Researchers developed a bioinspired Janus air electrode with a fish-scale and waterspider-leg structure, enabling rapid substance transport and improving catalytic site utilization. The asymmetric architecture significantly enhances zinc-air battery performance, achieving high power density and specific capacity.
Researchers developed a light-responsive nanoassembly that enables precise and controllable drug delivery inside tumor cells. The strategy achieves strong tumor suppression while effectively inhibiting tumor spread, without causing noticeable systemic toxicity.
A new study finds periphyton, a thin microbial community at the soil-water interface, captures 6-24% of applied fertilizer N. Periphyton stores approximately 0.8 teragrams of nitrogen annually, closing the paddy-field nitrogen budget gap.
Researchers developed a novel phosphorus-carbon-bridged cyclization strategy, yielding high-performance blue emitters with exceptional color purity and electroluminescence efficiency. The synergistic heavy-atom effect of phosphorus and sulfur significantly enhances reverse intersystem crossing rates, leading to ultra-high efficiency an...
A comprehensive review argues that single-factor interventions in Alzheimer's disease are insufficient due to the complex interplay of multiple factors. The authors call for an integrated therapeutic approach, including multi-target therapies and precision medicine based on early biomarkers.
Developing high-performance Ni-rich cathode materials is crucial for achieving single-cell energy densities exceeding 400 Wh kg‑. A research team synthesized quinary full-concentration-gradient cathodes using an in-situ co-precipitation strategy, featuring a Mn-rich, Ni-poor surface and radially aligned primary particles.
Researchers found that microbes can use mercury sulfide nanominerals as an energy source, releasing volatile elemental mercury into the air. The study estimates that this process could release hundreds of tons of mercury per year, comparable to cement production.
Researchers found that widespread flooding in the Middle Yangtze Valley led to the decline of the Shijiahe culture around 4,200 years ago. The study used stalagmite analysis to reconstruct rainfall patterns and show that high-rainfall intervals were associated with increased flooding and a significant decline in population.
An international team uncovered a 7,700-year-old 'north-south corridor' of human interaction between Early Neolithic populations in Siberia and northern China. Genetic analysis revealed a distinct genetic signature linked to Lake Baikal populations, challenging previous views on trans-Eurasian contact.
A novel, self-regenerating 'bacteria-mineral' biohybrid system was developed to utilize light like a solar cell for uranium pollution purification. The system enhances the purification efficiency of uranium pollution through the use of metabolic activity of bacteria to grow ferrous sulfide nanoparticles.
Researchers identified OsMADS18 as a key regulator of grain chalkiness, enhancing the trait with loss-of-function mutations. OsbZIP60 was found to interact with OsMADS18, positively regulating chalkiness-related genes. The OsMADS18-OsbZIP60 module also influences grain weight and starch content under high-temperature conditions.
Researchers explore piezoelectric electrospun fibers that generate crucial electrical signals for tissue engineering and biomedical applications. These "smart" scaffolds have high flexibility, biomimetic structure, and tunable morphology, offering potential for enhanced tissue repair.
The development of spatial transcriptomics has advanced gene expression understanding, but selecting suitable analytical approaches is challenging. A database curated SpatialToolDB addresses this by classifying over 600 ST analytical tools and providing access to processed datasets.
A new rice gene, GSN7, has been discovered that can simultaneously increase grain yield and improve quality. The study found that precise manipulation of this gene can overcome the long-standing trade-off between yield and quality in rice breeding.
Researchers review schizophrenia mechanisms, including neurotransmitter dysregulation and immune dysfunction, to develop next-generation therapies. Promising treatments include TAAR1 agonists, muscarinic modulators, NMDA receptor enhancers, and probiotics targeting the gut-brain axis.
A novel multi-agent AI framework, eNRRCrew, has been developed to accelerate the discovery of sustainable catalysts for green ammonia synthesis. By analyzing a comprehensive database of scientific papers, the framework predicts a catalyst's performance and provides rational design principles.
