Researchers have designed a new software called QuasiFlow to analyze the genetic variability of SARS-CoV-2 and identify its weak points. The goal is to develop a combination antiviral therapy that combines lethal mutagenesis with inhibitors to prevent the virus from evading the innate immune response.
Researchers have identified a rare genetic bone disorder by using precision medicine strategies, uncovering mutations in the LAMA5 gene that cause extreme bone fragility and skeletal deformity. The study also revealed a new signaling pathway governing skeleton formation, which could be used for common bone conditions.
Researchers at the University of Malaga have developed a method to generate human oligodendrocytes from pluripotent stem cells, crucial for supporting neural activity. This breakthrough enables the creation of OLs in just three weeks, opening up new possibilities for treating neurodegenerative diseases such as multiple sclerosis and ALS.
A study published in Circulation journal reveals that a specific population of cardiac fibroblasts, called Reparative Cardiac Fibroblasts (RCF), play a crucial role in repairing damaged heart tissue after a myocardial infarction. The RCF cells produce a protein called CTHRC1, which is essential for the healing process.
Researchers discovered resistance to tumor inhibitors arises from gradual adaptation to selective pressures, providing opportunity for effective therapies. The study advances in evolution of resistance and offers evolutionary-informed therapies for future treatments.
Researchers at University of Malaga's BacBio laboratory have identified a new role for an amyloid protein, improving biological control methods in sustainable agriculture. The study reveals the dual functionality of the protein, which helps bacterial cells attach to plant surfaces, combat pathogens and improve fitness.
Researchers at the University of Malaga have developed a new global prediction model for sudden stops of capital flows using decision trees. The model identifies key economic factors that predict this event in both emerging and developed countries, allowing for early detection and prevention.
A team of researchers has identified new biomarkers for the diagnosis and prognosis of lung cancer by analyzing repetitive DNA regions. These markers show consistent expression in both healthy cells and cancerous tumors, with potential applications for more accurate diagnoses and treatments.
Researchers from UMA developed a method using deep learning to increase brain image quality and detection of pathologies with increased accuracy. This breakthrough technique enables specialists to identify brain-related disorders more accurately and definitionally, reducing the need for additional tests.
Researchers from the University of Malaga have developed a software to improve cognitive abilities in athletes, particularly soccer players. The study found that computerized training enhances their selective attention, enabling them to focus on specific stimuli and make creative decisions during games.
Researchers at the University of Malaga created a low-cost T-shirt that generates electricity from temperature differences between the human body and surroundings. The 'e-textile' prototype uses biodegradable materials such as tomato skin and carbon nanoparticles to produce electrical power.
Researchers at the University of Malaga found that social interaction can diminish interest in cocaine. The study used an animal model and showed that positive stimuli like social interaction with another animal reduced preference for the drug.
Researchers detected a significant correlation between kinesiophobia and chronic musculoskeletal pain, with increased fear of movement linked to longer pain durations. In contrast, whiplash patients showed less influence from kinesiophobia, suggesting other factors at play.
Researchers discovered a new function in the BAG4 protein, which regulates potassium transport and optimizes water use by plants. This finding is crucial for developing crops resistant to drought conditions.
A study published in Frontiers in Psychology found that children born by cesarean section had lower intellectual levels and cognitive development compared to those born vaginally. The research analyzed data from 160 twins and suggests that vaginal delivery may have benefits for psychological development.
A study by Professor Raquel Cantero of the University of Malaga has found a direct correlation between mobile phone use and thumb pain. The researcher predicts that changes in thumb use due to technology could lead to alterations in hand evolution.
Researchers at University of Malaga identify a fragment of the brain molecule Galanin as involved in anhedonia, a key symptom of depression. The study suggests potential new therapeutic strategies for treating depression and related addictions.
Researchers from the University of Malaga have found that combining 'Bacillus subtilis' and 'Pseudomonas' bacteria can improve plant growth and health. This study reveals that these bacteria can live in harmony, increasing their positive effects when used together.
A study by University of Malaga researchers reveals that DNA methylation levels in genes related to lipid metabolism and inflammation are altered in obese patients with a metabolic disease. This dysregulation may contribute to the development of obesity-related diseases such as diabetes, cardiovascular disease, and cancer.
The study shows that Wt1 gene deletion causes deterioration of the pancreas and activates stellate cells, which play a key role in pancreatic cancer progression. The results suggest Wt1 gene is necessary for normal pancreas maintenance and repair after damage.
Researchers developed a mechanized cane that measures patients' rehabilitation process, providing individualized information on their progress. The device is adaptable to users, low-cost, and has been downloaded by over 150 researchers worldwide.
Experts find that folate levels decrease in summer due to increased UV radiation, recommending higher intake of folate-rich foods during this period. Low folate levels are linked to various health conditions, including megaloblastic anemia and cardiovascular diseases.
Researchers at the University of Malaga have discovered that sulfur atoms can exhibit both donative and repulsive behavior, leading to the creation of more stable and functional organic diradicals. These findings have significant implications for various scientific fields, including chemistry and environmental science.