A study of 635 men found that radiation therapy significantly prolongs survival in those with recurrent prostate cancer, particularly those with rapidly growing tumors. This breakthrough suggests that radiation can be a life-extending treatment option for these patients.
A new study by The Endocrine Society reveals that low testosterone may cause health problems leading to erectile dysfunction, metabolic syndrome, and cardiovascular disease. Researchers found that 18.3% of men with erectile dysfunction had undetected testosterone deficiency.
A new nomogram model predicts the probability of renal cancer recurrence 12 years after initial treatment, using tumor and patient characteristics to maximize predictive accuracy. The model helps clinicians counsel patients and customize treatment recommendations for individual patients.
Researchers presented promising results for OncoVEXGM-CSF in treating metastatic melanoma, achieving treatment success in 32% of patients. Additionally, studies on robotic prostatectomy found excellent cancer control outcomes with disease-free survival rates at 21 months. The association between obesity and microvascular invasion was a...
A team of researchers at Thomas Jefferson University and Ohio State University Medical Center has identified a specific gene signature profile associated with metastasis. This signature is composed mainly of overexpressed microRNAs and may represent a new approach for diagnosing metastatic cancer.
Researchers at Thomas Jefferson University have developed a new ultrasound technique that targets areas of increased blood flow in the prostate gland, significantly reducing the number of unnecessary biopsies. The study found that targeted biopsies were twice as likely to detect cancer compared to conventional methods.
A team of international experts from 10 countries developed the first evidence-based definition of lifelong premature ejaculation, aiding future diagnosis and treatment. The definition combines three key factors: early ejaculation nearly every time, inability to delay ejaculation, and negative personal consequences.
A re-analysis of PCPT data reveals that finasteride significantly reduces the incidence of prostate cancers, including higher-grade ones. The study also suggests that finasteride may suppress indolent cancers and could be useful in determining tumor aggressiveness.
A national study has found that the majority of kidney cancers are now diagnosed at an earlier stage, with a significant increase in stage I tumors and improved overall survival rates. The study attributes this trend to the increased use of medical imaging, which leads to the detection of smaller, non-symptomatic tumors.
Researchers found a 27% reduced incidence of prostate cancer in mice on a low-fat diet compared to those on a Western-style diet. The study suggests that lowering dietary fat intake may slow the growth of precancerous cells and prevent prostate cancer development.
A population-based study of over 5,000 men and women found that obesity and unhealthy lifestyles are associated with a larger number of urinary problems. Women who have had hysterectomies and men who have undergone prostate or bladder surgery also face an elevated risk. The study highlights the importance of considering social economic...
Researchers found that vitamin D increases expression of a key enzyme, protecting prostate cells from damage and injuries leading to cancer. Vitamin D also reduces reactive oxygen species, which can damage DNA and play a role in aging or causing cancer.
A prostate cancer screening program introduced in the Tyrol region of Austria led to a significant reduction in deaths from the disease, with a 54% decline by 2005. The program's success can be attributed to early detection and effective treatment, which has improved patient outcomes.
A new study confirms that black women have less urinary incontinence than white women, but when they do develop it, the condition tends to be more severe. The study also found that black women experience 'urge incontinence' twice as often as white women.
A study by researchers at Duke University Medical Center found that exercising mice grew prostate tumors twice as fast as non-exercising mice, potentially leading to improved drug delivery models for cancer treatment. The exercise may increase blood flow to tumors, allowing for better distribution of medicine.
A recent study published in BJU International found that kidney cancer deaths in Europe have declined by 13% for men and 17% for women between 1992 and 2002, with the largest reductions seen in Austria and Germany. However, the study also reveals significant variations in mortality rates across different countries.
A new study published in Radiology found that MRI detection of extracapsular extension is an important factor in determining outcome for men scheduled to undergo radiation therapy. Patients with substantial extracapsular spread are more likely to experience recurrence and spread of their cancers.
Researchers found that only about 45% of cases used tumor markers AFP and HCG, with all three markers measured in just 16% of the time. This suggests low usage rates despite the importance of tumor markers in showing patient response to treatment and disease recurrence.
A new blood biomarker has been discovered that enables accurate prediction of prostate cancer metastasis. The biomarker, endoglin, measures plasma levels associated with an increased risk of cancer spread into regional lymph nodes. Adding this marker to current methods improves accuracy from 89.4% to 97.8%.
Researchers have discovered that chewing gum stimulates smooth muscle fibers and salivary gland secretion, aiding in bowel movement recovery after surgery. The study involved 102 patients undergoing gastrointestinal surgery, with those who chewed gum experiencing faster recovery times.
