limitations and security measures.
Eric Boerwinkle has received a $26 million federal stimulus grant to identify genetic factors affecting heart, lung and blood diseases. The project will analyze the DNA of approximately 40,000 individuals to pinpoint genetic variants affecting disease risk, aiding in disease detection and treatment selection.
A new study finds that women with a deleterious BRCA gene mutation are diagnosed with breast cancer six years earlier than their relatives who also had the disease and/or ovarian cancer. The findings could impact how women at highest risk for breast cancer are counseled and screened in the future.
A new study reveals that Africa's big cats, including leopards, tend to avoid croplands and favor specific habitats. This research provides valuable insights into the spatial distribution of carnivores in Tanzania, shedding light on the impact of habitat conversion and climate change.
A new study by University of Southampton researchers found that sea levels have been rising across the south coast of England, substantially increasing the risk of flooding during storms. The team's data set covers over 150 years of historic sea level change, revealing a steady rise of 1.2-2.2 mm per year.
The hospital received a total of 69 grants across multiple departments, focusing on cancer research, cardiovascular diseases, and sleep apnea management. BIDMC scientists will investigate innovative methods to heal broken bones, develop new cancer therapies, and improve sleep health.
The University of Adelaide's Professor Konrad Jamrozik has spent 30 years campaigning against smoking and helping smokers quit. He has contributed significantly to tobacco control through his research, clinical trials, and advocacy.
Researchers found that common herbicides and lipid-lowering drugs inhibit the T1R3 receptor in human tissues, affecting glucose homeostasis and energy metabolism. The study's findings highlight the importance of testing chemicals on human tissues to understand potential health effects.
A new technique called Hyper-SAGE amplifies MRI signals by up to 10,000 times, allowing for the detection of low concentrations of cancers and other clinical targets. This breakthrough enhances the sensitivity of Magnetic Resonance Imaging (MRI) technology.
The Translational Genomics Research Institute has been awarded $691,930 to develop brain tumor research using in silico simulations. The project will utilize comprehensive genomic data involving 40 brain tumor models and 20 proven types of targeted therapies.
Researchers at the University of York have identified an enzyme called XplA that can break down royal demolition explosive (RDX) in the soil. The discovery provides significant insights into biological function and could lead to more efficient cleanup methods for RDX pollution.
Researchers at Ludwig-Maximilians-Universität München have detailed the process of RNA polymerase II initiating gene transcription. The complex recognizes signals in the DNA sequence and uses TFIIB to bind to the TATA box, producing a sharp kink in the DNA.
A large study found that individuals following a Mediterranean diet, rich in fruits, vegetables, and whole grains, were less likely to develop depression. The diet's high intake of monounsaturated fatty acids from olive oil may be protective against depressive symptoms.
A UCLA-led study confirms Pallas, the second-largest asteroid, is a protoplanet due to its unique shape and color variation. The research reveals a dynamic surface with areas of dark and light, indicating internal changes, similar to those found on planets.
The National Institutes of Health is launching a clinical trial to find the ideal dose of the 2009 H1N1 influenza vaccine for individuals with severe asthma. The study aims to assess the immune response and safety of two different doses of the vaccine in participants with mild, moderate, or severe asthma.
Researchers have found that a standard treatment protocol can improve survival rates nearly two-fold for pediatric patients with choroid plexus tumors. The study suggests that chemotherapy and radiation can be effective in reducing mortality rates, contradicting previous research on surgical resection.
A Michigan State University researcher found that providing small classes for at least several consecutive grades starting in early elementary school improves test scores and narrows the achievement gap with high-achievers. Low-achieving students benefited the most from small classes, likely due to increased attention from teachers.
A study published in the Journal of the American College of Cardiology found that patients who received refurbished pacemakers donated from Detroit area funeral homes survived without complications. The pacemakers functioned normally at six months, with no device complications reported.
A study of over 2,000 women with stage II and III breast cancer found that achieving pathological complete response after treatment was not related to race. Despite racial disparities in breast cancer incidence and mortality rates, Hispanic women had better outcomes than white women.
A recent study published in Molecular Cell reveals that the KEAP1 tumor suppressor binds to and degrades the cancer-promoting protein IKKß, which is involved in several types of cancer. The research suggests that underexpression of KEAP1 is associated with poor survival rates among breast cancer patients.
