A new $50 million center aims to accelerate the development of transformative therapies by shortening the path between research and clinical application. The center will provide preferred access to manufacturing facilities, shared innovation spaces, and workforce development opportunities.
Florida Atlantic University has received a $1.68 million grant from the Florida Division of Emergency Management to develop a framework for managing flood risks across the state. The project aims to help communities guide future mitigation projects and assist local communities in moving up in the Community Rating System.
Researchers exposed chicken embryos to pollutants in crumb rubber, leading to mass loss and developmental issues, as well as gene dysregulation. The findings suggest a need to reassess the potential toxicity of crumb rubber used in playgrounds and athletic fields.
Research in mice found that environmental enrichment can partially correct mis-mapped neurons in the visual pathway, leading to vision issues in adulthood. Mice raised in enriched environments showed less mapping errors than those in standard cages.
A study analyzed nearly 3,900 children's screen time use and its association with parental education levels and child sex. The findings highlight the importance of considering sociodemographic characteristics when examining screen time patterns.
MAIT cells play a key role in group A streptococcal toxic shock, producing large amounts of cytokines that cause over-reaction. The discovery has potential implications for diagnosis and treatment of life-threatening conditions.
Rates of cardiac events such as heart failure and myocardial infarction decreased up to 60% among First Nations people with diabetes in Ontario. However, hospitalizations and deaths remained more frequent compared to non-First Nations individuals.
Despite increased use of mechanized harvesting, aerosol and ozone particle concentrations remain unchanged since the prohibition of burning sugarcane in 2002. The researcher suggests that greenhouse gas emissions and particulate matter come from other sources.
Researchers analyzed tweets from 1,239 Republicans and Democrats to find no evidence that Russian trolls significantly influenced ideology or attitudes. The study suggests IRA accounts may not have polarized the US public due to interacting with highly polarized individuals.
Researchers at Martin-Luther-Universität Halle-Wittenberg have developed biodegradable rods containing an antibiotic to treat periodontal disease, reducing side effects and inflammation. The innovative treatment uses a combination of minocycline and magnesium stearate, releasing the antibiotic slowly and locally in the mouth.
Researchers found that normal gut bacteria boost norovirus severity in the lower small intestine but block it in the upper small intestine. The study suggests manipulating the gut environment through bile acids or microbiome could stimulate the immune system to shut down norovirus infection.
Researchers have developed coated seeds that can grow in salty soils by providing a protective coating and fertilizer-generating microbes. These seeds showed improved health and growth compared to untreated seeds in unproductive soil fields.
Researchers at the University of Toronto have discovered the brain cells responsible for nicotine aversion in mice, paving the way for new treatments to help smokers quit. The study found that dopamine neurons signal reward and GABA neurons signal aversion in the ventral tegmental area.
A research team identified that several types of highly aggressive pediatric brain tumors originate from stalled development of progenitor cells in the pons and forebrain. The findings represent a significant advance in understanding these diseases, which are the leading cause of cancer-related deaths in children.
A global health viewpoint emphasizes the need for accurate data to measure progress toward the United Nations Sustainable Development Goals. The lack of data in low- and middle-income countries, combined with inconsistent international standards, is hindering efforts to track progress.
Researchers discovered that lower dissolved oxygen levels trigger a shift in the marine nitrogen cycle, with ammonium replacing nitrate as the main fixed nitrogen component. This change indicates a significant biogeochemical vulnerability to ocean deoxygenation, potentially affecting nutrient availability.
A new UCL-led study found that living in a more polluted area is associated with a greater likelihood of having glaucoma, a debilitating eye condition that can cause blindness. People in areas with high levels of fine particulate matter pollution were 6% more likely to report having glaucoma than those in less-polluted areas.
New technologies have successfully established zeolite nanoparticle production methods, enabling size control and mass production. The 'bead-milling and recrystallizing method' produces nanoparticles < 100nm, while the 'particle growth method' generates larger particles from 150-300nm.
A Monash University study has made key discoveries into the role of gene expression in individual cell types of the brain, contributing to Alzheimer's disease. The research highlights the importance of understanding non-neuronal cells in treating this devastating condition.
A University of Houston research team is exploring the connection between macular degeneration and retinitis pigmentosa by studying the protein peripherin2. By modulating ROM1 levels, they found a way to convert severe macular degeneration phenotypes into less severe retinitis pigmentosa phenotypes.
