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Massachusetts Institute of Technology


New way to turn genes on

Researchers at MIT have successfully turned on any desired gene in living cells using the CRISPR/Cas9 system. This breakthrough enables scientists to study gene function and identify genes involved in diseases, such as melanoma. The new method has also been used to screen for genes that confer resistance to cancer drugs.

Losing air

Researchers found that tens of thousands of small impacts could efficiently jettison Earth's entire primordial atmosphere, while giant impacts would be less effective. The team's calculations suggest that the early Earth was likely devoid of its original atmosphere, with Venus and Mars also experiencing significant atmospheric loss.

Two sensors in one

New nanoparticles can perform magnetic resonance imaging (MRI) and fluorescent imaging simultaneously, allowing for the tracking of specific molecules produced in the body. The particles were demonstrated to detect vitamin C in mice, showing strong fluorescent signals where vitamin C is present but little MRI contrast.

SourceMassachusetts Institute of Technology·JournalNature Communications·DateNov 18, 2014

Recommendation theory

The MIT researchers' model assumes that large groups of ratings can be clustered together and described probabilistically. They found that just five clusters were enough to account for most of the variation in a population, suggesting that collaborative filtering yields nearly optimal predictions.

Pulling together the early solar system

A team of researchers has provided evidence that the early solar system's protoplanetary disk was shaped by an intense magnetic field, driving gas toward the sun at a rapid rate. The study analyzed a meteorite sample, extracting individual grains and measuring their magnetic orientations to determine the original magnetic field.

Atomic timekeeping, on the go

Researchers at MIT and Draper Laboratory have developed a new atomic timekeeping approach that could enable more stable and accurate portable atomic clocks. The system suppresses the AC Stark shift effect, allowing for smaller, less expensive devices with improved accuracy compared to current fountain clocks.

SourceMassachusetts Institute of Technology·JournalPhysical Review A·DateNov 12, 2014

Diagnostic exhalations

Researchers at MIT developed an algorithm that can accurately determine whether a patient is suffering from emphysema or heart failure based on carbon dioxide readings in their breath. The algorithm achieved an area under the curve of 0.98, outperforming traditional diagnostic methods.

SourceMassachusetts Institute of Technology·JournalIEEE Transactions on Biomedical Engineering·DateNov 6, 2014

New way to make batteries safer

Researchers at MIT have developed a new way to coat batteries with a special material that prevents them from conducting electricity after being swallowed. The QTC-coated batteries were found to not damage the gastrointestinal tract in animal tests, showing promise as a safer alternative.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateNov 3, 2014

Raising cryptography's standards

Researchers at MIT and Maynooth University developed a mathematical framework to calculate the minimum-security guarantees for any given encryption scheme. This allows information managers to make more informed decisions about how to protect data. The framework also applies to data privacy, enabling the modification or structuring of a...

Harnessing error-prone chips

Researchers at MIT have developed a new system, Chisel, that enables programmers to prioritize energy savings over computational accuracy in certain applications. The system uses a tool to help programmers evaluate the acceptable level of error and automatically assigns instructions to unreliable hardware components.

Projecting a robot's intentions

Researchers at MIT have created a new visualization system that projects a robot's intentions in real-time, enabling engineers to better understand and optimize their decisions. This technology has the potential to significantly improve the development of self-driving cars, package-delivering drones, and other autonomous vehicles.

Getting the salt out

Researchers at MIT and Saudi Arabia have developed a method to remove salt from produced water using electrodialysis, which can be economically viable for treating extremely high-salinity water. The technology could reduce the need for fresh water from other sources and minimize contaminated water disposal.

SourceMassachusetts Institute of Technology·JournalApplied Energy·DateOct 21, 2014

Why sign rights treaties?

A new study finds that autocratic leaders who sign human-rights treaties do so for domestic political maneuvering rather than economic gains. The researchers analyzed four core treaties and found no evidence of tangible material rewards for ratification.

SourceMassachusetts Institute of Technology·JournalInternational Studies Quarterly·DateOct 20, 2014

Mars One -- and done?

A team of MIT researchers assessed the Mars One mission's technical feasibility, highlighting the need for new technologies to keep humans alive on Mars. The study found that a system to remove excess oxygen and more advanced water extraction methods are required, among other innovations.

Nanoparticles get a magnetic handle

Researchers at MIT have achieved a long-sought goal of creating particles that can emit a colorful fluorescent glow and be precisely manipulated into position within living cells using magnetic fields. The new technology could enable tracking the position of nanoparticles as they move within the body or inside a cell, and manipulate th...

SourceMassachusetts Institute of Technology·JournalNature Communications·DateOct 9, 2014

Untangling how cables coil

Engineers at MIT and Columbia University developed a method to predict cable coil patterns using laboratory experiments, computer-graphics technology, and theoretical analyses. The research aims to help design better deployment strategies for fiber-optic cables and prevent transmission glitches and data loss.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateOct 3, 2014

High-speed drug screen

Researchers use zebrafish and rodents to identify efficient RNA delivery vehicles, a major breakthrough in disease treatment development. The technology enables the rapid testing of hundreds of drug-delivery systems, overcoming a significant bottleneck in biotech research.

SourceMassachusetts Institute of Technology·JournalIntegrative Biology·DateSep 30, 2014

Battling superbugs

Researchers use CRISPR genome-editing system to target specific genes conferring antibiotic resistance, resulting in 99% killing of resistant bacteria. CombiGEM technology rapidly identifies genetic combinations that sensitize bacteria to different antibiotics.

SourceMassachusetts Institute of Technology·JournalNature Biotechnology·DateSep 21, 2014

Run, cheetah, run

Researchers at MIT have created a robotic cheetah that can run at high speeds using an algorithm inspired by the biomechanics of real cheetahs. The robot's legs are programmed to exert a certain amount of force in the split second during which it hits the ground, allowing it to maintain speed and stability.