A five-year grant aims to uncover the genetic mechanism behind increased sensitivity to estrogen due to low-dose BPA exposure, which may predispose men to prostate cancer later in life. The study will use human prostate-like structures and animal models to characterize dose-response and gene modifications.
Researchers at UCLA's Jonsson Cancer Center found that hormone refractory prostate cancers are more invasive and likely to spread to other organs than androgen-dependent cancers. The study suggests that blocking overexpression of the androgen receptor could prevent cancer spread.
Researchers found that mildly obese men's PSA scores were fourteen percent lower than normal-weight men, while moderately and severely obese men had 29 percent lower PSA values. The study highlights the need to reconsider PSA threshold values for heavier patients to ensure timely diagnosis.
Researchers at Henry Ford Hospital are conducting a phase III clinical trial to determine the effectiveness of gene therapy in combination with radiation therapy for patients with intermediate risk prostate cancer. The trial aims to improve patient outcomes by delaying hormone therapy, which can have severe side effects.
Researchers analyzed data from the National Cancer Institute's Prostate Cancer Prevention Trial, showing that finasteride reduces prostate cancer risk by 25% but also causes side effects like impotence. The study encourages men to consider both benefits and drawbacks before taking the drug to prevent prostate cancer.
Researchers at UT Southwestern Medical Center found that hormonal components in over-the-counter dietary supplements can stimulate cancer-cell growth and make anti-cancer drugs less effective. The study's findings highlight the need for patients to inform their doctors about any herbal or hormonal supplements they are taking.
A new Mayo Clinic study found that removing the entire kidney from younger patients with small kidney tumors may lead to decreased overall survival. In contrast, partial nephrectomy resulted in a 10-year overall survival rate of 93%. The study's findings highlight the importance of considering long-term health consequences for patients...
A large-scale randomized trial of nearly 4,500 men found no significant differences in sexual satisfaction and performance between circumcised and non-circumcised individuals. The study's findings support the use of circumcision as an effective way to reduce HIV transmission
Researchers found that a short course of hormonal therapy before and with radiation therapy slowed cancer growth by up to eight years, particularly the development of bone metastases. This delayed cancer progression increased survival rates among older men with potentially aggressive prostate cancer.
Researchers will focus on finding medical reasons for the constant urge to urinate, which affects one in six adults over 40 and can cause distress and anxiety. The team aims to develop better ways to identify, manage and treat this common condition.
A UTSouthwestern urologist has used botulinum toxin A (Botox) injections to treat involuntary bladder contractions in quadriplegic patients. The treatment has shown promising results, enabling patients to regain control of their bladders and improve their quality of life.
A retrospective case note review of 1000 patients found that 8.7% experienced at least one adverse event, with many preventable, and led to extended hospital stays or permanent disability
Researchers identified two proteins, hnRNP-H1 and SAFB-2, as potential biomarkers for disease screening in African-American men. These proteins are involved in the growth of tumor cells and may play a role in hormone-related prostate cancer progression.
A study of over 300 live kidney donors found that they had good kidney function and tended to suffer a lower incidence of high blood pressure, diabetes, and heart-related deaths compared to the general population. Donors reported high satisfaction rates and would strongly encourage others to become donors if needed.
Researchers at UC Davis identified a cellular pathway involving microRNA miR-125b that contributes to the progression of prostate cancer. The discovery provides a potential target for reducing cancer deaths among American men.
A new study led by Duke Prostate Center researchers found that obese men may be missing cancers because the blood marker used to detect prostate cancer can be diluted in their bodies. The concentration of prostate-specific antigen (PSA) in the blood is lower in obese men due to increased blood volume.
The AUA and EAU have released new guidelines for managing ureteral calculi, recommending updated treatment options such as ureteroscopy (URS) for all locations and sizes of stones. The guidelines also identify areas for future research to improve patient outcomes.
A low-carb diet may help stunt prostate tumor growth by reducing insulin production, according to a new study. The study found that mice on a low-carb diet had longer survival and smaller tumors than those on other diets.
Varicocele removal significantly improves testosterone levels in over two-thirds of men, leading to improved fertility and reduced symptoms of andropause such as low sex drive and depression.
A study of over 60,000 Danish men found that prostate cancer increases the risk of hip fractures by eight times in men aged 50-65. The researchers discovered that prostate cancer made men 1.8 times more likely to suffer a fracture and 3.7 times as likely to suffer from a hip fracture.
