The Brain & Behavior Research Foundation awards the 2026 Pardes Humanitarian Prize in Mental Health to the American Foundation for Suicide Prevention for its sustained investment in rigorous scientific research and its humanitarian impact on suicide prevention. The Prize recognizes AFSP's contributions to advancing the understanding of...
A Columbia University School of Nursing study found that 63% of patients would not endorse AI-generated medical responses without a clinician's review. Patients prefer fast AI-generated responses for logistical tasks, but wait up to 48 hours for a doctor's review on medical questions.
A global survey of 102 cities across 31 countries has revealed over 40,000 new viral species, with 77% of them having never been described before. The study sheds light on the vast biological diversity of microorganisms in urban environments, revealing complex interactions between viruses and their hosts.
A new study from St. Jude Children's Research Hospital found that childhood cancer survivors living in socially or environmentally vulnerable neighborhoods are more likely to develop chronic health conditions. The study identified a doubled risk of overall chronic health condition burden compared to the least vulnerable neighborhoods.
Researchers unified magnetism, resolving water ice puzzle; a new framework classifies phases and phase transitions in classical pyrochlore spin-ice models. Sharp phase boundaries give way to smooth crossovers, with exceptions for spin 3/2 magnets.
A study from the Johns Hopkins Bloomberg School of Public Health found that US states with legalized online sports betting saw significant increases in antidepressant and anti-anxiety medication prescriptions, as well as outpatient diagnoses of depression and anxiety.
A recent study has identified unique genetic changes in brain tumors that recur after treatment, offering new insights into resistance to therapy. The research, conducted across 10 countries, found that different types of gliomas undergo distinct genetic changes, with some associated with poorer outcomes.
Researchers have discovered a vulnerability in water and energy networks that allows hackers to target and disrupt critical infrastructure without breaking encryption. By analyzing traffic patterns, attackers can identify critical communications and selectively block them, causing operational disruptions.
Roger Portell, director of invertebrate paleontology, retired after 42 years, leaving behind an extensive collection of over 7 million specimens. He also perfected strategies for organizing and managing museum collections, making it a key resource for paleontologists worldwide.
Researchers at the University of Cincinnati have developed a proof-of-concept gene therapy that targets and reduces the production of cerebrospinal fluid, potentially providing a minimally invasive treatment for hydrocephalus. The therapy uses an adeno-associated virus to deliver therapeutic genetic material into a patient's cells, wit...
Researchers have discovered a previously overlooked immune cell that can recognize and kill small cell lung cancer, a form of cancer with limited treatment options. The study found that patients with higher levels of these cells lived longer, uncovering a hidden immune defense that could be exploited to attack these hard-to-treat tumours.
Researchers have found that a single dose of the licensed Ebola vaccine can induce T cell cross-reactivity against the Bundibugyo virus, a closely related but distinct virus. This cross-reactivity may provide a level of protection against severe disease, although more studies are needed to confirm its effectiveness.
Researchers at UChicago PME developed a computational framework to model the full physics of spin defects, including internal conversion, a challenging process to predict. The framework sheds light on the utility of spin defects as qubits and could help design materials for quantum technologies and energy conversion.
A study of 1,020 men and women from Chennai found that a poor-quality diet may exacerbate the genetic risk of high blood cholesterol levels in Asian Indian adults. Genetic predisposition to diabetes, stroke, and heart attack may be worsened by a diet lacking essential nutrients.
An observational study of 533 Indonesian students found that LLMs enable personalized learning, which may enhance creativity by boosting analyzing and creating abilities. The study used Bloom's taxonomy framework and peer interaction to elevate higher-order thinking skills.
Researchers analyzed Italian paintings to discover the thorny oyster's cultural and culinary importance, shedding light on its 'forgotten history'. The study combined historical texts and testimonies to uncover the oyster's significance in art, archives, and cultural knowledge.
A UK study of over 13,000 children found that those with higher childhood body fat levels were more likely to experience body dissatisfaction in adolescence. The study suggests that both boys and girls with higher BMI or fat mass index trajectories in childhood are at risk of body dissatisfaction.
Rewilding tropical atolls with native vegetation and seabird populations could help islands keep pace with rising sea levels. The study found that these measures can boost coral reef growth and sediment production, reducing wave-driven erosion and increasing reef accretion potential.
A new DNA sequencing tool rapidly detected 11 harmful algal bloom species across 20 sites in Florida's Indian River Lagoon. The study found frequent co-occurrence of HAB species, suggesting shared environmental triggers or interactions that could help explain how blooms develop.
A study published in Science Advances reveals that bleached corals can fully recover within seven weeks through contact with healthy corals, opening new possibilities for restoration. The discovery could inspire the development of new methods to rapidly restore corals, which face severe threats from climate change.
