Researchers identified serotonin as the chemical responsible for inhibiting milk production and secretion in human mammary glands. The finding could aid development of therapeutics to increase milk production, aiding efforts to alleviate milk shortages worldwide.
A new technique developed by UC radiologists uses multi-detector computed tomography (CT) scanners to capture images of chest veins. This approach allows for better diagnosis of venous diseases by compensating for the extra time it takes contrast solution to reach the veins.
Researchers aim to improve diagnosis and treatment of neurologic emergencies with rapid, reliable information. The Point-of-Care Center will focus on developing technologies for fast and accurate diagnosis at the bedside or in the operating room.
Researchers found that 96% of Nigerian consumer paints contained higher than recommended lead levels, with bright-colored paints posing the greatest risk. The study highlights the need for international regulations to supplement local efforts and eliminate lead from paint globally.
A brain system known to regulate food intake also controls fat storage and metabolism in the body completely independently of food consumption. The melanocortin system may be used to develop new medications to treat human obesity.
Professor Andrew Steckl's innovative approach incorporates DNA from salmon sperm into light-emitting diodes, enhancing performance while reducing environmental impact. The technique involves trapping electrons longer, resulting in brighter colors and improved light efficiency.
Scientists have developed a new 'knock-out' gene model that provides molecular clues to breast cancer, focusing on the role of estrogen receptors in mammary gland development. The study suggests that estrogen expression is essential for normal duct development during puberty, pregnancy and lactation.
Researchers develop wearable sensors that can detect and measure particles in the air, improving the ability to identify environmental exposures. The technology uses microfluidics and geographic information system technology to track specific exposures.
A common molecular pathway called retinoblastoma (RB) tumor suppressor could help predict which lung cancer patients will benefit from chemotherapy drugs. Researchers found that turning off the RB pathway resulted in an altered response to chemotherapy agents and more cancer cell death.
Researchers from the University of Cincinnati and Louisville found that facial transplant outcomes differ significantly from previous data on kidney and hand transplants. They suggest a more optimistic view of face transplantation, with lower rates of acute and chronic rejection.
Assistant Professor Michael Fry and student Andrew Lundberg developed a model to help fantasy football players make informed decisions during drafts. The team's approach uses a combination of player value, available players, and team need to identify the best players to select.
A study published in The FASEB Journal has identified specific physiological properties that regulate melanocyte function, offering hope for new treatments of pigmentation disorders. Keratinocytes are found to influence pigment production and help regulate skin coloration.
Researchers at the University of Cincinnati have designed an AI software program that can recognize jokes, marking a significant advancement in computer capabilities. The bot uses phonological similarity and wordplay to identify humor, but is still limited by its current knowledge base and formal communication systems.
A new study examines how Latino immigrants identify themselves racially in the US, finding a significant share identifies as Latino rather than white. Increasing exposure to American culture leads to a shift towards Spanish racial self-identification, contrasting with earlier European immigrant groups.
New research from the University of Cincinnati finds that nearly half of workers wish they worked fewer hours, and 49% prefer changing their schedule. The study also reveals that many workers are willing to give up pay for greater flexibility, but face barriers in the workplace.
Research conducted by UC Sociology Professor David Maume found that women are more likely to leave their jobs to attend to their children, while men prioritize work. The study suggests that traditional gender roles persist despite changing attitudes on family responsibilities.
A recent study reveals that minority families moving to new neighborhoods experience equal or better economic gains compared to whites, but white children remain in wealthier areas. The research also finds that staying in one's neighborhood leads to greater economic improvements for white families than non-migrant minorities.
Researchers found that suppressing the endothelial nitric oxide synthase (NOS-3) gene led to intracranial aneurysm formation in 33% of study subjects. The study suggests that NOS-3 plays a crucial role in vascular remodeling and may be a marker for increased risk of brain aneurysms.
Researchers at the University of Cincinnati will use functional MRI and MRS to study brain chemistry in response to different treatments. The goal is to better understand the disease, identify early warning signs, and personalize treatment plans.
The University of Cincinnati has received a $1.7 million grant from the National Institutes of Health to research molecular treatment of brain injury. Dr. Kenneth Strauss will study eicosanoids, which can protect healthy brain cells from further damage.
A study led by University of Cincinnati scientists has found that the RON receptor is overexpressed in pancreatic cancer cells, suggesting a link between the receptor and disease development. The researchers believe blocking the receptor's signaling pathways could lead to new therapies for this deadly disease.
Researchers at the University of Cincinnati have successfully integrated minimally invasive lung surgery into their training programs with a standardized plan, increasing procedures by 57% over four years. The minimally invasive lobectomy results in faster recovery time and less pain for patients.
University of Cincinnati researchers have created a unique online system to reduce medical errors and improve patient care in local hospital emergency departments. The initiative, called the Committee for Procedural Quality and Evidence-Based Practice (CPQE), covers numerous conditions from triage and diagnosis to treatment and discharge.
Researchers identified a surprising trend in their study of 53 Ohio children with intracranial arterial aneurysms: most cases occurred spontaneously, without trauma or infection. This finding suggests unknown genetic factors, environmental exposures, or interaction between the two may predispose certain children to aneurysm development.
Researchers have developed a dual-imaging technique that combines functional magnetic resonance imaging (MRI) and diffusion tensor tractography to outline important areas of brain function and their connections prior to surgery. This approach has been used in 20 cases at Cincinnati's University Hospital and shows promising results in o...
A new research center at the University of Cincinnati is uniting biomedical competitors to fund medical technology development. The Minimally Invasive Medical Technologies Center (MIMTeC) will focus on translational research that enables U.S. companies to bring next-generation minimally invasive technologies to market.
