Researchers identified TP63 as a master regulator promoting immune evasion and affecting immunotherapy efficacy in squamous cell carcinoma. Inhibition of TP63 improves CD8+ T cell infiltration and tumor killing, offering a potential strategy to enhance anti-tumor immunotherapeutic effects.
Researchers created a novel composite material by adding Sm2O3 micron plates to boron-containing polyethylene, improving thermal stability, mechanical strength, and radiation shielding properties. The material showed excellent performance in blocking neutron and gamma radiation, with up to 98.7% blockage at 15 cm thickness.
Researchers developed a unique wristwatch with a built-in sweat sensor that continuously monitors potassium, sodium, and calcium ions in human sweat. The device boasts excellent stability and reliability, tracking the ions for over 6 months.
Researchers developed a high-efficiency hollow-core fiber optic cable with a larger core diameter and anti-resonant structure, improving coupling transmission efficiency and damage threshold. The cable system demonstrates excellent performance in transmitting high-energy pulsed lasers for medical applications.
Researchers discovered three unique multiferroic materials exhibiting ferrimagnetism and ferro/antiferroelectricity at room temperature. The materials are achieved through d-p spin coupling combined with center-symmetry-breaking organic heterocycles in 2D metal-organic frameworks.
Researchers at Hefei Institutes of Physical Science developed a novel design for line-filtering capacitors featuring 'Matryoshka doll' structure electrodes, which provide a powerful and space-saving solution. The devices exhibit exceptional impedance phase angles, low resistance-capacitance time constants, and high specific capacitance.
Scientists achieved stable magnetic skyrmion bundles in a chiral helimagnetic material at room temperature and zero magnetic field, overcoming previous challenges. This breakthrough could enhance the development of topological spintronic devices.
Scientists developed a new method to enhance X-ray detection by incorporating out-of-phase CsPb2Br5 perovskite into CsPbBr3 bulk material, achieving high sensitivity and low detection limit
A research team has developed an underwater mass spectrometry technique that enhances dissolved methane detection sensitivity by over 500 times, improving our understanding of oceanic methane flux and its impact on climate change. This breakthrough enables more accurate global climate research, plume tracking, and cold seep discovery.
The research team successfully synthesized high-quality two-dimensional CrVI6 single crystals and conducted precise micro-area magneto-optical Kerr effect measurements, revealing distinctive 'cat ear'-shaped prominences in the MOKE hysteresis loop. The findings hold significant promise for advancing our understanding of topological mag...
Researchers developed a novel 3D microelectrode chip for on-site determination of soil nutrients, achieving low detection limits and high resolution in ion separation. This innovation enables farmers to rapidly and precisely determine nutrient ions, guiding precise fertilization practices.
Researchers developed DNA-aptamer based SERS probes to study immune system biomarkers related to bioprocesses in cancer cell metabolism. The results revealed that PD-L1 expression varies depending on cell metabolism and the presence of certain signaling molecules.
Researchers develop novel method to prepare carbonized polymer nanodots emitting multi-color ultra-long Room-temperature phosphorescence from blue to green. The resulting materials exhibit high quantum yield and resistance to photobleaching, holding great promise for security and data protection applications.
Researchers developed a novel pan-sharpening method based on wavelet high-frequency information, achieving outstanding performance in image fusion. The approach integrated two key modules and demonstrated effectiveness across various datasets, including World View-II and World View-III.
Researchers have designed iron-based nanocomposite materials that combine galvanic reactions and nanoconfinement effects to efficiently remove trace Cr(VI) from acidic or alkaline water. The CnZVI/Cu composites show great promise for practical applications in heavy metal pollution remediation.
Scientists discovered a fast and reproducible strategy to control the oxidation of spiro-OMeTAD, improving its conductivity and energy level position. The approach resulted in a high photoelectric conversion efficiency of 24.5% with stable performance under various conditions.
Researchers developed a spectral resolution enhancement method based on linear prediction theory to expand FTIR technology's application in detecting multi-component ultra-low concentration trace substances. The method effectively enhanced spectral resolution, achieving a relative error of 0.28% in spectral feature absorption bands.
