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Harvard University


HSCI researchers extend human epigenomic map

HSCI researchers mapped nearly all cytosine-guanine pairs in human DNA and found that only a small fraction are dynamic, playing a key role in regulating gene expression. The study improves current approaches to mapping epigenetic marks and sheds light on how genes are controlled in different cell types.

SourceHarvard University·JournalNature·DateAug 8, 2013

Seeing depth through a single lens

Researchers at Harvard University develop a method for creating 3D images from two stationary frames, enabling amateur photographers and microscopists to capture stereo-like effects. This technique uses light-field moment imaging to infer the angle of light at each pixel, allowing for the creation of brand-new images as if the camera h...

SourceHarvard University·JournalOptics Letters·DateAug 5, 2013

Binding together repelling atoms

Theoretical predictions show that controlled noise from an environment can bind repelling atoms together, creating a bound state with exotic properties. This novel mechanism could lead to improved cooling of atomic quantum gases.

SourceHarvard University·JournalNature Communications·DateJul 31, 2013

Bacterial blockade

Harvard scientists have identified a pair of genes that allow certain gut bacteria to break down a widely prescribed cardiac drug into an inactive compound. The researchers found that these genes are expressed when the bacteria are exposed to the drug, and that they play a key role in converting the drug into its inactive form.

SourceHarvard University·JournalScience·DateJul 25, 2013

Perfecting digital imaging

Researchers at Harvard University are developing new techniques to improve digital imaging, including a method to mimic the appearance of translucent objects and optimize screen hardware for adaptive displays. Their work has the potential to advance artificial vision, 3D displays, and video editing.

SourceHarvard University·JournalACM Transactions on Graphics·DateJul 23, 2013

The genetic key to conquering cholera

A team of Harvard scientists has identified genetic areas in the genome that may help protect against cholera by regulating immune system functions and fluid loss. The study's findings suggest a new approach to understanding host immunity and developing vaccines and therapies for this deadly disease.

SourceHarvard University·JournalScience Translational Medicine·DateJul 19, 2013

Efficiency in the forest

A Harvard study found that forests across the globe are becoming more efficient in using water, contrary to expectations. The research team used long-term data from over 20 years of eddy covariance measurements to show that forests are storing more carbon and growing faster due to increased atmospheric carbon dioxide levels.

SourceHarvard University·JournalNature·DateJul 10, 2013

The evolution of throwing

Researchers found a suite of changes in human shoulders and arms allowed efficient hunting by throwing projectiles, paving the way for later adaptations like increased brain size and migration out of Africa. The study suggests that humans' ability to throw played a key role in becoming part-time carnivores.

SourceHarvard University·JournalNature·DateJun 26, 2013

A new target for cancer drug development

Harvard researchers have identified the SALL4 gene as a key player in tumor formation, and have demonstrated that blocking its activity can halt cancer growth. The study provides new hope for treating aggressive forms of leukemia and other cancers.

SourceHarvard University·JournalNew England Journal of Medicine·DateJun 17, 2013

Reputation can trump money

A study by Harvard researchers shows that making participation observable can significantly increase sign-ups for a California blackout prevention program, with a three-fold increase compared to using cash incentives alone. Observability puts people's reputation at stake, encouraging those who might not otherwise sign up to do so.

SourceHarvard University·JournalProceedings of the National Academy of Sciences·DateJun 10, 2013

Detecting mirror molecules

Harvard physicists develop a novel technique to detect molecular variants in chemical mixtures, relying on microwave fields to identify left- and right-handed compounds. The method can analyze complex mixtures and determine the ratio of variants, with potential applications in pharmaceutical development.

SourceHarvard University·JournalNature·DateMay 22, 2013

Beautiful 'flowers' self-assemble in a beaker

At Harvard University, scientists have developed a method to assemble intricate nanostructures into delicate flower-like structures. By manipulating chemical gradients, researchers can control the growth behavior of these crystals to create precisely tailored structures, mimicking nature's own self-assembly processes.

SourceHarvard University·JournalScience·DateMay 16, 2013

Turning old hearts

Harvard Stem Cell Institute researchers have identified a protein, GDF-11, that reverses the effects of aging on mouse hearts. The protein was found to reduce heart size and thickness, similar to healthy younger mice.

SourceHarvard University·JournalCell·DateMay 9, 2013

Saving money on medical costs

A slowdown in healthcare spending growth could result in Americans saving up to $770 billion on Medicare costs over the next decade. This decrease is attributed to a decline in new drug development and increased efficiency in the healthcare system.

