The FASEB MARC Program conferred 11 travel awards totaling $20,350 to promote underrepresented minority students and scientists in immunohistochemistry and microscopy. The awards aim to increase diversity in biomedical research and encourage young scientists' participation.
The Human Microbiome Project is a major scientific effort to study the microbial communities within humans, with potential insights into diseases and disorders. The study, published in The FASEB Journal, provides a comprehensive reference set of microbiome specimens and lays a foundation for future research.
Research published in The FASEB Journal suggests that pregnant mothers who consume junk food alter the development of their unborn child's opioid signaling pathway, leading to decreased sensitivity and increased tolerance for junk food. This can result in children being more likely to develop a lifelong addiction to unhealthy foods.
Research published in Journal of Leukocyte Biology reveals that progesterone receptor regulates helper T cells required for developing antibodies. This regulation affects immunity against diseases like malaria and herpes simplex virus, and sheds light on autoimmune disease remission during pregnancy.
Researchers found that the Achilles tendon remains unchanged despite repeated high-impact loading. Human tissue samples from individuals exposed to nuclear bomb tests showed persistent radiocarbon levels decades after the event.
Researchers have identified a new mechanism by which the bladder senses its level of fullness through integrin proteins. This discovery may lead to the development of new drugs targeting this pathway to treat overactive bladder and incontinence.
Researchers found that oleuropein aglycone, a compound in olive oil, significantly reduces inflammation and tissue damage caused by intestinal ischemia and reperfusion injury. The study suggests potential therapeutic benefits for patients with spinal cord injuries, arthritis, and pleurisy.
The conference focuses on rapidly growing fields of interest in gastrointestinal disciplines, including epithelial biology and gut microbial ecology. Scientists will explore translation of basic findings to diseases like inflammatory bowel disease and intestinal cancer.
Scientists produced a monoclonal antibody in transgenic tobacco plants that neutralizes the rabies virus by preventing it from attaching to nerve endings. This new antibody opens the prospect of adequate rabies prevention for low-income families in developing countries.
A network of steroid molecules found in the brain is disrupted during HIV infection, leading to brain damage. Treatment with DHEA-S has been shown to prevent neuronal damage and reduce neurovirulence.
The bacteria Porphyromonas gingivalis causes excess IL-10 production, inhibiting T-cell function and leading to infection. Early intervention is crucial to prevent chronic periodontal disease.
A new research report published in the FASEB Journal shows that TFP5, a small molecule, rescues plaques and tangles by blocking an overactive brain signal, restoring memory in mice with Alzheimer's. Clinical trial studies may yield extended quality of life for patients.
Researchers found a compound called ebselen effectively inhibits the thioredoxin reductase system in Helicobacter pylori, which causes gastric ulcers, and Mycobacterium tuberculosis, which causes tuberculosis. Ebselen's mechanism targets bacteria lacking glutathione.
The FASEB MARC Program has awarded $3,700 to two students and their faculty mentors at the ISCB Rocky 2012 meeting. The program aims to increase diversity in biomedical research by promoting participation of underrepresented minority students and scientists.
Researchers discover that JQ1 can reactivate latent HIV by activating the virus in the presence of potent therapy, making it vulnerable to current treatments. The study also found potent suppression of inflammatory genes, suggesting its potential effectiveness against other inflammatory conditions.
A new study suggests that daily exposure to low-magnitude mechanical signals partially rescues B- and T-cell populations damaged by obesity, improving immune function. Brief daily vibration interventions showed promise in obese mice, potentially leading to a cheap and drug-free way for people to regain health.
A new genetic test can accurately identify the presence of breast cancer tumors and predict the progression of tumor development. This breakthrough technology analyzes genetic switches to detect cancer growth, enabling earlier diagnosis and more effective treatment plans.
Scientists have discovered several toxins in sea anemones that could be used as new generation of insecticides. These toxins disable ion channels, potentially leading to the development of pain and cardiac disorder treatments.
Researchers identify SRGAP3 protein as root cause of several childhood psychiatric disorders, including schizophrenia, autism, and hydrocephalus. The discovery opens new avenues for targeted treatments rather than symptom relief.
A recent study published in the Journal of Leukocyte Biology found that T-cells responsible for controlling herpes viruses are reduced significantly during new infections, allowing latent viruses to reactivate. This understanding could lead to prevention strategies and improved treatment options for people with herpes.
A new study published in the FASEB Journal found that bimatoprost, a commonly prescribed glaucoma drug, stimulates human hair growth from the scalp. The drug has been commercially available to lengthen eyelashes, but this is its first application for treating baldness.
Researchers found that spaceflight compromises the ability of arteries and veins to constrict, leading to orthostatic hypotension upon return to Earth. This condition affects up to half of astronauts on short-term missions and nearly all on long-term missions.
The editorial discusses the evolution of doping scandals from ancient times to modern-day sports, highlighting the need for continuous innovation in detection methods. Bowers emphasizes the importance of analytical skills, pharmacokinetics, and human physiology in preventing abuse in sport.
A new study published in The FASEB Journal suggests that being born with a low birth weight may increase the risk of developing cardiovascular disease, kidney disease, and diabetes later in life. Researchers found that older female rats had a reduced ability to become pregnant and carried babies that were smaller or lighter in weight.
Research reveals that activated macrophages accumulate triglycerides to support their function, leading to increased pathogen destruction. This finding provides new insights into the development of atherosclerosis and potential approaches to slowing its progression.
