A new care model for bipolar disorder, developed by Brown University researchers, has shown promise in reducing manic episodes and improving quality of life. The team-based approach involves psychiatrists and nurses working together to manage symptoms, resulting in a significant reduction in symptoms and improved function.
Brown University physicists discover that chemical bonding and mechanical instability lead to the formation of zebra-striped patterns in microtubules. This finding provides insight into how shapes are created in living organisms.
A Brown University research team has successfully used DNA to assemble and grow complex zinc oxide nanowires, which can create light and generate electricity. The new structures have potential applications in medical diagnostics, security sensors, fiber optical networks, and computer circuits.
Researchers developed a brain-to-movement system called BrainGate, which enabled a paralyzed man to control objects using only his thoughts. The pilot clinical trial findings show that movement signals persist in the primary motor cortex long after a spinal cord injury, allowing for direct and successful control of external devices.
Researchers at Brown University have developed a technique to coat implants with zinc or titanium oxide nanosurfaces, significantly reducing bacterial growth and promoting bone growth. The new method has the potential to lead to safer, longer-lasting implants for millions of Americans undergoing joint replacements.
A new theoretical model explains how cooperation can emerge in a 'cheater's world', where self-interest typically prevails. In this model, group size plays a crucial role in the evolution of cooperation, with smaller groups allowing altruistic individuals to thrive and maintain their numbers over time.
Asteroid Itokawa's surface composition was determined by Brown University researcher Takahiro Hiroi, who linked it to LL chondrites, a common class of stony meteorites. The team also described the asteroid's diverse terrain, suggesting it may be an earlier stage of asteroid evolution and formation.
New evidence from a 430-meter sediment core reveals glaciers in the Arctic Ocean formed simultaneously with those in Antarctica, rewriting climate history. The discovery underscores the role of greenhouse gases in driving global climate change.
Researchers found that flagella in algae allow for active nutrient gathering, concentrating nutrients just ahead of the moving colony. This discovery explains how single-celled life forms can evolve into larger multicellular organisms like Volvox, a colony of up to 50,000 cells.
Researchers found that combining medical management, naltrexone, or therapy can significantly help people with alcohol disease. The study, COMBINE, included 1,383 subjects and showed that just nine 20-minute sessions with a medical professional yields good clinical results.
A new study found a strong connection between colic and postpartum depression in demographically diverse women. 19% of mothers reported moderate to severe symptoms of postpartum depression, while 8% reported their babies were difficult to console.
A new study found that branching coral Montipora capitata sharpens its plankton intake when bleached, increasing its chances of recovery. The findings indicate that any coral, regardless of shape or location, can recover if it can increase feeding.
A comprehensive mineral history of Mars reveals that conditions became increasingly dry and acidic around 3.5 billion years ago, making it an unlikely place for life to thrive. The study identifies clay-rich rocks and soil as potential targets for future lander missions.
Researchers found that a 'dead zone' summer in Narragansett Bay led to the death of approximately 4.5 billion mussels, with filtering capacity dropping by 75 percent within weeks. The loss of such a foundation species has lasting effects on the ecosystem.
The study found a pattern of steady cooling in the EEP over 5 million years, with temperatures dropping by roughly one degree Celsius every million years. The research suggests that ocean regions near Antarctica were the main driver of EEP cooling, contradicting previous theories about rapid glacier growth in high northern latitudes.
Brown University professors and USC colleagues find a molecule spinning at 270 trillion rotations per minute, annihilating friction. The phenomenon challenges old laws of physics, suggesting molecules can move energy without slowing down.
A team of Brown University chemists has developed a new class of molecules that exhibit fast and efficient catalytic properties, making them suitable for use in the pharmaceutical industry. The compounds also show promise for storing hydrogen and other gases, which could be used to generate clean energy.
Researchers have identified a mutant protein as a key culprit molecule in causing heart disease, including atherosclerosis, which is a leading cause of heart attacks and strokes. The study also sheds light on the progression of progeria, a rare genetic condition that accelerates aging in children.
Biologists at Brown University and the University of California–Berkeley have discovered a critical role for two proteins – TAF4b and c-Jun – in the growth and nurturing of granulosa cells that surround eggs. The finding provides important new information about fertility and may lead to better in-vitro fertilization therapies.
A team of scientists from Delft University of Technology, Brown University, and the University of Alabama have successfully created a 'spin triplet' supercurrent through a unique ferromagnet. The discovery breaks quantum physics theory by showing that electrons can exist in three quantum states inside the magnet.
The landmark COBY study found bipolar disorder in children and teens progresses differently than in adults, with more frequent mood swings and longer symptom duration. Children and teens often switch between different illness sub-types during the course of follow-up.
Researchers have found that the number of senescent cells increases exponentially with age, with TIF-positive cells making up about 4% of connective tissue in young monkeys and 20% in older ones. The study confirms the importance of telomeres in aging and suggests a strong link between aging cells and body.
The study provides key insights into the composition of comets, with three pockets of thin ice detected on Tempel 1. The surface ice appears to have been exposed over time through geologically active jets, revealing an abundance of organic matter and water.
A demographic analysis reveals significant disparities between damaged areas and undamaged zones, with black and poor residents facing greater odds of harm. The findings have implications for the future of the Gulf region, particularly in New Orleans.
Scientists have successfully engineered lactic acid bacteria to produce a viricide that disables HIV, paving the way for potential use as a microbicide. The genetically modified bacteria will be tested in monkeys this summer, with human trials planned for three years.
