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Cell Press


The ISSCR introduces “checklist” to promote global best practices for human stem cell research

The International Society for Stem Cell Research (ISSCR) has introduced a 'checklist' to promote global best practices for human stem cell research. The checklist aims to increase transparency and clarity in the reporting of key quality control measures, enabling authors to disclose critical experimental details.

SourceCell Press·JournalStem Cell Reports·TypeCommentary/editorial·DateSep 14, 2023

“Dormant” HIV produces RNA and proteins during anti-retroviral therapy

Researchers found that a subset of HIV-infected cells produce viral RNA and proteins during anti-retroviral therapy, which may impact patients' immune responses. The study suggests that these non-functional viral pieces can stimulate an immune response, potentially leading to inflammation and negative consequences for treated individuals.

SourceCell Press·JournalCell Host & Microbe·TypeObservational study·DateSep 13, 2023

Invasive red fire ants confirmed in Europe for the first time

Researchers confirm invasive red fire ant species Solenopsis invicta has established itself in Sicily, with potential to spread across Europe due to climate change. Urban areas are particularly at risk, and the team plans a multi-year treatment plan to eradicate nests and monitor the ants' spread.

SourceCell Press·JournalCurrent Biology·TypeObservational study·DateSep 11, 2023

Blood-brain barrier governs ant behavior by altering hormone levels

Researchers discovered that the blood-brain barrier in carpenter ants produces a hormone-degrading enzyme, Juvenile hormone esterase (Jhe), which controls JH3 hormone levels in the brain, affecting behavior. Manipulating Jhe levels can reprogram ant castes and even change food-seeking behavior in fruit flies.

SourceCell Press·JournalCell·TypeExperimental study·DateSep 7, 2023

Researchers grow embryonic humanized kidneys inside pigs for 28 days

Scientists have created chimeric embryos containing a combination of human and pig cells, which developed into structurally normal kidneys with 50-60% human cells. The researchers successfully grew humanized organs inside pigs, offering new possibilities for studying human development and developmental diseases.

SourceCell Press·JournalCell Stem Cell·TypeExperimental study·DateSep 7, 2023

Resistant starch supplement reduces liver triglycerides in people with fatty liver disease

A 4-month randomized controlled trial found that daily intake of resistant starch can lower liver triglycerides and liver enzymes associated with liver injury and inflammation. The treatment group had a different microbiota composition and functionality compared to the control group, leading to improved liver conditions.

SourceCell Press·JournalCell Metabolism·TypeRandomized controlled/clinical trial·DateSep 5, 2023

Inhalable molecules neutralize SARS-CoV-2 in mice

Researchers at Affilogic developed nanofitins that inhibit SARS-CoV-2 by binding to its spike proteins, demonstrating quick reach and clearance of the lungs. The technology has potential for treating other infectious respiratory diseases with lower costs and higher accessibility.

SourceCell Press·JournalMolecular Therapy·TypeExperimental study·DateAug 30, 2023

CRISPR-Cas3 gene editing system restores dystrophin function in stem cells derived from patients with Duchenne muscular dystrophy

A CRISPR-Cas3 system has restored dystrophin protein function in induced pluripotent stem cells from patients with Duchenne muscular dystrophy. The approach uses a dual CRISPR RNA method to remove large sections of the dystrophin gene, yielding truncated but still functional proteins for various mutation patterns.

SourceCell Press·JournalStem Cell Reports·TypeExperimental study·DateAug 24, 2023

Noncoding DNA explains a majority of the heritability of dairy cattle traits, like milk production and fertility

A study published in Cell Genomics reveals that noncoding DNA accounts for 69% of the heritability of dairy cattle traits, including milk production and fertility. This breakthrough could improve the efficiency of agricultural breeding programs and provide a new model system for future studies in humans and other animals.

SourceCell Press·JournalCell Genomics·TypeExperimental study·DateAug 23, 2023

With advances in in vitro models, group proposes refined legal definition of an embryo

A group of biologists and ethicists suggest adding clarity to ongoing research using embryo models to refine the legal definition of human embryos. They propose a new definition that focuses on what an embryo can become rather than how it came to be, allowing for improved evaluation of models and potential future recognition as embryos.

SourceCell Press·JournalCell·TypeCommentary/editorial·DateAug 17, 2023

Malaria vaccine candidate appears safe and produces promising immune response in a cohort of Tanzanian infants

A new malaria vaccine candidate has shown promising results in a cohort of Tanzanian infants, with substantial anti-RH5 immune responses achieved safely through vaccination. The vaccine targets the RH5 protein used by the malaria pathogen to invade red blood cells, providing a second line of defense against disease.