Researchers investigate the role of neighboring adsorbates and quantum tunneling in hydrogen diffusion on graphene surfaces. Quantum tunneling plays a key role in diffusion at room temperature and below, with contributions still present at higher temperatures.
Researchers have synthesized an ultrafine Ce(OH)3 nanoparticles coating on CoFe-LDH nanowires, producing numerous stable active interfaces. This results in enhanced catalytic performance and stability, particularly compared to commercial RuO2 anodes.
Researchers developed a concentration-independent pressure sensing method using two-color laser absorption spectroscopy for high temperature environments. The new method eliminates the effect of molecular concentration on gas pressure measurements, enabling accurate pressure measurement at temperatures up to 1300 K.
Researchers created a compact MFM system that can image air-sensitive materials without surface protection coatings, addressing a major challenge in magnetic materials research. The system provides a controlled environment for precision and reliability, revealing intrinsic magnetic structures.
Researchers developed a self-confined solid-state dewetting mechanism to efficiently pattern non-closely packed gold nanoparticle arrays, enabling two-orders-of-magnitude increase in sensitivity for plasmonic sensing of molecular interactions. This breakthrough paves the way for portable devices with sensitive biosensing capabilities.
Researchers introduced a new network to enhance underwater images while considering memory and computational power limitations. The Multi-scale Feature Modulation Network (MFMN) achieves better performance with reduced parameters and computational costs.
Researchers developed bimetallic copper-nickel phosphide electrocatalysts that exhibit rich heterointerfaces, boosting electron transfer and improving NO3 RR efficiency. The study reveals a successive hydrodeoxygenation pathway and contributes to understanding the electrocatalytic process for sustainable ammonia synthesis.
Research team introduces metal-free nanozyme based on graphene quantum dots for highly efficient tumor chemodynamic therapy. The GQDs have been shown to possess impressive peroxidase-mimicking activity and selectively target tumors with minimal side effects.
Researchers introduced a new strategy to prepare ultrahigh density copper single atom enzymes, alleviating the generation of ·OH dilemma in tumor microenvironment. The resulting Cu1 SAEs exhibited remarkable self-cascade catalytic activities, leading to up to 89.17% tumor inhibition rates.
Researchers from Hefei Institutes of Physical Science discovered a new superconducting material called (InSe2)0.12NbSe2, which possesses a unique lattice structure and a high transition temperature of 11.6 K. This material exhibits an impressive critical current density, comparable to high-temperature superconductors.
A new code, TransROTA, has been developed to analyze plasma rotation and transport properties in tokamaks, including EAST. The code improves the prediction accuracy of unmeasurable ion velocities and allows investigations of plasma physics.
Researchers at Hefei Institutes of Physical Science used SERS to study the interactions between aromatic molecules and Au surfaces, revealing new insights into interfacial interactions. The results show a strong potential for SERS in detecting aromatic molecules with high sensitivity.
Researchers introduce oxygen vacancies into NH4V4O10 nanobelts to boost aqueous zinc ion battery performance. This defect engineering enhances ion and charge transfer kinetics, reduces diffusion barriers, and increases electrochemical surface reactivity.
Researchers reveal novel magnetoresistance and Hall effect in Fe5-xGeTe2 nanosheets, attributed to stripe domain structure. The study shows significant thickness dependence of magnetic properties on macroscopic electrical transport characteristics.
Researchers developed a high-resolution cell type deconvolution mode method using CIBERSORTx to analyze pooled skin bulk transcriptome data, identifying eight different skin cell types. This allowed for more accurate analysis of gene expression changes post-burn injury and exploration of new targets for clinical wound healing.
Researchers developed a nanoenzyme called PCMF that responds to the tumor microenvironment, providing enhanced imaging contrast and inducing apoptosis in cancer cells. PCMF also exhibits photothermal conversion capability for combined therapy.