Intracellular pathogens like Chlamydia and Legionella exploit host cell biology to escape destruction. Researchers found that SNARE-like proteins expressed by the bacteria inhibit membrane fusion with lysosomes, allowing them to remain in cells.
Researchers found no significant difference in visual outcomes between Bevacizumab and Ranibizumab treatments for age-related macular degeneration after 6 months. The study suggests that both drugs are effective, with Bevacizumab being a more affordable option.
A new study published in the Journal of American College of Surgeons found that establishing an acute care surgery service can provide more efficient emergency care. The service, staffed by critical care surgeons and surgical residents, reduced wait times for urgent procedures from 55.4% to 70% after implementation.
A new study found that elevated levels of Müllerian inhibiting substance in women may increase their risk for breast cancer. Researchers discovered an association between higher MIS serum concentrations and increased breast cancer risk in a population of participants.
Expedition 322 collected sedimentary and basement rock samples from the Shikoku Basin, shedding light on the generation of large earthquakes. The study of petrological, geotechnical, frictional, and hydrogeological properties of these rocks is crucial for understanding rupture dynamics in the seismogenic zone.
Researchers have identified a receptor on the tongue that is specifically activated by glutamate, a non-essential amino acid found in many foods. This discovery sheds new light on the umami taste and challenges existing perceptions of MSG's safety.
Therapeutic hypothermia, a medical treatment lowering body temperature to reduce tissue damage, will be published in an online open-access journal starting February 2010. The journal aims to advance understanding and application of this therapy in cardiology and neurotrauma.
Researchers have developed a reliable way for doctors to filter MEDLINE for relevant kidney patient information, improving treatment and outcomes. The new tool has high performance, exceeding 97% sensitivity and specificity, making it available for all healthcare professionals.
Researchers at the University of California, San Diego, have developed a new high-throughput cellular array technology that can identify the biological components leading to or alleviating liver disease. By controlling the environment surrounding star-shaped liver cells, they found critical proteins regulating HSC activation.
The National Institute of Allergy and Infectious Diseases (NIAID) is conducting clinical trials to test the safety and efficacy of the 2009 H1N1 influenza vaccine in HIV-infected pregnant women and children, youth. The trials aim to determine whether higher doses of the vaccine can elicit a protective immune response in these populations.
A new study found significant socioeconomic disparities in the use of breast-conserving surgery (BCS) for older women with nonmetastatic invasive breast cancer. BCS was more widely used in younger patients, areas with high education levels, and metropolitan regions.
Dr. Ashley, director of the Samuel Simmonds Memorial Hospital Dental Clinic, was recognized for her work to improve oral health through training programs and onsite dental care at local schools. Her efforts have transformed the oral health of an entire community, reducing tooth extractions among children.
A new species of mammal, Maotherium asiaticus, has been discovered in China, providing insight into the evolution of the mammalian middle ear. The fossil's ear structure shows a unique connection to the lower jaw, similar to embryonic mammals and pre-mammalian ancestors.
The human genome is organized into two separate compartments, with active genes separated from inactive DNA. The fractal globule architecture enables cells to pack DNA densely while avoiding knots, allowing for efficient gene expression and replication.
A UBC-led study finds that climate change will lead to major shifts in ocean fisheries productivity, affecting global food supply. Tropical regions are expected to see significant declines in catch potential, with Indonesia, US, Chile, and China among the hardest hit.
Researchers from Massachusetts General Hospital are leading teams to develop stem-cell-based models of cardiovascular and blood disorders. The NHLBI grants will support the development of regenerative therapies for heart failure and other disorders.
Researchers at Virginia Tech's Marion duPont Scott Equine Medical Center are studying the best ways to treat lameness in horses through tendon and ligament repair. Dr. Jennifer Barrett is investigating regenerative medicine techniques, including stem cell therapy, to regenerate damaged tendons and cartilage.
Researchers are using NASA's DC-8 plane, equipped with laser mapping instruments and other equipment, to study changes in Antarctica's sea ice, glaciers, and ice sheets. The data collected will help scientists better understand how these changes contribute to future sea level rise.
Satira Streeter, a D.C. psychologist, received the Community Health Leaders Award for delivering culturally relevant mental health services to Anacostia's economically challenged communities. She founded Ascensions Community Services to provide free comprehensive services to disadvantaged children and families.
