A new unified mathematical description model for coastal tipping points has been introduced, addressing escalating risks in coastal zones. The model classifies tipping points into six types, including bifurcation-driven, noise-driven, and shock-driven, highlighting the need for integrated strategies to mitigate regime shifts.
Scientists have discovered that Earth's inner core exists in a superionic state, where light elements flow through a solid iron lattice, dramatically softening it. This discovery redefines our understanding of the planet's deepest interior and offers new perspectives on seismic anisotropy and Earth's magnetic field.
The study found that the SAA proton flux center has been drifting westward and northward over five years, with lower-energy protons responding faster to geomagnetic inhomogeneity. The CSES satellite data also showed a significant decrease in the area of the SAA proton flux between 2019 and 2024, correlated with solar activity.
Researchers have discovered that certain seawater ions can be intentionally utilized to enhance electrochemical performance, rather than hindering it. This involves carefully designing catalysts and electrolytes to mitigate the negative effects of these ions while maximizing their benefits.
LD-110, a potent LSD1 PROTAC degrader, induces ER stress and apoptosis in cancer cells by degrading LSD1 and increasing H3K4me2 levels. This study reports the discovery of LD-110 as a highly effective therapeutic agent with potential synergistic effects when combined with GSPT1 degraders.
A team of researchers from Fudan University developed an ultrafast non-volatile memory using a 2D van der Waals heterostructure and metal-nanocrystal storage layer. The device achieves a large memory window, sharp interfaces, and significant endurance, making it suitable for high-speed and robust memory applications.
Researchers successfully established an Hmgn3-overexpressing embryonic stem cell line that exhibits advanced cellular plasticity and can differentiate into extraembryonic tissues. Overexpression of Hmgn3 enables these cells to stably contribute to the fetus, placenta, and yolk sac in vivo.
A recent study found that Mongolia has become a major source of dust emissions in Central East Asia, with total emissions increasing sevenfold from 2020 to 2023. The study attributes this shift to stronger surface winds, vegetation degradation, and reduced soil moisture.
Researchers propose a closed-loop system combining peripheral nerve stimulation (PNS) with brain-computer interfaces (BCIs) to personalize neuromodulation. This approach aims to address treatment-resistant depression and schizophrenia by dynamically tailoring interventions to individual neural signatures.
Researchers discovered that more symmetric states can restore symmetry faster than less symmetric ones in MBL systems, exhibiting the quantum Mpemba effect. This phenomenon occurs even without thermalization, shedding light on universal principles of nonequilibrium dynamics.
ADCs use targeted antibodies to deliver cytotoxic payloads directly into cancer cells, destroying tumors while minimizing harm to healthy cells. Two ADCs have been approved by the FDA for gynecological cancer treatment, and numerous others are in clinical trials.
Researchers have discovered a new polar order in a hybrid crystal, ferrielectricity, which enables electric control of spin-orbit coupling and circular photogalvanic effect. The material's switchable net polarization, asynchronous switching, and field-driven polar-to-polar transition demonstrate its unique properties.
Researchers propose a multi-pronged strategy to boost grain number in wheat by unlocking branched varieties, maintaining meristem activity, improving floret fertility, and enhancing nutrient transport. A multi-omics approach integrating genomics, metabolomics, and phenomics will be used to re-engineer wheat inflorescence architecture a...
Researchers have designed a new oligomer-based organic photodetector that achieves efficient SWIR (Short-Wavelength Infrared) photoresponse. The device features a thiophene-fused BODIPY tetramer with meta-dicyanophenyl end groups, enabling J-aggregation and cooperative molecular packing behavior.
Researchers designed a SPAN||Gr battery system with an optimized N/P ratio, achieving increased energy density. The anion-mediated electrolyte LH enabled stable electrochemical kinetics and improved cycle life. Lithium deposition on graphite showed a compact and smooth morphology in the LH system.
Researchers developed a universal texture-controlled approach for scalable fabrication of large-scale single-crystal metal foils. The method involves three stages: tailored cold rolling, controlled low-temperature recrystallization, and high-temperature annealing.
