Six leading scientific journals express concerns about EPA's 'Strengthening Transparency in Regulatory Science' rule, citing need for careful analysis of confidential data. The editors-in-chief emphasize the importance of informed decision-making based on full suite of relevant science vetted through peer review.
A study by Oregon State University found that 18 batches of supposedly pure human blood serum contained caffeine, cough medicine, and anti-anxiety drugs, highlighting potential issues with contaminated blood transfusions. The research also tested for interactions between botanical supplements and prescription drugs.
Research suggests that moderate coffee consumption is associated with a reduced risk of metabolic syndrome (MetS), a condition characterized by insulin resistance, hypertension, and obesity. The study highlights the potential role of polyphenols in coffee in reducing MetS risk.
The study found that the current system of immediate psychological help after a terrorist attack is inadequate, with most people seeking external help and expressing dissatisfaction with their GP's response. The researchers recommend improving the system to provide better support sooner.
The December issue of SLAS Discovery features articles on new screening tools and assays for medically relevant membrane protein targets. The special issue also includes reviews and original research papers on emerging protein-lipid reconstitution methodologies.
A study by researchers at the University of Montreal found that adolescents who spent more time on social media, television, and computers experienced increased anxiety symptoms. Decreasing screen time was linked to reduced anxiety. The study suggests limiting screen time may be a way to help teens manage anxiety.
Scientists have found two types of movement in nucleoli that contribute to healthy cellular function and may disrupt disease, including cancer. The research sheds light on the forces responsible for maintaining cellular integrity without membranes.
A new study suggests that extra-terrestrial impacts could have triggered the emergence of plate tectonics on early Earth. The research used modelling simulations and comparisons with lunar impact studies to reveal that massive impacts continued to shape the planet for hundreds of millions of years, potentially driving tectonic processes.
Researchers characterized the light-harvesting system of Chlamydomonas reinhardtii, a common unicellular green alga. The study reveals the assembly mechanisms and energy transfer pathways of the C2S2M2L2 supercomplex, shedding light on efficient light harvesting in green algae.
A study published in eLife analyzed ancient genetic data to investigate the decline of great auks. The findings suggest that intense hunting by humans likely caused their rapid extinction, even if the birds weren't already under threat from environmental changes. This highlights the potential for industrial-scale exploitation to drive ...
Researchers dissected protein pattern formation into its main functional modules and rebuilt the process from scratch, identifying the minimal ingredients needed for self-organisation. The new system produces less regular patterns than native systems but is still sufficient for reproducing basic biological processes.
Researchers from Queen Mary University of London and Zhengzhou University have developed a personalised vaccine system that can delay the onset of pancreatic cancer. The system was tested in mice, where it doubled their survival time compared to those without the vaccine.
Research published in the European Respiratory Journal found that women with severe asthma symptoms during pregnancy are at higher risk of pre-eclampsia, high blood pressure, and low birth weight. Babies born to these mothers are also more likely to have respiratory issues and congenital abnormalities.
Argonne researchers used a machine learning algorithm to relate known molecular structures to larger data sets, reducing computational costs while maintaining precision. The approach improved the accuracy of predictions about battery electrolyte candidates, enabling scientists to identify potential materials for next-generation batteries.
Researchers from the Hubrecht Institute and Utrecht University have set up a library of products derived from over ten thousand fungi to find new therapeutic compounds. They found 34 known compounds, including the cholesterol-lowering drug lovastatin, using zebrafish embryos as a test subject.
Scientists at University of Utah Health have discovered new genetic elements that could help control obesity and metabolic disorders. Hibernating mammals have evolved short non-coding DNA snippets near genes linked to obesity in humans.
The study determined the crystal structures of heme uptake system components HtaA and HtaB, revealing a novel fold for heme-binding/transport proteins. The results provide basic knowledge for developing new antibiotics against diphtheria.
New research suggests that fish size, not bypass system route, affects Snake River salmon returns. Larger fish survive at a higher rate in the ocean and as adults in rivers. The study found little evidence of delayed mortality once fish reach estuaries and oceans.
Researchers from Stanford University successfully recorded a blue whale's heart rate for the first time using an electronic sensor attached to the whale's flipper. The data suggests that the whale's heart is operating at its limit, which may explain why blue whales have never evolved to be bigger.
Device-associated infections show higher resistance rates for antibiotic-resistant bacteria compared to surgical site infections, highlighting the need for improved infection prevention and antibiotic stewardship in hospitals.
