Scientists have identified a crucial portion of a protein responsible for hereditary cerebral amyloid angiopathy (CAA), a disease linked to stroke and dementia. The study used solid-state nuclear magnetic resonance (NMR) spectroscopy to reveal the structure of CAA fibrils, which form plaques in blood vessels in the brain.
Researchers at Ohio State University have discovered that specific structural parts of a viroid are responsible for its multiplication and spread in plants. The study's findings could lead to the development of genetic alterations to prevent viroid infection, with potential applications in human virus research.
A survey by Ohio State University found that public opinion about outdoor cats varies widely across the state, with some residents supporting spay-neuter laws and others believing local governments should control free-roaming cats. The study suggests a community-based approach is needed to address the issue.
A new study from Ohio State University found that conjugated linoleic acid (CLA) may need to be paired with the hormone leptin to prevent side effects of rapid weight loss. The study used mice genetically engineered to have no leptin, finding that CLA diets can result in weight loss but also insulin resistance.
A recent study by Ohio State University researchers found that seniors who develop serious illnesses later in life lose more of their savings. The study compared the long-term financial repercussions of pre-existing chronic health problems with those caused by the sudden onset of a new health problem late in life. Participants over 70 ...
A six-year study found that urban areas attract lower-quality Acadian Flycatcher birds, which have reduced nesting success. These birds are more likely to fail or abandon their nests and return year after year.
Researchers found two star systems with yellow supergiant eclipsing binary characteristics, which may be the progenitors of rare supernovae. The discovery was made using the Large Binocular Telescope and suggests that these systems could explain the unusual nature of certain supernovae.
A review of 75 group-randomized cancer trials found that fewer than half used appropriate statistical methods to analyze results. The studies' flawed designs may have led to incorrect conclusions about intervention effectiveness.
Despite national guidelines for asthma treatment issued in 1997, many patients still do not receive prescription inhalers for the safest and most effective long-term control of the disease. Researchers found that elderly and minority patients were less likely to be prescribed long-acting controller medications.
Researchers at Ohio State University identified 14 types of mold on and around Madagascar hissing cockroaches, including molds associated with allergies. Handling the insects may trigger allergic responses in sensitive individuals if proper cleaning and care are not taken.
Researchers at Ohio State University are developing a technology to coat turbine blades with zirconium dioxide, also known as synthetic diamond, to combat high-temperature corrosion. The coating converts corrosive particles into a protective outer layer, renewing itself constantly.
A new study by Ohio State University researchers found that neighborhoods with higher levels of poverty, lower education, and more female-headed families tend to have lower exercise levels. Social and economic factors outside of individual control can impact physical activity.
Researchers at Ohio State University have identified a key gene, SUN, controlling the elongated shape of tomatoes. This discovery sheds light on the genetic basis of fruit shape variation in various crops, including peppers and cucumbers.
Scientists develop a new, lean mouse model by crossing mice deficient in protein kinase C beta (PKCB) with the C57 black mouse. The hybrid mice have less fat distribution, less fat tissue overall, and increased ability to burn fat, suggesting a potential strategy for treating obesity and disorders associated with excess weight.
Researchers have successfully treated mice with a gene responsible for making follistatin, a protein that inhibits myostatin, leading to long-term improvements in muscle mass and strength. The therapy has potential for older patients with Duchenne muscular dystrophy, who often lose treatment options once muscles degenerate.
Researchers found that healthy coral polyps rely on both photosynthetic carbon from algae and feeding-derived carbon for survival. The study suggests a key role for this dual carbon source in coral recovery from bleaching, with implications for the management of these critical ecosystems.
A survey of 305 college students found that 40% of cell phone users said they walked alone at night after dark. Women reported feeling safer with their phones, leading to increased willingness to take risks.
A study by Ohio State University found no improvement in immune status, wound healing, or pain control among participants exposed to aromatherapy oils. However, lemon oil showed a positive effect on moods, while lavender oil had no impact.
Research suggests that about one in four women with HIV expect pregnancy and motherhood, with younger women more likely to make this choice. The study highlights the need for clinicians to discuss pregnancy options with HIV-positive women of childbearing age.
Researchers at Ohio State University identified two proteins, MprF1 and MprF2, that contribute to bacterial resistance by altering the electrical charge of cell membranes. This finding could lead to the development of new drugs targeting bacterial resistance at its cellular source.
Thompson and Mosley-Thompson's work on ice cores provides comprehensive records of climate change over centuries, vital for forecasting future changes. Their efforts have garnered over 200 academic publications and led more than 60 expeditions to remote sites across five continents.
A long-term study found that middle-aged women who suffered physical or sexual abuse as children spent significantly more on healthcare costs. Women with an average age in their late 40s still suffer consequences from abuse that occurred decades ago.
New analysis suggests SARS originated in bats, not palm civet cats as previously thought. The study reveals humans were the source of the virus found in those animals, contrary to earlier findings.
An international team of astronomers has discovered two planets resembling smaller versions of Jupiter and Saturn in a solar system nearly 5,000 light years away. The newly-discovered planets appear to be gaseous planets with masses similar to those of the giant planets in our own solar system.
Research suggests that powerful individuals are less receptive to new ideas when they feel confident in their own opinions. Conversely, when made to feel powerless, they pay closer attention and weigh arguments more carefully. By temporarily reducing power, leaders can increase the likelihood of persuasion.