SourceHarvard University·JournalHealth Affairs·DateMay 6, 2013

Understanding student weaknesses

A Harvard University study found that 95% of people believe the Earth's seasons are caused by its distance from the sun. However, scientists know it's due to the axis tilt and resulting sunlight duration. The study showed that better teachers who predicted students' wrong answers helped them learn more.

SourceHarvard University·JournalAmerican Educational Research Journal·DateMay 2, 2013

Robotic insects make first controlled flight

Researchers at Harvard University have successfully demonstrated the first controlled flight of a robotic insect, weighing less than a tenth of a gram, which achieves vertical takeoff, hovering, and steering. The achievement marks the culmination of over a decade's work in micromanufacturing and control systems.

SourceHarvard University·JournalScience·DateMay 2, 2013

Potential diabetes breakthrough

Researchers at Harvard University have discovered a hormone called betatrophin that increases insulin-secreting pancreatic beta cells by up to 30 times the normal rate. This could lead to a more natural regulation of insulin and reduced complications associated with diabetes.

SourceHarvard University·JournalCell·DateApr 25, 2013

Reinventing drug discovery

A new stem-cell based drug screening technology has identified a compound that prolongs the life of motor neurons in both normal and ALS-affected cells. The study found kenpaullone, which inhibits HGK, an enzyme associated with motor neuron death, to be more effective than two failed drugs in human clinical trials.

SourceHarvard University·JournalCell Stem Cell·DateApr 18, 2013

Clinging to crevices, E. coli thrive

Researchers found that E. coli flagella can act as biological grappling hooks, reaching deep into nanoscale crevices and latching the bacteria in place. This ability to stick to any surface at all allows bacteria to survive on medical implants.

SourceHarvard University·JournalProceedings of the National Academy of Sciences·DateApr 10, 2013

Online learning: It's different

Harvard researchers found that students who took short tests between online lecture segments had reduced mind-wandering, tripled note-taking, and improved material retention. The testing act as an incentive for students to pay closer attention.

SourceHarvard University·JournalProceedings of the National Academy of Sciences·DateApr 4, 2013

An inside look at carnivorous plants

Researchers at Harvard Forest discovered a diverse array of organisms inside carnivorous pitcher plants, including bacteria, midge larvae, and rotifers. The study found that predator-prey interactions play a key role in shaping the food web, with removing one species affecting others.

SourceHarvard University·JournalOikos·DateApr 2, 2013

A new way to lose weight?

Researchers at Harvard University have discovered that drastic changes in the gut microbes of mice occur following gastric bypass surgery, resulting in rapid weight loss. The study suggests that manipulating microbial populations could become a valuable tool to address obesity.

SourceHarvard University·JournalScience Translational Medicine·DateMar 27, 2013

Measuring the magnetism of antimatter

A team of Harvard scientists has successfully measured the magnetic charge of single particles of matter and antimatter, achieving a significant increase in accuracy for antiprotons. This breakthrough could provide new insights into the nature of matter and help address fundamental questions about the universe.

SourceHarvard University·JournalPhysical Review Letters·DateMar 25, 2013

Guiding responsible research in geoengineering

Geoengineering experts Edward Parson and David Keith propose a new structure for regulating geoengineering research to manage climate change risks. They advocate for scientific self-regulation, government authority, and international coordination to ensure low-risk research advances while addressing public concerns.

SourceHarvard University·JournalScience·DateMar 14, 2013

One gene, many mutations

Researchers have found that nine separate mutations within a single gene in deer mice result in changes to their camouflage, illustrating the power of small genetic changes. The study suggests that natural selection acts on many small genetic changes to produce rapid and dramatic adaptations.

SourceHarvard University·JournalScience·DateMar 14, 2013

Linking insulin to learning

Harvard researchers show that insulin-like peptides play a crucial role in regulating learning and memory by fine-tuning neuronal activity. The study reveals a bidirectional regulation of learning, with some peptides inhibiting learning while others facilitate it.

SourceHarvard University·JournalNeuron·DateFeb 26, 2013

Rethinking wind power

Research suggests that large-scale wind farms' generating capacity may peak at between 0.5 and 1 watt per square meter, significantly lower than previous estimates. This limitation could impact the feasibility of scaling wind power to meet a third of global energy needs within the next half-century.