A study tracked honey bee nutrition and colony growth in Iowa's intensely farmed state. Colonies near soybean fields experienced short-term gains but failed to support long-term health due to lack of floral resources.
A Michigan State University study finds that antibiotic-resistant salmonella strains are increasing, leading to longer hospital stays and worse symptoms. The study also reveals regional differences in the types of salmonella infections, with rural areas affected by enteritis infections.
Research at University of Texas Health Science Center links concussions in high school students to depression and suicidal thoughts. The study reveals teenage males with concussion history are twice as likely to attempt suicide, while females have greater odds of reporting suicidal ideations.
A research project at the University of Córdoba and the University of Zaragoza analyzed legislative changes in water management in Spain, California, and the Murray Darling Basin in Australia. The study shows that despite similarities in agriculture and water scarcity, these regions have distinct approaches to managing their watersheds.
A new research training group funded by the German Research Foundation will investigate the role of interfaces in synthesizing soft advanced materials and manipulating their properties. The group aims to better understand self-organization processes in the presence of interfaces.
Researchers integrated human and animal treatment to eliminate roundworm infections and rabies in Tanzanian villages. The study found no difference in participation rates between combined and stand-alone events.
Researchers developed a mass-producible wearable sensor that can monitor levels of metabolites and nutrients in blood by analyzing sweat. The device is more sensitive than current devices, detecting lower concentrations of compounds like uric acid and tyrosine, which are associated with gout, diabetes, and cardiovascular diseases.
An international team of scientists analyzed 3 million species records from 200 ecological communities worldwide to reveal the impact of ocean warming on fish communities. The study found that subtle changes in species movement in response to rising temperatures made a significant impact on the global picture.
Researchers at Princeton University have developed models to identify internal states of the brain in fruit flies. By analyzing song patterns and behavioral changes, they discovered three distinct strategies - Close, Chasing, and Whatever - linked to specific neurons controlling these shifts.
A recent study found that honey bees fare well during the summer months when placed next to soybean fields, but struggle in winter due to a lack of food. Moving hives to prairie sites with late-flowering plants improved their nutritional health and helped them survive the winter.
An observational study found that hospitalists who worked irregular schedules, such as non-consecutive days, had better patient outcomes compared to those working consecutive days. The study suggests that varying work schedules may lead to improved patient care and outcomes.
A research team discovered that several types of highly aggressive and fatal pediatric brain tumors originate from stalled development of progenitor cells in the pons and forebrain. The cells' progress is arrested, and they transform into malignancies while retaining features of the original cells.
A new radiation therapy regimen combining lutetium-177 and actinium-225 has been shown to stabilize tumour growth and improve survival rates for patients with late-stage prostate cancer. The study demonstrated significant reductions in side effects, including dry mouth, compared to previous radionuclide therapies.
A study led by Newcastle University has identified circulating neuroblastoma tumour cells in the blood and bone marrow, providing new insights into the disease's progression. The discovery could enable non-invasive testing of targeted treatments and improve patient outcomes.
Researchers used computational fluid dynamics to analyze the swimming patterns of extinct ammonoid cephalopods, which lived over 300 million years ago. The study reveals insights into the stability of marine ecosystems and how they recover diversity after drastic extinctions.
Researchers at MUSC found that primary cilia generate approximately 60% of small EVs produced by renal tubule cells, with manipulation of cilium length affecting EV production. The protein content of EVs varies depending on cilia length, suggesting a significant role for cilia in intercellular communication.
Researchers tracked genomic changes in hybrid orangethroat and rainbow darters, finding regions with genetic divergence contributing to reproductive incompatibility. These differences likely disrupt cell division and alter gene expression, driving the evolution of distinct traits.
A role-playing experiment involving over 300 women from multiple countries suggests that female self-sexualization is linked to income inequality and social status anxiety. The study supports the hypothesis that social climbing and status competition drive sexualization among women.
Researchers have identified a key regulator in iron uptake in plants, which controls hundreds of genes and has the potential to increase iron potency in crops like rice and wheat. The study's findings could provide a solution to iron deficiency affecting over 2 billion people globally.
Skoltech PhD students won the Best Demo Award at ACM Siggraph Asia 2019 for their SwarmCloak technology, a novel system for landing flying robots onto the human arm. The team successfully demonstrated the tech over three days with no malfunctions.
A new study found an increasing rate of eye injuries related to nonpowder firearms among children, with BB guns accounting for most of the injuries. The study highlights the need for protective eyewear and stricter safety legislation to prevent preventable and serious injuries.
