The Salk Institute has promoted Julie Law to full professor and appointed Talmo Pereira as assistant professor, highlighting their innovative approaches to gene regulation and computational neuroscience. Their research focuses on epigenetics and artificial intelligence techniques, respectively.
A new simulation- and AI-based approach reduces the time and data needed for brain MRI scans, achieving a high level of accuracy with only 10% of the data required. This breakthrough could translate to a significant reduction in scan time, enabling more patients to be treated in the same amount of time.
The Max Planck Institute for Polymer Research has launched a new international visiting student program with Virginia Tech, providing six graduate and undergraduate students from the US with three-month research opportunities in Mainz. The Poly-ABROAD Program aims to strengthen international scientific exchange in polymer and materials...
A new study links amino acid-driven oxidative stress to therapeutic vulnerability in Acute Myeloid Leukemia (AML) by targeting the UCP2-BCAA-PI3K/AKT/mTOR signaling axis. Suppressing UCP2 impairs leukemic cell proliferation and triggers apoptosis, while BCAA-induced oxidative stress activates this pathway.
A new AI model developed by researchers at the University of Witwatersrand has successfully simulated human-like language development in children. The model, which uses deep linear neural networks, demonstrates how language structures and becomes more complex over time, mirroring how humans learn and transmit knowledge.
Research highlights the dual role of eosinophils in cancer, with higher counts associated with reduced risk and improved treatment response to immunotherapy. The immune-activating effects of eosinophils may help predict treatment outcomes and anticipate complications.
Researchers summarize how AI is accelerating inorganic biomaterial development for various biomedical applications. AI-powered property prediction and inverse design tools are being used to discover effective materials with unique properties.
A national analysis found that robotic-assisted cholecystectomy remained linked to increased bile duct injury risks despite growing use. The study suggests small differences in overall complication rates between approaches.
Scientists have developed a new method to manipulate heat transfer using carefully engineered metamaterials, boosting it by up to four times. This breakthrough could lead to more efficient cooling strategies for electronic devices, improved thermophotovoltaic systems, and enhanced sensing technologies.
Researchers at Duke University School of Medicine identified a new mechanism by which G protein-coupled receptors (GPCRs) control signaling in cells. They found that β-arrestin proteins can assemble into liquid-like clusters known as condensates, acting as hubs to organize signaling molecules.
Dr. Sharon Giordano and Dr. Eduardo Vilar-Sanchez receive ASCO Special Awards for their transformative work in breast cancer research and prevention, respectively. Their contributions advance understanding of cancer and improve patient outcomes.
A recent study published in JAMA examines the effectiveness of hearing aids for adults with mild to moderate hearing loss, highlighting the benefits and limitations of both prescription and over-the-counter devices. The research suggests that personalized fitting and follow-up care are crucial for optimal outcomes.
Researchers reconstructed the most detailed map of molecular machines that carried out life's functions in an ancient ancestor, revealing hundreds of new genes associated with human diseases. The study confirmed links between three rare disorders and identified potential targets for treating other diseases.
A new study projects that climate change will significantly increase the risk of heat-related cardiovascular disease in the US by 2050. The Pacific Northwest and Southern/Midwestern states are expected to experience the highest and steepest increases, respectively. Targeted interventions for vulnerable communities are crucial to mitiga...
Researchers have developed a cell-based delivery platform that uses encapsulated engineered cells to secrete cytokines directly within the wound environment, supporting accelerated wound healing in rodent and porcine excisional wound models. The approach is designed to maintain therapeutic levels of signaling molecules at the wound site.
A comprehensive long-term study has demonstrated the efficacy of molecular blood tests in influencing leukemia course. The study found that early intervention based on molecular markers can have a significant impact on disease progression.
A new study published in JAMA Network Open found that approximately 16% of patients with COVID-19 developed long COVID, translating to over 18 million Americans. The study used a novel AI algorithm to identify cases undetected by existing diagnostic systems.
A study by Harvard T.H. Chan School of Public Health found that gut microbiome alterations persist even after adenoma removal, increasing the risk of colorectal cancer. The researchers discovered that diet and physical activity were closely tied to CRC-associated gut microbes, suggesting lifestyle habits may contribute to sustained risk.
A recent study using motion-capture and particle image velocimetry reveals that the flutter kick generates three-dimensional vortex structures contributing to forward propulsion. The alternating leg movements also produce asymmetric vortices, generating rolling and yaw moments that stabilize body posture during swimming.
A new study published in Nutrition Research analyzed evidence from thousands of people and found that natural trans fats in dairy do not increase the risk of heart disease or type 2 diabetes. The research provides clarity on trans fat labelling policies, giving consumers reassurance about the safety of dairy foods.
