Cardiac researchers at the University of Cincinnati found a new cellular pathway that could help develop therapeutic treatments for obesity-related disorders, including diabetes and heart disease. The study identified histone deacetylase 9 (HDAC9) as a potential target for intervention.
Researchers at the University of Cincinnati found a link between fat around the outside of arteries and the development of cardiovascular disease, particularly in individuals with diabetes. The study suggests that this fat tissue, known as perivascular adipose tissue, can lead to inflammation and unstable blood vessels, increasing the ...
Researchers at the University of Cincinnati have identified a protein called HAX-1 that protects cardiac cells and muscle from damage during ischemia-reperfusion injury. The study found that HAX-1 levels were reduced in hearts after heart attack, but overproduction improved contractile performance and decreased cell death.
Researchers at the University of Cincinnati have developed a stem cell-infused patch that promotes cell migration to damaged cardiac tissue following a heart attack, resulting in improved function. The patch combines cardiomyocytes, endothelial cells, and embryonic fibroblasts to enhance regeneration of heart tissues.
US science educator Piyush Swami shares his expertise on US preparation of science teachers and the emphasis on inquiry skills, critical thinking, and problem-solving. He also looks forward to learning from Chinese colleagues about their approaches to science education and teacher preparation.
University of Cincinnati researchers found that pleasurable activities like tasty foods and sex can reduce stress by weakening anxiety responses in the brain. The findings suggest a long-term benefit and could potentially provide strategies for intervening in metabolic disorders.
New studies from researchers at the University of Cincinnati show that certain measurement tools for assessing non-clinical work intensity can also be used to determine physician work intensity in clinical settings. This could lead to improved health care delivery, increased efficiency, and higher quality of care.
Clement Loo, a University of Cincinnati doctoral student, presented his research on invasive species and the Shifting Balance Theory at an international conference. His paper argues that this theory is more nuanced than traditional Fisherian gradual mass selection in understanding the evolution of invasiveness.
Chronic kidney disease patients who don't adhere to high blood pressure medications are more likely to have sub-optimal blood pressure control. Improving medication adherence can greatly improve outcomes for these patients.
Researchers at UC discover that rabbit food can effectively reduce estrogen levels in wastewater, with a potential impact on the environment and wildlife. The study found that the rabbit food reduced estrogen hormone levels by more than 80%, making it a promising alternative for treatment.
The University of Cincinnati presented multiple papers at the Geological Society of America annual meeting, focusing on Permian extinction understanding, oceanic oxygen depletion, nitrogen cycles, ancient plant water use, and fossil classification. Research by UC geologists shed light on climate change mechanisms.
A team of researchers led by Thomas Algeo from the University of Cincinnati analyzed chemical evidence from rocks formed during the Permian-Triassic extinction event, which wiped out 90% of all living species. The study suggests that massive volcanic eruptions in Siberia and global climate change contributed to the catastrophic event.
The new electrofluidics design combines the best features of both slow and fast electronic devices, requiring low-power and displaying bright images at high speed. This technology is manufacturable using existing equipment, making it a game-changer for environmentally friendly electronics.
Researchers found that over 70% of particulates released during fires are ultrafine and can be inhaled into the lungs. Firefighters are at a higher risk of heart disease due to exposure to these harmful particles, particularly those with low physical fitness or health.
The larvae of the sunburst diving beetle have been found to possess bifocal lenses in four of their twelve eyes, allowing for efficient switching between close-up and distance vision. This discovery has implications for biomedical engineering and imaging technology, with potential applications for humans.
A decade-long trial confirms that early corticosteroids withdrawal improves graft survival rates, patient survival rates, and reduces cardiovascular events in transplant patients. The study shows a significant reduction in non-PTLD cancer risk among ECSWD patients.
Researchers at UC's College of Education will develop an interactive software suite called iFIG to enhance student learning in science. The system features three components: digital handbook, digital notebook, and assessment system, designed around Universal Design for Learning framework.
A study by University of Cincinnati professor David Maume found that men who worked late shifts believed it negatively impacted their marriages, whereas most women saw rotating work schedules as a strain on their marriages. Women reported greater difficulty in caring for and nurturing family members due to their schedules.
Research by Elizabeth Sweeney examines how biomedical tests diagnose and define pain, leading to emotional suffering for patients with unexplained conditions. The study analyzes over 20 articles from the journal Pain®, highlighting challenges in diagnosing chronic pain.
Researchers found that white population shifted from central city to outer ring suburbs, but minority representation was relatively flat across suburban rings. The study suggests a radial pattern of minority movement out from the central city rather than filling in inner suburbs.
A pilot study found that reducing musculoskeletal pain by 20-30% is a key motivator for weight loss. The study, published in the journal Work, suggests that immediate health benefits can inspire overweight individuals to shed extra weight and commit to keeping it off.
Research from University of Cincinnati finds that sales turnover is the only uniform corporate indicator predicting a firm's bankruptcy in three major economies. The study also reveals that different financial factors are correlated with bankruptcy in each country, mainly due to varying financial and business structures.
A new technology initiative aims to measure the effectiveness of UC's STEMM education efforts while reducing paper usage. The project uses 35 iPads to collect survey results and performance evaluations, cutting down on scanning time and storage space.
New research reveals that cellular changes in fat tissue, rather than the immune system, contribute to glucose intolerance and type 2 diabetes. The study found that a specific gene, protein kinase C-zeta, promotes inflammation in fat cells, leading to insulin resistance.
Researchers have developed a diagnostic blood test that can identify lymphangioleiomyomatosis (LAM), a rare but serious lung disease affecting women. The test analyzes serum VEGF-D levels, showing high accuracy in diagnosing LAM, and may help screen for the disease in women with Tuberous Sclerosis Complex.
