A study of 827 US adults found that the average daily sodium intake was 3,662 milligrams, exceeding the recommended limit of 2,300mg. Potassium levels were also lower than adequate, with women and blacks having the lowest levels.
A new study by Intermountain Medical Center Heart Institute found that two different blood clot prevention medications are just as safe and effective for patients undergoing percutaneous coronary intervention. The risk of major bleeding after 30 days was low and not significantly different between the two treatment methods.
A 10-year precision trial involving 24,081 patients in 13 countries investigated the cardiovascular safety of widely used nonsteroidal anti-inflammatory drugs and COX-2-specific inhibitors. The trial found that celecoxib shares similar cardiovascular toxicity with rofecoxib, leading to increased nuance in analgesic recommendations for ...
A study of nearly 2,400 elderly heart attack survivors found that only 9.8% filled prescription medications for smoking cessation within 90 days after discharge. Factors such as age and previous heart procedures made it less likely for patients to use these medications.
A multicenter trial found that 13 out of 36 advanced heart failure patients treated with LVAD and intensive drug therapy recovered enough heart function to have the device removed. The study suggests that these devices can be used to reverse heart failure, especially when combined with drug therapy.
Researchers studied nearly 3,000 black participants in the Jackson Heart study, who reported their smoking status. The study found that those smoking over a pack a day had a 62% higher risk of developing diabetes compared to others.
Children born via Cesarean section may be more likely to become overweight or obese, with a 40% greater odds of this outcome compared to those born vaginally. The association is strongest among mothers who are already obese, suggesting that vaginal delivery may help mitigate the risk.
Research findings suggest that gut microbiomes of patients with antiphospholipid syndrome show higher levels of phospholipid-producing bacteria, pointing to microbes as a trigger for the disease. The study identified Slackia bacteria as a promising candidate, which can produce phospholipids including cardiolipin.
New research findings suggest that men and women have different post-surgical outcomes after total hip arthroplasty. Women who had improved functional recovery showed more abductor strength improvement and better gait function during walking. Tailoring rehabilitation to each sex may help patients achieve better outcomes.
A study presented at the American Heart Association's Scientific Sessions found that black and Hispanic children are more likely to receive compressions-only CPR, but conventional CPR leads to better survival rates. Conventional CPR also improves brain function and discharge outcomes in infants.
Studies in the US and Denmark show that older adults are undertrained in CPR, with only 18% reporting current training. Higher education level and household income are linked to increased likelihood of CPR training, but there is a steep drop-off after age 50. The elderly often cite lack of knowledge and fear as barriers to performing CPR.
A new training model improved CPR skills among hospital staff by integrating low-dose-high frequency psychomotor simulation into their daily duties. Quarterly simulations resulted in significant improvements in chest compression fraction and overall clinical outcomes, leading to a 14% increase in effective compressions.
Researchers found that patients treated with rituximab as their first biologic had a lower mortality risk compared to those treated with TNFi. The study included 353 patients with RA-ILD and analyzed five-year mortality rates, with RTX-treated patients showing numerically lower but not statistically significant risks.
Research finds elevated myocardial inflammation in RA patients, with treatment showing potential to improve inflammation levels. Studies use advanced imaging techniques to detect and quantify heart inflammation, suggesting a link between joint and heart inflammation.
Researchers found a significant interaction between TNF-inhibitors and NSAIDs, with patients experiencing a 70% reduction in radiographic progression when used together. The study suggests that combining these therapies may be especially helpful for patients at higher risk of disease progression.
Research shows that many patients with RA, spondyloarthritis, and other inflammatory joint diseases are not receiving adequate CVD-preventive medications, despite being at high risk. Only half of those who start treatment achieve their goals, highlighting a significant need for improvement in CVD prevention.
Researchers identified three gene expression signatures that can help rheumatologists predict which patients are more likely to respond to certain therapies. The findings could lead to higher response rates and reduced likelihood of ineffective treatment, ultimately improving patient care.
A study of 564 patients found that women with long-term axial spondyloarthropathy are at higher risk for extra-articular manifestations, including uveitis, which is significantly more prevalent in women (46.7%) and those in late disease stages. IBD prevalence was also higher in women (16.5%), particularly those with elevated CRP levels.
Research suggests that RA patients who receive combined care from primary-care physicians and rheumatologists are more likely to be screened for hyperlipidemia. This study found that 47% of patients seeing both a PCP and rheumatologist were screened, compared to 42% of those seeing only a PCP.