Researchers highlight the promise of using human monoclonal antibodies to treat patients more effectively and tackle antimicrobial resistance. mAbs can be designed to target only the disease-causing bacteria, thereby protecting the microbiome.
A study published in Nature suggests that individuals at the extremes of certain traits, such as cholesterol and blood glucose, are more likely to have rare genetic variants with larger effects. This discovery may lead to better preventive care and treatments for those with extreme trait values.
Research using EEG reveals that caffeine can reduce slow-wave activity and shift brain patterns towards wakefulness, even if sleep duration appears normal. This can lead to a vicious cycle of fatigue and poorer sleep quality, highlighting the need for personalized approaches to caffeine consumption.
Children's Hospital Colorado has pioneered a groundbreaking approach to treating cystic fibrosis before birth, resulting in reduced NICU stays and improved pancreatic function. The pioneering care model uses ETI therapy to improve lung health and offers seamless continuation of treatment after birth through breast milk.
Researchers found a clear spike in fungal microfossils following the asteroid impact that wiped out the dinosaurs 66 million years ago. This global event, occurring tens of thousands of years before the extinction, suggests that volcanism may have contributed to the mass extinctions in that period.
A new antifungal aqueous suspension has been developed by Universitat Jaume I and GEA Biotechnology to prevent fungal infections in crops and fruit. The formulation, based on biodegradable chitosan microcapsules, offers a sustainable alternative to conventional synthetic fungicides.
Two projects, BOOST-HP and BIONIC, use machine learning to analyze large datasets of medication exposure and outcomes. The findings highlight the need for more data and cautious design of machine learning models to accurately assess potential links between medications and pregnant women.
Murnane recognized for pioneering ultrafast laser technology and XUV science, as well as exceptional mentorship and leadership. She has made seminal contributions to the field of optics with over 25 years of international leadership.
Researchers discovered that degrading mutant KRAS protein leads to greater lung cancer regression and more durable antitumor responses than conventional inhibitors. The study also identifies resistance mechanisms distinct from those previously described, offering new insights into targeted protein degradation therapies.
A research team found that tropical forest plants increase root carbon exudation to stimulate phosphatase activity, mineralize organic P, and release organic acids to dissolve mineral-bound P. This adaptation helps alleviate P limitation under long-term N enrichment, sustaining productivity.
Research from Washington State University found that graphic anti-smoking ads can lead smokers to vape instead of quit due to the lack of comparable health warnings on e-cigarettes. The study suggests that consumers may perceive e-cigarettes as a safer option when exposed to vivid images of smoking's health consequences.
A new viewpoint article highlights the risk of AI 'collusion' with unreliable human input in mental health settings. The author argues that clinical expertise should be included when designing training data and evaluating AI systems to strengthen safeguards.
Researchers at Binghamton University developed a system that enables users to monitor real plants in real-time using virtual reality. This technology makes farming more accessible for older adults and people with disabilities, allowing them to observe plants without physically being present.
Researchers at UC San Diego have identified a naturally occurring peptide that significantly slows melanoma growth, reduces tumor spread, and restores sensitivity in drug-resistant cells. The findings suggest CST could serve as the foundation for a new class of peptide-based therapies against advanced and therapy-resistant melanoma.
A team has developed a highly efficient glass screen that converts X-rays into visible light, capturing diagnostic images with less radiation. The new 'quantum glass' can be molded into curved shapes, enabling the creation of X-ray imaging systems that curve to fit a person's anatomy.
The National Comprehensive Cancer Network (NCCN) has launched a new free service providing weekly email updates on changes to evidence-based guidelines for cancer prevention, screening, treatment, and supportive care. The service aims to keep healthcare providers up-to-date with rapidly evolving evidence-based recommendations.
The American Cancer Society has updated its guidelines for colorectal cancer screening, introducing blood-based and at-home stool testing options to increase accessibility. The new recommendations aim to close the screening gap and detect more cancers at an earlier stage, with a focus on underserved populations.
Researchers found that impaired virtual reality path integration was closely tied to brain structure and biomarkers associated with neurodegeneration. This suggests that VR-based navigation errors may reveal hidden changes in the brain long before symptoms arise, making it a promising behavioral marker for preclinical Alzheimer's disease.
The American Cancer Society has endorsed two new types of stool tests and recommends limiting the use of blood tests for colorectal cancer screening. The guidelines aim to encourage people to get screened while improving detection rates.
The Mount Sinai Health System has opened the Carolyn Rowan Center for Women’s Health and Wellness, which brings together multidisciplinary clinical expertise, structured care pathways, and leading-edge research to deliver personalized, comprehensive care for women. The Center offers guided multi-visit experiences and coordinated care o...