Research reveals that doctors are reluctant to prescribe sleep aids to patients with depression, anxiety, or mood disorders, except for psychiatrists. However, new guidelines are needed to address this knowledge gap and ensure patients receive appropriate treatment for their insomnia.
Researchers design a mathematical model to describe circumstances where generalists can endure and even thrive in what is typically expected to be a specialist-only society. The study's findings suggest that having individuals with diverse skills can safeguard against the possibility that specialists don't complement each other.
A study of 227 breast cancer patients found that those who participated in a psychological intervention program had better health and functioning scores, with a 7% increase compared to non-participants. The program included training on relaxation, coping with stress, and strategies for improving health behaviors, resulting in fewer sym...
A study of pharmacists reveals that drive-through windows lead to increased processing times, reduced efficiency, and dispensing errors. The survey found that automated dispensing systems can reduce errors and enhance efficiency by minimizing workflow interruptions.
Workers with extended work schedules face higher risks of losing their jobs after injury, according to Ohio State University research. Injured employees in nonstandard schedules are more likely to be fired or quit, emphasizing the importance of tailoring return-to-work plans to individual employees' schedules.
Researchers at Ohio State University identified a genetic link between the profilin 1 gene and increased risk of high blood pressure in older adults. The gene affects vascular remodeling, which can lead to structural and functional changes in blood vessels, ultimately causing hypertension.
Astronomers have discovered a rare type of star system containing a black hole that suddenly began glowing brightly with X-rays. The system, dubbed CXOU J132518.2-430304, is thought to be a binary star system where one star collapsed to form a black hole.
A new study reveals that approximately 10% of EMTs and paramedics in the US miss work because of job-related injuries and illnesses. The study found that responding to high call volumes, working in urban areas, and having a history of back problems increase the risk of injury.
Researchers at Ohio State University Medical Center found that serotonin and synthetic hallucinogens trigger different chemical pathways in brain cells, leading to important implications for drug development. The study's findings suggest that screening agents must also determine if the agent signals through beta-arrestin.
Researchers developed a novel approach to gauge disease progress in adult T-cell lymphoma and leukemia, using firefly genes to detect cancer cells. The study found that combining PS-341 and zoledronic acid effectively killed 95% of ATLL cells, while also reducing bone resorption and calcium buildup.
Researchers found that vacuuming is an effective way to kill fleas, with a high success rate in killing adult fleas (96%) and destroying younger stages (100%). The study suggests that the physical abuse caused by the vacuum's brushes and fans leads to flea death.
A new study suggests that urban sprawl has continued to grow significantly in the US over the past few decades, particularly in exurban areas. The research found significant increases in fragmentation of land use patterns, with housing development juxtaposed with agricultural or forested areas.
Scientists have discovered giant mud waves in the Arctic Ocean, measuring nearly 100 feet across, defying previous expectations of calm ocean currents. The expedition aims to understand how water is exchanged between basins and how the Arctic affects global climate systems.
Scientists found a potential reason for Greenland's ice melting: a thin spot in the Earth's crust enabling underground magma to heat the ice. The researchers believe this hotspot could be lubricating the base of the ice sheet, causing it to slide more rapidly out to sea.
New software helps NASA's Spirit rover find a safe winter haven on Mars, called Von Braun. However, the path to get there is too treacherous, with no suitable bail out spots along the route. The software uses satellite images and rover images to map features on the surface.
Researchers found missing radioactive signals in Tibetan ice cores, indicating the Himalayan glacier has shrunk at least since the A-bomb test half a century ago. The loss of freshwater from glaciers could impact nearly half a billion people in India.
Researchers found that Bush supporters expressed less interest in viewing images, but this effect was reduced when they weren't first told about the policy. In contrast, non-Bush supporters showed more interest regardless of whether or not they were informed.
A $4.5 million POLENET project aims to cover West Antarctica with GPS trackers and seismic sensors, enabling systems-scale science through the dark polar night. The network will record data from 2010 to 2012, providing insights into climate change's impact on the WAIS.
A new study reveals microRNAs can directly control a protein's function, preventing immature blood cells from maturing and contributing to the development of blast-crisis CML. Altering microRNA levels may represent a potential therapeutic strategy for CML patients who don't respond to targeted agents.
Researchers compare images of Mars gullies to McMurdo Dry Valleys' saltwater flows, finding similarities that suggest liquid water on Mars. The study bolsters the notion of microbial life on Mars, as bacteria thrive in the Antarctic landscape's similar conditions.
Researchers found that Greenland's glaciers responded similarly to the 1920s warming event, with the Kangerdlugssuaq Glacier losing nearly a mile of ice in 1932. This parallels recent changes, increasing alarm about the island's ice fields and sea level rise.
Scientists have identified genetic differences that predict the effectiveness of antipsychotic drugs for patients with schizophrenia, Parkinson's disease, and drug addiction. These markers may enable doctors to match patients with the most suitable therapy, improving treatment outcomes.
Researchers found that blocking blood vessel growth with an antiangiogenic agent can reduce inflammation and improve antitumor efficacy of oncolytic virus therapy. This approach may increase survival rates for patients with aggressive brain tumors.
Researchers at Ohio State University have found that stress hormone norepinephrine promotes tumor cell growth and metastasis in certain types of blood cancer. The study suggests that blocking norepinephrine receptors may slow disease progression and improve treatment outcomes.
Researchers directly observed how water molecules link with proteins, enabling movement and function. The study challenges conventional wisdom and provides new insights into protein-water interactions.