Researchers found that tropical glaciers on Mars were formed from snow brought from the polar regions, similar to Earth's mountainous regions. This discovery sheds light on past climate changes on Mars and potential pockets of ice scattered across the planet.
Intrinsically photosensitive retinal ganglion cells (ipRGCs) adapt to lighting conditions, sending signals about overall brightness to the brain. This adaptation allows ipRGCs to regulate pupil size and circadian rhythms.
Researchers found that electrical synapses in the thalamic reticular nucleus can undergo long-term changes, influencing brain rhythms and behavioral states. The study provides new insights into neural plasticity and its role in regulating sleep, wakefulness, and other critical brain functions.
Research reveals that drought-stressed soils create an environment conducive to the spread of fungal disease by predatory periwinkles, which graze on cordgrass. This top-down approach to salt marsh ecology challenges long-held assumptions about the main causes of marsh die-off.
Brown University researchers have created a directly pumped silicon laser by altering its atomic structure using nanoscale drilling. The achievement opens up new possibilities for the electronics and communications industries, enabling faster and more powerful computers or fiber optic networks.
Researchers at Brown University have discovered that reducing p53 protein activity in neurons can increase lifespan in fruit flies by 58%, a finding that suggests a potential mechanism for slowing aging through the caloric restriction pathway.
Researchers investigate which nanomaterial sizes, shapes, compounds, and coatings harm or kill cells. The aim is to develop non-toxic types using 'green' nanomaterials, addressing growing concerns about nanoparticle health impacts.
The NSF grant supports research into thin films, complex multiphase materials, and human cell adhesion. The center aims to develop more durable materials and create better medical tests and treatments.
A new study found that sleep restriction significantly affects students' academic performance, attention, and behavior. Teachers rated students with less than eight hours of sleep as having the most trouble recalling material and paying attention.
Brown University has received a five-year, $11-million NIH COBRE award to explore how cancer cells develop from normal cells. The grant will support research on DNA damage, cell growth, and hormone signaling, with the goal of designing more effective prevention measures or treatment methods.
The Digital Mammographic Imaging Screening Trial found that digital mammography is as good as film mammography in detecting breast cancer, but may be better for younger women. The study analyzed data from 49,528 women and provides some of the best data gathered on mammogram diagnostic accuracy.
Researchers found a dramatic change in electrical conductivity at 60 kilometers below the ocean floor, with sound waves traveling rapidly above and slowly below. This discovery sheds new light on the process of forming oceanic crust at mid-ocean ridges.
Researchers discovered that prions can rapidly 'remodel' good protein into bad, shedding important light on the molecular machinery behind infectious brain diseases. This process may also help explain the progression of Alzheimer's, Parkinson's and Huntington's diseases.
A new JAMA study compares sleep deprivation to alcohol ingestion and shows that long work hours impair young doctors' cognitive function. The researchers found that residents who worked extended hours performed similarly to those with a blood alcohol concentration above the legal limit.
The Deep Impact mission revealed several dozen impact craters on Comet Tempel 1, with a powdery layer tens of meters deep. The comet's surface is composed of a fine-grained, loosely glued layer of organic powder and ice, sparking new questions about its composition and the formation of the solar system.
Researchers at Brown University have solved a crucial part of the SAP97 protein's structure, allowing them to develop a molecule that can inhibit it. This breakthrough could lead to effective treatments for cardiac and neurological diseases, including learning and memory disorders and drug addiction.
A graduate student's seismic study has found a sharp dividing line between the lithosphere and asthenosphere, contradicting the idea that the transition is gradual. The research suggests water or partly molten rock must be present in the asthenosphere to cause such an abrupt change.
A Brown University geologist is part of a joint space mission to study a comet's composition. The Deep Impact mission will provide a first-ever look inside a comet when an impactor hits Tempel 1, helping scientists understand how comets shaped the solar system.
Researchers discovered that mid-sized nanomaterials (27-30 nm) are optimal for cellular entry. This knowledge can help design drugs to keep viruses out and molecules to enter cells safely. The study's findings have broad implications for developing gene and drug delivery tools.
A Brown University and Harvard Medical School team has revealed the crystal structure of λ-integrase, a protein responsible for site-specific recombination in lambda virus. The findings provide a major leap in understanding mobile DNA, with implications for studying viral infections and gene editing.
Chronic drowsiness in teens can be a sign of an underlying sleep disorder, according to a new report. The study highlights the importance of rigorous pediatric sleep histories to diagnose potential conditions.
A new tool for tracing human gene connections has been developed, enabling the study of complex systems like power grids and neural networks. The research used a novel approach to analyze gene activity in response to c-Myc activation, revealing over 1,000 genes significantly altered by the protein.
Brown University has been awarded a four-year, $11.5-million grant to conduct research on hazardous waste and develop tools to remove it. The project aims to identify health threats posed by contaminated sites and create safe remediation devices.
Researchers discovered a universal cellular mechanism that helps cells release excess water, shedding light on kidney function and potential applications to type 1 diabetes and cancer. This finding highlights the importance of vesicle insertion and phosphorylation in regulating cellular transport.
Recent Martian glaciers and volcanoes suggest ice-rich movement and climate change, with evidence of a major eruption over 350,000 years ago. This new research challenges the traditional view of Mars' geological history and provides fresh insights into the planet's dynamic evolution.