Researchers at the University of Rochester developed a solar-thermal desalination process that produces fresh water in an energy-efficient way, eliminating brine and requiring no chemical additives. The technology extracts nearly 100% of salts in solid form, producing table salt and precious minerals like lithium.
A new study found that adults with higher Life's Essential 8 scores were nearly half as likely to be hospitalized or die from COVID-19. Better heart health was linked to a lower risk of severe COVID-19 infection, suggesting that a healthy lifestyle may help prepare the body for real-life stress tests like infectious diseases.
A new study published in the Journal of the American Heart Association found that adults with better Life's Essential 8 scores had lower odds of becoming severely ill or dying from COVID-19. The research suggests that having a healthy heart helps prepare the body for real-life stress tests, such as infectious diseases like COVID-19.
A European team has successfully observed the 'quantum metric' in a three-dimensional topological insulator, a unique geometric property that enables free electrical conductivity on its surface. This breakthrough could lead to better control of next-generation materials and pave the way for faster data transfer and superconductivity.
A new ISGlobal study found that nearly 30% of health and social care workers in Europe were exposed to at least one cancer risk factor, with radiation, diesel engine exhaust emissions, and certain chemicals being the main risks. The study highlights the need for prevention strategies tailored to real working conditions in this field.
Researchers reveal the intricate structure of the Themis-Grb2 complex, a crucial signaling hub in the immune system. The discovery provides important insights into T cell development and may support new approaches for treating immune-related diseases.
The FutuRaM project mapped Europe's 'urban mine', revealing a vast reservoir of metals and minerals essential for clean energy, digital technologies, and modern industry. By 2050, recovery systems could enable the EU to recover between 4.1 and 5.7 million tonnes of critical raw materials annually.
A new study found that participating in awe-inspiring natural phenomena, like a solar eclipse, increases people's identification with science and sense of belonging. The researchers also discovered that awe plays a powerful role in this process.
Researchers develop transparent oxide glass with Young's modulus exceeding 130 GPa without chemical strengthening, opening new industrial opportunities for applications in electronic devices and optical components. The innovative material can be produced using scalable industrial techniques.
A new report from Stockholm Environment Institute challenges the notion that industrial insect farming is a climate solution, citing varying environmental performance depending on production systems and energy use. The sector faces financial headwinds and regulatory barriers limit its potential for low-impact production.
Researchers found that a high arm slot and torso tilt put the most demand on the UCL, but make mechanical changes could help pitchers reduce injury risk. The study reveals that controlled pitching delivery can minimize elbow stress and produce lower speeds.
Climate change is likely to spread chikungunya virus into temperate regions like northeastern North America, central Europe, and East Asia, with the Asian tiger mosquito playing a key role in transmission. Public health officials should prepare by tracking mosquitoes, training doctors, and strengthening control measures by 2040.
The German Federal Institute for Risk Assessment presents a strategic research agenda for safe advanced materials, covering areas like data collection and state-of-the-art laboratories equipment. The initiative aims to inform policy makers and innovators on regulatory relevant research needs for safer materials.
Artificial intelligence can bridge the gap between rich multi-scale data generated by modern exercise biomedicine and urgent clinical need for tailored exercise prescriptions. Four key AI modeling paradigms, including time series learning, multimodal fusion, causal inference, and reinforcement learning, are examined.
Researchers at Stanford University found that electrical pulses can significantly extend the lifespan of sea squirts by rejuvenating their stem cells. The treatment causes a "reboot and rebound" of gene activity, similar to effects observed in humans after stress and exercise, leading to improved health and longevity.
Researchers at KAIST have developed PAVAS, an AI technology that generates realistic sound effects in videos based on the physical properties of objects. The technology analyzes movement and collision characteristics to produce more immersive audio experiences.
A new study from the University of Miami Miller School of Medicine suggests that machine learning models using patient-reported outcomes and clinical data can forecast unplanned health care use and elevated symptom burden in cancer survivors. The research offers a potential pathway toward more proactive, personalized survivorship care.
Researchers discovered that plant stomata orientation is influenced by both cell shape and mechanical stress. In Arabidopsis thaliana, stomatal divisions tend to align with the long axis of the cell but can be altered by mechanical stress, particularly on the adaxial side where growth rates differ.
A review of nearly 50,000 patients found significantly higher mortality rates for community-acquired pneumonia in intensive care units of middle-income countries compared to high-income countries. The study highlights major inequalities in outcomes and underscores the need for improved healthcare access and quality.
A new screening tool tests for microbial metabolites in urine to identify children at risk for autism, with 90% sensitivity and 100% specificity. The test may guide more targeted interventions, including approaches to restore a healthy gut microbiome.