Researchers at Ohio State University Medical Center found that the mitochondria send a death signal to cardiac cells when blood flow is restored, leading to cell damage and weakening heart function. The study identifies a specific enzyme, mitochondrial nitric oxide synthase, as a potential therapeutic target to stop this process.
A new study from Ohio State University suggests that climate change could diminish drinking water resources by up to 50 percent more than previously thought. As sea levels rise, coastal communities may lose fresh water supplies, with vulnerable areas including Southeast Asia, the Middle East, and northern Europe.
Researchers at Ohio State University found evidence that the Earth's atmosphere may have supported an oxygen-rich environment half a billion years ago. This oxygen surge could have triggered a rapid diversification of life on Earth during the late Cambrian period.
Researchers at Ohio State University developed software to enable remote operation of high-powered instruments like microscopes and telescopes. The software, RICE, utilizes economic principles to optimize network bandwidth, preventing mistakes and reducing frustration.
The project aims to reveal how some viral infections become resistant to antiviral medications. Researchers will test the interactions between FIV, a cat virus, and an AIDS drug called AZT in the presence of methamphetamine.
Researchers at Ohio State University found that summer nighttime low temperatures in Ohio have risen by about 1.7 degrees Celsius (about 3 degrees Fahrenheit) since the 1960s, mainly due to increased humidity and cloud cover. This warming trend is expected to affect the state's climate, with a typical summer night being 20 degrees Fahr...
Researchers found a link between depression, latent viral infections, and increased inflammation, which may contribute to the development of cardiovascular disease. The study suggests that chronic depression can trigger a cascade of events that lead to the buildup of plaques in coronary arteries.
Researchers found that chronic caregivers develop genetic and molecular changes that effectively age their bodies by four to eight years, resulting in a shortened lifespan. Caregivers also exhibit severe depression symptoms and weakened immune systems, contributing to the negative effects of chronic stress.
Research reveals that Hispanic adolescents are less affected by parental divorce, but this is not due to a lack of resilience; instead, they start with more challenges. In contrast, European and Asian American teens face significant problems after family disruption, while African Americans show fewer issues before the breakup.
Researchers at Ohio State University have identified a molecule that can reverse damage and help restore blood flow to vessels constricted during a heart attack. The treatment involves delivering tetrahydrobiopterin directly to the vessels, which can improve outcomes for patients with acute coronary episodes.
A new study by Ohio State University Medical Center found that nearly 40% of varsity athletes tested positive for exercise-induced asthma, including those without a prior history of the condition. The study highlights the need for routine diagnosis and management tools to detect this potentially serious condition among athletes.
Researchers at Ohio State University found that extracts from Hass avocados kill or stop the growth of pre-cancerous cells leading to oral cancer. The study highlights the potential health benefits of consuming phytonutrient-rich foods like avocados.
Researchers found that an important melanoma treatment has little effect on cancer cells themselves, but instead boosts immune system cells. The study highlights the need to develop ways to make melanoma cells more vulnerable to the drug or overcome the block within cells that prevents them from responding.
Researchers discovered that an experimental multiple sclerosis drug, fingolimod, may also help patients with certain lethal forms of leukemia. The study found that the drug prevents cancer cell development and kills leukemia cells in mouse models, suggesting a promising new approach for treating resistant cases.
Researchers found that light trucks, including SUVs and minivans, produced 0.5-0.6% more toxic air pollutants than conventional cars in a downtown Baltimore parking garage. The study provides new insights into the health risks of vehicle-related air pollution in urban settings.
Researchers at Ohio State University are developing a new technology to keep artificial liver cells alive and functioning normally. By creating different types of hemoglobin-based oxygen carriers, they can recreate natural oxygen gradients, allowing the liver cells to function as well as they do in the body.
Researchers at Ohio State University have developed a new microbial fuel cell that harnesses the power of cow waste to generate electricity. The small cell can produce about three times the power as its predecessor and is a quarter of its size, making it a promising alternative energy source.
A recent study found that diabetics who use insulin pens have significantly lower healthcare costs compared to those who use syringes. The annual average healthcare costs were nearly $17,000 lower for pen users than for syringe users, resulting in substantial savings to diabetics and their insurers.
Researchers warn of the growing prevalence of ineffective and potentially dangerous fad treatments for autism. Despite limited scientific evidence, parents are often willing to try various therapies in hopes of finding relief for their child.
Researchers found that anthocyanins from purple corn, chokeberries, and bilberries can slow the growth of colon cancer cells. The compounds were tested on human colon cancer cells and rats with colon cancer, showing promising results. Further studies are needed to understand how these compounds interact with other food components.
A researcher at Ohio State University suggests that ingroup bias doesn't require conflict with other groups, but rather a desire for trust and security within one's own group. This is contrary to the common misconception that people join groups to boost their self-esteem or to assert dominance over others.
A study by Ohio State University sociologist Paul von Hippel found that students in year-round schools showed similar improvement in math and reading test scores compared to traditional nine-month schools. While disadvantaged children may gain slightly more in reading, the overall impact on academics is minimal.
Researchers found that women with social physique anxiety who took an exercise class focusing on health benefits enjoyed the workout and reported improved attitudes towards future participation. In contrast, those taught by instructors emphasizing appearance reported lower enjoyment and engagement.
Research reveals how microRNA miR-21 helps cancer develop by blocking tumor-suppressor gene PTEN. High levels of miR-21 are found in many kinds of cancer cells, providing a potential marker for patient prognosis.
A new study suggests that acute leukemia patients with a specific genetic mutation may benefit from aggressive therapy to extend their disease-free survival. Researchers found that treating patients with the MLL-PTD mutation with an autologous stem cell transplant significantly reduced early relapses.
