A Mayo Clinic study analyzed data from the Rochester Epidemiology Project and found a stable incidence of autism until 1988-1991, then increased with new diagnostic criteria and special education laws. Researchers identified 124 children meeting current diagnostic criteria for autism out of 3,000 with related diagnoses.
A Mayo Clinic study found that children with restless legs syndrome have a higher risk of family history and iron deficiency, which may be linked to the condition. The study examined 538 children and found that 72% had a family history of restless legs syndrome, with mothers being three times more likely to be affected.
Researchers tested devices outside of the body and found no interference, but warn that technology advances require continual testing for clinical safety.
A new blood test can accurately diagnose neuromyelitis optica (NMO), a debilitating inflammatory disease that destroys the protective myelin sheath around the optic nerve and spinal cord. Early diagnosis with this biomarker enables optimal therapies to be started sooner, potentially lessening the impact of the disease.
A population-based study of nearly 2,300 US adults found a significant link between gastrointestinal disorders and insomnia. The study suggests that irritable bowel syndrome is more common among people with sleep disturbances than those without.
Researchers found that a combination of thalidomide and dexamethasone is as effective as standard intravenous chemotherapy in treating newly diagnosed multiple myeloma. A newer analog, CC-5013 (lenalidomide), showed promise with fewer side effects.
Researchers used reactive hyperemia peripheral arterial tonometry (RH-PAT) to assess coronary endothelial dysfunction in patients. The study found a strong correlation between fingertip test results and coronary endothelial dysfunction, suggesting the fingertip test could be an effective screening tool for early heart disease.
Researchers at the Mayo Clinic have identified a potential biomarker for aggressive kidney cancer, which can help improve treatment outcomes by identifying patients at high risk of disease progression. The study found that high levels of B7-H1 molecule are associated with increased risk of cancer spread and mortality.
Urinary incontinence and abdominal pain are key symptoms of ovarian cancer, with crampy abdominal pain being the most common symptom. The study found that women often ignore or downplay these symptoms, leading to delayed diagnosis.
A new hysteroscopic sterilization technique has been shown to be less expensive than traditional laparoscopic tubal ligation, with patients typically leaving the hospital within an hour and recovering quickly. The method requires minimal sedation and no surgical incision, resulting in significant cost savings for patients.
A Mayo Clinic study found that patients with well-controlled epilepsy have a very low risk of injury from seizures. The study examined records of 247 patients and found that 80% of injuries were cuts or bruises that did not cause serious health consequences.
Researchers found that testosterone impairs T-lymphocyte function, leading to a weakened immune response in men. In contrast, females' immune systems are more active without significant levels of testosterone, making them more prone to autoimmune diseases.
A new study by Mayo Clinic suggests that the ketogenic diet can be safely initiated as an outpatient treatment for children with epilepsy, offering improved acceptability and comfort. The study found no significant differences in long-term seizure control or mental improvement between inpatient and outpatient groups.
A Mayo Clinic study found that physical training is more effective than amphetamine use in improving motor function after a stroke. The research team's experiment used brain-damaged rats to demonstrate the power of physical training in recovery.
The new Mayo Clinic research indicates that mycophenolate mofetil could help many more lupus patients, offering a potential alternative to existing treatments with fewer side effects. Currently, there is no curative treatment for SLE, and many medications used to treat this disease have considerable side effects.
Weight-reduction surgery patients are at risk of developing peripheral neuropathy, a condition causing pain, numbness, and weakness. Following nutritional guidelines and attending post-surgical care programs can help prevent nerve damage.
Researchers found that certain species of airborne fungus trigger abnormal immune responses, leading to congestion and inflammation in patients with chronic rhinosinusitis. The study suggests that reducing fungal exposure through treatments like nasal irrigations or antifungal medicines could provide relief.
Researchers at Mayo Clinic found that pyridostigmine improved patients' standing blood pressure and reduced symptoms without elevating blood pressure while lying down. The study showed significant results in reducing the need for other medications, particularly in those over age 70 with common causes like diabetes and Parkinson's disease.
Mayo Clinic has been awarded a major NIH contract to conduct genomic research on smallpox vaccination, utilizing its advanced genomics technology center and biostatisticians. The study aims to identify gene polymorphisms affecting susceptibility to infection and response to vaccination.
According to Dr. Broughton, most children reported missing are runaways or taken by noncustodial parents, not strangers. Children need to learn skills and confidence, not fear and avoidance. Parents can teach personal safety without causing unwarranted fear.
A new study by Mayo Clinic researchers demonstrates that eosinophils are required for mucus accumulation and lung dysfunction associated with asthma. Transgenic mice without eosinophils showed reduced or eliminated disease symptoms following allergen exposure, paving the way for novel therapies to treat and prevent asthma.
A new study published in Mayo Clinic Proceedings found that males are at a higher risk for ADHD than females, with low maternal and paternal education levels increasing the risk. Researchers analyzed birth certificates of children born between 1976 and 1982 and identified those with ADHD using medical and school records.
A study by Mayo Clinic researchers found that high-sensitivity C-reactive protein (hs-CRP) is associated with the presence of atherosclerotic plaques in the arteries, even if symptoms are absent. Elevated hs-CRP levels may indicate an increased risk of cardiovascular events like heart attacks.
Researchers successfully delivered a phosphorescent green protein from jellyfish to the eyes of laboratory cats, producing a permanent effect. The study demonstrates a potential gene therapy approach to treat glaucoma, a chronic disease affecting 70 million people worldwide.
A study led by Mayo Clinic cardiologist Veronique Roger found that cardiac rehabilitation can improve survival rates for heart attack patients by almost 50%. However, women and elderly patients were less likely to participate in exercise programs due to factors such as lack of transportation and support networks.
