Scientists at Brown University and Women & Infants Hospital have made a groundbreaking discovery that could revolutionize the field of fertility treatments. They found a way to analyze the genetic material in discarded polar bodies from human egg cells, which may reveal insights into their ability to develop healthy embryos.
Scientists discovered a crater formed by a NASA-engineered collision that showed the Moon's soil contains more complex compounds than previously believed. The study found water, hydroxyl, carbon monoxide, carbon dioxide, ammonia, free sodium, and silver in the lunar regolith.
The African Successes project identifies and analyzes African successes, focusing on economic and political improvements, transparency, and freedom of press. Researchers are studying successful initiatives such as an anti-malaria campaign in Zambia and a cellphone-based money transfer system in Kenya.
Researchers will investigate the complex interactions between alcohol consumption and HIV, including brain and liver damage, adherence to antiretroviral medications, and safe sex practices. The goal is to determine whether individuals need to stop or reduce their drinking.
Researchers at Brown University and international partners have identified a potential Achilles Heel in the rare but deadly JC polyomavirus, which binds to a specific sugar molecule on brain cells. The discovery provides a powerful platform for developing new therapeutics to prevent infection.
A research team at Brown University has discovered a key chemical process involved in the development of cancer, particularly breast cancer. The study found that prolactin receptors can come together to form a structure that picks up growth factors leading to cancerous growth.
Researchers at Brown University have developed a well-defined animal model of preeclampsia, allowing for experiments to shed light on the disease's cause. A potential lab test has also been developed to diagnose the disease in people, predicting problems as early as 12 weeks into pregnancy.
Researchers at Brown University have developed a new method for converting waste vegetable oil into biodiesel fuel, using a single reaction vessel and environmentally friendly catalysts. The process is six times faster than current methods, consuming less energy and reducing the use of toxic chemicals.
Healthy adults who experienced childhood abuse or neglect may have an elevated inflammatory response to stress, increasing their risk of depression and anxiety disorders. A study found that adults with adverse childhood experiences had higher levels of inflammatory markers, such as interleukin-6, in their blood.
Brown University has granted an exclusive license to Tivorsan Pharmaceuticals for a potential treatment of Duchenne muscular dystrophy, slowing muscle damage in mice by 50 percent. The treatment, based on biglycan protein, aims to prolong boys' ability to walk without assistance and perform daily activities.
Researchers created a comprehensive catalog of large craters on the moon to study the chaotic early days of the inner solar system. The analysis suggests that larger projectiles dominated the bombardment, ending around 3.8 billion years ago.
Brown University researchers have created an artificial human ovary, enabling them to mature human eggs in a lab setting. The innovation could lead to fertility research and infertility treatments for cancer patients.
Brown University researchers have discovered the structure of three types of proteins that don't have a fixed shape, revealing how they interact with other proteins to regulate important biological processes. The findings provide new insights into the complex mechanisms underlying these proteins' functions.
A new computer system, based on a model of the human brain's visual processing, accurately identifies mouse behaviors in videos, reducing tedious data logging tasks. The open-source software is available for free and can be easily trained to work with other lab animals, increasing productivity in behavioral research.
The Institute for Computational and Experimental Research in Mathematics (ICERM) will leverage internationally recognized programs to create long-term research programs and scholarly conferences. The institute aims to solve new problems of critical importance and benefit to society through collaboration with industries.
Researchers found that epigenetic profiles of tumors had a direct association with diet, alcohol, and tumor size, providing new biomarkers for disease subtype and severity. The study's data show promise for tumor epigenetic signatures to provide more detailed tumor staging and prediction of prognosis.
The study found that Medicare-certified hospice stays in nursing homes have doubled in the last 10 years, with average treatment times increasing from 46 to 93 days. The researchers attribute this growth to increased Medicare services and reimbursement policies that incentivize longer stays.
A team from Brown University has discovered extensive glaciofluvial valleys on Mars, which were formed by running water originating from glaciers. The findings, published in Icarus, indicate that water existed on the planet as recently as several hundred million years ago.
A research team found that tropical ocean surface temperatures dropped by 1-3 degrees Celsius during each Ice Age, coinciding with the spread of ice sheets in the Northern Hemisphere. The study suggests carbon dioxide played a major role in controlling global climate patterns, beginning with the Ice Ages and continuing today.
Brown University researchers have gained new insights into graphene defects through molecular dynamic simulations. They found that oxygen atoms forming double bonds with carbon create irregular holes in the lattice. The team proposes adding hydrogen to remove impurities and heal the holes.
Researchers have developed a unique core and shell nanoparticle that uses far less platinum yet performs more efficiently and lasts longer than commercially available pure-platinum catalysts. The new catalyst generates 12 times more current than existing models, offering a promising advance in fuel-cell technology.
The Asian shore crab has found a hospitable niche in its new environment, coexisting with native species in the cobbled beach ecosystem. The cordgrass-ribbed mussel environment provides a stable habitat for the crabs, allowing them to thrive without crowding out native species.
Researchers at Brown University have found that Lake Tanganyika has experienced unprecedented warming over the last century, with surface waters reaching record highs. This warming is expected to affect fish stocks, which are crucial for millions of people in the region, and could have severe consequences for local livelihoods.
Researchers found that the brain's frontal cortex plays a key role in processing abstract knowledge, enabling individuals to adapt behaviors based on past learning. The study used fMRI to investigate how the brain achieves flexibility in solving unfamiliar problems.
A clinical study found that stroke patients can regain limb movement long after an injury through intensive therapy with specially trained personnel and newly created robotic aids. The study showed statistically significant improvements in quality of life, upper-arm function, and everyday activities.
