Researchers have identified a new class of molecules called selenocompounds that can kill multidrug-resistant cancer cells by blocking their defenses against chemotherapy drugs. The most active molecule worked almost four times better than the reference compound and induced cell suicide in cancer cells with similar potency.
A new study found that subjecting female soccer players to negative stereotypes about their abilities reduced their dribbling speed significantly. The researchers discovered no significant relationship between reading negative stereotypes and flow or worry, but found that girls who felt more worried spent less time on the task.
A new method for extracting, enriching and identifying chemical warfare agents from oils and organic liquids has been developed, using nanoparticles to capture the chemicals. The method can identify agents at low concentrations, overcomes challenges of detecting water-repellent agents, and has potential to save lives.
A new study by CDC finds that individuals with epilepsy have a 22% higher suicide rate compared to the general population. The study analyzed data from the US National Violent Death Reporting System and found that 17 out of 100,000 people with epilepsy died from suicide each year.
The European Menopause and Andropause Society publishes a new position statement on healthy menopause and aging. The model emphasizes a holistic approach to midlife women's physical, psychological, and social well-being. It recommends specialist teams and interdisciplinary networks for optimal care.
A new study in Biological Psychiatry reveals that inflammation of the hippocampus contributes to depressive symptoms in multiple sclerosis patients. Hippocampal immune activation was linked to more severe symptoms of depression and altered functional connections with other brain regions.
A new meta-analysis in Biological Psychiatry reports associations between sleep disturbances and long sleep duration with increased levels of inflammatory markers. Treatments targeting sleep behavior may be a strategy for reversing inflammation and reducing risk of inflammatory illnesses.
A new study found that adolescents living in neighborhoods with more greenery have less aggressive behaviors. The researchers linked the adolescents' residential locations to satellite data, measuring the levels of greenery and associated it with reduced aggressive behaviors.
A study in the Journal of Transport & Health found that car ownership reduces exercise during travel, while bike ownership promotes it. Londoners who mainly walk or cycle for their trips tend to be more active.
Researchers found a unique 'texting rhythm' in approximately 1 in 5 patients using smartphones while having their brain waves monitored. The study suggests that texting can change brain waves and may have significant implications for brain-computer interfacing, gaming, and driving.
A new study published in Biological Psychiatry suggests that prenatal cannabis exposure is associated with thicker prefrontal cortex in children. The study found no differences in overall brain volume, but highlights the importance of preventing cannabis and cigarette use during pregnancy.
Researchers found that tiny lipid bubbles packed with melatonin can make tamoxifen stronger and help kill cancer cells. The treatment reduces the need for higher doses of tamoxifen, minimizing severe side effects.
Researchers have discovered a new class of antimicrobial materials that use carbon nanodots to kill drug-resistant bacteria. The materials, which include molecules such as PAMAM, exhibit greater efficacy against certain strains of E. coli and Klebsiella pneumoniae, and may also enhance the effectiveness of existing antibiotics.
A new breath test has been developed to identify lung cancer after surgery, using a simple, affordable process that analyzes carbonyl volatile organic compounds in exhaled breath. The test shows great potential for detecting lung cancer at any point, both as primary screening and post-surgery monitoring.
A new study published in Biological Psychiatry suggests that glial energy metabolism plays a critical role in addiction-related behaviors. Researchers found that altering glial lactate release and nerve cell uptake of lactate prevented long-lasting relapse in rodents.
The Nordic countries exhibit both high levels of gender equality and disproportionately high rates of intimate partner violence (IPV) against women. Despite these contradictions, researchers believe that understanding the underlying causes may offer tools to combat IPV globally.
A series of studies published in Water Research assesses the ecological and chemical responses to geo-engineering in lakes. While some case studies report dramatic improvements, others show little effect or short-lived responses. The approach is promising when used correctly, but its potential side effects are not well understood.
Researchers report that two topical creams are effective in most primary, low-risk superficial BCC patients, with favorable comparison to photodynamic therapy. The study found high clearance rates for imiquimod and fluorouracil treatments, but noted a higher recurrence rate for fluorouracil.
A meta-analysis of 39 studies found that one in ten youths treated with an antipsychotic have autism spectrum disorder or intellectual disability. The study suggests that more youths with autism or intellectual disability have received antipsychotics, raising concerns over their efficacy and potential side effects.
Researchers monitored social media in real-time to identify Zika conspiracy theories that could be affecting people's health-related decisions. The study found nearly 140,000 Tweets with keywords 'vaccine' and 'Zika,' highlighting the need for public health authorities to address concerns and debunk unscientific claims.
Researchers discovered six VOCs responsible for bad smells on dirty clothes, which are significantly reduced after washing. The study provides new insights into the impact of washing temperatures and detergents on fabric smell, potentially leading to more environmentally friendly cleaning methods.
Researchers have identified a 'weekend effect' contributing to the decline in donor kidney availability in the US. Organs procured on Fridays and Saturdays were more likely to be discarded than those during weekdays, with higher quality kidneys also being thrown away at a greater rate.
A new care pathway provides evidence-based information for healthcare professionals to address menopausal symptoms, osteoporosis, and cardiovascular disease. The pathway emphasizes holistic assessment and personalized approach to maintaining post-reproductive health.
Researchers found that 5-year survival for older lung cancer patients is favorable, with median survival at 6.7 years, and long-term patient outcomes including reduced hospital readmission rates and reinterventions.
A new study found that vasopressin increases placebo analgesic effects in women, particularly those with lower acute stress and anxiety. The findings suggest a new mechanism for the neurobiology of placebo effects and open up research directions for understanding the vasopressin system.
