A study of 153,000 Australian children found that planned births before optimal time had poorer child development. Children born vaginally at full term had a lower risk of developmental issues compared to those born via planned birth or labor induction.
Researchers use gold nanoparticles with radioactive tracers to target cancer cells' telomeres, shutting down telomerase and halting growth. The method holds promise for delivering a lethal payload to cancer cells, improving treatment outcomes.
Researchers have developed a game-changing blood test that can identify concussions with greater than 90% certainty, using metabolomics to analyze small molecules in the blood. The test is unique and has been proven to be effective in distinguishing concussed patients from non-concussed adolescents.
Despite extensive research supporting mother's own milk as most effective option for low birthweight infants, numerous barriers persist in NICUs. Common issues include ineffective breast pumps, inadequate freezer space, and lack of investment in evidence-based practices to optimize milk volume.
A recent study analyzing seized African elephant tusks confirms that nearly all come from animals killed less than three years prior to seizure. The findings support evidence of widespread poaching and undermine the idea that many tusks are illegally recycled from older stockpiles.
Researchers from Duke University have identified two specific receptors, CXCR2 and LTBR, that play a key role in the development of drug-resistant multiple sclerosis. The study found that targeting these receptors may lead to successful treatment for patients who do not respond to interferon-beta treatment.
A nationwide study of Swedish children reveals a small association between exposure to surgery anesthesia before age 4 and slightly lower school grades at 16. Children with multiple surgeries had lower IQ scores, but the effects were small.
A new multistate research project aims to educate fruit and vegetable growers on agricultural water treatment systems. The project will develop a curriculum to equip growers with knowledge to successfully implement water treatment systems, reducing the risk of foodborne pathogens.
Pitt researchers discovered how oxidative stress accelerates telomere shortening by damaging DNA precursor molecules. This finding offers a new way to inhibit telomerase activity, potentially treating cancer. The study also reveals that oxidative stress can promote telomere lengthening.
A recent study published in Brain and Cognition found that lexical and semantic knowledge related to food is relatively well preserved even in diseases like Alzheimer's and Aphasia Primary Progressive. Food information was processed better than non-food, with caloric foods being more resiliently remembered.
A new study found that around 17% of women diagnosed with breast cancer visit their doctor with a symptom other than a lump. Non-lump symptoms, such as nipple abnormalities and breast pain, were more likely to delay diagnosis compared to those with a breast lump alone.
Research from University of North Carolina at Chapel Hill reveals that regions close to the equator are contributing more to the total global ozone increase due to their proximity to intense sunlight and heat. The study suggests that strategic policy planning is needed to address this issue.
Research suggests that obesity causes chronic inflammation in visceral adipose tissue, which leads to comorbid cardiovascular and metabolic diseases. A new study found that a specific T cell subtype associated with aging accumulates in obese mice, causing insulin resistance and obesity-like inflammation.
The journal Drug Delivery and Translational Research published a special issue on ocular drug delivery, highlighting the need for sustainable release of therapeutics to target tissues in the posterior segment. The market opportunity is significant, with the global pharmaceutical market projected to grow to $23 billion by 2018.
A telephone-based intervention has shown promising results in combating alcohol abuse among active-duty military members. Participants reduced their drinking rates and were more likely to seek treatment after a one-hour personalized intervention session.
Houston Methodist researchers identified a set of immune proteins that facilitate long-lasting immunity against malaria. The study found that elevated production of specific proteins regulating the immune system within 24 hours of infection was required for sustained anti-malaria immunity.
Researchers have developed a method for creating crumpled metal-oxide films using graphene templates, resulting in enhanced properties such as higher charge-carrying capacity and increased reactivity. This process allows for the introduction of wrinkle patterns on metal oxides, overcoming previous limitations.
Researchers have developed two new mouse models of amyotrophic lateral sclerosis (ALS) that exhibit protein clumping and display clinical features seen in patients. The models may help scientists better understand the disease and develop new treatments.
The transitional climate zone in East Asia experiences significant changes due to global warming, including coastward migration and aridity. Models largely reproduce the TCZ shape, but uncertainty from climate models dominates over emission scenarios.
A study published in Optometry and Vision Science found that protamine solutions perform at least as well as current disinfectant solutions in killing microbes that can cause contact lens-related infections. Protamine's broad spectrum of antimicrobial activity makes it a potential alternative for multipurpose disinfection solutions.
