The journal publishes methodology and statistics to design better trials, reducing publication bias. It features a new method to make cancer clinical trials more effective, with the first issue now available on ScienceDirect.
A new study published in Biological Psychiatry reports the successful reduction of fear in spider-fearful participants following a 2-minute exposure combined with a single dose of propranolol. The treatment resulted in drastically reduced avoidance behavior and increased approach behavior, with effects persisting for one year.
A new study suggests that pomaglumetad methionil, a glutamate pathway target, may be an effective treatment for individuals in the early course of schizophrenia. Researchers found a statistically significant response in patients who are early-in-disease or have not already been exposed to other antipsychotic medications.
A new study published in Biological Psychiatry suggests that cannabis use is associated with increased neural noise in healthy human subjects. The researchers found that delta-9-tetrahydrocannabinol (THC), the primary active constituent of cannabis, induces psychosis-like effects by increasing random brain activity.
Researchers have developed a new method using microwaves to produce BiVO4 nanoparticles for cleaning wastewater, which is 20 times faster and saves energy compared to traditional methods.
The study found that global bicycle ownership has declined from 60% to 32% over the past three decades, with significant variations across regions. The data highlights the need for policy makers to develop targeted strategies to boost cycling as a sustainable mode of transport.
Researchers identify five chemicals that trigger rice plants to fend off white-backed planthoppers, reducing the need for pesticides. The chemicals, phenoxyalkanoic acid derivatives, have shown potential in controlling insect pests and protecting ecosystems.
A study published in the Journal of the American Academy of Child and Adolescent Psychiatry finds that high-quality foster care can reduce the development of callous-unemotional traits in adolescents who experienced parent deprivation. The intervention also showed benefits for boys, particularly those with sensitive caregiver responses.
A new test for club drugs like ketamine can detect low levels of drugs in urine and plasma, making it faster, easier, and cheaper to identify them. The test uses gas chromatography-tandem mass spectrometry and can detect amounts of the drug as low as 5 nanograms per milliliter.
Researchers have identified new, potentially toxic molecules created by cooking with chloraminated tap water and iodized table salt. Limiting cooking time and temperature, using fortified salt instead of iodide, can minimize their formation.
The new guidelines aim to prevent the spread of MDRGNB in healthcare settings, which are already present in the UK. They provide practical advice on identifying patients with these bacteria and preventing their spread.
The European Menopause and Andropause Society (EMAS) has published a position statement on testosterone replacement therapy in the aging male, highlighting the importance of lifestyle modifications before considering TRT. The statement emphasizes the need for careful risk versus benefit estimation and individual evaluation of co-morbid...
A new vaccine has shown promise in reducing 'bad' LDL cholesterol levels in mice and macaques, suggesting potential as an alternative to statins. The vaccine targets the PCSK9 protein, which regulates cholesterol levels in the blood, offering a more powerful treatment with fewer side effects.
A new study published in Food Research International found that eating vanilla yoghurt can make people feel happy due to the pleasant surprise of tasting a different flavor. Researchers discovered that yoghurts with lower fat content also elicit stronger positive emotional responses.
A new study published in Biological Psychiatry found that treatment for insomnia with cognitive behavioral therapy or tai chi reduces inflammation levels in older adults. These behavioral interventions also represent a third pillar, along with diet and physical activity, to promote health and reduce age-related morbidities.
A new study finds that the APOE epsilon 4 allele is associated with an increased risk of late-life depression, even after controlling for Alzheimer's disease. The presence of this allele predicts future depression in older adults, highlighting its potential as a marker for prevention and early detection.
A new study found that early life stress can impair the development of reward circuits in adolescents, increasing the risk of depression. The study revealed a decrease in ventral striatum activity in response to rewards, which predicted the emergence of depressive symptoms.
A new study found that using e-cigarettes is related to problematic drinking, with women more likely to use them socially. The researchers suggest that e-cigarette use could make it harder for people with alcohol addiction to quit drinking.
A new study published in Social Science & Medicine suggests that having skills and freedom at work is linked to lower BMI and smaller waist size, while needing to make many decisions is linked to bigger waist size. The findings highlight the importance of considering job control components separately when assessing their impact on health.
A new study presents a portable smartphone-based detection system using a paper sensor that produces strong signals to detect pesticide thiram. The system integrates nanoparticles, a mini-laser, an optical filter, and software that runs on Android, giving reliable and accurate detection readings at low concentrations.
The 2015 European Resuscitation Council guidelines provide detailed advice on treating cardiac arrest and continue treatment after the heart is restarted. The guidelines emphasize the importance of bystander CPR and recommend specific chest compression rates.
Research published in Heliyon found that women born in summer months were more likely to be healthy adults, with slightly higher birth weights and later onset of puberty. This effect is thought to be linked to increased vitamin D exposure during pregnancy, which can influence childhood growth and development.
A new study in Biological Psychiatry finds that hormonal treatments for sex reassignment alter brain chemistry, increasing serotonin levels in female-to-male transsexuals and decreasing them in male-to-female transsexuals. These changes may explain why testosterone improves symptoms in some forms of depression.
A new study suggests creating quiet marine zones to better understand the impact of human-generated noise on marine animals. The researchers mapped areas of high and low noise pollution in the oceans around Canada and found a correlation between noise levels and animal behavior.
New research shows that candle soot can be used to power the lithium batteries in electric cars, offering a cost-effective and scalable solution. The discovery opens up possibilities for using carbon in more powerful batteries, which could drive down production costs and increase efficiency.
