Researchers have developed a new cytometry platform to detect rare cells in blood with high throughput and low cost. The technique uses magnetic bead labelling and alternating magnetic fields to enrich and detect target cells, achieving a limit of detection of 10 cells per millilitre.
Researchers at Caltech Optical Imaging Laboratory created a technique to break the acoustic diffraction limit in PACT by localizing single dyed droplets flowing in blood vessels, achieving six-fold finer resolution. The droplets provide excellent tracers for super-resolution imaging and enable tracking of blood flow speed.
Researchers developed Bright-field Holography to overcome limitations of holographic 3D imaging. The method combines the image contrast advantage of bright-field microscopy with the snapshot volumetric imaging capability of holography, allowing for rapid creation of images equivalent to those from a bright-field microscope.
Harmful algal blooms have become a serious problem for marine life, affecting humans and wildlife. UCLA researchers created a new flow cytometer that analyzes water samples instantly, providing real-time insight into algal bloom locations and severity.
Researchers used UV laser photolysis to improve diamond synthesis by suppressing unwanted side products. The technique promotes faster and better-quality diamond growth, opening up new possibilities for material synthesis.
Researchers at Ohio State University describe a new semiconductor LED made with GaN-based materials that could enhance LED solid state lighting without significant changes to manufacturing facilities. The breakthrough uses quantum-mechanical tunneling to create 'holes' for radiative recombination, reducing energy losses and self-heating.
Researchers develop a new spectrometer to analyze single living cells in situ, providing mechanical and chemical maps of the system. The study reveals that oncogene expression causes significant softening in cells, making them more invasive.
A new polarization-dipole azimuth-based super-resolution technique has been proposed, addressing a long-standing debate on the role of fluorescence polarization in super-resolution imaging. The technique uses SDOM technology to improve spatial resolution and detection accuracy, revealing interesting findings in biological samples.