A study by University of Cincinnati researcher David Hom found that treating skin wounds with a concentrated topical gel of the patient's own blood platelets resulted in faster healing. The gel showed a statistically significant increased wound closure compared to antibiotic ointment, with some sites closing up to two days earlier.
UC scientists developed a model to combine current clot-busting medication with below-normal body temperatures to improve ischemic stroke patient treatment. The study found that tPA, an enzyme used in standard stroke treatment, is less effective at lower temperatures, but a higher dosage may be needed.
Researchers at University of Cincinnati have found that bone marrow stem cells can differentiate into keratocan-producing cells, potentially treating abnormal corneal cell growth. The study showed that injected stem cells altered the shape and healed abnormal corneas in animal models within a week
Researchers from University of Cincinnati have found a connection between flexibility and ion motion in solid electrolytes. The team, led by Punit Boolchand, synthesized materials that exhibit three elastic domains and demonstrated increased electrical conductivity in the flexible phase.
Researchers explore how religious leaders and congregations respond to HIV/AIDS, with a focus on the impact on black church communities. The study aims to identify existing support groups and reveal how social networks can increase self-worth and prolong lives.
A recent study by University of Cincinnati researchers suggests that early exposure to indoor fungal components can help build stronger immune systems and protect against future allergies. Infants exposed to high levels of fungal glucans were nearly three times less likely to wheeze compared to those with low levels.
Researchers at University of Cincinnati developed a novel composite catalyst and optimal synthesis conditions to grow extremely long aligned carbon nanotube arrays. The longest array reached 18 mm in length, opening doors to potential applications in nanomedicine, aerospace and electronics.
Researchers found that succimer chelation therapy improved postural balance by 6 percent and moving tasks by 19 percent in lead-exposed children. The therapy was effective in reducing lead levels in the blood but also showed benefits on neuromotor abilities.
A combined imaging approach that combines standard MRI scans with specialized contrast-enhanced techniques may provide more effective diagnoses in patients with difficult-to-detect blood clots in veins of the brain. This approach could lead to better understanding of the disease process and potentially alter treatment regimens.
The number of certified geriatricians in the US is declining, with only 67% of fellowship positions filled in 2005-06. Geriatric students are deterred by lower salaries and smaller work schedules.
Research on microfluidics widens the possibilities for electronic devices through electrowetting-based liquid-state-field-effect transistors (LiquiFETs). These devices can directly convert charge-related information from liquids into electronic signals, enabling real-time evaluation and adjustment of drug delivery.
A new medical device developed by University of Cincinnati researchers could identify olfactory disorders that may be an early warning sign for Alzheimer’s disease, Parkinson’s disease, and other conditions. The Sniff Magnitude Test uses a simple observation to measure sniff size when detecting odors.
Hispanics are the fastest growing minority population in the US, with socioeconomic and lifestyle differences contributing to preventable cancer deaths. A global initiative on cancer education and early detection could reduce mortality rates among this population.
A team at the University of Cincinnati discovered a new way to combat antibiotic-resistant bacteria by substituting gallium for iron, preventing bacterial growth and biofilm formation. This method shows promise in treating lung infections, particularly in cystic fibrosis patients.
Researchers have developed a new diesel exposure model that improves accuracy in assessing air pollution risks, particularly for children. The model takes into account complex factors such as elevation and traffic volume to create 'buffers' around specific sample sites.
The Southwest Ohio STEM Secondary Teacher Academy will provide an intensive three-week summer experience, internships, and mentoring for 50 high school students. The program aims to recruit and prepare mathematics and science teachers from underrepresented groups to increase diversity in the teaching profession.
Researchers at the University of Cincinnati have created genetically modified skin cells that produce higher levels of human beta defensin 4 (HBD4), which killed more bacteria than normal skin cells. These cells may help combat infections in burn patients and reduce dependence on topical antibiotics.
Researchers discovered a new biomarker that predicts which tumors will resist anti-estrogen therapy, potentially improving treatment outcomes for breast cancer patients. The study found that disrupted retinoblastoma tumor suppressor pathway can lead to resistance to these therapies.
A University of Cincinnati-led study aims to identify specific genes associated with metabolic syndrome. Researchers will collect data from a genetically isolated population in Croatia to understand the complex relationship between genetics and lifestyle choices that contribute to the condition.
A study by the University of Cincinnati has found that infants living in homes with high levels of endotoxins and multiple dogs were more than two times less likely to wheeze. The researchers suggest that pet ownership may offer a protective effect against development of lower respiratory symptoms in young children.
Researchers have identified eosinophils as a major contributor to asthma symptoms, finding that they play a crucial role in mucous production and airway obstruction. The study suggests that targeting eosinophils could lead to the development of new treatments for asthma, which affects an estimated 17 million people in the US.
Researchers at the University of Cincinnati found that firefighters are twice as likely to develop testicular cancer and have higher rates of non-Hodgkin's lymphoma and prostate cancer. The study analyzed data from 110,000 firefighters and confirmed previous findings on multiple myeloma risk.
Researchers aim to create a topical cream that increases skin pigmentation and repairs DNA damage caused by UV radiation, reducing skin cancer risk. The project builds on previous findings that alpha-MSH can reverse the effects of UV radiation on skin cells.
Researchers at the University of Cincinnati found that MDMA can increase the survival of dopamine cells during fetal development. This may lead to better therapies for neurological diseases like Parkinson's. The study suggests that preventing dopamine cell death is key to finding lasting treatments.