Researchers at the Mayo Clinic found that high-definition colonoscopy detected 29% more polyps than standard colonoscopy, with a 20% increase in detecting precancerous polyps. This study, conducted on 2,430 patients, marked the first comparison of these two methods in clinical practice.
Dr. Jay Smith, a Mayo Clinic physician, has received the first-ever PASSOR Legacy Award and Lectureship for his groundbreaking contributions to musculoskeletal physiatry. The award recognizes Dr. Smith's innovative approaches to patient care, education, and research in this field.
A new Mayo Clinic study has found that video capsule endoscopy is safe for patients with heart devices, contradicting previous FDA contraindication. The study, involving 84 patients, showed no complications or interference between the procedure and implanted cardiac devices.
Researchers found that Barrett's esophagus patients have comparable survival rates to the general population, with a 10-year overall survival rate of 68%. Esophageal cancer was not significantly more common among these patients.
A Mayo Clinic study found that Clostridium difficile infections are rising in outpatient settings, with a higher proportion of cases in younger populations. The study suggests that antibiotic use may be contributing to the increased incidence and severity of C. difficile infections.
Researchers at Mayo Clinic found that inflammation in the brain helps clear amyloid deposits, contradicting long-standing scientific belief. The study suggests that manipulating brain inflammation could be a potential therapeutic approach to treat Alzheimer's disease.
A new decision aid tool, developed by Mayo Clinic clinicians and designers, helps patients with type 2 diabetes make informed decisions about their medication. The tool, a set of cards, involves patients in the decision-making process and leads to better patient-centered care.
Researchers at Mayo Clinic have achieved an impressive 93% success rate in animal tests of non-incision, endoscopic ulcer repair using Natural Orifice Translumenal Endoscopic Surgery (NOTES). The technique, which minimizes physical impact on the patient, may soon be tested in human clinical trials.
Mayo Clinic researchers found that certain structural features within breast tissue can indicate a woman's individual cancer risk. The percentage of acini present per lobule at a given age indicates cancer risk. This method is more accurate in predicting risk for an individual than the Gail model.
A new study published in the October 2009 issue of Gastroenterology found that patients with moderate-to-severe active ulcerative colitis had a 41 percent reduction in colectomy after one year when treated with infliximab. Treatment with infliximab reduced the incidence of colectomy through 54 weeks by 41 percent.
A large study by Mayo Clinic researchers found that patients treated with radiotherapy after prostate cancer surgery experienced very few complications, contradicting concerns about toxicity and side effects. The study suggests that radiation treatment is an effective and safe option for patients with recurrent cancer.
A Mayo Clinic survey published in the New England Journal of Medicine found that most physicians agree on their professional obligation to address health policy issues and expand access to basic healthcare. However, some physicians oppose measures such as underinsuring patients or using cost-effectiveness data in treatment decisions.
A Mayo Clinic study found that distress and fatigue among medical residents significantly contribute to self-perceived medical errors. The research used standardized survey tools to measure burnout, symptoms of depression, sleepiness, and fatigue, and found that both factors increased the risk of errors.
Researchers developed an artificial neural network (ANN) to evaluate symptoms and predict endocarditis diagnoses. The ANN achieved high accuracy in distinguishing between infected and non-infected cases, eliminating the need for invasive transesophageal echocardiography.
A Mayo Clinic study has found two genes associated with good central nervous system repair in mice with multiple sclerosis. The identification of these genes may lead to the development of new therapies and a better prediction of patient outcomes.
Researchers at the Mayo Clinic have discovered that the lung cancer oncogene PKCiota is necessary for the proliferation of lung cancer stem cells. The study found that an agent called aurothiomalate substantially inhibits growth of these cancer stem cells, suggesting a potential new treatment target.
A team of researchers from Mayo Clinic and Harvard Medical School found that the protein FOXO3a, previously believed to prevent cancer development, can actually fuel tumor growth in certain situations. This discovery sheds light on the complex roles proteins play in cancer progression.
