A new Roundtable discussion in Health Equity explores the results of the NCHE's Heart of America Annual Survey, finding over 80% of respondents want a unifying leader. The expert panel discusses the power of racial healing and overcoming racism in politics and policy-making.
The metaverse offers a view into a future where human interaction transcends physical boundaries. Key findings include the potential for virtual reality to enhance human experience, but also highlight challenges in designing healthy digital spaces that promote positive interactions.
Panel discussions examine strategies to improve maternal health outcomes and collect accurate data on race, ethnicity, and language. Health systems can make changes to ensure equitable care by deploying accurate data collection methods.
The use of race and ethnicity in clinical algorithms can lead to biased treatment plans and perpetuate health inequities. Researchers explored the effects of race-based medicine on patient outcomes, revealing a self-fulfilling prophecy of racial reasoning that reinforces ideas about racial differences.
A study published in Facial Plastic Surgery & Aesthetic Medicine found that ChatGPT outperformed expert plastic surgeons in answering preoperative and postoperative patient questions. The AI tool received significantly higher ratings for completeness and overall quality.
A new study found that children with persisting symptoms after mild traumatic brain injury exhibited ongoing cerebral microstructural changes. The researchers used brain MRI-based metrics to detect these changes, which were more pronounced in symptomatic individuals than healthy controls.
A new review article highlights significant milestones in gene therapy for rare diseases, improving efficacy and safety. However, challenges remain to make this transformative approach widely available.
A new study found that neuroinflammation is a key feature of the brain response to blast exposure, affecting regions associated with memory retrieval, executive functioning, and sensory processing. Increased blast exposure also relates to reductions in volume and thickness of brain structures.
A new report highlights the need for improved antibiotic stewardship in outpatient telemedicine settings, where up to 28% of antibiotics are prescribed unnecessarily. The study's findings suggest that incorporating CDC core elements can optimize antibiotic use and reduce adverse events.
The American Thyroid Association has appointed Dr. Trevor E. Angell as the new Editor-in-Chief of Clinical Thyroidology. Dr. Angell succeeds Angela M. Leung and aims to continue the journal's upward trajectory. He brings expertise in thyroid diagnosis and treatment, having published research on thyroid nodules and molecular testing.
Researchers used a robotic system to test the repeatable healability of a self-healing actuator, finding that it can endure up to 53 cycles before suffering permanent damage. The study aims to prevent soft robot actuators from being disposed due to permanent damage.
The new clinical protocol provides detailed practical clinical management guidelines for mothers with SUD, emphasizing individualized care plans and ongoing postpartum care. The recommendations aim to promote breastfeeding benefits while addressing the complexity of substance use in lactating women.
A new article in OMICS: A Journal of Integrative Biology reports on an international group project that engaged 72 high school students from 32 countries in research-based life sciences learning. The project fostered collaboration, intercultural exchange, and collective problem-solving among participants.
A new study shows that closed-loop use in type 1 diabetes during pregnancy leads to improved glycemic control and reduced risks. Women using closed-loop technology reported better sleep and fewer worries about their baby's health.
Researchers develop novel combinatorial treatment strategy to reduce and overcome chondroitin sulfate proteoglycan's inhibitory effects on neuronal regeneration. The approach stimulates a good measure of recovery in paralyzed rats, paving the way for clinical translation.
Researchers examined violence, bullying, lifetime discrimination, microaggressions, and military sexual trauma among SGM adults, revealing high prevalence rates and disparities. The studies call for addressing intersecting experiences of stigma and structural oppression to improve health outcomes.
A new study found that delivering gene therapy to the cerebrospinal fluid directly corrects gene mutations causing CLN2 disease, showing potential therapeutic effects. In nonhuman primates, TPP-1 activity increased significantly after treatment, providing hope for families affected by this fatal childhood disorder.
A comprehensive review explores how industrial biotechnology and biopharmaceutical manufacturing leverage similar frameworks for efficient biochemical production. Advances in synthetic biology, genetic engineering, and high-throughput screening have contributed to rapid progress in new product development.
A special focus issue of Journal of Neurotrauma highlights the latest findings of North American Clinical Trials Network on improving outcomes for individuals with acute spinal cord injury. The issue includes studies on the benefits of early surgery, key results from a Riluzole study, and trends in corticosteroid use.
The special issue highlights three pillars of focus: leadership/employees/culture, patient care equity, and community health and policy advocacy. Studies demonstrate the effectiveness of stakeholder collaboration and learning collaboratives in reducing racial disparities.
Researchers have engineered an AAV vector to target brain vascular pericytes and smooth muscle cells, potentially treating conditions like Alzheimer's disease and Parkinson's. This breakthrough could revolutionize gene therapy by delivering genes directly to the brain's blood vessels.
A new study found that only 43% of pregnant women with lower back and pelvic girdle pain reported their symptoms to healthcare providers. Of those who did report the pain, 80% received effective treatment. Healthcare providers should ask about lumbopelvic pain in pregnant patients, especially if it disrupts daily activities.
A study found that many incarcerated women trade or barter for menstrual products, with 29.5% having to do so. The lack of access led to negative health consequences in nearly a quarter of the women involved.
Two vaccines to protect against RSV are now available for those over age 60, providing high levels of protections against the virus. The vaccines were developed by Glaxo SmithKline and Pfizer and have been approved by the US Food and Drug Administration.
A recent editorial statement emphasizes the need for love, support, and acceptance over misinformation for LGBTQ youth. The Journal Editor-in-Chief highlights the organized and well-funded efforts to distort science and dehumanize transgender individuals, limiting their access to healthcare.