A study reveals how a dual modification on histone H3.3 recruits silencing complexes to establish heterochromatin, crucial for gene silencing and X-chromosome inactivation. The 'H3.3-CBX7-KAP1' pathway is essential for building the repressive heterochromatin mark H3K9me3.
Quantized soliton pumping is observed in high-dimensional topological systems, governed by distinct-order Chern invariants. The study reveals integer- and fractional-quantized pumping behaviors and trapped regimes at strong nonlinearity.
Scientists at Shanxi University successfully demonstrate controllable deterministic continuous-variable quantum teleportation of up to 5 sideband qumodes simultaneously within a 24 MHz frequency bandwidth. The number of teleported qumodes can be controlled by adjusting the phases of classical channels, with fidelity above 70% achieved.
Researchers have developed a compact high-temperature superconducting magnetoplasmadynamic thruster, reducing power consumption by 96% and weight by 73%, enabling more efficient space propulsion. The thruster achieved an ultra-high specific impulse of 3,265 seconds, significantly reducing spacecraft fuel requirements and launch costs.
A study analyzing outcomes from 795 patients with severe aplastic anemia found that donor age significantly impacted long-term survival and graft success. Younger donors experienced consistently better outcomes, while older donors were associated with worse results.
Researchers investigate fractional quantum Hall effect in twisted MoTe2, revealing spontaneous ferromagnetic transitions and exotic correlated phases. The study identifies characteristic spectroscopic signatures of these phases, providing a unified framework for interpreting existing measurements.
A study reveals disulfiram inhibits tumor growth in liver cancer by modifying RNA and activating c-FOS, which suppresses lipid metabolism and angiogenesis. High expression of TRMT10C and PCSK9 is associated with poor prognosis, while high c-FOS is linked to better survival.
Researchers developed a supramolecular photocatalyst with hydrogen bonds that enhance exciton dissociation and charge migration, leading to improved oxygen evolution rates. The system boosts internal electric fields, driving faster charge migration and increased holes on the catalyst surface.
A new theory suggests that water accumulated in the mantle caused an overturn, supplying materials for continent formation and strengthening the geodynamo. This event accelerated core cooling, correlating with high paleointensities in Archean rocks.
A recent study questions AI model Centaur's ability to simulate human cognition, suggesting it relies on statistical patterns rather than genuine understanding.
A new study proposes a two-component self-interacting dark matter model that naturally reproduces observational results for dwarf galaxies and strong gravitational lensing. The model predicts mass segregation, where heavier particles sink towards galaxy centers and lighter particles diffuse outward.
Researchers control light emission from individual molecules, enabling future technologies like quantum computing and ultra-dense displays. The team's roadmap includes achieving stable, room-temperature single-photon emission by 2026 and integrating multiple devices for small-scale quantum information processing.
A team from Donghua University has developed a new molecular design that improves the performance of photothermally healable elastomers. The resulting material, PIB5Cu, achieves all-round upgrades in toughness, tensile strength, photothermal conversion efficiency and healing efficiency.
New diagnostic methods aim to detect RNA viruses with high sensitivity and specificity, overcoming the challenge of rapid evolutionary dynamics. The techniques include mutation-tolerant screening and precise mutation discrimination.
Researchers achieved hybrid spin-orbit coupling-driven optical spin Hall effect in organic microcavities, offering a new approach for polarization-preserving components and spin-photonic functionality. The system provides more than one 'topological' spin texture within a single device, accessible by adjusting momentum.
Protein Foundation Models (pFMs) leverage vast amounts of sequence and structural data to predict protein structures and functions, enabling novel protein design and analysis. The models have evolved into several mature technical approaches, demonstrating versatility in basic biological research, protein discovery, and biomedical appli...
Researchers have developed a new approach to improve rice's resistance to pathogens by combining basal immunity with effector-triggered immunity. The hybrid rice plants show full resistance to certain strains and improved resistance to others, while alleviating growth defects.
