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California Institute of Technology


Do you hear what I hear?

Researchers identified how and where the brain processes frequency-modulated sound signals, which are crucial for understanding language and speech. The study found that these signals begin in the midbrain region of the brain, a surprising discovery that could help with hearing-related disorders.

Looking at the man in the moon

Caltech researchers found that the man in the moon's face is not just a coincidence, but rather a result of the moon's slowed-down rotation rate. The side with the man facing Earth had about two-to-one odds of being visible due to the dissipation rate of the moon's rotational energy.

Plasmas torn apart

Researchers Auna Moser and Paul Bellan observed a surprising phenomenon in lab experiments that provides clues to the origin of solar flares. The discovery reveals a connection between kink instability and Rayleigh-Taylor instability, which are two distinct phenomena occurring at different scales.

Making sense of sensory connections

Researchers at Caltech explored the brains of insects to understand how sensory connections form new and specific memories. They identified a mechanism involving transient synchronization between pairs of connected neurons, known as spike-timing dependent plasticity, which makes connections sensitive to internal rewards.

Caltech chemists devise chemical reaction that holds promise for new drug development

A team of Caltech researchers has developed a method for synthesizing nitrogen-containing heterocycles, a subclass of organic compounds that could lead to new pharmaceuticals and natural products. The reaction enables chemists to create complex structures with high selectivity, solving a long-standing challenge in medicinal chemistry.

SourceCalifornia Institute of Technology·JournalNature Chemistry·DateJan 12, 2012

Switching senses

Researchers at Caltech found that leeches rely on two distinct methods to detect prey: hairs detecting water disturbances and simple eyes picking up passing shadows. In adulthood, the preference shifts to using water disturbances alone.

SourceCalifornia Institute of Technology·JournalJournal of Experimental Biology·DateNov 1, 2011

Caltech researchers increase the potency of HIV-battling proteins

Researchers at Caltech have developed a new, more potent form of the HIV-fighting protein cyanovirin-N by linking two proteins together. The engineered protein, called CVN2L0, is 18 times more effective at preventing infection than the naturally occurring single protein and neutralizes all 33 subtypes of HIV tested against it.

SourceCalifornia Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJul 28, 2011

Sharper, deeper, faster

A novel imaging technique combines high resolution, high penetration depth, and high imaging speed to capture detailed information from live biological samples without damaging them. The technique uses two-photon excitation in sheet-illumination mode, enabling fast imaging speed and reducing light-induced damage.

SourceCalifornia Institute of Technology·JournalNature Methods·DateJul 25, 2011

Wind-turbine placement produces tenfold power increase, Caltech researchers say

Researchers at California Institute of Technology have discovered that optimizing wind turbine placement on a given plot of land can increase power output by an order of magnitude. By positioning turbines in close proximity and using vertical-axis wind turbines, the team found that energy loss due to aerodynamic interference between ne...

SourceCalifornia Institute of Technology·JournalJournal of Renewable and Sustainable Energy·DateJul 13, 2011

Going with the flow: Caltech researchers find compaction bands in sandstone are permeable

Researchers have discovered that compaction bands in sandstone are more permeable than previously believed, which could significantly improve the development of hydraulic fracturing and CO2 sequestration technologies. This finding was made possible by advanced imaging techniques and multiscale computational models.

SourceCalifornia Institute of Technology·JournalGeophysical Research Letters·DateJun 6, 2011

From pre-gut cells to glory

A research team at Caltech has outlined exactly how specific sets of cells in sea-urchin embryos differentiate to become the endoderm, the early domain of the embryo that eventually forms the gut. They found that certain regulatory genes are expressed in the cells of each domain and that this process is dynamic, with gene expression ch...

Caltech researchers release first large observational study of 9.0 Tohoku-Oki earthquake

The study reveals the spatial compactness of the event, with a 250-kilometer-long fault experiencing significant slip, and high- and low-frequency seismic waves coming from different areas of the fault. This information will help scientists improve infrastructure and prevent loss of life through better application of seismological data.