A recent study found that immediate statin therapy in hospitalized heart attack patients significantly reduced the risk of death and additional heart attacks. The study, which involved 3,605 patients at 260 medical centers, confirms earlier findings that early statin treatment is beneficial for heart health.
A recent study by Mayo Clinic researchers suggests that patients with minimal or no disability after 10 years of multiple sclerosis (MS) are unlikely to progress and may not need medication. However, those with higher disability scores may still experience worsening symptoms over time.
A study published in Mayo Clinic Proceedings found that intensive glucose management in ICU patients resulted in a significant reduction in mortality rates, with a decrease of 29.3% and the prevention of 49 deaths. The treatment involved monitoring blood glucose levels and administering insulin to prevent elevations.
A study reveals the tobacco industry's extensive efforts to shape journalists' coverage of secondhand smoke, a public health issue with significant mortality rates. The research highlights the need for increased scrutiny of media articles on this topic to ensure accurate public information.
MayoClinic.com empowers people to manage their health with useful and up-to-date information and tools from a team of over 2,000 physicians and scientists. The site is owned by Mayo Foundation for Medical Education and Research and serves as a dependable source of health information.
Scientists at Mayo Clinic develop novel approach to cancer vaccine that leverages inflammatory cell death to trigger a strong anti-tumor immune response, eradicating skin cancer tumors without triggering autoimmune disease. The breakthrough sheds light on a major obstacle in advancing cancer vaccine research from lab to human trials.
A new phase 2 study shows that combining cetuximab with irinotecan can resensitize tumors resistant to irinotecan, offering patients a new treatment option. The study's modest benefits in stopping cancer growth and improving patient response are seen as a step forward in treating colorectal cancer.
According to a study published in JAMA, aging populations have led to improved five-year survival rates for heart failure patients. Notably, women outlive men with heart failure by about 4 years, while treatment approaches can be refined to improve patient outcomes and reduce hospitalizations.
A new Mayo Clinic study finds that CABG surgery is not a risk factor for dementia, but patients may experience cognitive decline due to surgical complications. The study took an innovative approach by starting with dementia cases and comparing them to non-demented control groups.
A randomized study compared vitamin E and donepezil to placebo for delaying progression to Alzheimer's disease in patients with mild cognitive impairment. Patients treated with donepezil showed a modest delay in disease progression, but this effect was short-term.
Researchers at Mayo Clinic used a human antibody to stimulate dendritic cells and induce an immune response against malignant melanoma. The study showed that the antibody treatment resulted in consistently strong and often curative effects in mice, with 69% of treated mice being tumor-free.
Researchers at Mayo Clinic are investigating thalidomide's potential to combat multiple myeloma through various studies. The findings suggest that the risk of progression to the disease persists even after 30 years, emphasizing the need for ongoing clinical trials.
Mayo Clinic researchers discovered a gene, BubR1, that regulates physical aging and fertility. The study found that mice with low levels of the protein age prematurely and develop reproductive disorders.
A recent study found that nearly half of adults with hypertension also have high cholesterol, which can be treated with existing medications. However, many individuals are not receiving adequate treatment for their cholesterol problems, highlighting the need for aggressive management of both conditions to prevent cardiovascular disease.
A study of accidental sand burials reveals that respiratory asphyxia is a deadly hazard, especially for young children. Parents are urged to supervise their kids playing in the sand, while early extrication and airway management can significantly improve survival odds.
The Mayo Clinic discovery sheds light on the cellular mechanisms behind Non-Alcoholic Fatty Liver Disease (NAFLD), a growing global problem related to affluence and diet. Early signs include accumulation of fat in the liver, inflammation, and scarring, which can lead to impaired function.
A study of 2,115 male patients found that symptoms like urgency and weak urine stream are strongly associated with sexual dysfunction, but not sex drive. The findings may help researchers develop new treatments for both lower urinary tract symptoms and sexual dysfunction.
A study of 494 cancer patients found that specific genetic variants are associated with increased fatigue and distress, suggesting a possible link between genetics and quality of life in cancer patients. The research aims to develop personalized treatments tailored to an individual's genetic profile to improve their quality of life.
Researchers at Mayo Clinic found that frozen sperm are just as effective as fresh sperm in in vitro fertilization. The cumulative live birth rate was higher for frozen sperm, with a success rate of 53.1 percent compared to 51.6 percent for fresh sperm.
A seven-year international study involving 872 patients with colon cancer has resolved concerns about laparoscopic surgery, finding it to be as safe and effective as standard surgery. The study found similar rates of complications, cancer recurrence, and overall survival between the two groups.
The Mayo Clinic researchers have invented a nontoxic molecular probe that targets the brain regions containing amyloid plaques, enabling high-resolution MRI images in live mice and potentially human patients. The probe may also be used to evaluate new Alzheimer's therapies and provide early diagnosis.
A new measurement method and microenvironment evaluation technique have been developed to study spinal cord nerve regeneration. The findings extend earlier Mayo Clinic research, showing that a biodegradable scaffold can support axon growth under different experimental conditions.
A new study from the Mayo Clinic found that pyridostigmine improves standing blood pressure without increasing blood pressure when lying down, offering a safe treatment option for patients with orthostatic hypotension. The study involved 29 patients who were satisfied with the drug's effects, with 17 taking it as their primary treatment.
A Mayo Clinic study found that most children with juvenile dermatomyositis (JDM) carry a particular gene from their mother, triggering an immune response. The research suggests that maternal cells may play a role in the development of JDM, a rare condition that causes inflammation and muscle damage.
The study found that Dynamin-2, an enzyme involved in cell division, plays a crucial role in maintaining the integrity of the centrosome, a tiny organ essential for organizing chromosomes during cell division. This breakthrough understanding could lead to new strategies for designing cancer treatments.