A study by University of Cincinnati researchers found that high-fat diets can cause inflammation in fat tissue surrounding blood vessels, potentially leading to cardiovascular disease. The study suggests a direct link between poor dietary habits and inflammation of blood vessels, independent of weight gain or cholesterol levels.
Researchers at University of Cincinnati discovered that estrogen receptors are present in medulloblastoma, the most common type of pediatric brain tumor. This finding suggests that anti-estrogen drug treatments may be beneficial in limiting tumor progression and improving patient outcomes.
A study of umbilical cord blood found evidence of a biomarker associated with prenatal exposure to polycyclic aromatic hydrocarbons, potentially leading to pollution-related asthma. Researchers discovered epigenetic alterations in the ACSL3 gene linked to maternal PAH exposure.
A new study from the University of Cincinnati finds that cigarette smoke can activate specific immune system receptors, leading to worsening of chronic obstructive pulmonary disorder (COPD) symptoms. The research identified a key cellular receptor, NKG2D, involved in this process.
Researchers at the University of Cincinnati are developing new imaging technologies to help accurately pinpoint deep-brain stimulation electrodes in patients with Parkinson's disease. The study aims to reduce complications and improve patient outcomes by utilizing advanced MRI sequences and diffusion tensor imaging.
New analysis by University of Cincinnati researchers found that genetic testing to guide initial dosing of warfarin may not be worth the costs for typical patients. However, it could be beneficial for those at high risk of major bleeding. The study suggests that testing should be done in-house and at lower cost without delays.
Researchers at the University of Cincinnati have identified a potential biomarker for predicting colon cancer risk and progression. They found genetic hotspots that regulate gene expression, which could be used to identify individuals at higher risk of developing aggressive colon cancer.
Researchers found that adolescents with inflammatory bowel disease (IBD) who have a stronger sense of spirituality tend to experience fewer depressive symptoms and better emotional well-being. In contrast, patients with IBD are at risk for numerous psychosocial difficulties, including increased mental health problems and social stigma.
Researchers at the University of Cincinnati have identified a new tumor suppressor, protein kinase C-zeta, that may help develop targeted drug therapies to combat lung cancer. The study found that PKC-zeta normally slows down Ras transformation and prevents tumor development, but its absence or inactivity accelerates cancer growth.
Researchers discovered that bortezomib is effective in treating rejection episodes caused by antibodies targeting transplanted kidneys. The study found prompt rejection reversal, prolonged reductions in antibody levels, and improved organ function with suppression of recurrent rejection for at least five months.
A collaborative effort between Procter & Gamble and the University of Cincinnati has developed a center of expertise in computer simulation. The UC Simulation Center provides P&G with virtual modeling and simulation capacity, saving costs, time, and engineering resources.
A new spinal deformity classification system has been developed to define the range of normalcy for spine alignment. The system, published in Neurosurgery, uses a systematic approach to define neutral upright spinal alignment across different age groups.
A team of University of Cincinnati researchers has found that zinc plays a crucial role in the formation of biofilms that cause hospital-acquired infections. By removing zinc from bacterial cells, they were able to prevent biofilm formation and growth, offering new hope for preventing these infections.
A study published in Neurosurgery found that routine testing with cerebral angiography following endovascular treatment of brain aneurysms carries a very low risk of complication. The test was shown to have a complication rate of 0.43 percent, with only one major and permanent complication occurring.
The University of Cincinnati's CERHAS project is rebuilding the lost structures and interiors of the Shaker community using virtual reconstruction technology. The goal is to preserve the unique architectural legacy of the Shakers, which has had a lasting impact on American architecture and design.
Researchers at University of Cincinnati discovered a gene that helps control stomach acid production, which could lead to new therapies for overproduction. The study found that eliminating the Slc26a9 transporter gene stops acid secretion in the stomach.
Researchers at the University of Cincinnati identified a second, potentially more significant source of radon exposure at a former Ohio uranium-processing plant. Six silos filled with uranium ore in the production area resulted in relatively high levels of radon exposure to 12% of workers, while over half were exposed to low levels.
A new study by researchers at the University of Cincinnati shows that eliminating steroid therapy as early as seven days following a transplant surgery maintains kidney function. The study found reduction in steroid-related complications, even when prednisone was given in very low doses.
Research finds that marijuana use during adolescence is associated with poorer performance on thinking tasks, including slower psychomotor speed and poorer complex attention, verbal memory, and planning ability. Chronic heavy use is linked to abnormal brain activation and impaired cognitive functioning even after a month of abstinence.
A University of Cincinnati study finds that bisphenol A (BPA) induces proteins protecting cancer cells from chemotherapy's toxic effects. Researchers suggest BPA may be a contributing factor to chemotherapy resistance in cancer patients.
Researchers aim to determine ideal flight times and altitudes to minimize health complications for wounded soldiers. The study will investigate the link between inflammatory changes, injury type, and flight timing.
A new study from the University of Cincinnati found that Bisphenol A (BPA) suppresses a key hormone, adiponectin, which regulates insulin sensitivity and puts people at risk for metabolic syndrome. The study used fresh human fat tissues and found that BPA exposure resulted in suppression of this hormone.
Researchers at the University of Cincinnati have found that deep brain stimulation can halt the progression of dopamine-cell loss in animal models. The study suggests that stimulating neurons with electrodes boosts the amount of BDNF, a protein that promotes neuronal growth.
A team of University of Cincinnati researchers is studying the relationship between depression and Parkinson's disease to gain insight into possible treatments. In pilot models, they found that stress-induced depression exacerbates problems with movement and causes brain cells to die faster.
The University of Cincinnati's Economics Center for Education & Research has released a report grading the HDR Streetcar Feasibility Study, finding that it is sound and economically worthwhile. The proposed four-mile streetcar system could bring in $315.8 million in net economic payoff over 35 years.
