New research shows tirzepatide consistently reduces bodyweight and waist circumference, with greater reductions in participants with longer disease durations. Tirzepatide also achieves higher weight loss targets and reduces waist circumference more significantly than placebo across all disease duration categories.
New Norwegian research reveals a strong association between parental BMI and offspring's obesity status, even after adulthood. Individuals with both parents living with obesity have six times higher odds of developing obesity in middle age.
Researchers analyzed cortisol and cortisone levels in over 6,300 individuals to find a strong link between long-term hair cortisone levels and future cardiovascular disease. People with higher cortisone levels were twice as likely to experience a cardiovascular event, especially those aged 57 or younger.
A new study found that the gut microbiota of toddlers at 3.5 years old is predictive of body mass index (BMI) at age 5, with certain types of bacteria associated with a higher or lower risk of obesity. The research also suggests that changes in the gut microbiota begin in early childhood and can influence weight gain later in life.
A multicentre, one-year real-world study found semaglutide effective for weight loss in patients with overweight and obesity, with 82% losing over 5% body weight. The medication also improved metabolic parameters, including blood pressure and cholesterol levels.
A study found that semaglutide use for one year decreases the 10-year atherosclerotic cardiovascular disease (ASCVD) risk score in patients with overweight or obesity. The treatment also leads to significant improvements in metabolic parameters, such as blood pressure, cholesterol, and fasting glucose levels.
Teenagers living with obesity who experience uncontrolled hunger are more likely to perceive their weight as negative, worried about its health effects, and actively trying to lose weight. They also report greater dissatisfaction with their body image and higher rates of bullying.
A Dutch study found that individuals who feel safe in their neighborhoods lose more weight during lifestyle interventions. Those with higher scores on a safety scale experienced greater decreases in weight and waist circumference, regardless of sex, age, or education level.
A new analysis of the SURMOUNT-1 study shows that tirzepatide improves body composition across a range of adult age groups, with significant reductions in fat mass. The treatment also results in a clinically meaningful improvement in body composition, with only one-quarter of weight lost being lean mass.
Research suggests that simple initiatives to promote lower-calorie options on delivery apps can significantly reduce the average excess calorie content of orders. The interventions tested included pre-selecting smaller portions, positioning lower-calorie foods and restaurants more prominently, and displaying calorie labels.
Research suggests whole body cryostimulation improves cholesterol and blood sugar levels in individuals with obesity. After two weeks, the WBC group experienced a greater reduction in waist circumference and blood glucose levels compared to the sham treatment.
A new substudy of the STEP TEENS trial shows that semaglutide significantly reduces levels of liver enzymes, including alanine aminotransferase (ALT), which are indicators of liver damage. The study found improvements in ALT levels with weight loss of ≥10%.
Research finds past obesity associated with greater depressive symptoms and impaired psychological wellbeing, even after weight loss. Past obesity may be 'psychologically scarring', increasing the risk of early death by around 30%.
A new study suggests that cold exposure in the morning may be more effective at boosting metabolism and burning fat than in the evening, especially in men. In women, however, there was no significant difference in response to cold exposure times, but they were more tolerant of cold in the morning.
A study of treatment-naïve transgender youth found that nearly two-thirds reported eating an unhealthy diet, over three-quarters did not engage in physical activity, and half did not get enough sleep. The research highlights the need for individualized medical and nutrition interventions to protect their long-term metabolic and cardiov...
Researchers have identified a new mechanism of communication between fat cells, opening up avenues for novel obesity treatments. The discovery centers on tunnelling nanotubes, which allow distant cells to communicate directly and transfer cargos.
A new study found that ear acupuncture with beads can help reduce waist circumference, body fat, and BMI in men living with obesity. Participants who received auricular acupuncture with beads lost an average of 10.4cm off their waist circumference and 4% of total body fat.
A UK study of over 420,000 adults reveals that those with existing cardiovascular disease and overweight or obesity are five times more likely to suffer a stroke and four times more likely to have a heart attack than those with extreme obesity. The study highlights the substantial impact of living with both conditions on individuals, p...
A new treatment combining a swallowable gastric balloon with the anti-obesity drug liraglutide is safe and effective for boosting weight loss. Participants lost an average of 19% of their initial body weight and reduced BMI by 4.5kg/m2 after 8 months of treatment.
Research suggests weight gain between ages 17-29 increases aggressive prostate cancer risk by 13% and fatal prostate cancer risk by 27%. Preventing weight gain in young adulthood may reduce prostate cancer risk. The study analyzed data from over 250,000 Swedish men, finding a significant association between weight gain and prostate can...
Research reveals both metabolically healthy and unhealthy obesity types linked to increased risk of various obesity-related cancers, with stronger association in metabolically unhealthy obesity. Metabolically unhealthy women face higher risks for endometrial, liver, and kidney cancers.
A recent study found that a vast majority of tweets about obesity are negative, with only 8.25% containing positive sentiments. The analysis suggests that Twitter activity spiked around significant political events, including comments from influential politicians and celebrities.
A UK study of nearly 400,000 adults found that being overweight or obese amplifies the harmful effects of alcohol on cancer risk. Higher obesity levels are associated with a greater risk of developing both obesity-related and alcohol-related cancers, regardless of alcohol consumption.
A study suggests that women who have had weight loss surgery should wait at least two years before trying for a baby due to the risk of having an underweight (small for gestational age) baby. The longer interval from surgery to conception is associated with a lower risk of SGA babies.