Researchers discovered that adding disodium maleate to the electrolyte of aqueous zinc-ion batteries can inhibit dendrite growth and improve cyclability. The study demonstrated ultralong cycling lifespans of over 3200 hours and high Coulomb efficiency, making this a promising strategy for achieving stable metal anodes.
A research group led by Prof. XIE Pinhua unveiled the source and transport mechanisms behind an episode of ozone pollution observed in Hefei, a city in the Yangtze River Delta region of China. The study integrated stereoscopic detection techniques with numerical models to analyze the transport process and source attribution of ozone.
A research group at Hefei Institutes of Physical Science developed the first Tesla class iron-based superconducting coil for high field application. The coil successfully generated a central magnetic field strength of 1.03 T, surpassing all previously reported performance tests of iron-based superconductor coils.
Researchers created programmable photothermal actuators mimicking plant tendril movement, exhibiting large deformation and rapid response. The actuator's versatility paves the way for development of soft robots and bionic systems.
Researchers developed a three-phase catassembly method to assemble 10 nm gold nanoparticles into large-area, high-density plasmonic multilayers. These multilayers exhibited remarkable sensitivity and stability in SERS detection.
Researchers discover threefold coordinated germanium in a GeO2 melt for the first time using high-temperature Raman spectroscopy and DFT computation. This finding changes the traditional viewpoint of germanium oxide structure and provides new insights into germanate melts.
A research team developed an efficient method to capture high-resolution images of moving objects using Fourier ptychographic imaging technology. By leveraging image registration techniques and advanced algorithms, they successfully reconstructed high-resolution images equivalent to those obtained with large-aperture detection, overcom...
Researchers have synthesized an oxygen-coordinated Fe single atoms and atom clusters catalyst, demonstrating superior electrocatalytic performance toward H2O2 production and biomass upgrading. The catalyst successfully coupled with the electro-Fenton process, leading to high-rate ethylene glycol conversion and formic acid selectivity.
Researchers propose a parallel planar heterojunction strategy for high-efficiency solar cells using antimony trisulfide as an absorber, achieving an impressive 8.32% efficiency. The approach simplifies material selection and device preparation by enabling the sequential depositions of multiple layers.
A research team developed a novel interfacial molecular bridge strategy to enhance the performance of perovskite solar cells. The strategy redistributed localized electrostatic potential by employing ammonium cations as a molecular bridge, improving device performance and carrier extraction.
Researchers developed a novel method, BELIVE, to trace cancer origins using DNA methylation profiling, improving accuracy for cancer of unknown primary sites (CUP) patients. The approach achieved high sensitivity rates of 81% and 93%, outperforming traditional immunohistochemistry methods.
A new study explores the optical properties of hollow cirrus clouds to enhance lidar data interpretation. The researchers developed a method to distinguish between solid and hollow ice crystals in cirrus clouds using the Cloud Particle Imager.
By introducing protons into the material, researchers successfully transitioned from ferromagnetism to antiferromagnetism at room temperature. This achievement has significant implications for the development of compact and non-volatile spintronic devices.
Researchers successfully monitored the diffusion behavior of a single molecule using SERS technology, enabling real-time analysis. The study found that crystalline violet molecules can be confined in sub-nanometer space, providing insights into molecular interactions and chemical reactions.
Researchers developed a novel method for extracting DNA from trace evidence samples, outperforming commercial reagent kits. The technique used modified lysis buffer and chitosan coated magnetic beads, achieving a detection limit of 10 cells.
Researchers have proposed a novel SERS substrate by intercalating single-atom-layer gold clusters into bilayer 2H-TaS2, achieving two orders of magnitude enhancement. The team found that the d-orbital electrons on the Au surface couple with neighboring 2H-TaS2, creating a strong local electromagnetic field.
Researchers developed a new biomimetic metal organic framework (Bio-MOF) that exhibits efficient absorption of electromagnetic waves. The Bio-MOF, called BSA@Mil-100, demonstrated significant improvements in microwave absorption performance compared to traditional materials.