Researchers at NC State University have received a $1.4 million grant to create an unprecedented cyber infrastructure for multi-agency collaboration in crime scene investigations (CSI). The platform, called IC-CRIME, will employ 3D laser scanning technologies and game engines to virtually reconstruct and preserve crime scenes.
Tropical Storm Henri has weakened to a depression due to battering winds and strong southwesterly shear. The National Hurricane Center confirmed the wind speed using NASA's QuikScat satellite imagery, with minimum central pressure near 1010 millibars.
The Primary Immune Deficiency Treatment Consortium will focus on three severe immune disorders: SCID, WAS, and CGD. Researchers will study patients who have already received treatment and develop new clinical trials to better understand these disorders and improve treatment outcomes.
Premature aging of the immune system has been linked to amyotrophic lateral sclerosis (ALS), according to research. Studies found that patients with ALS have reduced CD4+ T cells and thymic malfunction, contributing to disease progression.
A new gene data tool has achieved greater accuracy than conventional methods in assessing individual risk for type 1 diabetes. By analyzing a large set of gene markers, the tool identifies a large ensemble of genes that interact together to predict disease risk.
The EPA has awarded 42 grants to teams of college and university students to design sustainable technologies addressing various environmental challenges. The winners will be selected based on their project designs and may receive additional funding for implementation or marketplace development.
Claudia Stravato, a Texas women's health activist, is one of 10 Americans chosen to receive the 2009 Community Health Leaders Award. She will be honored for her work in providing access to primary care for low-income and uninsured families.
Aging immune systems in elderly cancer patients are less efficient and require customized treatments. Researchers aim to understand intrinsic defects in the old immune system to stimulate antitumor responses.
The department has been awarded four NSF grants over $1 million for their research in Cognitive Radio, Wireless Communications, and Network Security. Researchers aim to advance technology with a focus on increasing contribution to CR advancement.
Researchers at Stanford University School of Medicine have identified a key molecular player in guiding synapse formation in the brain, advancing understanding of brain development and potential approaches to countering brain disorders. The study also pinpoints the biochemical mechanism by which anti-seizure drug gabapentin works.
A gluten-free diet can rapidly increase bone mineral density in children with celiac disease, leading to complete recovery of bone mineralization. Early diagnosis and a strict gluten-free diet are critical in preventing complications such as reduced bone mineral density and osteoporosis.
Frances Stout, a retired registered nurse, received the 2009 Community Health Leaders Award for establishing the first skilled nursing facility for elderly Native Americans. Her work also led to the creation of an elder care consortium addressing issues like transportation and housing.
Researchers identified a genetic defect that selectively affects white blood cell production, potentially predisposing individuals to inflammatory bowel disease. The study's findings may provide insight into why IBD develops and help inform future treatment strategies.
The National Institute of Allergy and Infectious Diseases (NIAID) has awarded contracts to discover novel vaccine adjuvants. The goal is to enhance the immune response and extend vaccine supply. Researchers will test new compounds in animal models and human cells.
The UK is launching seven new research projects to combat obesity and heart disease, using a combination of public and private sector funding. Researchers will explore the role of probiotics, polyphenols, and cognition in diet-related health issues.
Rajiv Kumar, a medical student from Rhode Island, has been awarded the Community Health Leaders Award for his work to reduce obesity among Rhode Islanders. Over 35,000 participants have taken part in his Shape Up RI program, losing thousands of pounds and walking millions of miles.
A new research institute dedicated to the Bronze Age will be established at La Bastida archaeological site in Murcia, Spain. The project aims to shed light on European prehistory and cultural heritage through systematic research and scientific analysis.
The study finds that Archaeopteryx grew slowly, taking 970 days to mature, similar to dinosaurs, and its bone growth rate was three times slower than living birds. This challenges the common perception of Archaeopteryx as a bird-like creature.
Excess weight increases severity of oxygen desaturation in individuals with sleep-disordered breathing during and after apneas and hypopneas. BMI predicts degree of oxygen depletion associated with SDB events.
A team of researchers developed a technique to replicate biological structures on a nano scale, creating free-standing replicas of fragile, laminar, chitinous biotemplates. The resulting biomaterial could be used for optically active structures, such as optical diffusers for solar panels and devices with light-emitting properties.