A study of 9,362 surgeries on 5,544 RA patients found that continuing DMARDs prior to surgery does not increase post-operative infection risk. Researchers recommend considering medication continuation during the perioperative period to maintain better control over RA and reduce complications.
A study found that prior statin use was associated with higher survival rates after out-of-hospital cardiac arrest. Patients with Type 2 diabetes showed the most significant improvement in survival rate. Statins were linked to increased survival to hospital discharge and beyond a year after the event.
The U.S. adult rheumatology workforce is projected to decline by 31% by 2030 due to an aging workforce and insufficient graduate medical education funding. To address this gap, researchers suggest creating financial incentives for medical students and residents to pursue rheumatology training.
A retrospective cohort study found that chronic kidney disease patients who achieve target urate levels show improvement in kidney function. The study suggests that urate-lowering therapy may help stabilize or improve kidney function in patients with significantly elevated serum uric acid and moderate kidney failure.
A study of over 3,900 US children who suffered cardiac arrest outside a hospital found that those receiving bystander CPR had better survival rates and neurological outcomes. Racial disparities in CPR provision were also noted, highlighting the need for education interventions to improve minority community access.
Researchers found that people with RA have double the risk of CV events as those in the general population, rates similar to those with type-2 diabetes. Chronic inflammation in RA contributes independently to cardiovascular risks for these patients.
A multicomponent behavioral intervention delivered by lay health workers significantly reduced anxiety and depression in adults with high levels of psychological distress. The study found improvements across all dimensions, including trauma-related symptoms and functioning.
A Mayo Clinic study found that type 1 interferon beta levels are associated with poor response to tumor necrosis factor inhibitors in rheumatoid arthritis patients. This discovery may lead to more personalized treatment approaches based on individual patient biology.
Researchers found distinct monocyte gene expression signatures in RA patients with different responses to anti-TNF therapy, potentially leading to personalized treatment approaches.
New research from the American College of Rheumatology finds that most people with knee osteoarthritis (OA) meet the minimum physical function level necessary to walk at least 6,000 steps a day. This suggests that many individuals with OA can adopt physically active lifestyles and achieve significant health benefits.
A survey found that older Americans, those with lower education levels and household incomes, are less likely to receive CPR training. This lack of training can lead to a higher risk of sudden cardiac arrest, as bystanders may not know how to intervene in an emergency situation.
Quality of care varies significantly among rheumatology practices, with the largest gaps seen in osteoporosis and gout care, and some practices consistently performing well across measures. The study highlights the need for improvement in preventive care and counseling, and RISE provides a tool for guiding quality-improvement efforts.
New research finds that African-Americans, Asians, and those with a high school education or less experience significant delays in receiving lupus diagnosis and treatment. The study highlights the need for targeted solutions to address these disparities in access to specialty care.
Research finds that tumor necrosis factor inhibitors used to treat juvenile idiopathic arthritis do not increase the risk of malignancy. The study, which analyzed data from over 27,000 children with JIA, concluded that TNFi are not associated with a significantly increased risk of incident malignancy.
Research found no association between allopurinol use and increased risk of chronic kidney disease (CKD) Stage 3 or higher in gout patients with normal kidney function. Allopurinol may be beneficial for preventing renal decline, suggesting its safe use in managing gout symptoms.
Researchers found that statin initiation was associated with a 33% reduction in all-cause mortality among AS and PsA patients. The study suggests that statins' dual benefits of lowering lipids and reducing inflammation may be the reason for this significant benefit.
A new Wnt inhibitor drug has shown significant improvements in knee OA pain, joint function, and even slowed or reversed cartilage loss. The study found that the drug improved outcomes for 76% of patients in the high-dose group compared to 36% on placebo.
A recent study published in JAMA Pediatrics found that receiving cardiopulmonary resuscitation (CPR) from a bystander improved overall and neurologically favorable survival for children with out-of-hospital cardiac arrest. The study analyzed data from over 3,900 cases and showed that conventional CPR provided better outcomes than compr...
A survey of over 1600 biotechnology professionals predicts that the Trump presidency will negatively impact NIH research funding and STEM education. Foreign-born researchers educated in American universities are also expected to leave the country due to a perceived
A recent study published in Frontiers in Cellular Neuroscience has made significant discoveries about the effects of anesthesia on brain activity. The researchers found that neurons under anesthesia become highly synchronized and more sensitive to environmental stimuli, which challenges traditional views on consciousness.