A new study found that African Americans on death row for killing non-whites are less likely to be executed than other condemned prisoners. Blacks who kill whites face a higher risk of execution, with a disparity in execution rates based on the race of victims.
Researchers at Ohio State University have developed new pink dye-sensitized solar cells with half the efficiency of commercially available silicon-based solar cells, but at one quarter of the cost. The new materials use complex metals and novel particle shapes to boost electricity production.
Researchers used powerful imaging techniques to study the atomic level interactions between bacteria and antibiotics, revealing a key enzyme structure that enables gene expression. The findings provide insights into potential new antibiotic designs that can prevent bacterial resistance.
A new study reveals a significant increase in creeping vines in southeastern US forests, with up to a 10-fold growth in just two decades. The vines' adhesive roots and tendrils are changing the forest's makeup, leading to a decrease in small tree density.
A study found that adults in high-crime neighborhoods avoid intervening with young offenders due to fear of retaliation. Adults are more likely to intervene when outsiders are involved or when they have a personal relationship with the youth.
A new study by Ohio State University researchers links high ERG gene activity to a more lethal subtype of acute myeloid leukemia (AML). Patients with high ERG expression are almost six times more likely to relapse or die within five years, highlighting the need for more intense therapy.
Researchers at Ohio State University have developed software that enables smart traffic boxes to detect road incidents more efficiently, reducing communication costs by up to 90% and achieving accuracy rates of over 90%. This innovation aims to help transportation authorities identify incidents more effectively, thereby reducing conges...
A recent study suggests that people with high cholesterol levels may be more susceptible to severe cases of tick-borne disease. The study found that bacteria levels were 10 times greater in mice with high cholesterol, indicating a potential link between cholesterol and disease severity.
A new type of engineered drug candidate has shown promise in treating chronic lymphocytic leukemia by targeting the CD37 protein on leukemia cells and triggering self-destruction. The agent works equally as well as rituximab, a commonly used treatment for CLL.
Researchers at Ohio State University developed a new technology using nano-fibers that can conduct electricity and repel dirt. These fibers have diverse applications in self-cleaning surfaces, transparent electronics, and biomedical tools, including manipulating DNA strands.
A study by Ohio State University found that most white Americans believe living as a black person would cost less than $10,000, but would need $1 million to give up television. This suggests a lack of understanding about persistent racial disparities in the US, including lower income and wealth for blacks.
A new study identified a genetic mutation in the DAPK1 gene that increases the risk of chronic lymphocytic leukemia. The mutation reduces the gene's protective activity and can be followed by a chemical change called DNA methylation, which leads to leukemia.
Researchers found that modifying irrigation and waste treatment practices, along with providing medicine and pesticide, can reduce the spread of schistosomiasis. These changes include lining irrigation ditches with concrete to eliminate snail habitats and using biogas digesters to destroy Schistosoma eggs.
Researchers discovered nearly a dozen additional heat-shock proteins that help insects survive cold temperatures. These proteins are essential for insect survival during diapause, a hibernation-like state that allows them to withstand low temperatures.
Researchers employed a new technique to estimate dark matter location and calculate its mass, shedding light on the galactic halo's composition. The method revealed two massive dark objects, one with 7 times the sun's mass, in the Milky Way's outer reaches.
Lonnie Thompson, a renowned glaciologist, will receive the National Medal of Science for his groundbreaking research on global climate change. His team has provided irrefutable evidence that the last half-century was the warmest period in recorded history.
A study published in the Proceedings of the National Academy of Sciences found that tropical birds expend less energy at rest compared to northern bird species. The researchers measured basal metabolic rate (BMR) and peak metabolic rate (PMR) in 69 species of tropical birds, finding they used about 18% less energy than temperate birds.
A new study at Ohio State University found that estrogens increase aggression in mice during short days and decrease it during long days. The researchers identified the mechanisms underlying this interaction, revealing a genomic pathway for estrogen's effects in long-day mice and a different cellular mechanism for short-day mice.
Scientists found a new species of sea anemone, Anthosactis pearseae, living on the carcass of a dead whale 1.8 miles below sea level. The anemone is small and white, with roughly uniform tentacle length, and may provide clues about human impact on deep-sea ecosystems.
Researchers at Ohio State University Comprehensive Cancer Center have discovered a way to distinguish pancreatic cancer from non-cancerous tissue using microRNA molecules. The study found that specific miRNAs can predict patient survival rates, with correlations seen in just a few miRNAs that were not previously associated with the dis...
Researchers created a supermap of the H5N1 virus using genetic, geographic, and evolutionary data to predict future outbreaks. The map revealed no significant association between mutations in surface proteins HA and NA and specific host types.
A study of nearly 600 people with hay fever symptoms found that workers missed an average of one hour of work per week during peak seasons. Diagnostic testing followed by proper treatment may help reduce missed work days.
A nationwide study by Ohio State University's Jay Zagorsky found that people with below-average intelligence are just as wealthy as those with higher IQ scores. However, high-IQ individuals tend to earn higher incomes but struggle with financial difficulties such as maxed-out credit cards and missed bill payments.
A new study suggests that targeting the survival protein Mcl1 may be an effective way to treat leukemia, particularly when combined with existing drugs like rituximab. The research found that knocking out Mcl1 can cause cancer cells to die, and combining it with rituximab killed significantly more leukemia cells than the drug alone.
A new study from Ohio State University found that couples with a strong marital relationship tend to handle temperamental babies better than those without. The study, which involved 97 couples, showed that poor coparenting relationships can have long-term effects on children's behavior.