SourceHarvard University·JournalEnvironmental Research Letters·DateFeb 25, 2013

Robots with lift

Soft robots designed by Harvard researchers can leap up to a foot in the air using small explosions of methane and oxygen. This fast-acting system could aid in search and rescue missions. The robots' jumping ability is made possible by a simple valve system and the brief, high-energy explosion.

SourceHarvard University·JournalAngewandte Chemie·DateFeb 13, 2013

The tales teeth tell

Researchers at Harvard University challenged long-held assumptions about juvenile primate tooth development and weaning by studying chimpanzees in the wild. The study found that many young chimps continued to nurse as much, if not more, than before after their first molar erupted.

SourceHarvard University·JournalProceedings of the National Academy of Sciences·DateJan 28, 2013

Bioinspired fibers change color when stretched

Researchers at Harvard University have developed color-changing photonic fibers inspired by nature, which can pass through a full rainbow of colors as they're stretched. The fibers' superior mechanical properties make them versatile for various applications, including smart sports textiles and sensors.

SourceHarvard University·JournalAdvanced Materials·DateJan 28, 2013

An early sign of spring, earlier than ever

Researchers found that record warm temperatures in 2010 and 2012 resulted in the earliest spring flowering in the eastern United States. Spring is arriving much earlier today than it has in the past, with plants flowering over three weeks earlier than when they were first observed.

SourceHarvard University·JournalPLOS ONE·DateJan 16, 2013

Counting the twists in a helical light beam

Researchers at Harvard University have created a new device that can detect and distinguish between different types of twisted light waves, which can add an extra level of multiplexing to communication systems. This could potentially increase the rate of data transmission over limited bandwidth.

SourceHarvard University·JournalNature Communications·DateJan 8, 2013

Helping the nose know

Researchers describe how feedback mechanism works by identifying where signals go and which neurons receive them. The study reveals that higher brain regions communicate with lower parts of the brain on a near-constant basis, helping to interpret olfactory information.

SourceHarvard University·JournalNeuron·DateDec 19, 2012

Greener storage for green energy

A team of Harvard engineers and chemists are working on a one-year, $600,000 grant from ARPA-E to develop a new type of storage battery that uses eco-friendly small organic molecules. The technology aims to make stationary energy storage cost-effective, enabling wind and solar power to displace fossil fuels more widely.

New device hides, on cue, from infrared cameras

Researchers at Harvard University have developed a new device that can absorb 99.75% of infrared light on demand, using a tunable material with exceptional optical properties. The device has wide-ranging applications in thermal imaging, spectroscopy, and energy harvesting.

SourceHarvard University·JournalApplied Physics Letters·DateNov 26, 2012

Uncovering complexity

A single type of neuron in Caenorhabditis elegans nerve cord encodes an entire sensorimotor loop, with feedback driving motion itself. The discovery reveals a sophisticated system allowing the worm to organize its movements through proprioceptive feedback.

SourceHarvard University·JournalNeuron·DateNov 21, 2012

Injectable sponge delivers drugs, cells, and structure

Researchers at Harvard University have developed a biocompatible gel-based sponge that can be molded to any shape, loaded with drugs or stem cells, and delivered via injection. The sponge pops back to its original shape once inside the body, gradually releasing its cargo before safely degrading.

SourceHarvard University·JournalProceedings of the National Academy of Sciences·DateNov 13, 2012

Solving a biological mystery

Harvard scientists have solved the long-standing mystery of how some insects form germ cells, discovering that a cricket's oskar gene is far older than previously thought. The team found that the gene emerged in their last common ancestor and likely originated in the nervous system before being co-opted for germ cell formation.

SourceHarvard University·JournalCurrent Biology·DateNov 1, 2012

Assembly not required

Researchers at NYU, Harvard, and Dow Chemical develop a method to enhance colloidal dispersions, creating particles that spontaneously assemble into structures resembling molecules. This enables the design of complex 3-dimensional structures vital for advanced optical materials.

SourceHarvard University·JournalNature·DateOct 31, 2012

Unearthing a hidden dietary behavior

A new Harvard study found over half of people in northeastern Madagascar engage in geophagy, a widespread behavior previously thought to be non-existent. Researchers also discovered high rates of geophagy among men and young children, contradicting earlier studies that linked the practice mainly to pregnant women or adolescents.

SourceHarvard University·JournalPLOS ONE·DateOct 24, 2012