Researchers at Mayo Clinic have found that early stage cancers of the esophagus can be treated effectively with less-invasive, organ-sparing endoscopic therapy. This approach was compared to traditional surgical removal of the esophagus and showed comparable overall mortality rates.
Researchers at Mayo Clinic have discovered a single gene promoting development of essential tremor in some patients and Parkinson's disease in others. The study found a significant association between the LINGO1 gene variant identified in Iceland to both disorders, with mutations potentially responsible for five percent of patients.
Researchers at Mayo Clinic found high-dose ursodeoxycholic acid to be detrimental in treating primary sclerosing cholangitis. The six-year trial showed that serious adverse events were more common in the high-dose group, highlighting the need for further research on better treatment options.
Researchers analyzed 17,398 patient records and found only 14 real disease associations with MGUS, not 61 as previously reported. This finding may reduce unnecessary testing and treatment for patients with MGUS.
A new study found that relief of pain and improvement in function were similar in patients treated with vertebroplasty and simulated vertebroplasty without cement injections. The study raises questions about the procedure's long-term efficacy, suggesting that other factors may contribute to its benefits.
Researchers at Mayo Clinic found that children exposed to general anesthesia during C-section delivery have no higher risk of learning disabilities. Babies delivered via Cesarean with epidural anesthesia had a reduced risk of learning disabilities compared to those delivered vaginally or with general anesthesia.
Researchers at Mayo Clinic have discovered a mutated gene linked to restless legs syndrome, affecting 5-11% of the population. The study suggests that this genetic mutation may be a key factor in understanding the condition, which causes unpleasant sensations in the legs at rest.
Researchers successfully used induced pluripotent stem (iPS) cells to treat heart damage caused by infarction. The treatment restored heart muscle performance, stopped progression of structural damage, and regenerated tissue at the site of heart damage.
Mayo Clinic researchers found that prior exercise was significantly associated with milder impairments and better ability to care for oneself after a stroke. The study's lead investigator suggests that exercise can improve outcomes even if it doesn't reduce the risk of developing a stroke.
A new Mayo Clinic study found that clinical criteria for mild cognitive impairment are better at predicting Alzheimer's disease than a single memory test. The study identified individuals aged 70-79 years who were cognitively normal or had slight memory impairment as being most likely to develop Alzheimer's disease.
A Mayo Clinic study has developed a framework for MRI-based differential diagnosis of Alzheimer's disease, frontotemporal lobar degeneration, and Lewy body disease. The 'STructural Abnormality iNDex' or STAND-Map framework predicts an accurate pathological diagnosis 75 to 80 percent of the time.
The review examines the prevalence of prescription opioid addiction among patients and healthcare providers, citing risks and consequences. New approaches to minimize abuse and promote recovery are discussed, emphasizing the importance of awareness and treatment.
The Mayo Clinic Cancer Center has received a $28 million National Cancer Institute (NCI) funding grant for five years. This award extends the center's designation as a comprehensive cancer center, enabling it to continue delivering outstanding care and research programs across its three US sites.
Researchers at Mayo Clinic and University of California San Francisco have discovered a connection between DNA alterations on human chromosome 9 and glioblastoma. The study found that individuals with specific single nucleotide polymorphisms (SNPs) are 50% more likely to develop the aggressive brain cancer.
A Mayo Clinic study found celiac disease has become four times more common, with undiagnosed cases associated with a nearly quadrupled mortality risk. The study suggests increased awareness is needed among physicians and patients to diagnose the condition earlier.
A review in Mayo Clinic Proceedings suggests that deep brain stimulation (DBS) may be an effective treatment for hard-to-treat depression and obsessive-compulsive disorder (OCD). The therapy, which involves stimulating specific parts of the brain, has shown early results with a beneficial effect on these conditions.