Researchers have made breakthrough in recreating nature's efficient machinery for generating hydrogen gas using biological enzymes. The study focuses on iron-iron hydrogenase enzyme, which is faster and more efficient than current industrial process.
A team of researchers at Osaka University created a novel two-dimensional graphical tactile display that combines visual and tactile information. The display uses temperature-sensitive adhesive sheets to create a 'sticky' sensation, allowing users to feel objects on the screen.
The University of Konstanz's Collaborative Research Centre 969 will continue its research in cellular proteostasis with a new funding period starting January 2020. The centre will focus on studying complex processes and networks of proteostasis, developing new techniques to make these processes visible and controllable.
A new study published in Nature Microbiology has discovered that epigenetic chemical modifications play a crucial role in the survival and spread of C. difficile bacteria. The research found that inhibiting these modifications can reduce bacterial populations by up to 100 times, paving the way for potential treatments for this deadly i...
A pro-meat campaign on social media may have swayed undecided Twitter users towards the #yes2meat movement, surpassing balanced communications by six times. The study, published in The Lancet, analyzed 8.5 million tweets and found that critics of the planetary health diet reached 26 million people, despite having fewer followers.
Children's daily screen time increased significantly from age 12 months to 3 years, with an average of 150 minutes per day at 3 years. Higher levels of parental education and being born to first-time mothers were associated with higher screen time.
Researchers at the National University of Singapore have found that cells can attach to the fibrous protein meshwork surrounding them only if the fibres are spaced close enough. This finding has implications for understanding abnormal motility patterns in cancer cells and could lead to the development of new therapeutic targets.
A new study reveals that institutional failure, poverty, and social structures hinder women's ability to adapt to climate variability and change. Effective adaptation requires insights into what builds the adaptive capacity of women and men in specific contexts.
Tropical Cyclone Rita formed on Nov. 24 as a tropical storm and was analyzed by NASA's Aqua satellite using infrared light for temperature data. MODIS found powerful thunderstorms circling its center with cold cloud top temperatures indicating strong storms.
A study on valley oak found that populations grow faster at cooler temperatures, suggesting the need for new conservation methods to mitigate warming temperature effects. Selecting seed sources based on genotype may alleviate declining growth rates.
A new study found that fertility treatments cause epigenetic changes associated with rare diseases, while maternal age does not. Researchers used mice to dissociate the effects of technology and aging on gene expression.
Cycle benchmarking provides a solution to compare the capabilities of quantum processors across different architectures and applications. Researchers have made significant progress in characterizing errors in quantum systems, paving the way for establishing universal standards for measuring quantum computer performance.
Researchers found that a decline in ocean oxygen can break down feedback mechanisms controlling the marine nitrogen cycle, which is essential for all forms of life. The team used a data-constrained earth system model to show that extreme deoxygenation can lead to a collapse of the ocean's bioavailable nitrogen inventory.
Scientists are searching for the source of group E antibodies, which trigger most allergic reactions. They aim to deepen understanding of these molecules and develop effective treatments, as class E immunoglobulin is involved in one-third of all diseases.
Cornell University physicists have developed a self-assembling system using magnets to mimic specific binding in DNA. By controlling magnetic interactions, they can create unique structures and potentially build nanoscale machines.
A team of researchers from the University of Pennsylvania has discovered a crucial link between alcohol molecules and haze formation. Alcohols like methanol reduce particle formation by consuming sulfur trioxide, converting it to more sticky compounds that promote growth.
Men with more traditional views on gender roles tend to have higher allostatic loads due to stress, while those with progressive views are protected. Financial dependency on women is not linked to increased stress, but traditional beliefs about gender roles are.
Researchers found that recovering from metabolic syndrome significantly reduced the risk of cardiovascular disease in a nationwide population-based cohort study. In contrast, developing or remaining in metabolic syndrome was associated with an increased risk of cardiovascular disease.
Researchers from Russia and Germany discovered that activation of GDNF helps protect brain cells from death during hypoxic damage, maintaining neural network activity. This finding can lead to the development of an effective method for correcting CNS pathologies developing under oxygen deficiency.
Researchers found that xanthohumol and its derivatives can decrease microbiome diversity while reducing inflammation and improving energy metabolism in laboratory animals with high-fat diets. The study suggests that hops compounds may help combat metabolic syndrome by altering bile acid metabolism and changing gut microbiota.