Research by UC Health cardiologists found that while worsening kidney function is common among heart failure patients, those with transient worsening kidney function have better outcomes than those with persistent kidney failure. The study of 467 patients also showed a significant difference in mortality rates between the two groups.
Researchers at UC are developing carbohyrate-based diagnostics for influenza virus using a $2.3 million NIH grant. The team aims to create rapid, user-friendly tests for early detection and accurate typing of the flu strain.
Researchers at the University of Cincinnati propose that the structure of vodkas is responsible for variation in taste. The team found that different vodkas have varying levels of a cage-like hydrogen-bonded structure, which could affect the way they are perceived by the palate.
Researchers at the University of Cincinnati found that ghrelin, a hunger-signaling hormone, regulates cholesterol levels in the brain. Increased ghrelin levels caused mice to develop higher blood-circulating cholesterol, suggesting a potential 'remote control' mechanism.
The University of Cincinnati's School of Design contributed 22 new signage symbols to the 'Signs that Work' project, which aims to create a universal system for hospital signage. The new symbols will be integrated into a total of 50 symbols and tested at four national hospital sites.
A team of researchers led by Malak Kotb has found that as dominant members of a bacterial community surrender to host immune defenses, they are replaced by a hyperaggressive, mutant minority population that thrives and takes over. This study provides new insights into the dynamics of bacterial evolution in live species.
Researchers found post-transplant patients off steroids have similar graft-function outcomes as those on steroids but with fewer cardiovascular events. This study contributes to a reduction in patient exposure to corticosteroids during post-transplantation treatment, improving graft survival rates and reducing early mortality.
Researchers discovered that metformin disables the mTOR complex through RAG GTPase, rather than activating TSC proteins via AMPK. This finding raises the possibility of using metformin more widely to treat cancer and diseases linked to TSC deficiency.
A recent study has linked leptin action in the brain to sepsis survival. Researchers found that leptin mediates actions in the central nervous system, improving the host response to a standard model of sepsis.
A new research paper concludes that deterrence can no longer be the primary national cybersecurity strategy due to the unique characteristics of cyberspace. Experts propose a three-tiered approach to guide US strategy in responding to cyber threats, emphasizing war-fighting and offense-defense frameworks to contain damage and reduce harm.
Researchers have developed a minimally invasive endoscopic procedure that can safely remove large brain tumors from an area at the bottom of the skull, near the sinus cavities. The study found that this approach resulted in complete tumor removal in 96% of patients and could be a game-changer for patients with pituitary macroadenomas.
William Vanooij, a renowned engineering professor and entrepreneur, has earned the first Ohio Patent Award for his work on silane surface treatments that enhance corrosion protection of metals. His patented technology has led to the development of special radial tires with improved performance.
UC engineering researchers have created a paradigm shift in microfluidics by developing a lab-on-a-chip with programmable microfluidic systems. This innovation enables the reconfiguration of microchannel structure as needed for performing various biomedical assays, such as DNA analysis and immunoassays.
A new pilot study led by UC and VA researchers is evaluating the functional significance of blockages in cardiac blood vessels. Using a formula derived from fluid mechanics principles, they aim to provide more accurate assessments of vessel blockages.
Researchers at the University of Cincinnati have created a semi-tropical frog-inspired foam that converts solar energy into sugars. The foam, which uses plant, bacterial, and fungal enzymes, can produce fuels like ethanol without diverting energy to other functions.
A genetic variant identified by researchers at the University of Cincinnati significantly increases lung cancer risk for individuals who smoke lightly, even if they are not heavy smokers. Family members with this genetic variant should be monitored for early detection, regardless of their smoking habits.
Researchers found that CT scan screening for lymphangioleiomyomatosis (LAM) is cost-effective among non-smoking women aged 25-54 with a collapsed lung. The study suggests that early diagnosis can improve quality of life and treatment outcomes for patients.
The University of Cincinnati researchers will investigate ways ILD appears in patient groups with autoimmune diseases and develop more efficient diagnosis and treatment methods. The study aims to identify specific biomarkers and medical records characteristics that predict the best treatment outcomes for ILD patients.
A study by researchers at the University of Cincinnati Neuroscience Institute supports the use of Keppra as an alternative to Dilantin for preventing seizures in patients after a brain injury. Patients treated with Keppra had fewer side effects and better long-term outcomes compared to those receiving Dilantin.
Researchers at University of Cincinnati identify p62 and ERK as a critical protein duo involved in adipogenesis. The study shows how the interplay between these proteins leads to uncontrolled ERK activity, highlighting ERK as a promising target for obesity therapies.
A study by University of Cincinnati researchers found that proapoptotic peptide treatment reduced food intake and fat loss in obese mice and rats, without affecting energy expenditure. The findings suggest a novel system informing brain activity about fat tissue size, influencing appetite and weight regulation.
UC researchers argue that citizen awareness and participation are essential for a robust cybersecurity strategy. They recommend a three-pronged approach: coordination between government agencies and business interests, engagement with the public about their role in cybersecurity, and education on safe computer practices.
Researchers at the University of Cincinnati are receiving a $3.75 million grant to study tendon development and create better repairs after injury using adult stem cells. The goal is to introduce signals that mimic normal tendon development during repair, leading to more effective soft tissue repairs.
Researchers at UC's College of Design, Architecture, Art, and Planning have developed an online toolkit to help educators assist children with dyslexia. The 'Reading by Design' project uses a multisensory approach to increase reading and retention abilities for children aged 9-11 with dyslexia.
UC researcher Michal Polak confirms one of Darwin's theories by showing that the spines on Drosophila bipectinata males assist them in copulation. The study found that removing these spines resulted in drastic reductions in ability to copulate and compete for mates.