A new low-crosstalk iontronic e-skin design suppresses mechanical strain propagation while maintaining sensitivity, enabling stable and reliable multi-point spatial perception. This system achieves efficient Braille recognition with auditory feedback, providing a promising technological pathway for assistive tactile sensing applications.
A new AI model, ShapKAN, has been integrated into the cloud-based platform AI4Min-PE to predict five critical thermodynamic parameters across extreme pressures. The platform offers speed and accuracy far beyond conventional approaches, enabling scientists to explore the chemistry of materials under extreme conditions.
Researchers discovered a probiotic strain, Bifidobacterium animalis subsp. lactis B960, that enhances the glucose-lowering effects of glibenclamide with minimal degradation. This combination therapy reduces fasting blood glucose levels and improves pancreatic function while alleviating hepatotoxicity.
Researchers developed a new approach to teach robots to learn human grasping skills, enabling adaptive and universal grasping to diverse objects. The framework captures multimodal tactile data and encodes it into high-level semantic grasping states, allowing robots to recognize general states of interaction.
A research team developed a zero-dimensional hybrid metal halide that exhibits reversible fluorescence switching under pressure and solvent stimulation. The material can be toggled between non-emissive and highly emissive states, paving the way for multifunctional optical applications.
Researchers discovered a new route to quantum criticality in a material with atomic disorder, where a weak magnetic field triggers a transition from spin clusters to a coherent heavy-electron metal. This finding expands the landscape for quantum materials research and provides insight into strange-metal behavior.
Researchers discovered a 'genome size–ecological function' differentiation pattern among cyanobacteria, identifying smaller genomes as 'streamlined types' that dominate in phosphorus-deficient environments and rarely produce toxins. This study proposes using a genome size threshold to initiate preventive measures before blooms occur.
Scientists have developed injectable nanorobots with ultrasensitive chemotaxis for precision cancer therapy, achieving high targeting efficiency, deep penetration, and significant cell internalization in a tumor-bearing mouse model. The nanorobots showed a 49-fold boost in tumor suppression efficacy compared to passive counterparts.
A new study suggests that current climate actions may not effectively curb global warming acceleration, as aerosol reduction weakens cooling effect. Climate policy assessments need to consider additional climate effects from co-reduced aerosols and their risks.
A team of researchers developed an AI algorithm capable of classifying complex topological phases of matter without relying on traditional mathematical tools. The breakthrough tackles the notoriously difficult realm of non-Hermitian systems and suggests that AI can surpass human capabilities in certain domains of abstract reasoning.
A novel photodynamic platform combines antibacterial action, hemostasis and pain relief under natural sunlight, enabling painless, antibiotic-free therapy for infected diabetic wounds. The treatment demonstrates rapid hemostatic capability and a pronounced analgesic effect.
Scientists discovered a novel method to identify upper-layer ozone intrusion events, which substantially elevate surface ozone levels and intensify atmospheric oxidation capacity. ULOI events accelerate wintertime sulfate and secondary organic aerosol formation in the North China Plain.
A comprehensive study reveals that urbanization significantly amplifies lake warming, threatening freshwater ecosystems. The research highlights the role of urban heat island effect and altered hydrological processes in driving accelerated warming.
A recent study reveals that over 680,000 new cases of hepatocellular carcinoma were estimated worldwide in 2022, with 78.4% attributable to nine modifiable risk factors. The majority of HCC cases are preventable, and the study emphasizes the need for targeted preventive programs.
Researchers have introduced a spatial-adaptive active-learning workflow to accelerate search for highly durable OER catalysts. The new method optimizes two objectives sequentially within a unified framework, identifying a Cu-RuO2 catalyst with exceptional performance and long-term stability.
Knocking out the OsDT5 gene boosts drought resistance in rice, corn, and wheat, as well as the bryophyte Physcomitrium patens. The study provides a unified mechanistic framework for drought adaptation in terrestrial plants.
A novel approach to designing crystalline organic nanofiber photosensitizers has been developed. These materials exhibit exceptional light harvesting and singlet oxygen generation capabilities, enabling rapid photooxidation of organic substrates.