A research team led by Professor Shushi Peng has estimated global biological nitrogen fixation for natural land ecosystems, revealing substantial biases in widely used Earth System Models. The team found that the models underestimate natural terrestrial nitrogen fixation by up to 18%, with a multi-model mean of ~67.7 Tg N yr-1.
Researchers developed a biocatalytic platform using CYP152 peroxygenases for efficient α-hydroxylation of aromatic carboxylic acids, achieving high enantiomeric excess values and isolated yields above 92%. This green alternative offers a sustainable solution for the cost-effective production of enantiopure hydroxy acids.
The first 2D semiconductor FPGA has successfully integrated approximately 4,000 transistors on a wafer scale, marking a significant transition for 2D electronics. The device utilizes an independently innovated integration process platform to overcome critical challenges and achieve reliable operation.
Researchers studied mechanical properties of solids as a function of grain size and boundary thickness, revealing that thick boundaries improve strength and ductility in single-component face-centered cubic materials. However, for other materials, increasing boundary thickness softens the material due to dislocation-dominated plasticity.
Researchers designed a self-powered, compact tactile interface using an MXene/Bi 2D heterojunction. The device combines sensing, encoding, and low-power readout, achieving high sensitivity, fast response, and durability.
A new gradient anode design addresses key challenges in sodium batteries, achieving high-energy-density and stable performance. The symmetric cell demonstrates ultralong cycle life and unprecedented energy density of 200 Wh kg-1.
A new study found that failing to degrade maternal mRNAs triggers genomic traffic jams in mouse embryos, halting development at the first step. The research team discovered that increased chromatin accessibility and abnormal transcription regulation lead to R-loop formation, causing replication stress and DNA damage.
A new study finds that rare and common genetic variants counterbalance each other to maintain telomere stability. The researchers used data from 379,764 participants and found a compensatory genetic mechanism that prevents extreme shortening or lengthening of telomeres.
A swarm of miniature magnetic soft robots, inspired by fish schools, can coordinate their movements to deliver targeted drug therapy to diseased tissue. The robots can navigate through narrow passages and adapt their shape to conform to the lesion's boundaries for optimal drug delivery coverage.
The study reveals that North America and Europe will experience significant warming (3.7-3.8°C) and drought expansion by the end of the 21st century due to land-air coupling, which amplifies the impact of GHG emissions. If uncontrolled, this could lead to severe climate risks, including reduced Gross Primary Productivity.
A Chinese research team developed an innovative device that skips CO₂ purification, cuts costs, and produces commercial-grade HCOOH directly from dilute emissions. The membrane-integrated electrolyzer concentrates CO2 to high levels for efficient conversion, producing a valuable liquid fuel and industrial chemical.
Researchers have designed a new catalyst that stabilizes oxidized copper species under reducing potentials, enabling highly efficient and stable CO2 conversion to C2+ products. The cerium oxide nano-islands act as nanoscale anchors, preserving the active copper oxidation states.
Researchers from China have developed a bistatic dual-comb ranging approach that achieves nanometer-level absolute distance measurement over 113 kilometers, surpassing previous limitations. This technology provides breakthrough technical support for large-scale space research programs.
The SQUIRE project deploys quantum spin sensors on the China Space Station to search for pseudomagnetic fields induced by exotic interactions. These interactions can induce energy shifts in atomic energy levels, which can be detected as pseudomagnetic fields by quantum spin sensors.
Microbial metabolites from the gut microbiome influence gene expression, cellular function, and host health. The MDME axis proposes a unified theoretical framework explaining this complex dialogue.
A glassy metal-organic framework coating accelerates ion desolvation, stripping solvent molecules from lithium ions, while a second layer enables rapid transport into the graphite bulk. This synergistic design results in unprecedented fast-charging performance, with batteries maintaining high capacity and stability.
A recent study analyzed data from 4,348 pediatric patients with congenital heart disease to identify key predictors of prolonged ICU stays. The research highlights the importance of patient-specific and post-operative management factors in reducing extended care.