A recent study by Nationwide Children's Hospital found that low-income US children and teenagers experienced significant weight gain during the first 3–6 months of the COVID-19 pandemic. This trend was particularly pronounced among younger children, girls, and ethnic-minority youth.
A recent study found that only 3% of adults with a recording of overweight or obesity in England are referred to weight management programmes, indicating under-reporting in primary care. The programme's effectiveness varies across the country, and the lack of national registry makes it difficult to determine access for patients.
Women with obesity and high waist circumference are more susceptible to fractures than those with normal weight. The study found a linear relationship between waist circumference and the incidence of fracture at any site and at the distal lower limb, particularly at the ankle.
Obesity rates in Denmark have increased dramatically, from 6% in 1987 to over 18% in 2021, with a strong period effect observed. The study highlights the need for concerted action to reverse this trend and addresses social inequality in obesity.
A UK study of over a million adults found that young adults (under 45) and women were more likely to gain weight and move up at least one BMI category during lockdown. The study suggests that this could lead to an increased risk of obesity-related health problems, including diabetes, heart disease, and cancer.
A new study at the European Congress on Obesity found that toddlers who were rewarded for trying vegetables ate more of them. The study, which involved 598 children aged 1-4, showed that regularly offering vegetables increased recognition and willingness to try different types.
A meta-analysis of 11 randomised trials found that vegan diets for at least 12 weeks can lead to clinically meaningful weight loss and improved blood sugar control. However, vegan diets did not affect blood pressure or triglycerides compared to other diets.
Researchers found antibody levels in people with severe obesity are significantly lower than normal weight controls after receiving two doses of either the Pfizer/BioNTech or CoronaVac vaccine. The study suggests that individuals with severe obesity may generate a weaker immune response to COVID-19 vaccination.
Researchers analyzed 364 social media posts by six German-speaking influencers and found that 75% of the featured food and drinks were high in salt, fat, or sugar, exceeding World Health Organization advertising standards for children. Chocolate and sweets were the most commonly posted about products.
A randomised trial found that poor sleeping habits may contribute to regaining weight after weight loss in adults with obesity. Exercise sessions per week can help maintain better sleep and aid in weight loss maintenance.
A 10-country survey of adolescents with obesity found that nearly 24% are unaware they have the condition, while two-thirds believe it's their sole responsibility to lose weight. Most participants worry about the impact of obesity on their future health.
A recent study published in BMC Medicine found that obesity is associated with an increased risk of fatal prostate cancer. For every 10cm (four inches) on the waist, the risk of fatal disease increases by 7%. The study analyzed data from over 2.5 million men and found a link between body fat and prostate cancer risk.
A review of over a decade of data from the HOLBAEK Study reveals wide range of obesity-related complications present at young age, including dyslipidaemia and sleep apnoea. The study also found family-based weight management programmes to have positive effects on overweight and related complications.
A new study suggests that a diet high in protein, zinc, and niacin, and low in saturated fat, can improve blood vessel flexibility. The study found improvements in metabolic and cardiovascular health, including reductions in calorie and saturated fat intake, increases in zinc and niacin, and improvements in blood vessel function.
A Danish study of over 1,000 children found that changes in blood fats and markers of heart health and diabetes can be detected as early as age six in those with overweight. Routine dental check-ups provide a good opportunity to measure BMI.
A UK study found that 70% of adolescents are not consuming the recommended amount of fruit and over 90% are not eating enough vegetables. The researchers analyzed data from 16 schools in the West Midlands region, finding that pupils were exceeding daily intake limits for free sugar, potatoes, red meat, and chicken.
A UK study of over 400,000 adults with obesity found that losing weight reduces the risk of 13 obesity-related complications, with greater benefits for those with lower initial BMIs. Weight gain increases these risks, particularly in individuals with lower starting BMIs.
A European survey found that over three-quarters of adults with obesity have attempted to lose weight in the past year. Most respondents used diet or exercise strategies, but only 25% achieved clinically meaningful weight loss. The study highlights the need for increased support and solutions for weight management.
The European Region has the highest obesity prevalence among all WHO regions, with 59% of adults and 29% of children classified as overweight or obese. To address this growing epidemic, the WHO recommends a range of interventions and policy options to prevent and tackle obesity, including building back better after the COVID-19 pandemic.
A new study analyzed the UK's largest contemporary dietary dataset of toddlers, finding that only 16% met the recommended intake of free sugars. The majority of free sugars consumed by children come from pure fruit juices, yogurts, and processed foods.
Research shows that around three quarters of total US healthcare costs for people with obesity are accounted for by the 20% highest-cost cases. These high-cost individuals had substantially more obesity-related complications and economic burden than those in lower cost categories.
The European Association for the Study of Obesity provides evidence-based physical activity recommendations for adults with overweight and obesity. The guidelines highlight the benefits of exercise training on health and wellbeing beyond weight loss.
A study found that obese people with an evening chronotype, characterized by later waking and peak activity, have a significantly higher risk of developing type 2 diabetes and cardiovascular disease. This increased risk is independent of sleep quality, age, gender, and body mass index.
A phase 1 study found that combining cagrilintide, a long-acting amylin analogue, with semaglutide led to greater weight loss compared to semaglutide alone. The combination was well-tolerated and showed an acceptable safety profile.
A new study has found a reduced risk of eye cataracts associated with obesity surgery. Patients who underwent weight loss through bariatric surgery showed a lower incidence of cataract compared to those who did not have surgery, especially when performed before age 60.
Researchers found that semaglutide treatment leads to significant weight loss across various patient groups, including those with different ages, sexes, and body weights. Female participants and those with lower starting body weights achieved the most substantial weight losses.