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Northwestern University


Building trustworthy big data algorithms

A new algorithm, TopicMapping, has been developed to improve the accuracy and reproducibility of big data text analysis. By using a network approach, the algorithm separates unstructured text into topics with high accuracy and reproducibility. The results show that existing algorithms, such as LDA, are not reliable for complex datasets.

SourceNorthwestern University·JournalPhysical Review X·DateJan 29, 2015

Why upper motor neurons degenerate in ALS

Researchers at Northwestern University have discovered that increased stress in the endoplasmic reticulum is a key factor in the degeneration of upper motor neurons in ALS. This finding could lead to the development of new therapies aimed at improving the survival of these critical cells.

SourceNorthwestern University·JournalCerebral Cortex·DateJan 28, 2015

'Friending' your way thin

A Northwestern University study found that online dieters who logged in regularly, recorded their weigh-ins, and 'friended' other members lost an average of 8% of their body weight over six months. In contrast, those with fewer interactions lost only about 5% of their body weight.

SourceNorthwestern University·JournalJournal of The Royal Society Interface·DateJan 28, 2015

Infrared imaging technique operates at high temperatures

Researchers at Northwestern University developed a new detector that can capture high-resolution mid-wavelength infrared images at room temperature, paving the way for applications in surveillance and disease detection. The technology has potential for vascular imaging and disease detection, particularly with images of the human body.

SourceNorthwestern University·JournalOptics Letters·DateJan 23, 2015

Family voices and stories speed coma recovery

A Northwestern University study found that family members sharing familiar stories with coma patients who wore headphones recovered consciousness faster and had improved outcomes. This 'familiar auditory sensory training' stimulated the brain's memory circuits, helping patients wake up more easily and respond to their environment.

SourceNorthwestern University·JournalNeurorehabilitation and Neural Repair·DateJan 22, 2015

Automated method beats critics in picking great movies

A Northwestern University study reveals an automated method of analyzing movie citations outperforms human critics and crowd wisdom in predicting a film's significance. The researchers analyzed over 15,000 movies and found that the number of references by other movies is the best predictor of inclusion in the National Film Registry.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateJan 19, 2015

Eczema woes not just skin deep

Adults with eczema are more likely to experience health problems such as diabetes, high blood pressure, and insomnia due to the emotional toll of the disease. Physicians need to address these lifestyle risks alongside skin treatments.

SourceNorthwestern University·JournalJournal of Allergy and Clinical Immunology·DateJan 15, 2015

Rihanna eases kids' pain after surgery

A Northwestern University study found that pediatric patients who listened to their chosen music or audiobooks had a significant reduction in post-surgical pain. The therapy was effective regardless of the patient's initial pain score and can be used as an alternative to opioid analgesics.

SourceNorthwestern University·JournalPediatric Surgery International·DateJan 8, 2015

Human speech's surprising influence on young infants

Researchers find that listening to human speech promotes infants' cognitive, social psychological capacities and has positive developmental consequences. Infants as young as 2-3 months old benefit from tuning in to speech, leading to better understanding of patterns, recognizing partners, and establishing coherent categories.

SourceNorthwestern University·JournalTrends in Cognitive Sciences·DateJan 5, 2015

Stunning zinc fireworks when egg meets sperm

A Northwestern University-led team uses cutting-edge technology to capture images of zinc sparks in egg cells, revealing a crucial role for zinc in regulating biochemical processes. The study's findings could improve in vitro fertilization methods by identifying high-quality fertilized eggs.

SourceNorthwestern University·JournalNature Chemistry·DateDec 15, 2014

Heavier newborns show academic edge in school

Research from Northwestern University found that heavier newborns have higher test scores from third through eighth grade. Even among twins, heavier-born twins have higher average test scores. However, other factors such as maternal education can be a larger predictor of academic achievement.

SourceNorthwestern University·JournalAmerican Economic Review·DateDec 2, 2014

New terahertz device could strengthen security

Researchers at Northwestern University developed a compact terahertz radiation source that operates at room temperature, offering improved security detection capabilities. The device has a wide frequency coverage and can detect explosives, chemical agents, and biological substances from safe distances.