Research found that children exposed to selective serotonin reuptake inhibitors (SSRIs) during gestation had a cumulative incidence of 8.2% of depression by age 15, compared to 1.9% for those without antidepressant use. The study also showed no significant difference in anxiety or ASD diagnoses.
Researchers modified an obesity drug to block brain penetration, reducing psychiatric side effects. The new version of the drug can work on cannabinoid receptors outside the brain.
Researchers found structural brain damage in the hippocampus, a key memory region, that correlates with memory performance and disease severity in patients with anti-NMDA receptor encephalitis. The autoimmune disorder can cause schizophrenia-like symptoms and long-term cognitive impairment if not treated promptly.
A new catheter infection alert system could prevent serious infections in millions of hospital patients and elderly people. The system changes the color of urine to detect bacterial blockages before they cause kidney failure and death.
Researchers developed a compound called KUSs that may help prevent nerve damage in glaucoma, allowing patients to maintain near-normal vision. Early tests in mice showed promising results, suggesting these compounds could slow down disease progression and potentially treat other neurodegenerative diseases.
The Green and Sustainable Chemistry Challenge has selected two winning projects that offer environmentally friendly processes, products, and resources for use in developing countries. Yunsang Kim's project uses nanocellulosic fibers to reduce wastewater and toxic chemicals in textile dyeing, while Suzana Yusup's project develops a wate...
The International Journal of Gynecology and Obstetrics identifies key factors associated with intimate partner violence, including infertility/subfertility as a risk factor in low- and middle-income countries. The research contributes to efforts to establish ways to identify individuals at risk and develop successful interventions.
A study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that remote eye gaze tracking can differentiate children with autism spectrum disorder from those without ASD. The researchers developed an Autism Risk Index based on eye gaze patterns, which correctly identified 4 out of 5 cases of ASD.
The study analyzed 105,002 elderly patients' outcomes from 2000 to 2014, showing improved overall mortality rates and reduced length of hospital stay. However, factors such as age, pre-existing disease, and weekend operations increased in-hospital mortality
Researchers have developed smaller, cheaper microbial fuel cells that can efficiently produce bioenergy from urine. The new design increases power output and reduces costs compared to traditional models.
A recent study suggests that decreased dietary diversity leads to reduced gut microbiota richness, which is associated with various metabolic disorders. The researchers emphasize the importance of dietary diversity for maintaining a healthy gastrointestinal microbiome.
A new study reveals that European honeybees are being poisoned with up to 57 different pesticides, posing a threat to bee populations worldwide. The researchers developed a method for analyzing 200 pesticides simultaneously, providing critical information on the toxic mix and its impact on honeybee health.
A new review proposes using cheap and quick point-of-care tests to measure beta-amyloid levels in the blood, enabling doctors to deliver personalized care and improving patients' quality of life. The tests could be especially beneficial for patients in developing countries where access to healthcare is limited.
A new study found that a computer-based attention bias modification treatment reduced negative attention biases and clinician-rated depressive symptoms in adolescents with major depression. After 12 months, participants in the active ABM group reported even greater reductions in self-reported depressive and anxious feelings.
A new study suggests that multinational companies have a growing responsibility to support sustainable development, driven by changing societal expectations. The research, published in the Journal of World Business, tracks changes in corporate social responsibility (CSR) over 50 years.
A new study found that no disinfectant completely removes bacterial biofilms from dental water lines, posing a significant infection risk. Researchers recommend preventing the formation of biofilms as key to keeping lines clean, and suggest using good quality water, prevention disinfectants, and avoiding stagnation.
Elsevier has launched Transplantation Reports, an online-only, open-access journal serving the international transplant community. The journal will publish original research, reviews, editorials, and commentaries related to transplantation.
Rescue teams can improve their chances of finding survivors by understanding the scent profile of decomposition. Researchers identified 105 volatile organic compounds in pig carcasses, changing drastically at the 43-hour mark.
A computer model suggests that cutting incarceration can decrease the number of sexual partners men and women have, thus reducing the spread of sexually transmitted infections. The study also found that harsher penalties may exacerbate this effect, highlighting the need for more open criminal justice systems.
A large-scale study found a significant link between traffic-related air pollution and the formation of lentigenes (facial dark spots) on cheeks of Asian women over 50. The study also showed that exposure to nitrogen dioxide gas had a stronger impact on dark spot formation than particulate matter.
Researchers discovered a large amount of fish bones fermented in a pit around 9,200 years ago, suggesting the ancient Scandinavians had more advanced technology and culture. This finding compares to Neolithic people in the Middle East, who were traditionally thought to have settled earlier.
Researchers report successful reduction of depressive symptoms in patients using a novel non-invasive method of vagus nerve stimulation. The transcutaneous approach, which stimulates the vagus nerve through electrodes clipped onto the ear, shows promise as a low-cost and safe treatment option.
A new study published in Biological Psychiatry suggests that inflammation can directly affect the brain's reward center, leading to changes in behavior similar to depression. The study found that patients with hepatitis C who received interferon-alpha treatment showed microstructural changes in their striatum, which was associated with...
A new study found that 75% of vaccine-related posts on Pinterest are negative towards vaccination, highlighting the need for better communication about vaccination. The researchers argue that institutions need to value public engagement and advocacy to effectively promote vaccines.
A recent study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that adolescents who were chronically victimized during school years are five times more likely to think about suicide and six times more likely to attempt it at 15. The research highlights the importance of early interventions to p...