Sodium-oxygen batteries have shown improved cycle life and rechargeability thanks to a highly concentrated electrolyte solution. The new approach stabilizes DMSO in the presence of sodium, resulting in a passivating protective layer that enhances battery performance.
A team of researchers identified three novel proteins that act together on clock neurons to make the clock light responsive. The Quasimodo protein regulates light responses in the fly's clock neurons, controlling the circadian rhythm.
New UCL research reveals that blood vessels play a vital role in telling neural stem cells when and how to reproduce. The study found that preventing blood vessel growth interferes with normal neuron production, causing stem cells to disappear from the brainstem.
Researchers at MIT have demonstrated a comprehensive autonomous mobility system using driverless cars, golf carts, and scooters, all controlled by the same software. The system's modular design allows for easy deployment in new contexts and enables seamless information transfer between vehicles, enhancing overall performance.
Pancreatic cancer is expected to become the third leading cause of death from cancer in the EU by 2017. The number of deaths from pancreatic cancer will overtake breast cancer mortality rates in the EU, with 91,500 estimated deaths next year.
A recent study published in PNAS shows that people apply the rules of their spoken language to sign language, revealing a common structure between speech and sign. Researchers found that participants responded similarly to words and signs with doubling, regardless of linguistic context.
A study found that soiled clinical linens can contaminate surfaces with C. difficile bacteria, even in clean areas of a laundry facility. This highlights the potential risk of environmental contamination and emphasizes the importance of infection prevention in healthcare settings.
The Regenstrief Institute's Center for Biomedical Informatics has developed an open-source medical record system, OpenMRS, to support healthcare delivery in resource-poor environments. The platform has been widely adopted and adapted to address various global health challenges.
Researchers at IDIBELL have found a common cause of multiple resistance in cancer chemotherapy, highlighting the loss of TP53TG1 molecule as a key driver. This discovery has significant implications for understanding treatment failure and may lead to new therapeutic strategies to overcome chemoresistance.
A study of healthy postmenopausal women found that reproductive life events related to sex hormones positively impact cognition and verbal memory. Longer reproductive periods and earlier menarche are inversely linked with cognitive function.
A Canadian study of 421 children with new onset epilepsy found poor families had similar medical courses but less favorable social outcomes as adults. Poor children experienced more failure to graduate, unemployment, and psychiatric diagnoses.
Researchers have found that axolotl salamanders can regenerate significant portions of their adult ovary after injury. This ability could lead to new treatments for pre-mature ovarian failure and reduced fertility in humans.
Researchers have successfully tested a drug that shows early promise in preventing pre-term birth, which is the major cause of death in children under five years old. The drug, (+)-naloxone, was found to provide complete protection against pre-term birth and lead to normal development in infants.
Researchers found microscopic signs of microbial activity in ancient rock formations from South Africa's Barberton greenstone belt, dated at 3.22 billion years old. The discovery suggests life took hold on land as early as 3.2 billion years ago.
A comprehensive model estimates the cost of providing a set of essential medicines to all people in low- and middle-income countries. The model suggests that it would cost $13 to $25 per capita annually to ensure access to these medicines, with total costs ranging from $77 billion to $152 billion.
A study presented at TCT 2016 found the Watchman device had a successful procedure rate of 95.6% with low major complications, including pericardial effusion and embolization. New operators performed 50% of procedures, yet complication rates remained favorable.
Researchers analyzed diamonds from the Denver Museum of Nature & Science and University of British Columbia, gaining a rare look at the processes that led to Earth's crust formation. The study reveals an incredible 3-billion-year journey through tectonic collisions and volcanic eruptions.
Early and aggressive treatment with biologic drugs may halt progressive bone loss in patients with RA. Biologic therapies targeting specific cytokines and signaling pathways show protective effects on the skeleton.
The use of prescription opioids in Canada has increased steadily over the past 20 years, leading to a rise in overdose deaths and addiction. Experts propose several interventions, including guidelines for prescribing, limited dosages, electronic monitoring systems, and access to evidence-based treatment.
A new synthetic binding protein called NS1 monobody has been developed to block the activity of genetic mutations found in nearly 90% of pancreatic cancers. This breakthrough discovery provides insight into how RAS proteins function in cells, potentially leading to new therapeutic approaches for treating cancer.
Researchers found that bacteria that become dependent on their environment for essential nutrients outperform those that can produce them independently. The study's results suggest that this loss of autonomy may be an evolutionary advantage driving adaptation in bacterial populations.
