Sylvester researchers develop AI-powered fracture prediction models, train as wildland firefighters to reduce cancer risk, and discover new targets for pancreatic cancer treatment. A new tumor-on-a-chip model shows how pancreatic cancer hijacks immune cells.
A Mayo Clinic-led study found that continuing maintenance therapy beyond two years did not improve overall survival for patients with standard-risk multiple myeloma. The findings suggest that treatment duration can be safely tailored, reducing treatment burden and costs.
A team of researchers from Saitama University has discovered a natural peptide aptamer called Calmodulin-binding peptide (CBP) that can selectively recognize two structurally distinct proteins, calmodulin and human midkine. CBP binds to calmodulin in the presence of calcium ions and to human midkine in the presence of sodium ions.
A research team used a simple physical model to connect sublattice melting with cooperative and spatially heterogeneous ion transport, revealing a fundamental mechanism behind superionic conduction. The findings offer a unified explanation for this phenomenon, which could guide the design of next-generation solid-state batteries.
A new study from UT Health San Antonio found a link between long sleep hours and higher levels of an Alzheimer's-related protein in the blood. The research suggests that long sleep may reflect early neurodegenerative processes, but more sleep is not always better for brain health.
Researchers argue that social media restrictions should be viewed as part of a complex system rather than isolated policies. They suggest using systems mapping to anticipate effects and design more balanced approaches, considering factors such as school engagement, social connections, and industry responses.
A systematic review and meta-analysis found that weight loss drugs can reduce key symptoms of binge eating disorder, including binge eating episodes, loss-of-control eating, and emotional eating. The study suggests that these medications could be an important part of treatment plans for people with binge eating disorder.
A study found that Black African and Caribbean women in the UK are less likely to attend breast cancer screening due to limited knowledge and trust issues with healthcare providers. Researchers recommend stronger links between GP practices, breast screening services, and community champions to improve awareness and attendance.
KAIST develops robot that can autonomously choose gait strategy for its surroundings, switching between walking, running, jumping, and other locomotion skills. The team generated 15.5 hours of training data using computer simulations alone, enabling the robot to move quickly and stably in real outdoor environments.
Researchers analyzed data from over 500,000 births in Scotland to examine the effects of epidural analgesia on newborn health. The study found no association between epidural use and serious neurological conditions, sepsis, or cerebral palsy in childhood.
Data shows Black doctors are up to 30 times less likely to be offered medical training posts, with some specialties seeing a gap of over 100-to-1, while Asian applicants face similar challenges. The findings highlight ongoing barriers faced by ethnic minorities in the UK health service.
Researchers developed an analytical technique to evaluate culture media quality by analyzing patterns of fluorescence from synthetic polymer probes. This technology detects quality differences in serum, stem cell, and microbial cultures with high precision, improving reproducibility.
Researchers are engineering biochar-based composites to overcome limitations, such as insufficient adsorption capacity and limited selectivity for certain emerging pollutants. The new review highlights the importance of balancing treatment performance with environmental safety throughout the material's life cycle.
A condition affecting 170 million adolescents and women worldwide is being redefined to capture its complexity, including its far-reaching health impacts on metabolism, mental health, and reproductive systems. The proposed name change aims to improve awareness among patients and providers, encouraging more comprehensive care.
A new study uses machine learning to predict chemical toxicity in rare and endangered species, reducing the need for direct biological testing. The model achieved strong performance predicting acute and chronic toxicity, with life stage being a key factor.
A new study reveals that carefully designed power cycles can convert more of LNG's overlooked resource into useful electricity. Researchers found that a two-stage Rankine cycle with reheating produces the most effective design, generating up to 9.2 megawatts of net power.
The ECOG-ACRIN ENDURANCE trial found that indefinite lenalidomide maintenance had no survival benefit and more toxicity compared to stopping treatment after 2 years in patients not undergoing a stem cell transplant. The study suggests that fixed duration treatment can significantly reduce healthcare costs.
Researchers at Texas A&M University have found a way to intervene early in traumatic brain injuries using a natural, gut-derived chemical that prevents post-traumatic epilepsy from taking root. The treatment reduced brain inflammation, improved memory and mood, protected brain cells, made seizures both rarer and harder to trigger.
Scientists harness non-Abelian anyons to perform any operation a quantum computer needs, eliminating the need for expensive magic state distillation. The approach enables fault-tolerant computations and has potential applications in quantum error correction and basic physics research.
A new study from the University of Washington highlights the potential consequences of losing roadless protections on rivers and drinking water supply. The study found that over 80,000 miles of rivers receive some protection from the rule, reaching 25 million people across the country.