A new study reveals that a diet high in white rice and low in fibre, fruit, and vegetables may increase cholesterol levels in individuals with specific genes. Researchers found a significant link between diet quality and genetic risk of high blood cholesterol in Asian Indian adults.
Researchers at Delft University of Technology have developed an AI system that enables a racing drone to navigate demanding courses at extreme speed using only a single camera. The system, called MonoRace, uses a compact neural-network-based control to achieve high-performance autonomous flight under real-world conditions, outperformin...
A team of researchers discovered an early base camp in Beringia, revealing life in the region 13,800 years ago. The camp featured a unique hafted-biface form, osseous tools, and well-preserved activity areas, showcasing human hunting of megafauna such as mammoth, bison, and caribou. These findings provide important insights into the ev...
A vaccine given to pregnant mice protected their newborn pups from a severe bloodstream infection caused by the dangerous bacterium Klebsiella pneumoniae. The study, published in Science Advances, points to a promising new strategy for protecting vulnerable infants from the drug-resistant superbug by harnessing maternal immunity.
Scientists at the Salk Institute have discovered a plant cell receptor called SRF3 that restores iron balance and prevents immune overreaction to microbial invasion. This study provides crucial insights into plant resilience and could shape future agricultural efforts to feed a growing global population.
Researchers have discovered that brief physical contact between healthy and bleached corals can restore symbiotic algae, allowing for faster recovery times. This process occurs via tissue fusion and is successful only for corals from the same genetic background.
A comprehensive study of 18,476 Chinese participants reveals 'clocks' of human aging that can predict chronic disease and mortality. The research provides clinically relevant metrics for health monitoring and disease prevention, shedding light on aging's impact on metabolism.
Researchers developed an mRNA antibody therapy that can neutralize SARS-CoV-2 and evade its escape mechanisms. The therapy, which combines structural engineering and mRNA technology, shows promise in protecting against emerging variants, including the XBB.1.5 and JN.1 variants.
The fight against antimicrobial resistance is threatened by drug-resistant tuberculosis, highlighting the need for preventative frameworks and holistic control measures. New AI technologies and strategies are being developed to tackle the threat, including the use of genomic surveillance and streamlined clinical trial designs.
A new small molecule therapy targets the brain's microglia cells to protect neurons, reducing markers of neuronal damage and inflammatory signaling. The therapy, VG-3927, is well-tolerated and penetrates the central nervous system, reducing levels of a marker of TREM2 in patients with Alzheimer's disease.
A new study analyzing over 2,300 burials in ancient China finds that social-relational networks shaped inequality long before the rise of states. These networks controlled access to labor, resources, and symbolic capital, producing unequal social-relational networks that predated state formation.
Co-exposure to heatwaves and landscape fire smoke has increased globally, affecting 55.9% of the global population between 2000 and 2019. The top 5 countries with highest annual averages of co-exposure were the Democratic Republic of the Congo, Indonesia, Mexico, Brazil, and the Russian Federation.
The discovery at Shég' Xdaltth'i' provides evidence for a trans-Beringian cultural link between Alaska and other western sites, dating back 13,800 years. The site's tools and artifacts, including hafted-biface forms and pre-Clovis material, suggest a connection between Beringian and Paleoindian cultures.
Researchers found that breast milk antibodies can neutralize multiple respiratory viruses, including influenza, RSV, and adenovirus, in mouse models. The study suggests that these antibodies could be used to prevent seasonal influenza and pandemic responses.
A new study found that insomnia disrupts the body's ability to learn and remember that a threat is gone, leading to a reduced capacity to extinguish physiological threat responses. This is associated with a reduced safety memory and increased arousal during recall.
A recent study revealed that corn cultivation played a crucial role in the subsistence and development of large villages in the Brazilian savanna. The research, which analyzed minute chemical variations in human bones and teeth, provided a record of diet throughout life. Corn consumption was comparable to that of Mayan and Andean popul...
A new international study found that population levels in Japan after the Kikai-Akahoya eruption were more complex than previously believed. The research team discovered that while populations declined in some areas, they actually increased in others, with survivors adapting to new social relations and economies.
A new algorithm enables off-the-shelf computers to run quantum simulations previously only possible using the world's most powerful supercomputers. This breakthrough could make it cheaper and easier to run experiments vital for understanding the limitations of current quantum computers.
A 20-year study reveals that 287 million people globally were exposed to both heatwaves and wildfires on the same days, with over half of the world's population affected. The study warns that cardiovascular and respiratory illnesses will continue to increase as climate warming leads to more combined heatwaves and wildfires.
Researchers have developed TMD-based systems with strong and broadband absorption, achieving efficient impedance matching and energy attenuation. Multicomponent systems can push performance further, offering multifunctional architectures with thermal and mechanical functions.
