The University of Copenhagen is excited to announce Zuber Lawler as a sponsor of the 12th Aging Research & Drug Discovery Meeting. The conference will bring together academia-pharma-startup-investor partnerships to discuss advancements in aging research and its applications.
A new study led by University of Waterloo researchers found that female pilots tend to make fewer flight control errors under stress, despite similar visual attention patterns. The findings challenge gender bias in aviation performance and suggest a need for more inclusive pilot training and evaluation systems.
A new research paper found that epigenetic aging is linked to cognitive decline in midlife, with twins experiencing a larger drop in IQ scores if they had grown up in families with lower socioeconomic status. This study provides new evidence for the impact of childhood adversity on brain aging.
Deep Origin will host two presentations at ARDD 2025, showcasing its AI-based models for drug discovery and longevity. The company aims to enable creation of virtual cells and deeper understanding of biological function.
A global study found that cancer immunotherapies carry a hidden risk: cholestasis, a serious liver condition. Researchers urge aggressive monitoring of liver function, particularly in younger adults and women.
Researchers at McMaster University have developed a promising new treatment for liver cancer by targeting metabolism in tumours. The discovery, published in Nature, shows that inhibiting an enzyme called ATP citrate lyase can enable the immune system to kill liver cancer cells, particularly through B cell-mediated responses.
A new study reveals that large language models can generate convincing but biased peer reviews, nearly indistinguishable from human writing. The AI excelled at generating persuasive rejection comments and fabricating reasons to cite unrelated studies, posing a serious risk to the integrity of scientific publishing.
A global analysis of CAR-T cell therapy found a significantly increased risk of developing secondary cancers, particularly T-cell lymphoma and myelodysplastic syndromes. The median onset of these cancers occurred much earlier in CAR-T recipients compared to those not receiving the treatment.
Researchers found that hot days increase emergency department visits and hospitalizations, while cold days are associated with fewer deaths, particularly among older adults. The study suggests that health policy needs to account for temperature-related impacts across different age groups.
Senescent T cells exhibit genomic instability, protein imbalance, and mitochondrial dysfunction, impairing immune function and recognizing tumor antigens. The presence of senescent T cells is associated with poor prognosis and reduced immunotherapy efficacy.
A new online tool calculates a person's 'heart age' based on cardiovascular disease risk factors, revealing significant gaps among certain groups. On average, women had a heart age of 55.4, while men had an average heart age of 56.7, with disparities found among those with lower incomes or education.
A team of geophysicists from ETH Zurich and SUSTech, China, used computer models to simulate whether a completely liquid core could generate a stable magnetic field. Their simulations showed that the Earth's magnetic field was generated in the early history of the Earth in a similar way to today.
A study published in PLOS found that urban exposure significantly increases the risk of obesity among middle and old-age migrants in India. The longer they stay in cities, the greater the risk of obesity.
A multi-institutional team has proposed updates to national guidelines to remove race-based assessments from lung function testing. The authors highlight the need for a more equitable evaluation system, warning against overreliance on objective cutoff-based criteria. Several healthcare systems have already shifted to race-neutral refer...
A team of international researchers has taken an unprecedented image of the heart of the OJ 287 galaxy, revealing a curved segment of the plasma jet. The discovery provides new insights into the extreme conditions surrounding supermassive black holes and their role in shaping the jets.
A new study found a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia. Individuals with long COVID face significantly higher rates of these disorders, alongside worse mental health and quality of life.
Bloomsbury is introducing Altmetric Explorer to track social attention and sharing of its publications, providing insights into reach, impact, and value. The tool will inform future editorial strategy and improve reader engagement.
A large-scale study found that zoos are often breeding endangered animals in skewed sex ratios, which can limit genetic diversity and increase the risk of extinction. The research highlights the need for zoos to collaborate and share data on their animal populations to manage conservation efforts effectively.
Researchers found that people who experienced malnutrition early in life may have survived threats like plague at greater rates until young adulthood. However, this survival advantage could drop significantly when entering middle and late adult years.
Long-term heat exposure negatively impacts students' cumulative learning, with complex tasks more affected than simpler ones. Lower socioeconomic groups face disproportionately greater impacts, underlining critical inequalities.
At ESC Congress 2025, over 40 pivotal studies will be presented, addressing major clinical questions and unmet needs in global cardiovascular care. The trials focus on innovative treatments for conditions like chronic Chagas cardiomyopathy and hypertrophic cardiomyopathy.