The IKID project focused on Cambodia, Laos, and Vietnam's economic transitions, exploring challenges and opportunities in knowledge-based development. Key findings highlight the importance of supporting institutions for sustainable growth, innovative technology adoption, and individual wellbeing.
A team of scientists at the University of Freiburg has created a microfluidic chip that recognizes small RNA fragments, enabling faster and more precise disease diagnosis. The CRISPR biosensor can detect increased levels of miRNA in blood samples from patients with brain tumors.
Researchers discover that non-cancerous liver cells around tumors have the capacity to kill nearby tumor cells when hyperactivated, leading to reduced tumor burden and longer survival in mice. The study identifies YAP and TAZ genes as driving this anti-tumor mechanism.
The James Webb Space Telescope will study dwarf galaxy companions to the Milky Way and Andromeda, gaining insights into galaxy formation and dark matter. By measuring star motions, researchers hope to determine if some galaxies are grouped in a flat plane, which would have significant implications for understanding their formation.
Researchers at the University of Zurich have identified a new target for treating incurable leukemia in children by analyzing the molecular causes of the disease. They found that an abnormal protein activates genes at the wrong time, triggering the formation of malignant white blood cells and causing leukemia.
A new global map assesses the sustainability of food systems, considering factors beyond productivity and nutrition. The study identifies knowledge gaps and provides a standardized framework for measuring food system sustainability.
Researchers at Stanford University found that birds utilize drag to support their body weight during takeoff, employing lift as a brake in landings. This new understanding challenges conventional wisdom about the role of drag and lift in flight.
Researchers found brain damage in obese adolescents related to inflammation, particularly in regions controlling appetite and emotions. The study used MRI to track white matter damage and correlated it with inflammatory markers such as leptin and insulin.
The world's first 'Fisheries Index Insurance' scheme aims to protect Caribbean fishing communities from extreme weather events. However, policymakers must complement climate risk insurance with adaptations actions in coastal ecosystems to ensure its effectiveness.
Researchers studied the effects of a baseball's wake on its movement towards home plate. A stable seam position can create a pressure gradient that forces the ball downward or upward, left or right. The study highlights the potential for pitchers to manipulate the ball's trajectory and speed using this technique.
A bioarcheologist excavated a medieval Uzbek cemetery, discovering evidence of degenerative joint disease and healed fractures that suggest a heavy workload and level of care within the community. The dig site provides insight into how people adapted to harsh desert environments and interacted with other communities along trade routes.
A new study published in the European Heart Journal found that over one in ten cancer patients die from cardiovascular disease, including heart disease and stroke. The study analyzed data from over 3.2 million US patients diagnosed with cancer between 1973 and 2012, revealing that certain types of cancer, such as breast and prostate ca...
Researchers at OIST have characterized the structural defects that prompt ion movement in perovskite materials, which can destabilize the device. The study's findings may inform future engineering approaches to improve perovskite solar cells' performance and stability.
A new study by the University of South Australia found a significant disconnect between individual bushfire preparedness and community-level protection plans. To mitigate this risk, communities must band together to ensure everyone is informed and prepared for bushfires, including those living in peri-urban areas.
The NUS researchers developed a novel metal-based material using platinum and burnt paper, which is half as light as paper and can withstand temperatures up to 800°C. This material enables the creation of flexible and lightweight prosthetic limbs with real-time strain sensing capabilities.
Researchers at the University of South Australia are developing a new radioimmunotherapy agent to target and kill pancreatic cancer cells, potentially minimizing side effects. The treatment uses alpha particles to deposit energy inside cancer cells while leaving healthy tissue intact.
Researchers suggest a thermally induced fluid mixing approach could improve the delivery of anti-vascular endothelial growth factor agents to target tissue. This technique may reduce the amount of drug injected into the vitreous and increase effective treatment outcomes for patients with macular degeneration.
Scientists studied how environmental conditions affect archery accuracy and discovered that the best feather size depends on wind conditions. The research aims to provide a more accurate understanding of the physics behind optimal arrow design.
A study published in Cancer Immunology Research uses AI to analyze changes in CT scans before and after immunotherapy treatment, predicting patient response. The researchers found that textural changes, not just tumor size, are a better indicator of therapy effectiveness.
Researchers at Cornell University and Virginia Tech found that shaking the head to free trapped water in the ear canal can cause brain damage in small children, due to acceleration of up to 10 times gravity. A solution using liquids with lower surface tension, such as alcohol or vinegar, may help remove water without causing harm