Scientists at MD Anderson Cancer Center have identified a previously unknown mechanism by which T cells attack and eliminate acute myeloid leukemia (AML) cells. The discovery reveals that AML cells use a CD64-dependent pathway to evade traditional MHC recognition, potentially explaining why AML is sensitive to immune-based treatments.
A recent study published in Neurology found that Black individuals born outside the US have a significantly lower risk of stroke compared to those born in the US. The study, which analyzed data from over 64,000 adults, also found that immigrants who arrived within 15 years of the survey had a 73% lower odds of stroke.
A study reveals that forests and rivers work together to strengthen amphibian microbiomes and protect them from a deadly fungus. The research found that disconnected habitats impair the ability to recruit defensive microbes.
A pair of studies by NYU psychology researchers found that teaching leadership is not an innate trait and encouraging diverse mental representations of successful leaders can significantly increase teens' sense of belonging in leadership roles. By changing young people's views on leadership, the research suggests strengthening ambition...
A study found that college students who spent more time online and experienced online harassment were more likely to report suicidal thoughts. Cisgender men showed the strongest link between time spent online and suicidal thoughts, while online harassment was linked to higher risk across all gender groups.
The Perseverance rover has discovered evidence of repeated asteroid impacts creating a 3.9-billion-year-old 'weather report' from early Mars, preserving a record of variable-sized impacts and potential interaction with water or ice. The findings offer insights into one of the most turbulent chapters in the solar system's history.
A new study finds that most Americans view illicit drugs as a serious national problem, but perceive little progress in addressing it. Perceived progress on drug policy is strongly linked to political affiliation, with Republicans and Democrats having starkly different views.
A rare case report highlights the challenges of diagnosing cervical angioleiomyoma, a benign tumor presenting symptoms similar to those of common gynecological conditions. The study describes a successful surgical excision and excellent clinical outcome for a young woman with persistent heavy menstrual bleeding and pelvic pain.
New research reveals altitude-dependent carbon storage mechanisms in diverse forest ecosystems. High-altitude conifer forests excel at storing carbon in biomass, while lower-elevation mixed broadleaf forests stabilize soil carbon. Effective forest management requires altitude-specific approaches to conserve biomass and enhance soil org...
Canadian agri-food leaders recommend strengthening food infrastructure, improving preparedness, and building resilience to protect against geopolitical threats, biological threats, trade disruptions, and supply chain vulnerabilities. The report outlines seven key recommendations to ensure Canada's long-term food resilience.
Researchers at St. Jude Children's Research Hospital discovered that smaller sub-compartments within the nucleolus form to finish the final steps of ribosome assembly. These sub-compartments lock major ribosome building blocks together until they are assembled, preventing a key protein from associating with them prematurely.
A new award will help advance the proof-of-concept work toward commercialization of an at-home HIV test that detects cases not caught by lab tests. The device, called Click Chemistry Amplified Nanopore (CAN) sensing, has shown promising results in early studies.
The University of Minnesota Medical School research team has received a $10 million NIH grant to study how animals fight infection. The team will utilize a 'cellular zoo' of living cells from over 100 animal species to understand how different species recognize and respond to viral infections.
Scientists have found a way for the circadian clock to produce a winter version, which can suppress reproduction and alter activity patterns in fruit flies. This discovery could lead to new ways to disrupt pest populations and improve human health by better understanding seasonal influences.
The 24hreview initiative presents a standardized, shared pre-submission integrity layer for the global academic publishing community. The platform has already piloted its approach with Wiley and seen reliable verification of manuscript integrity within 24 hours.
Scientists have unveiled a new structure of the kinesin-1 protein, showing how cells control its on-off switch. The discovery could shed light on incurable neurodegenerative diseases such as ALS and Charcot-Marie-Tooth Disease Type 2.
Researchers developed a hybrid technology combining human learning and machine learning in noninvasive BCIs, producing rapid and sustained gains in motor imagery control. The study demonstrates significant scientific and technological advancement in BCIs, establishing a scalable pathway toward robust neural interfaces.
A new species of colobus monkey, 'Likweli', has been identified by its distinctive facial markings and unique call. The rare species is found in the dense forests of Lomami National Park and is considered Endangered due to its small geographic range and population size.
A previously unknown species of African monkey, Colobus congoensis, has been identified in the Democratic Republic of Congo. The species, known locally as Likweli, features a distinctive orange face patch and is one of the rarest discoveries in modern primatology.