Researchers have developed a polymer blend that significantly improves light output from LEDs by manipulating hole-mobility and exploiting the difference in energy levels of the polymers. The optimized device achieves an ultrahigh efficiency of approximately 27 candelas per amp, outperforming a similar device using only Super Yellow.
Researchers have developed an automated drone-based approach to monitor forest regeneration, reducing costs and labor intensity. The method uses low-cost drones equipped with cameras to create 3D images of vegetation, providing accurate results comparable to human monitoring.
Researchers found that a high-fat diet can cause defective brain signaling in mice, leading to overeating and obesity. Understanding this mechanism may help prevent obesity and reduce its incidence worldwide.
A virulent strain of BVDV-2c virus affected over 5,000 cattle in Germany, causing severe symptoms and significant economic losses. The study suggests that farmers and people who visit farms should take biosecurity measures to prevent disease transmission.
Researchers found that the Alzheimer's drug donepezil increases bone mass in mice by preventing osteoclasts from being made, reducing the risk of bone fractures. The study suggests that treating Alzheimer's disease with donepezil may also be beneficial for patients with osteoporosis.
The new journal Heliyon publishes robust research in various disciplines, including Yard-long beans and cattle studies. The journal aims to improve the author, editor, reviewer, and reader experience using cutting-edge technologies.
A study of 13,583 US adolescents found that exercise for 4+ days a week reduces sadness and suicidal ideation by 23%. Exercise was associated with significant reductions in sadness, suicidal ideation, and attempt across all students, particularly bullied teens.
Synthetic biology holds promise for revolutionizing science and medicine, but its safe and stable application is crucial before being applied in real-world settings. Engineers are working on developing safety infrastructure, including kill switches and microbial sensors, to ensure the reliability and predictability of engineered microbes.
The special issue marks the 10th year anniversary of IPCC SRCCS and outlines significant progress made in CO2 Capture and Storage (CCS) in the last decade. The reviews suggest that CCS is now a mature technology, ready for large-scale deployment to combat climate change.
Three new studies suggest that activating mGluR2 can prevent relapse to cocaine and nicotine use in rodents, as well as reduce methamphetamine cravings. The studies also found that AZD8529, a selective mGluR2 enhancer, showed promising anti-addiction effects in non-human primate models.
Two studies suggest alternative prevention strategies may render surgery unnecessary for women at high risk of breast and ovarian cancer. Researchers identify a new target to decrease breast cancer risk by blocking the effects of RANKL with OPG.
A bioelectronic nose that mimics the human nose can detect traces of bacteria in water by smelling it, without complex equipment. The sensor is sensitive to low levels of contamination, making it more useful than existing methods.
A new Ebola test using magnetic nanoparticles is 100 times more sensitive than current tests and easier to use, enabling faster isolation of patients and prevention of disease spread. This technology has potential applications in diagnosing other infectious diseases like flu and detecting tumors.
A meta-analysis of 1155 patients with schizophrenia and 911 healthy controls found progressive cortical gray matter loss relative to healthy controls, related to cumulative antipsychotic intake. Second-generation antipsychotics showed a neuroprotective effect, reducing progressive loss.
A study published in the Journal of Archaeological Science found evidence of mass breeding of raptors in ancient Egypt, including a mummified kestrel that died from force-feeding. The findings suggest that birds were kept and bred for religious purposes, with implications for falconry practices.
A recent study found that children aged 13-19 who have been abused can regulate their emotions with a little guidance. The researchers tracked the teens' brain activity as they viewed emotional images and were taught cognitive reappraisal, a strategy to alter emotional responses.
A new study reveals that middle-aged drivers use their cellphones regularly while driving, even with children present, and feel pressured to answer work calls. The researchers found that interventions targeting companies can train employees to reduce distracted driving.
Researchers in China have developed tiny nanocrystals that can specifically target and identify cancer cells, potentially leading to earlier diagnosis and treatment. The nanocrystals, made from heavy metals lanthanum and europium, can be used as 'staining' agents to highlight diseased cells under a microscope.
A study of 109 clinicians found that older participants are more likely to believe playing video games leads to violent behavior, highlighting a generational effect. The researchers suggest that parents can help bridge this gap by engaging with their children and trying out the games themselves.
The new online-only journal focuses on interdisciplinary discussion and debate in reproductive biomedicine, including its societal and cultural implications. The first issue covers a symposium of research on the history of the first IVF births.
A recent study assesses e-waste recycling's economic potential and finds it worth billions of euros, with potential revenues expected to rise from €2 billion in 2014 to €3.5 billion by 2020. The recycling industry also aims to reduce environmental pollution by conserving virgin resources.
The Society of Obstetricians and Gynaecologists of Canada has selected Elsevier to publish its journal JOGC, a leading peer-reviewed publication on obstetrics and gynaecology. The partnership aims to improve the journal's content and services for its members and the wider medical community.
Researchers developed a stem cell model to assess the neurotoxicity of Bisphenol A (BPA) efficiently and cost-effectively. The study showed that BPA may alter embryonic development in vivo, highlighting the potential health risks associated with environmental pollution.
A recent study published in The Annals of Thoracic Surgery found that patients with suspected lung cancer often wait too long to receive treatment and skip vital diagnostic steps. Only 1 in 10 patients had the recommended combination of three staging tests before surgery, highlighting the need for improved quality care.
The new guidelines offer evidence-based recommendations for optimal temperature management during cardiopulmonary bypass, including cooling and rewarming rates. The guidelines aim to improve understanding of the relationship between temperature management and clinical outcomes, particularly its impact on brain function.