Researchers used a combination of an immunotherapeutic agent called MDX-010 or ipilimumab with standardized hormone treatment and radiation therapy to treat advanced prostate cancer. The approach led to significant tumor shrinkage and cancer cell death, allowing surgery in two previously inoperable patients.
Researchers at Mayo Clinic have found a peptide that preserves and improves kidney function during heart failure, potentially reducing the risk of kidney damage. The new compound has been tested in laboratory and animal models and is expected to move into clinical trials next year.
Mayo Clinic is leading a six-year study to determine whether catheter ablation is more effective than drug therapy for treating atrial fibrillation. The trial will randomize patients over three years, examining effectiveness and safety of left atrial catheter ablation versus current state-of-the-art drug therapy.
Researchers at Mayo Clinic have found that bariatric surgery may be associated with an increased risk of fractures, particularly in the hands and feet. The study, which analyzed nearly 100 surgical cases over a 21-year period, showed that 21 individuals experienced 31 fractures within seven years after surgery.
A new study demonstrates the effectiveness of eculizumab in preventing antibody-mediated rejection in positive crossmatch kidney transplant patients. The treatment, which blocks the immune system's activation of the complement system, showed promising results with none of the treated patients developing antibody-mediated rejection.
A new DNA stool test has been developed by Mayo Clinic researchers to detect digestive cancers in multiple organs, including pancreas, stomach, and esophageal cancers. The test was shown to be highly sensitive, detecting cancers at each organ site with high accuracy.
Researchers at Mayo Clinic have developed new tests that significantly improve the detection rate of bile duct and pancreatic cancer, increasing it from 20% to 43%. The combination of cytology and FISH analysis was found to be more effective in diagnosing these cancers.
Researchers at Mayo Clinic found that low doses of carbon monoxide can reverse gastroparesis, a common complication in diabetes. The study showed that carbon monoxide normalizes gastric functioning without increasing oxidative stress or HO1 expression.
Researchers at Mayo Clinic have identified a novel molecular path linked to primary biliary cirrhosis, a disease affecting 1 in 2,500 Americans. The study found variants of two genes, interleukin 12A and interleukin 12RB2, strongly associated with the condition.
A Mayo Clinic study found that short preoperative team briefings can improve communication and reduce errors in cardiac surgery. The briefings were conducted prior to the first procedure of the day and resulted in a 53% reduction in miscommunication events.
Researchers at Mayo Clinic have found that patients with chronic lymphocytic leukemia (CLL) can tolerate high doses of green tea extract EGCG, leading to a significant reduction in lymphocyte count. The study also showed that many participants experienced regression of CLL symptoms, particularly those with enlarged lymph nodes.
Researchers redefine migraine as a potentially chronic disease, requiring a collaborative healthcare model with patients and professionals. This new understanding offers opportunities for personalized care and improved disease management.
A Mayo Clinic study reveals a history of child abuse significantly impacts the challenges faced by depressed inpatients, including increased suicide attempts and psychiatric hospitalizations. The research highlights the importance of aggressive approaches to prevent child abuse and stresses the need for more public health initiatives.
A Mayo Clinic study reveals that patients with bipolar disorder incur significantly higher specialty care costs compared to those with diabetes, depression, asthma, or coronary artery disease. Specialty care costs were especially high for bipolar patients, suggesting non-mental health provider-related expenses contribute to the disparity.
Researchers compared TV show crimes to real homicides and found significant differences in portrayal of alcohol use, relationships, and racial representation. The study highlights the need for accurate public health messages, as media influences individual health behaviors and perceptions.
Researchers at Mayo Clinic found that pazopanib stops new blood vessel growth, slowing aggressive differentiated thyroid cancer. The treatment showed promising results in about two-thirds of patients with fast-growing cancers that had spread to lungs and other organs.
A study published by Mayo Clinic researchers found that pregabalin decreases hot flash severity and frequency, offering a treatment option for women who cannot take hormonal therapies or antidepressants. The medication appears to have a similar benefit as gabapentin and newer classes of antidepressants, with a lower dosage requirement.