Researchers found a new mechanism controlling peak strength in nanostructured metals by observing organized dislocation patterns in 3-D atomic simulations. The pattern, governed by nucleation, dictates the metal's strength or weakness.
Researchers at Brown University have found that echolocating bats use mental templates to differentiate between broadcast and echo signals, allowing them to minimize sound wave interference. By tweaking sound frequency, bats can create a unique template for each broadcast/echo set, enabling efficient navigation in cluttered environments.
Researchers at Brown University have identified how protein phosphatase 1 (PP1) regulates substrate proteins by binding to specific sites, increasing specificity and reducing errors. This discovery sheds light on the enzyme's critical role in various diseases, including cancer and Parkinson's disease.
A Brown University-led team discovered that massive volcanic eruptions led to a spike in atmospheric carbon dioxide, wiping out half of plant species and decimating crurotarsans. This allowed early theropods, including dinosaurs, to become dominant in the animal world.
Researchers found barnacle communities flourish in vertical-upwelling zones with strong currents, contradicting previous theories. The study's findings suggest that barnacles latch onto rock walls due to constant bouncing against rocky surfaces, ultimately leading to the formation of thriving crustacean populations.
Brown University researchers found that considering alternative possibilities can lead to better planning and decision-making. They discovered that people tend to focus on a single cause when making predictions, but not when diagnosing causes.
Researchers at Brown University have observed a quantum-level phenomenon where electrons form odd, fluctuating magnetic waves in superconducting materials. These waves are promoted by superconductivity and disappear when more magnetic energy is applied.
A study by Brown University researchers highlights the need for better decision-making in end-of-life care, particularly for hospitalized nursing home residents with advanced dementia. The study found that feeding tubes are used variably among hospitals, with larger or for-profit hospitals using them more frequently.
Researchers compiled database of 1.1 million grass species and found 18 out of 21 transition nodes between C3 and C4 grasses were linked to changes in precipitation. This discovery challenges previous understanding that warmer temperatures were the primary driver of C4 grasses' evolution.
A new study by Brown University researchers suggests that increasing insurance co-payments for routine doctor visits may actually make care more expensive. Patients with higher co-payments cut back on their doctor visits but ultimately require more expensive hospital care due to worsening illnesses.
A study published in the Journal of Vision found that outfielders catch fly balls by tracking optical acceleration, rather than predicting the ball's trajectory. The research used a virtual environment to test three major theories of fly catching, and confirmed that baseball players continuously track the ball and run forward or backwa...
A new study by Brown University finds that Hispanic elderly are more likely than whites to live in poor-quality nursing homes, facing structural problems, staffing issues, and financial trouble. The research highlights the need for better quality care and policy changes to address these disparities.
A new study by Brown University and Caltech scientists reveals how cells interact with their environment, including the force exerted on tissues as they move. The research provides the most complete assessment to date of cell movement in three dimensions.
Researchers discovered that sucker-footed bats of Madagascar use wet adhesion to attach themselves to surfaces, ruling out suction as the primary method. The finding helps scientists understand how these small creatures live in the wild and sheds light on the evolutionary relationship between two similar bat species.
Researchers from Brown University have discovered that inhibiting Sirt1 activity in the brain's hypothalamic region can help control food intake and lead to a smaller weight gain. The study suggests a potential mechanism for new obesity treatments.
Researchers at Brown University have identified a cellular mechanism that enables cells to transform their state, which could lead to new insights into diseases. The study found that a regulatory protein removes a lid from genes, allowing the cell to change its identity.
A new newborn exam, the NICU Network Neurobehavioral Scale (NNNS), has been developed to identify infants at risk of developmental problems. The exam identified five distinct neurobehavioral profiles, with poor performance linked to behavior problems, school readiness issues, and low IQ.
Two Brown University faculty members are awarded federal funding to investigate brain development in infants and children with bipolar disorder. The research aims to identify biological and behavioral markers that distinguish between full-blown and sub-syndromal bipolar disorder, which could lead to more specific diagnoses and treatment.
Researchers have observed dynamic upwelling in the underlying mantle beneath a spreading center, leading to new crust formation. This finding resolves a long-standing debate regarding the relative importance of passive and dynamic upwelling in oceanic crust creation.
Researchers found a direct connection between childhood psychological trauma and accelerated reduction in telomere size, which promotes cellular stability. Telomeres typically shorten with age, but the study shows that childhood abuse can accelerate this process.
Researchers aim to understand how the JC virus attaches to host cells, with potential treatments for progressive multifocal leukoencephalopathy (PML). The five-year grant will explore the virus's interaction with serotonin receptors in the brain.
Researchers argue that concurrency is not a major driver of the HIV epidemic in sub-Saharan Africa due to lack of conclusive evidence. They suggest that other factors are more likely to contribute to the spread of the virus, and recommend further research initiatives.
Natural killer cells help maintain a balance between T cells and the immune system, preventing over-response that can cause harm. Understanding how to keep NK cells around could lead to new treatments for patients with compromised immune systems.
A $5.2 million NIH grant will fund detailed genotyping of thousands of adults in Samoa to investigate genetic variation associated with obesity, diabetes and cardiovascular disease. The study aims to identify specific 'susceptibility' genes that may increase the risk of these conditions.
Scientists at Brown University have found evidence of water molecules on the moon's surface, with up to 1,000 parts-per-million in lunar soil. This discovery could provide a mechanism for water to reach permanently shadowed craters, opening new avenues for lunar research.