Extra-Tropical Storm Sebastien has transitioned from a tropical storm, coupling with a cold front and headed for the United Kingdom. The storm is forecast to affect southern England, with potential for heavy rain and flooding over the next several days.
Researchers used dance to convey the principles of fluid mechanics by creating a 'physics-constrained improvisation.' The goal is to produce an educational video that demonstrates flow past a cylinder at varying Reynolds numbers.
Scientists are testing a magnetically-actuated fluidic valve to reduce bleeding in trauma patients. The system uses an injectable magnetorheological suspension and externally placed magnets to create an obstruction, halting blood loss and stabilizing blood pressure. This could potentially extend survival time by at least 30 minutes.
Researchers found that people experiencing higher felt love had significantly higher levels of psychological well-being and extraversion personality scores. They also developed a method to analyze noisy data using Bayesian latent stochastic differential equations model.
Researchers at Pohang University of Science & Technology discovered a mechanism by which microbiota signals are transmitted to the entire body, controlling hematopoiesis in the bone marrow. This process involves CX3CR1+ mononuclear cells recognizing microbiota signals and releasing cytokines that stimulate the immune system.
A recent study found that most 2- and 3-year-old children fail to meet recommended daily screen time limits. Maternal screen time and home care were associated factors for non-compliance at younger ages, while only maternal screen time was significant at 3 years old.
Researchers discovered a fear-greed tradeoff in bacteria that use ancient respiratory quinones for aerobic respiration, leading to oxidative stress and growth limitations. The study provides fundamental insights into microbial bioenergetics evolution and potential strategies for modulating bacterial growth and survival.
Researchers discovered 25 springtails attached to a large winged termite and ant in 16-million-year-old amber from the Dominican Republic, showing a new type of hitchhiking behavior among soil-dwelling arthropods. This discovery highlights how symphypleonan springtails successfully achieved dispersal worldwide.
A secondary analysis of the NRG Oncology clinical trial shows that neurocognitive function (NCF) declines in half of patients with high-risk, low-grade gliomas up to a year after receiving temozolomide-based chemoradiotherapy. However, quality of life (QOL) remains stable or improves in these patients, according to the study.
Intergenerational occupational mobility in the US has declined since 1850, with relative decline in status of many occupations. Only a few high-status occupations retained stable percentile ranks, while recent generations face reduced upward mobility.
A team of researchers has developed an AI-powered system that can analyze placentas using computerized photographic image analysis, potentially improving health outcomes for mothers and babies. The system uses artificial intelligence to detect features linked to abnormalities and potential health risks.
Researchers estimate that 10% of the world's population suffers from a rare disease, yet accurate diagnosis remains challenging due to lack of standard definitions. A new commentary proposes a coordinated effort to define rare diseases, which could lead to better diagnosis and treatment for millions affected.
A survey of geriatricians, general internists, and cardiologists found that over 80% had recently considered deprescribing a cardiovascular medication due to adverse drug reactions. Barriers to deprescribing include concerns about patient reluctance and interfering with other physicians' treatment plans.
A study published in Nature Climate Change found that climate change is altering the mix of species in oceans, with warm-water species rapidly increasing and cold-water marine species decreasing. This shift can disrupt fisheries and ocean food chains.
Researchers found that brand is the biggest influence on bread buying behavior, followed by type of wheat and value considerations. Only 1% of surveyed consumers regularly purchase gluten-free bread due to perceived lack of value.
A Drexel University study found that rapamycin cream can reduce wrinkles, sagging, and improve skin tone in human subjects over 40. The drug blocks the TOR protein and has anti-aging effects by reducing senescent cells associated with skin aging.
A recent study published in the Journal of Pain found that inhaled cannabis reduces self-reported headache severity by 47.3% and migraine severity by 49.6%. The study analyzed archival data from over 1,300 patients who used medical cannabis to track changes in their symptoms before and after use.
Researchers at Rensselaer Polytechnic Institute develop a DNA star trap that captures and detects Dengue virus in the bloodstream, outperforming existing clinical tests by over 100 fold. The non-toxic, biodegradable test could be adapted to kill viruses as well.
The study identifies the proteins that make up the venom of the Hispaniolan solenodon, a rare and endangered species. The research reveals that these toxins are likely used to cause drops in blood pressure in vertebrate prey, and have evolved independently on at least four occasions in eulipotyphlan mammals.