Researchers at The University of Texas at Arlington are studying the ideal physical and mental states to help individuals pay attention and practice self-control. They use computer-game testing combined with heart-rate and skin activity analysis to understand how people respond to tasks requiring attention and self-regulation.
A study found that 87% of school staff knew what to do in an emergency, but only 18% felt confident. The majority of non-nurse staff can identify the correct sequence of actions to take in case of anaphylaxis.
A study published in PLOS Biology found that Pavlovian approach can bias human information sampling, leading to irrational decisions. The researchers analyzed data from over 30,000 participants and identified three biases related to reward-driven behaviors, which were more pronounced with higher education levels and age.
Researchers from the University of Extremadura and Sapienza University of Rome have discovered a new type of convection in granular fluids. This lateral-wall thermal convection is produced by inert walls and exhibits distinct properties compared to traditional fluid dynamics.
Researchers at the University of Notre Dame have made a groundbreaking discovery that could pave the way for pancreatic cancer treatment. The study reveals that exosomes, tiny vesicles released by supporting cells, can educate cancer cells on how to survive chemotherapy, making the disease resistant to treatment.
A recent study published in Science Advances found that over 85% of pain-sensing neurons are sensitive to one specific type of painful stimulus. This challenges previous findings suggesting most neurons respond to all types of pain.
Researchers at Scripps Research Institute have identified a sub-region in the medial prefrontal cortex that synthesizes proteins for contextual fear memory. Inhibiting protein synthesis before memory formation prevents long-term recall, highlighting the critical role of early protein synthesis.
A new approach has been developed to measure the rate of movement of nitrate from groundwater into streams, which is critical for understanding how this pollutant moves through the environment and assessing water quality management. The research found that the rate of nitrate input to the aquifer dropped by 6 percent in 2013, while the...
Researchers developed a new laboratory system to study the deformed wing virus, showing viral antigens in all body areas, particularly in gland tissue. The discovery could lead to targeted strategies against disease-causing viruses and improve bee colony survival.
Researchers discovered that activation of the aryl hydrocarbon receptor pathway blocks collagen production and myofibroblast proliferation in thyroid eye disease. The study suggests AHR ligands may be a novel target for treatment, offering hope for targeted therapies.
New evidence from meteorites on Mars indicates a lasting drought on the planet, making it difficult for life to exist today. The study calculates a chemical weathering rate that shows rust formation takes thousands of times longer on Mars than in driest deserts on Earth.
Antibody drug conjugates (ADCs) have shown efficacy and acceptable toxicity, surpassing radionuclide conjugates in certain tumor types. Targeting cancer stem cells may further improve treatment outcomes.
Researchers developed a smartphone app that tracks eye movement to detect signs of autism spectrum disorder, with an accuracy rating of 93.96% and potential for earlier detection and better treatment outcomes.
Children who live at least half a mile away from a grocery store have higher rates of asthma, with 21% vs. 17% for those closer to a store. Limited access to fresh produce increases asthma risk.
A study by Cornell University researchers suggests that certain weeds, like milkweed, can be beneficial to crops and the environment. By incorporating these weeds into agricultural systems, farmers may reduce their reliance on pesticides and herbicides, while also supporting biodiversity and pollinator health.
A new study published in New Journal of Physics found that physicists pay less attention to articles with dense mathematical details, indicating real and widespread barriers to scientific communication. The researchers suggest improving clearer presentation of technical work is key to bridging this gap.
A new study by King's College London found that bullied children are nearly twice as likely to be overweight at age 18 compared to non-bullied peers. Chronic bullying in school was associated with a higher BMI and waist-hip ratio, independent of environmental risk factors.
A new study led by Indiana University researcher Susan Pressler will examine the impact of computerized cognitive training exercises on heart failure patients with memory loss. The study aims to determine if brain training programs, such as BrainHQ, can improve memory and quality of life for these patients.
A recent study found structural differences between the sexes in one part of the insula, a brain region involved in emotion processing. This difference may help explain why girls are more likely to develop PTSD than boys after experiencing trauma. The findings suggest sex-specific treatments for traumatic stress and emotion dysregulation.
A team of Italian scientists has created a hybrid device that links biological and electronic systems, leveraging pectin to replicate memristive behavior. The device features a double-layered polyelectrolyte structure that enables it to learn and perform logic/classification functions.
The American College of Allergy, Asthma, and Immunology recommends introducing peanut-containing foods as early as 4-6 months for high-risk infants with severe eczema and/or egg allergy. Early introduction has been shown to benefit infants who are sensitized to peanuts in studies like LEAP.