Recent advances in wearable electronics are transforming these devices into promising platforms for continuous, personalized precision diagnosis. The integration of multiple sensing modalities and artificial intelligence enables early disease detection, longitudinal health monitoring, and personalized medical management.
A study by Semmelweis University researchers found that adolescents with functional abdominal pain disorders experience multisite pain and report stress, anxiety, and social struggles. These symptoms can persist for years and impact daily life, highlighting the need for further investigation and support.
A new analysis of US national health data found that inflammation increases across the stages of cardiovascular-kidney-metabolic syndrome, with the largest increase at the earliest stage. Average hs-CRP nearly doubled between stage 0 and stage 1, crossing the 2 mg/L threshold commonly used to signal increased cardiovascular risk.
A review argues that a lack of analytically validated measurement systems is the primary obstacle to the clinical translation of RNA 5-methylcytosine (m5C) in cancer. Altered m5C pathways have been linked to tumor progression and therapeutic resistance, but only a small fraction of candidates have advanced toward clinically validated b...
Researchers have identified AsLOX2 as a key gateway enzyme that oxygenates α-linolenic acid to form a saclipin-related intermediate. The team then tested whether the intermediate could be converted into saclipins through a series of chemical reactions, demonstrating a practical route toward saclipin production.
A new study develops a model to compare benefit-package options under a constrained healthcare insurance budget, considering clinical efficacy and household out-of-pocket expenditure. The model, TPCPSO_BD, performs better than comparison algorithms in small, medium, and large test cases, reducing direct household expenditure by 48.97%.
A nationwide study found diamide insecticides in 47 Chinese cities, with concentrations ranging from undetectable to 119 ng/L, and a national median of 40 ng/L. The study highlights regional pollution patterns and unexpected exposure risks to human populations, particularly children.
A new study from Toho University found that wearable robot training improved walking distance in patients with ALS by nearly 12 meters in a two-minute test, while quality of life remained stable. The study suggests that walking performance may improve without a measurable decline in quality of life, but larger controlled studies are ne...
A new laboratory study uses large-amplitude oscillatory shear and Fourier-transform rheology to track the shift from solid-like to fluid-like behavior in loess mudflows as deformation increases. The study identifies four strain markers that distinguish the linear regime, nonlinear yielding, and the solid-liquid crossover, with water co...
Researchers at TU Wien and MedAustron have developed a new approach combining carbon and helium ions to monitor tumor anatomy during treatment while destroying cancer cells. This method allows for reduced safety margins and spared healthy tissue, particularly near sensitive organs.
Research found that micro-nano bubbles increase redox potential, enhance carbon, nitrogen, and phosphorus cycling genes, and reduce greenhouse gas emissions in waterlogged soils. This technology provides a low-cost green remediation pathway for waterlogged farmland.
The Tree of Life programme aims to sequence the genome of every findable species in the UK and Ireland. The programme has introduced a new semi-automated process to publish and review genome notes, expanding access to research that supports advances in agriculture, conservation, and medicine.
A study by Anglia Ruskin University found that honeybees dominate wild pollinators when competing for food, restricting access to resources and physically displacing other species. The researchers recorded aggressive interactions initiated by honeybees, which often resulted in the loss of forage for other pollinators.
A study reveals drought stress is the primary factor amplifying Xylella fastidiosa's impact on almond trees, challenging the notion of natural environments as buffers against disease. Climate, water stress, and shrubland vegetation play a crucial role in disease spread and tree health.
A University of Bath study identified a paradox where consumers view businesses as more sustainable when they add eco-friendly items rather than removing them. The researchers found that people consistently reward visible eco-friendly additions but give little credit to businesses that reduce or remove products.
A nationwide Finnish registry study investigated medication-related osteonecrosis of the jaw in breast cancer patients receiving antiresorptive treatment. The study found that 12.6% of patients developed the condition, with associations between dental procedures and its risk. The findings emphasize the need for close collaboration betw...
Researchers identified fagopyrine, a naturally occurring compound in buckwheat, as a potential starting point for developing new AKT1-targeting drugs. The analysis revealed substantial variation in AKT1 expression across 33 cancer types, with increased expression linked to poorer outcomes in certain malignancies.
This comprehensive review synthesizes molecular mechanisms, current therapeutics, and emerging strategies in esophageal cancer. The findings highlight breakthroughs in immunotherapy and promising future directions in targeted therapies.
Research by the University of Warwick found that children born smaller than expected at birth tend to achieve lower scores in maths and reading, with the link persisting into mid-teens. The study of over 92,000 children suggests that monitoring a baby's growth and ensuring proper support is crucial for their development.
A joint team proposes a top-down strategy for controllable synthesis of chiral nanostructures in optical crystals using femtosecond laser pulses. This method enables the creation of chiral materials with unique optical responses, distinguishing between spin states of light, and has potential applications in encrypted optical communicat...