Recent scientific advances aim to enhance the efficacy of psychosocial treatments for mood and psychotic disorders, according to Dr. Marc J. Weintraub's upcoming webinar. Innovative approaches discussed include a mobile app adjunct therapy for adolescents at risk and psilocybin integration for adults with major depression.
Researchers discovered that cancer cells have a defensive mechanism to repair DNA damage and survive physical stress by activating mitochondria to pump in extra ATP. This finding could lead to new therapeutic approaches by targeting the mechanism's underlying scaffold.
A study found that users who exchanged daily walking steps for digital train tickets increased their walking by an average of 626.2 steps/day. Those using shopping coupon incentives walked 715.2 steps/day more on average than non-users. The results suggest effective promotion of active travel through well-designed mHealth apps.
The Brain & Behavior Research Foundation recognizes Joseph J. Taylor, Ash, and Harnett as recipients of the 2025 Klerman and Freedman Prizes for their outstanding work in mental illness research. Long Li receives the Freedman Prize for his basic research contributions to understanding depression and PTSD.
The new book highlights the transformative role of artificial intelligence (AI) and machine learning (ML) across various domains, including mechatronics, cybersecurity, digital health, and automation. Readers will gain practical insights into AI-based techniques in power systems, social media management, and healthcare diagnostics.
A recent study by UCLA researchers found that introducing new genetic variation from Texas reduced the influence of harmful mutations in Florida panthers, improving their fitness. However, the effect of this intervention may be temporary, and continued protection is needed to preserve the subspecies.
A team of astronomers captured a detailed image of a ribbon-like jet emerging from the heart of OJ 287, revealing extreme energy and motion near the black hole. The study sheds new light on supermassive black holes and their powerful jets, potentially offering clues to binary black hole mergers.
This book presents innovative nanomaterials for efficient pollutant removal from wastewater, reducing energy consumption and promoting eco-friendly treatment outcomes. It explores emerging trends and future directions in nanotechnology-based purification, providing practical insights for researchers and professionals.
A new study shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV. The treatment uses an adeno-associated virus to deliver instructions to muscle cells, which produce broadly neutralizing antibodies capable of neutralizing multiple strains of HIV.
Researchers from Trinity College Dublin develop a method to harness structural colour using microfabrication technique, enabling ultra-sensitive materials for environmental sensing and biomedical diagnostics. The breakthrough also paves the way for next-generation medical sensors that can track biochemical changes in real-time.
A UNLV study uses an mRNA cocktail to selectively route to the pancreas, reducing the risk of immune responses and side effects. The breakthrough offers new hope for treating pancreas-related diseases, including cancer and diabetes.
A team of researchers at Kyoto University has successfully developed a method to calculate the vibrations of black holes using exact WKB analysis. The approach reveals complex patterns in spiraling waves, enabling precise capture of frequency structure and bridging theoretical predictions with observational data.
A large-scale genetic study found ten new regions associated with the ability to detect specific odours, with three showing sex-specific effects. The research also uncovered a link between the risk of Alzheimer's disease and the sense of smell, highlighting the interconnectedness of these senses.
The EnIGMA framework demonstrates superior performance across multiple benchmarks, solving more than three times as many cybersecurity challenges as previous AI agents. The research also identifies a previously unknown phenomenon called 'soliloquizing,' where the AI model generates hallucinated observations.
A study in the Canadian Journal of Cardiology finds that delaying chest compressions to prevent tongue swallowing can lead to poor outcomes, including death or severe brain injury. The research exposes media-fueled misconceptions and emphasizes the importance of immediate CPR training.
Reinforcement learning world models are introduced as a promising tool for modeling complex atomic level changes in catalyst surfaces. The review presents advancements in using Dreamer-based architectures and multi-objective optimization strategies to address long-standing challenges in catalytic surface modeling.
Scientists generate collective molecular vibrations in a liquid by placing an electron ultrafast. These vibrations govern the electric behavior of the liquid and can be tuned to adapt its properties. The study reveals new insights into polar liquids' dynamics.
This article reviews bronchiectasis phenotypes and endotypes, exploring their impact on disease management and treatment strategies. Recent research has identified distinct inflammatory endotypes, guiding targeted therapies and improving patient outcomes through personalized approaches.
A recent study published in New Phytologist reveals a crucial gene necessary for plant reproductive structures. The gene, named SHOT GLASS, is found to regulate the development of air chambers and sexual organs in liverworts, a model organism for studying plant reproduction.