Researchers have discovered new small molecules that can prevent prostate cancer cells from turning off normal genes by blocking the action of a methyl-CpG binding protein. This breakthrough has significant implications for the development of targeted therapies for prostate and other cancers.
A study by Johns Hopkins researchers found that standard androgen deprivation therapy for prostate cancer may increase the production of nestin, a protein that promotes cell migration and metastasis. The therapy is effective in slowing tumor growth but may inadvertently encourage cancer cells to spread throughout the body.
A recent study of over 200 patients found that 88% were happy with their surgery at the first post-operative clinic visit. Despite complications, 76% were satisfied with the cosmetic result and 80% said the surgery met their expectations. Common issues included vaginal hair growth, prolapse, and necrosis.
UCSF researchers have developed a new method to generate embryonic stem cells, eliminating the need for a foreign 'drug resistance' gene. This breakthrough accelerates research on disease development and patient-specific therapies.
Researchers discovered B7-H3, an immune molecule that predicts prostate cancer progression and recurrence after surgery. The biomarker can help individualize treatment plans for patients.
Dr. John McConnell receives the 2007 Eugene Fuller Triennial Prostate Award for his innovative research studies on prostate enlargement and leadership in developing a multidisciplinary program at UT Southwestern. His research findings include combining alpha-blocking drugs to effectively treat benign prostatic hyperplasia.
A new imaging technique using Indocyanine Green (ICG) dye helps surgeons precisely remove cancerous tumors from the kidney while sparing as much healthy tissue as possible. This innovation allows for more effective treatment and better patient outcomes.
A trial found that circulating tumor cells in the blood of patients with metastatic prostate cancer can predict how well they will respond to chemotherapy. Patients with more than five tumor cells per blood sample had a worse prognosis, while those whose CTC number went down fared better.
A study from the University of Chicago Medical Center found that African-American men radically underestimate the likelihood of a cancer diagnosis after a needle biopsy for suspected prostate cancer. This underestimation can lead to delayed diagnoses and poorer outcomes.
A new study reveals that patients with localized prostate cancer are more likely to receive surgery if they see a urologist, while those who see a radiation oncologist and urologist tend to receive radiation therapy. The study suggests that men should seek a balanced perspective on treatment options from specialists.
A new study developed a simple marker that allows urologists to identify men at risk for high-grade prostate cancer, even after a negative initial biopsy. This finding could reduce overtreatment and unnecessary biopsies while improving patient outcomes.
Researchers delivered gene therapy containing nerve growth factors to rats with erectile dysfunction, resulting in significant recovery of intracavernous pressure and systemic arterial pressure. The study suggests a long-term treatment option for erectile dysfunction without chronic drug administration.
A research review found that men worry more about their penis size than women, with average-sized penises being just as desirable. Despite this, many men experience anxiety and small penis syndrome, which can be treated with conservative approaches such as therapy and education.
Researchers at the University of Pittsburgh School of Medicine have found that Botox injections can reduce prostate size and alleviate urinary tract symptoms in men with benign prostatic hyperplasia (BPH). Up to 73% of patients experienced improved quality of life and reduced symptoms for up to a year after treatment.
Researchers have made significant breakthroughs in stem cell treatment options, including isolation of human spermatoogonial stem cells and use of autologous adipose-derived stem cells. Studies also show promise for engineered bladder tissue and muscle-derived cell injection in treating stress urinary incontinence.
A study led by researchers at the University of Pittsburgh School of Medicine found that muscle-derived stem cell injections strengthened sphincter muscles, improving bladder control and quality of life for women with stress urinary incontinence. The treatment was safe and effective, with long-term improvements observed.
A study by NIH/NIDDK found that sling surgery was more effective in achieving dryness and quality of life for women with SUI, but had higher side effects. The procedure helped significantly more women achieve stress-specific success compared to the Burch technique.
A recent study has discovered a strong hereditary component to aggressive prostate cancer, with patients carrying the 8q24 genetic marker having a higher risk of developing the disease. The marker is twice as common in African-American men, who also experience the disease at a younger age and have a higher incidence rate.
A study at the University of Pittsburgh School of Medicine found that green tea's catechins protected normal and cancerous bladder cells from inflammation. The findings suggest herbal supplements from green tea could be a treatment option for various bladder conditions.
Researchers have found that veterans exposed to Agent Orange have a 48% higher risk of prostate cancer recurrence following surgery compared to their unexposed peers. Black veterans with a history of exposure were also more likely to experience aggressive disease and rapid PSA level increases.