Researchers at University of Cincinnati are studying variations of rare lung disease Lymphangioleiomyomatosis (LAM) to better understand its manifestations and develop more effective treatments. The study will compare patients with and without pulmonary hypertension to identify key differences in symptoms.
A recent study found that over 30% of American public schools are within 400 meters of major highways, putting children at risk for respiratory diseases. The research suggests that proximity to highways and environmental pollutants can leave school-age children more susceptible to asthma and other chronic respiratory problems.
Research suggests that obese adolescents who experience peer victimization are more likely to struggle with depression and negative feelings about their physical appearance. Non-obese adolescents who face peer victimization also report decreased self-esteem and increased negative body image over time.
Carl Brett, a key figure in UC's paleontology program, has been awarded the second-ever Digby McLaren Medal for his significant international contributions to stratigraphy. The medal celebrates Canadian paleontologist Digby Johns McLaren, who was recognized for his impact theory and advocacy.
Research reveals that children raised by authoritarian parents are more prone to act out bullying behavior, while those from nurturing families are less likely to bully. The study also found that middle-income families are less likely to produce bullies than high- or low-income families.
A University of Cincinnati study found that residents who spent more time in outpatient settings delivered a higher quality of care and had greater satisfaction in their duties. The new system, implemented to reduce conflict between inpatient and outpatient care, provided hands-on learning and enhanced patient satisfaction.
University of Cincinnati geology researcher Tom Lowell discusses the latest research on the Younger Dryas event, a significant climate change event that occurred around 12,900 years ago. Lowell's team has found evidence of discrepancies in dating techniques used to study the event, which could have implications for understanding global...
A recent study suggests that excessive weight-bearing activities in children can affect the mechanical properties of developing bones, leading to a higher risk of degenerative skeletal disorders later in life. Researchers found that young boys who participated in regular farming activities had significantly lower bone-damping ability c...
A new review from the University of Cincinnati found that workplace-based weight loss programs are moderately effective at promoting weight loss among participating employees. The studies showed that face-to-face contact and high-intensity interventions were more effective than low-intensity programs in achieving significant weight loss.
Researchers at the University of Cincinnati have identified the role of transcription factors in controlling cell death in the heart, paving the way for gene regulatory therapy. They have successfully developed non-viral delivery mechanisms to transfer DNA and repress activation of specific transcription factors.
A new study by UC researchers suggests that cases of Amyotrophic Lateral Sclerosis (ALS) among soldiers who served in the first Persian Gulf War were caused by specific events, with a declining risk after 1996.
Research from the University of Cincinnati reveals a direct link between prenatal and early-childhood lead exposure and higher rates of criminal arrest in adulthood. Individuals with elevated blood-lead levels before birth and during early childhood had higher rates of arrests, especially for violent crimes.
Researchers confirm ancient sunflower domestication in Mexico dating back 4,000 years, contrary to previously believed eastern North American origin. This discovery highlights the importance of sunflower as a major oil seed crop and its potential for modern crop-breeding purposes.
Workers exposed to low levels of an asbestos-like mineral from Montana vermiculite are at increased risk for lung disease today. A 25-year follow-up study found that even low cumulative exposure can cause changes in the lining around the lungs.
A University of Cincinnati study found that new coiling devices are no more effective than traditional bare platinum coils in preventing brain aneurysm recurrence. The study analyzed 100 patients and found a higher rate of repeated treatments with the newer, more expensive coils.
A 2004 survey of 1,000 Iraqi adolescents found that those exposed to the Iraq War reported higher self-esteem levels compared to Palestinian youth. The study suggests that indirect threats to their social identities may contribute to this phenomenon.
Researchers found that boiling water increases BPA release from polycarbonate bottles, with rates increasing 15-55 times faster than at lower temperatures. The study's findings suggest that cumulative environmental exposures may harm human health.
A study published in the Journal of Neurosurgery found that simultaneous implantation of radioactive seeds and chemotherapy wafers following surgery improved patient survival rates for recurrent glioblastoma multiforme (GBM) patients. The median survival was 69 weeks, with nearly a quarter of patients surviving two years.
Researchers at the University of Cincinnati discovered that increased numbers of neutrophil cells in the lungs of IPF patients are associated with a 30% increased risk of mortality. This finding may lead to more accurate diagnoses and improved treatment options for those affected by idiopathic pulmonary fibrosis.
A University of Cincinnati researcher, Dionysios Dionysiou, received a $698,689 EPA grant to investigate processes used to purify drinking water and remove cyanobacterial toxins. The research aims to develop cost-efficient technologies to treat water contaminated by such toxins.
Researchers found that brief periods of blocked blood flow activate a protective molecular pathway in the heart, protecting it from damage caused by restored blood flow. The study suggests that these 'mini stress tests' may help precondition and protect the heart from future attacks.
A pilot program at the University of Cincinnati has shown promising results in curbing alcohol abuse among college students who turn to drinking to cope with social anxiety. The program uses motivational interviewing and behavioral therapy to help students manage their anxiety and reduce hazardous drinking behaviors.
Researchers have identified a molecule, osteopontin-c, that appears more accurate than existing biomarkers in predicting which breast cancers will develop into advanced forms. The discovery could one day influence therapy decisions and prevent patients from undergoing aggressive treatments.
Researchers at the University of Cincinnati have discovered a new molecular target that may help develop drugs to reduce fat transport in adipocytes and prevent obesity. Knocking out a specific cell receptor called LRP1 has been shown to decrease fat storage and weight gain in genetically altered mice.
Researcher Heidi Kloos investigates why young children are stumped by science, particularly the concept of density. Her findings suggest that alternative teaching approaches can help children navigate these waters more smoothly.