Scientists at the University of Texas at Austin have discovered that separate populations of the same species can diverge in their gene regulation when adapting to their environment. This allows some corals to adapt better to changing conditions, while others struggle with diminished flexibility, leading to stress-induced bleaching.
Researchers at Stanford University have identified several biological markers that can measure the progression of Huntington's disease in non-neural tissues. The team found that levels of mitochondrial DNA were elevated in plasma samples from patients with the disease, and P110 treatment corrected these levels.
A new study found that regions with higher uptake of the program saw a 40% decline in hospitalizations to treat chronic conditions among indigenous Australians. Hospitalization rates dropped from 82.3 per 1,000 in 2009 to 61.2 per 1,000 in 2011.
Researchers found that costly ecological impact assessments failed to protect bats from fatal collisions with spinning blades. The study highlights the challenge of establishing with certainty the effect of major developments before they occur.
Researchers found that genetic background affects response to antibiotics on gut microbiome, insulin sensitivity, tissue inflammation, and metabolic functions in mice. This study suggests that genetic susceptibility plays a role in predicting the usefulness of microbiome therapies for obesity and metabolic disease.
A systematic review of seven studies found that low vitamin D levels are associated with an increased risk of bladder cancer. Vitamin D deficiency may be a key factor in preventing the cells within the bladder from stimulating an adequate immune response to abnormal cells, suggesting a potential mechanism for cancer prevention.
A human antibody that neutralizes Zika virus has been shown to reduce levels of the virus in placental and fetal tissues and decrease fetal disease in a mouse model of Zika infection. The findings suggest that this antibody could be developed to protect pregnant women and others from Zika-related complications.
The Light Plate Apparatus (LPA) brings optogenetics within reach of most biology labs with low-cost, easy-to-use hardware and software. Researchers can now incorporate optogenetics testing into their labs without extensive engineering or programming training.
Researchers at Oregon State University have developed an exceptional sensing device using diatoms and optical sensing, with sensitivity up to 10 million times higher than some common approaches. The technology has endless applications in health monitoring, environmental protection, and other fields.
A special journal issue explores solutions to chronic health problems, highlighting the importance of behavioral science in addressing health disparities. The issue features 24 scientific papers on leveraging behavioral science to promote healthy behavior change among vulnerable populations.
A new study by the University of Utah uses radiocarbon dating and genetic analysis to track the origin of seized ivory, revealing that nearly all shipments come from elephants killed in the past three years. This intelligence can help combat illegal animal product trade and inform strategies for protecting elephant populations.
Studies have shown that most mammals live longer in zoos compared to their wild counterparts, with smaller species exhibiting the greatest increase in longevity. This is likely due to reduced mortality rates from predation and intraspecific competition, which are prevalent in the wild.
A global GMO crop ban would raise food prices by 0.27-2.2% and add nearly a billion tons of CO2 to the atmosphere. This would lead to negative environmental consequences, including forest and pasture conversions that release stored carbon.
Researchers have developed a cheap and quick method to measure root biomass in soil-grown woody plants using electrical capacitance. This technique allows for rapid selection of individuals with optimal traits for breeding, enabling more efficient production of the important biofuel crop shrub willow.
A recent study published in Cancer Research found that emulsifiers in processed foods can alter the gut microbiota in mice, leading to increased tumor development and inflammation. The study suggests that dietary emulsifiers may be partially responsible for the increasing incidence of colorectal cancer worldwide.
A new technique allows researchers to quickly and cheaply generate DNA variants in a particular stretch of DNA, enabling the distinction between harmless and potentially hazardous genetic variations. This technique has the potential to speed up gene catalog creation and aid clinicians in interpreting genetic mutations.
Scientists have developed a new design for solar cells made from perovskite, achieving an average steady-state efficiency of 18.4%. The innovative tandem solar cell combines two types of perovskite into one photovoltaic cell, absorbing nearly the entire spectrum of visible light and outperforming traditional silicon-based solar cells.
A new study of over 14,000 childhood cancer survivors found that while treatments have extended their lifespan, patients do not report better health status. The study, which looked at three decades of therapy, highlights the need for interventions to improve quality of life and health outcomes for these survivors.
Researchers directly determined the relation between bandgap energy and size/shape of individual CsPbBr3 nanocrystals, revealing effective coupling between semiconductor NCs upon close contact. This study provides unique insights into interacting behavior of neighboring NCs and paves the way for designing large quantum structures.