SourceNorthwestern University·JournalApplied Physics Letters·DateNov 21, 2014

New process isolates promising material

Researchers at Northwestern University have developed a method to isolate atomically thin sheets of molybdenum disulfide (MoS2), a promising material for optoelectronics and electronics. The process uses copolymer-assisted gradient ultracentrifugation, allowing for scalable isolation of single-layer, bilayer, or trilayer MoS2 sheets.

SourceNorthwestern University·JournalNature Communications·DateNov 13, 2014

Safest cosmetic surgery procedures

A new Northwestern University study analyzed over 20,000 minimally invasive cosmetic procedures and found no risk of serious adverse events. The study suggests that these procedures are exceedingly safe, with fewer than 1% minor complications, offering a significant cosmetic boost through mixed procedures.

SourceNorthwestern University·JournalJAMA Dermatology·DateNov 5, 2014

Smoking is a pain in the back

A Northwestern University study found that smokers are three times more likely to develop chronic back pain and that quitting the habit may reduce vulnerability to this condition. The research also identified a key brain region involved in addictive behavior and motivated learning.

SourceNorthwestern University·JournalHuman Brain Mapping·DateNov 3, 2014

Even when you're older you need chaperones

Researchers found that the quality of protective molecular chaperones declines dramatically with age, accelerating decline in those with neurodegenerative diseases. A subnetwork of 28 critical genes provides a basis for biomarkers and new therapeutics to prevent protein damage and cell dysfunction.

SourceNorthwestern University·JournalCell Reports·DateNov 3, 2014

Accident prone eczema patients

Adults with eczema are more likely to experience accidental bone fractures and other injuries, according to a new Northwestern University study. The increased risk may be linked to the side effects of steroids and sedating antihistamines commonly prescribed for eczema.

SourceNorthwestern University·JournalJAMA Dermatology·DateOct 29, 2014

Head Start program benefits parents

A Northwestern University study found that Head Start programs benefit parents' educational status and employment, particularly among African-American parents and those with some college education. The program may provide a platform for expanding parents' own educational opportunities and improving their work-school-family balance.

SourceNorthwestern University·JournalJournal of Policy Analysis and Management·DateOct 20, 2014

Country's economy plays role in Internet file-sharing patterns

Researchers analyzed 10,000 BitTorrent users from around the world and found that most are 'content specialists' sharing specific types of content, such as music or movies. The study also reveals a correlation between country's GDP per capita and file-sharing behavior, with users in poorer countries downloading larger files like movies.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateOct 8, 2014

New absorber will lead to better biosensors

Researchers at Northwestern University have developed a new nanostructure that absorbs a very narrow spectrum of light, enhancing the sensitivity of biosensors. This ultranarrow band absorber can detect smaller changes in the environment and has been shown to exceed 90% absorption at visible frequencies.

SourceNorthwestern University·JournalACS Nano·DateOct 1, 2014

The cultural side of science communication

A new Northwestern University study highlights the importance of considering cultural differences in science communication, finding that media often reflects cultural orientations and assumptions. The research reveals that Native Americans tend to see themselves as part of nature, while European-Americans view humans as apart from it.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateSep 30, 2014

First mouse model for ALS dementia

Researchers at Northwestern University have created the first mouse model for ALS dementia, allowing scientists to directly view the brains of living mice under anesthesia. This breakthrough enables rapid testing and real-time monitoring of test drugs, paving the way for accelerated development of effective therapies.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateSep 24, 2014

We drink more alcohol on gym days

A Northwestern Medicine study found that people drink more alcohol on days when they exercise, particularly Thursdays to Sundays. The study used smartphone technology to record daily physical activity and alcohol use, and found uniform results across age groups.

SourceNorthwestern University·JournalHealth Psychology·DateSep 22, 2014

First blood test to diagnose depression in adults

A new blood test identifies 9 RNA markers tied to depression, predicting who will benefit from therapy and providing the first objective, scientific diagnosis. The test also shows biological effects of cognitive behavioral therapy, offering personalized medicine approach to people suffering from depression.

SourceNorthwestern University·JournalTranslational Psychiatry·DateSep 16, 2014

New glaucoma culprit is found

Researchers found that endothelial cells in eyes with glaucoma are stiffer than healthy cells, leading to increased flow resistance and elevated pressure. This mechanical dysfunction may lead to a cure for the debilitating disease.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateSep 12, 2014