Researchers found a new class of antibody in camelids that can cross the blood-brain barrier, diffusing into brain tissue to reach specific targets. This breakthrough may lead to enhanced imaging and improved drug delivery for people with brain diseases like Alzheimer's.
Researchers found that a mother's diet before pregnancy can induce epigenetic changes in her genes, which are then inherited by her offspring. These changes affect the metabolism of essential fatty acids in the pups' livers. The study suggests a potential link between maternal nutrition and children's health outcomes.
Researchers discovered that a protein called SIRT1 rewrites the histone code in developing fetuses, affecting their likelihood of being overweight or obese. Modifying fat intake during pregnancy to a moderate level can benefit children, regardless of mother's size.
myIDP is an interactive online tool that helps scientists prepare individual development plans to reach their career goals. The platform provides exercises, resource lists, and guidance on exploring career options and setting professional development goals.
Research suggests cancer produces negative immune response in dendritic cells, hindering desired responses. Flawed dendritic cells could aid in preventing autoimmune disorders, however.
Researchers have discovered that Grb10 protein plays a crucial role in increasing muscle mass during development, which could lead to new strategies for treating muscle wasting conditions and metabolic disorders. The study found that blocking Grb10 function while mice were in the womb resulted in increased muscle strength and mass.
Research in the FASEB Journal suggests that sneezing is a biological response to the nose's 'blue screen of death', and patients with sinusitis may sneeze more frequently due to inefficient clearance of mucus. This understanding could aid in the development of new treatments for chronic sinusitis.
Researchers found that IL-10 production by keratinocytes in donor skin is crucial for successful skin grafting between genetically identical mice. Monitoring IL-10 levels may improve therapeutic success in human patients.
Researchers discovered that blocking delta opioid receptors in mice reduced body weight despite high-fat and sugar diets. The study found increased non-shivering thermogenesis due to gene expression changes in brown adipose tissue.
A new study published in the FASEB Journal reveals that a molecule called 'flightless' significantly helps control cell movement through tissues. By increasing the stickiness of cells to underlying tissue, flightless slows their movement and may prevent cancer from spreading from one tissue to another.
A new study suggests that choline supplementation during pregnancy can alter epigenetic expression of genes involved in cortisol production, leading to lower cortisol levels in babies. This can potentially reduce the risk of stress-related diseases throughout a child's life.
Research published in the FASEB Journal reveals a link between maternal stress and abdominal obesity in mice offspring. The study found that manipulating the neuropeptide Y system in visceral fat may prevent stress-induced obesity, offering potential insight into how to counteract the negative effects of stress.
The FASEB MARC Program has awarded $14,800 to 8 recipients at the 2012 SSR Annual Meeting to promote diversity in biomedical research. The program aims to increase the number of underrepresented minorities engaged in biomedical research.
The International Society for Advancement of Cytometry presented its 2012 awards to Dr. Leon Terstappen and Dr. Robert Leif, recognizing their innovative work in cytometry technology. The awards also honored Drs. Jan Visser and Peter Lansdorp for their significant contributions to the field and society.
Research published in the FASEB Journal found that pregnant mice exposed to diesel exhaust were more likely to have obese offspring with insulin resistance. The study suggests a link between air pollution exposure in utero and metabolic disorders in adulthood. Males were particularly affected, while females only showed increased weight...
Researchers have identified a new strategy to thin thick mucus in cystic fibrosis and COPD using the SPLUNC1 protein and its synthetic derivatives. This may lead to improved mucus clearance and better lung function for those affected.
Researchers identify microRNA-320a as a key regulator of glycolysis in tumors and unused muscles, potentially leading to new treatments for lung cancer and improving ventilator recovery. This discovery offers a significant therapeutic leap for numerous diseases and health conditions.
A new research in the FASEB Journal suggests that the AMPK protein helps protect sensory cells in the inner ear from permanent damage and maintains hearing after extreme noise exposure. The discovery provides a target for new preventive strategies and potentially even treatments for earbud deafness syndrome.
Researchers found that people with osteoarthritis have a signature epigenetic change responsible for increasing the levels of the destructive MMP13 enzyme. This discovery provides hope for targeted drug development to prevent disease progression and improve quality of life for arthritis sufferers.
Researchers found that blocking adenosine receptors can reduce scar size and improve skin quality, offering new hope for victims of burns, wounds, or illnesses. The discovery could lead to new agents diminishing scarring and disfigurement.
A new study found that the number of viruses involved in a flu infection impacts the immune response, with high-dose infections generating stronger immunity and increased protection against reinfection. This discovery could lead to improved vaccine design and broader protection against emerging flu strains.
A new fossil discovery solves the mystery of flatfish evolution, revealing a 50-million-year-old fossil fish named Heteronectes that shows an intermediate stage between most fish and specialized flatfish. The study provides evidence for the gradual evolution of flatfish anatomy.
A new study published in the FASEB Journal reveals that smoking before conception can damage genetic information in sperm cells, potentially harming offspring with increased risk of cancer and other diseases. The research highlights the importance of quitting smoking for men trying to conceive.
Researchers found that elevated erythropoietin in the brain improved motivation for higher exercise performance in mice. The study suggests a potential new approach to increasing physical activity, which could benefit people with mental health disorders and other health problems.
Researchers use green fluorescent protein to detect defective genes in children with glycosylation disorders, enabling the development of targeted therapies. The tool helps identify genes causing intellectual disability, digestive problems, seizures, and low blood sugar in children.