A new study investigated the use of positron emission tomography (PET) with radiotracer (18F)-Flortaucipir to detect chronic traumatic encephalopathy (CTE) in former professional American-style football players. The study found no significant differences in (18F)-FTP uptake between former players and age-matched male control participan...
A comprehensive review article reviews the status of biobased succinic acid production using microbial metabolically engineered microorganisms. The article highlights key findings on titer, yield, and productivity achieved by various microorganisms.
New review explores MDXX drugs' potential as novel treatments for ASD, focusing on therapeutic efficacy and safety. The study highlights the importance of balancing these factors to develop effective and relatively safer molecules for ASD treatment.
This special issue of JICM examines the opportunities and challenges of traditional, complementary, and integrative medicine in global public health. The research showcases the potential of TCIM approaches to fulfill the Declaration of Astana's promise to improve global health.
Recent studies show that continuous glucose monitoring (CGM) is effective in improving glycemic control, reducing hypoglycemia risk, and increasing access to diabetes technologies. The technology has the potential to replace self-monitoring of blood glucose for insulin-requiring patients and become a standard for managing Type 2 Diabetes.
A new study highlights the importance of reproductive health counseling for women with congenital heart defects (CHD), particularly those with disabilities. Women with CHD and disabilities are more likely to receive advice on avoiding pregnancy due to their condition, emphasizing the need for tailored care.
A special issue of Health Equity journal explores ways to promote diversity, equity, and inclusion in healthcare for veterans. Research highlights successful initiatives, such as a biweekly Diversity Equity and Inclusion Working Group meeting, and a 5-fold increase in women Veteran enrollment in the VA Million Veteran Program.
Researchers identified genes for virulence and antimicrobial resistance in two bacteria that co-occur with C. difficile, posing a threat to human health. The study provides new insights into the development of antimicrobial resistance and offers potential treatment strategies.
A new study demonstrates that subretinal delivery of AAV-RPE65 gene supplementation increases RPE65 isomerase activity and recovers chromophore 11-cis retinal after bleaching in mice with D477G RPE65 mutation, providing initial proof-of-principle data for gene supplementation as a treatment.
A new study published in Journal of Women’s Health reveals racial disparities in outcomes for pregnant and postpartum veterans and their infants, with Black veterans experiencing higher rates of postpartum re-hospitalization and low-birth-weight infants. The findings underscore the need for further research to address health equity gaps.
A survey of over 40 experts found that many panelists infrequently use prognostic calculators and feel that improving consensus on acceptable neurological outcomes would be beneficial. Most panelists believed that a vegetative state or lower severe disability could justify withdrawing care.
A new study found that hysterectomy, oophorectomy, and tubal ligation are associated with an increased risk of cardiovascular disease. The strongest association was seen among women who underwent surgery before age 50.
Researchers developed a size exclusion chromatography (SEC) method to measure empty capsids in gene therapy programs, outperforming other analytical methods. The study found SEC-MALS to be linear, accurate, and precise, providing a robust analytical technique for advancement of gene therapy programs.
A new study has shown that women are underrepresented in late-breaking cardiovascular clinical trials (LBCT) presented at national meetings. LBCT can have an impact on novel drug and device approvals, intervention indications, and patient management.
A new study reveals racial and rural disparities in telehealth utilization among Medicare beneficiaries in Arkansas. The association between chronic conditions and telehealth use was strongest among White and rural individuals, while urban and non-Hispanic Black or African American beneficiaries showed weaker associations.
A new study found that lower health literacy was significantly associated with non-adherence to antihypertensive medication among Black Medicaid beneficiaries. The study highlights the importance of providing literacy assistance and health education to promote healthy behaviors.
Researchers evaluated six AAV vectors in 12 preclinical liver models to identify the most relevant combination for safe and efficient gene therapy. The study proposes using multiple models to provide a more complete picture of vector function, informing clinical decisions.
Researchers have developed a bioengineered AAV3B capsid variant with improved transduction to human liver cells and reduced seroreactivity to human serum samples. The variant, AAV3B-V04, demonstrates enhanced hepatocyte tropism and immune evasion, making it a promising candidate for gene therapy.
A new study evaluated the effect of hybrid-closed loop Control-IQ technology on time-in-range, mean glucose, hyperglycemia metrics, and HbA1c levels. The technology showed significant improvements, particularly in participants with poor baseline glycemic control.
Expert panelists emphasize need to redefine measures and represent historically excluded populations in data collection. They highlight efforts to build data capacity in under-resourced communities and enhance community involvement.
The NCATS Platform Vector Gene Therapy (PaVe-GT) program utilizes FDA guidance to prepare applications for Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD), stimulating gene therapy development. The PaVe-GT program has already helped receive ODD and RPDD designations for a gene therapy product treating PCCA-r...
A new study found that veterans with traumatic brain injury (TBI) do not have a higher risk of developing Alzheimer's disease. Researchers measured biomarkers for Alzheimer's disease and glucose metabolism in TBI veterans compared to those without TBI. The study suggests that other factors may contribute to the increased risk of dement...
Researchers used a monoclonal antibody to reduce circulating IgG levels, allowing for successful gene delivery to the liver and heart via systemic AAV-based gene therapy in mice and non-human primates. The strategy has potential to circumvent neutralizing antibody limitations and expand gene therapy accessibility.
The Academy of Breastfeeding Medicine has released new guidelines to help parents manage night-time breastfeeding in young infants. The guidelines emphasize the importance of mothers sleeping close to their babies and taking measures to minimize nighttime feedings, promoting a more responsive and baby-led approach to breastfeeding.
A recent study analyzes Twitter conspiracy theories about Bill Gates' role in the COVID-19 pandemic, revealing they are highly dynamic and interconnected. The findings suggest that believing one conspiracy theory can reinforce another, leading to increased sharing behaviors online.