Researchers developed a universal texture-controlled approach for large-scale single-crystal metal foil fabrication, overcoming structural heterogeneity and process controllability issues. The method, demonstrated across multiple Cu precursor systems, produces foils with high-index orientations and exceptional performance.
A research group has constructed a 'material network' for metallic glasses, revealing that fully connected groups of elements are excellent predictors for new alloys. The study also found that many recent discoveries were already encoded in the network structure from earlier data.
A recent study published in Science Bulletin has provided direct evidence for herbivory in pterosaurs, resolving a long-standing debate. Researchers discovered phytoliths and gastroliths in the stomach of Sinopterus, confirming its plant-based diet.
Researchers developed a new Ru nanoparticle catalyst with enhanced light-harvesting capability, spectral response, and microscopic temperature fields, facilitating efficient CO2 methanation. The plasmonic coupling-confined architecture integrates electromagnetic field confinement and nanoscale thermal management to create a favorable r...
A novel laser-induced graphene-based strategy has been demonstrated for direct 'drawing' of highly precise, patterned electromagnetic metasurfaces. The metasurface exhibits excellent switching behavior across various frequency bands, enabling rapid switching between wave transmission and shielding.
Researchers have captured a new polar order in a hybrid crystal, enabling electric control of spin-orbit coupling and circular photogalvanic effect. The material exhibits three hallmarks: switchable net polarization, asynchronous switching, and field-driven polar-to-polar transition.
A study introduces an innovative monitoring platform leveraging aggregation-induced emission (AIE) technology to track complex dynamics across multiple scales. Real-time fluorescence monitoring resolves film formation stages at the molecular level, while super-resolution microscopy unveils detailed particle fusion dynamics.
Researchers have developed a new method to create smaller soft robots using 'bubble magic' that can navigate and operate within the body's narrow orifices. The soft robots, powered by fluid, have mirror-smooth skin and are ten times slimmer than previous versions.
Researchers unveil a paradigm shift in rechargeable Na-Cl2 battery systems by transforming conventional anode-protective additives into efficient cathode catalysts. The discovery reveals a hidden chemistry behind record-breaking performance and cycle life.
A team of scientists has developed a breakthrough floating droplet electricity generator that directly incorporates natural water into its structure, reducing material weight by about 80% and cost by about 50%. The device produces high peak output voltages comparable to conventional systems.
Engineers develop a self-forming protective layer to prevent dendrite growth and parasitic reactions, enabling unprecedented performance and resilience. The bi-directional regulation system maintains stability across wide temperatures, paving the way for practical grid-scale applications.
Researchers have uncovered a novel mechanism linking lactate metabolism to muscle Growth differentiation factor 15 (GDF15) release during mitochondrial stress, providing a potential therapeutic target for mitochondrial myopathy. Elevated lactate production and histone lactylation activate GDF15 gene expression.
Researchers develop new electrochromic MOF platform by mixing two materials at the molecular level, allowing multidirectional control of color change. This innovation enables future smart electronics with quick, reversible and energy-efficient color responses.
The POINT platform integrates multiple biological networks, advanced algorithms, and a comprehensive biomedical knowledge graph to analyze drug-disease interactions. It combines node degree with deep learning methods to improve target prediction accuracy.
Type 2 diabetes has become a global epidemic with unequal burden, driven by ageing, dietary shifts, sedentary behaviour, and early-life exposures. The true cost of diabetes includes significant healthcare and economic burdens, but prevention remains the weakest link.
Scientists have developed a novel 'double molecular bridge' strategy to enhance charge transport in perovskite solar cells, leading to improved efficiency and reduced nonradiative losses. This breakthrough confirms the importance of interfaces in perovskite photovoltaics and opens up new avenues for interface engineering.
Researchers use ultraviolet light to create angstrom-sized channels in polymer membranes, allowing for precise separation of ions and small molecules. The technique enables sieving of monovalent ions from multivalent ions, with adjustable channel sizes.