Scientists have discovered that marsupial forelimbs rapidly develop over a four-day period, challenging current understanding of limb development in vertebrates. This finding highlights the unique biology of marsupials and has important implications for conservation efforts.
Researchers developed a new way to uncover differences in how viruses infect and destroy individual microbial cells. The study used a mathematical modeling framework to analyze infection outcomes in individual cells, revealing striking accuracy and new insights into viral behavior.
Researchers have developed a new drug candidate, SB-0110, that boosts L-dopa's benefits while reducing dyskinetic side effects in animal models of Parkinson’s disease. The compound preserves the gene-activity patterns tied to L-dopa’s benefits while counteracting biological changes associated with dyskinesia.
A study published in PLOS Climate found that teleworking can reduce carbon emissions from commuting, but this benefit may be offset by increased utility use at home. More frequent and separate home office users produced higher emissions due to work-related housing and technology use.
Researchers found that providing honeybees with prebiotics and probiotics helped them survive thermal stress. The study suggests these nutritional supplements can buffer the survival of bees and improve antioxidant enzyme activity.
A groundbreaking study published in Science Translational Medicine has successfully restored the sense of touch in individuals with spinal cord injuries using brain-computer interface technology. The study found that electrical pulses delivered to the somatosensory cortex remained stable and localized over a period of up to 10 years, w...
Researchers from the University of Tokyo used limpet shell analysis to reconstruct the journeys of tiny creatures between hydrothermal vents, finding they explore sunlit upper ocean during larval stage. This discovery helps explain how animals living at isolated vent sites can spread over hundreds or thousands of kilometers.
A New Jersey meteorite contains high concentrations of salt and briny fluids that can create molecules vital for life on Earth. The discovery sheds light on the chemical origins of life on our planet.
The Trump administration's 2025 repeal of the US Roadless Rule could put 25 million Americans at risk due to loss of access to pristine watersheds. The study assesses the value of this rule for both human health and nature.
Researchers reconstructed past methane concentrations using clumped isotopes in air from the past, revealing significant changes since industrialization began. The study suggests human activities are disrupting the balance between methane emissions and breakdown, driving rising atmospheric methane concentrations.
Researchers have developed ultrathin, invisible on-skin electrodes that can measure biological signals without altering appearance or social interactions. These new sensors achieve this by closely matching the appearance and texture of natural skin, reducing reflections and eliminating visibility.
A study analyzing county-level data reveals broad geographic patterns and local factors influencing breastfeeding initiation in the US. Localized approaches addressing disparities in breastfeeding initiation are necessary to complement national policy efforts.
A German analysis explores how COVID-19 disrupted typical transmission patterns of respiratory diseases, leading to shifts in their seasonal surges. The study found that population-level loss of immunity after the pandemic caused a buildup of susceptible hosts, resulting in earlier peak weeks for these surges.
Researchers confirm discovery of new African monkey species Colobus congoensis, previously unknown in over 75 years. The species is distinct from other African colobus monkeys with unique cranial, dental, and skeletal characteristics.
A study in PLOS One identified T. rex as the likely cause of some tooth marks on fossils from Cretaceous-era Wyoming, providing insights into animal behavior and ecosystem dynamics. The researchers developed a guide to interpret tooth traces on fossils, distinguishing between natural and bite-related marks.
A study analyzing 30,527 English dementia patients found hospital readmissions associated with multiple factors including sex, health conditions and post-discharge care. The research highlights the importance of monitoring and managing these risk factors to prevent hospital readmissions.
Researchers found that horses' heart rates increased when viewing wolves, regardless of behavior, while keeping a poker face and not displaying overt behaviors. The study's findings have implications for horse welfare and rider safety, as horses may be experiencing internal agitation without physical signs.
A new analysis of over 110,000 papers submitted to Science and Science Advances reveals Western scientists, larger teams, and top-ranked universities have slight advantages in acceptance rates. The study provides insights into editorial dynamics and outcome disparities, shedding light on the peer review process.
A new study from Griffith University reveals how different cave environments leave distinct 'fingerprints' on skeletal remains, providing a powerful tool for reconstructing past environments and histories in challenging conditions. Bones preserved in underwater caves often preserve their structure and surfaces remarkably well, while un...
A University of Colorado Boulder-led study analyzed over 110,000 manuscript submissions to top-tier scientific journals, revealing that prestige, topic, and location matter most in determining publication. The study found a significant disadvantage for authors based in China and those studying social sciences.
Researchers analyzed isotope data from over 100 individuals to find that some societies relied heavily on maize grown within diversified agricultural systems. These communities developed resilient polycultural food-production systems combining domesticated crops with wild plants and local ecological knowledge.