SourceCell Press·JournalMed·TypeExperimental study·DateAug 11, 2023

A roadmap to help AI technologies speak African languages

Researchers in Africa have developed a roadmap to create better AI-driven tools for African languages, addressing the limited availability of language data. The study identifies key players and themes to consider in designing effective language tools, including writers, linguists, software engineers, and entrepreneurs.

SourceCell Press·JournalPatterns·TypeSurvey·DateAug 11, 2023

Researchers discuss the ethical challenges of studying DNA from a 18th–19th century African American community

A population genetics team identified genetic relationship between 23andMe users and enslaved Africans in Catoctin Furnace, Maryland. The researchers consider ethics of sharing results with descendants and other relatives, highlighting importance of proper consent and minimizing harm.

SourceCell Press·JournalAmerican Journal of Human Genetics·TypeCommentary/editorial·DateAug 3, 2023

Social media algorithms exploit how humans learn from their peers

Researchers found that social media algorithms prioritize 'Prestigious, Ingroup, Moral, and Emotional' (PRIME) information, which can lead to extreme political content being amplified. To address this, the study proposes increasing user awareness of algorithmic biases and introducing more diverse content in feeds.

SourceCell Press·JournalTrends in Cognitive Sciences·TypeLiterature review·DateAug 3, 2023

Scientists tie obesity to sex- and age-specific genes

Researchers identified five genes influencing BMI in women and two in men, with faulty variants of three genes linked to higher BMI in women. Age-specific factors also emerged, with genes OBSCN and MADD associated with childhood body size and fat.

SourceCell Press·JournalCell Genomics·TypeObservational study·DateAug 2, 2023

Illegal shooting kills most birds found dead near power lines

A recent study reveals that illegal bird shootings are now the leading cause of death for birds found dead near power lines in the western United States. Researchers analyzed 410 carcasses collected over four years and found that 66% died from being shot, surpassing electrocution as a leading cause.

SourceCell Press·JournaliScience·TypeObservational study·DateAug 1, 2023

Paleontologists identify two new species of sabertooth cat

Researchers discover two new sabertooth species, Dinofelis werdelini and Lokotunjailurus chimsamyae, in a global analysis of Langebaanweg fossils. The study reveals a diverse range of environments in Africa, with Machairodonti cats suggesting open grasslands and Metailurini cats indicating forested areas.

SourceCell Press·JournaliScience·TypeObservational study·DateJul 20, 2023

Understanding the many different ways animals are evolving in response to fire could help conservation efforts

A review of animal evolution in response to fire may help inform conservation strategies, as changing fire regimes impact species. By analyzing nearly 100 papers, the authors identified various adaptations, such as infrared sensory pits and behavioral changes, that enable animals to survive fires.

SourceCell Press·JournalTrends in Ecology & Evolution·TypeLiterature review·DateJul 19, 2023

GPT detectors can be biased against non-native English writers

Researchers found that popular GPT detectors misclassify articles written by non-native English speakers as AI-generated. The study suggests using these detectors with caution and calls for enhancements to address biases. This could have significant implications for students, job applications, and search engines.

SourceCell Press·JournalPatterns·TypeCommentary/editorial·DateJul 10, 2023

Conservation in Indonesia is at risk, a team of researchers who study the region argues

A team of conservation researchers warns that Indonesia's tropical rainforest and endangered species are under threat from government interference and corporate interests. The researchers advocate for data transparency, online 'safe houses', and anonymized journals to protect environmental research and promote nature conservation.

SourceCell Press·JournalCurrent Biology·TypeCommentary/editorial·DateJul 10, 2023

Potential financial losses from a renewable energy transition are concentrated among the wealthy

A recent study published in Joule found that the financial losses from a renewable energy transition are concentrated among the wealthiest individuals. In high-income countries, two-thirds of the losses would affect the top 10% of wealth holders, with half affecting the top 1%. In contrast, lower-income individuals would face minimal l...

SourceCell Press·JournalJoule·TypeObservational study·DateJun 22, 2023

Watch worms use electricity to jump

Researchers discovered that microscopic Caenorhabditis elegans worms can use electric fields to jump across Petri plates or onto insects, allowing them to attach themselves. This behavior is made possible by the natural electric charge of pollinators like bumblebees and hummingbirds.

SourceCell Press·JournalCurrent Biology·TypeExperimental study·DateJun 21, 2023