The Fibrosens project aims to develop a novel platform for real-time monitoring of fibrosis biomarkers in muscular dystrophies using nanoplasmonic sensors. The project will enable faster and cheaper testing of anti-fibrotic drug candidates, as well as personalized drug screenings for patients with specific mutations.
A recent study by Drexel University researchers analyzed 24 coastal New Jersey communities' communication of climate-related hazards. The analysis found wide variation in the number and extent of mitigation actions taken, with stormwater management and road improvements being the most frequently mentioned projects.
Researchers discovered that Candida albicans can persist in the mouse gut for at least 58 days without causing harm, and treatment with anti-fungal medication only reduced its presence. The fungus's ability to colonize was linked to the production of candidalysin and adhesins.
A multicenter study found influenza-associated acute necrotizing encephalopathy (ANE) carries a high risk of morbidity and mortality in children, with a 27% mortality rate. Survivors often experience neurological difficulties, emphasizing the need for rapid treatment and vaccination to prevent ANE.
Researchers developed an open-source software tool, Phoenix, to simulate light behavior in quantum systems, solving wave equations in record time without high-performance computing expertise. The program is up to a thousand times faster and 99.8% more energy-efficient than conventional tools.
This study uses AI to pinpoint optimal synergies in combination therapies, slashing experimental costs and accelerating discovery by up to 7.2% in accuracy.
Researchers found that high rates of coronary heart disease were linked to poverty, limited healthcare provider availability, and low broadband access. However, some counties with similar challenges reported lower-than-expected cardiovascular outcomes, suggesting the need for tailored strategies to address health disparities.
Cancer-associated fibroblasts (CAFs) exhibit paradoxical effects on immunotherapy, sometimes hindering and other times helping to control tumors. Research identifies specific CAF subtypes that enhance or suppress immune cells, offering promising targets for therapies.
A new study by Mass General Brigham found that states with flavored e-cigarette ban policies experienced a significant decline in e-cigarette use among young adults and adults, but a slower decrease in cigarette smoking rates. This mixed impact raises concerns about the unintended consequences of flavor bans.
Researchers from Japan studied DJ-1's catalytic mechanism, revealing key amino acids involved in cPGA hydrolysis. Mutations in these residues revoked cPGA hydrolase activity, confirming the pathophysiological implications of DJ-1.
A new AI-based technology analyzes mammograms to predict a woman's five-year breast cancer risk, outperforming standard methods by 2.2 times. The system provides an absolute risk score comparable to national incidence rates, enabling targeted prevention and early detection.
A $5.5 million federal grant will support clinical trials to treat fragile X-associated tremor/ataxia syndrome (FXTAS). The project aims to develop accurate outcome measures for future trials, ensuring patients and caregivers have a say in what matters most.
Researchers found that solar energy delivers the biggest climate payoff in certain US regions, with California and Florida seeing significant CO2 reductions. A 15% increase in solar power led to a reduction of up to 147.18 metric tons of CO2 in California alone.
Researchers have found electrolytes with boron additives can mitigate critical challenges of lithium metal batteries, including lithium dendrite formation and low Coulombic efficiency. The boron additives also improve the specific discharge capacity and high-rate performance of lithium-ion batteries.
Researchers from Italy developed a conductive biopaste to accelerate coral growth and a natural healing patch to target antibiotic delivery to diseased corals, both showing promising results in laboratory tests.
A study published in the Royal Society's Proceedings B found that closely related bat and bird species share the same habitat due to their shared evolutionary history. This challenges previous ideas about competition driving species apart, suggesting that animals with similar needs tend to group together in suitable habitats.
A new study reveals that a slowdown in the Atlantic Ocean current could halve annual precipitation in tropical regions, drying out rainforests and upending ecosystems. Climate change is predicted to weaken the current, leading to significant reductions in rainfall over Central America, the Amazon, and West Africa.
Researchers at the University of Basel have developed an engineered enzyme to precisely build complex molecules, such as pharmaceuticals and fine chemicals. The new approach uses metal hydride hydrogen atom transfer (MHAT) chemistry with enzymatic catalysis to produce three-dimensional molecules with single-handed configuration.
The CPADS web tool integrates data from GEO, TCGA, and GDSC databases to analyze gene expression changes, correlations between genes or drugs, and pathway enrichment in cancer samples. L1CAM was identified as a potential drug resistance target in non-small cell lung cancer through CPADS analysis.
The FDA has authorized artificial intelligence devices for Alzheimer's and related dementias despite limited demographic data. Disease status, age, sex, and race were reported for fewer than half of devices, raising concerns about real-world generalizability.