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University of Michigan


Green tea extract interferes with the formation of amyloid plaques in Alzheimer's disease

Researchers at the University of Michigan have discovered that green tea extract can prevent the misfolding of specific proteins in the brain, which is associated with Alzheimer's disease. The study found that a molecule in green tea, EGCG, prevented aggregate formation and broke down existing structures in proteins containing metals.

SourceUniversity of Michigan·JournalProceedings of the National Academy of Sciences·DateMar 5, 2013

Stay cool and live longer?

Researchers discovered a genetic program that promotes longevity in roundworms at cold temperatures and found it exists in humans. The study links calcium signaling to aging for the first time, suggesting exposure to cold air or stimulation of this genetic program may promote mammalian longevity.

SourceUniversity of Michigan·JournalCell·DateFeb 14, 2013

Empathy and age

A study of over 75,000 adults found that late middle-aged adults, particularly women, report higher levels of emotional reactivity and perspective-taking. This inverted U-shaped pattern suggests a potential link between age-related cognitive changes and empathy.

A material that most liquids won't wet

Researchers at University of Michigan developed a nanoscale coating that repels over 95% of liquids, including oils, alcohols, and toxic acids. The coating uses air pockets to reduce intermolecular forces, causing liquids to bounce off the surface.

SourceUniversity of Michigan·JournalJournal of the American Chemical Society·DateJan 16, 2013

Monkey business: What howler monkeys can tell us about the role of interbreeding in human evolution

A University of Michigan-led study found that individuals of mixed ancestry among hybrid howler monkeys are physically indistinguishable from pure individuals of each species. The findings suggest that the role of interbreeding in human evolution may have been underestimated due to limitations in the fossil record.

SourceUniversity of Michigan·JournalAmerican Journal of Physical Anthropology·DateDec 7, 2012

U-M study shows BPA exposure in fetal livers

Researchers at U-M found BPA in fetal liver tissue, with varying levels of exposure detected. The study suggests that fetuses may not be able to metabolize BPA as effectively as adults, highlighting the importance of understanding internal doses for health effects.

SourceUniversity of Michigan·JournalJournal of Biochemical and Molecular Toxicology·DateDec 3, 2012

Saving lives could start at shift change: A simple way to improve hospital handoff conversations

A study led by the University of Michigan found that doctors tend to spend excessive time on early cases and rush at the end of the list, leading to miscommunication and preventable medical errors. Researchers suggest prioritizing handoff conversations for the sickest patients first to improve patient care and reduce errors.

SourceUniversity of Michigan·JournalArchives of Internal Medicine·DateNov 12, 2012

Divorce costs thousands of women health insurance coverage

A University of Michigan study found that 115,000 women lose their private health insurance every year after divorce, leading to depression for more than two years. Women in moderate-income families face the greatest loss of insurance coverage, while full-time work and education can serve as buffers against losing health insurance.

SourceUniversity of Michigan·JournalJournal of Health and Social Behavior·DateNov 12, 2012

Target for obesity drugs comes into focus

Scientists at the University of Michigan have made a groundbreaking discovery in understanding how the hormone leptin regulates metabolism and body weight. By visualizing the interaction between leptin and its receptor, researchers may develop new drugs to overcome leptin resistance, a key factor in obesity.

SourceUniversity of Michigan·JournalMolecular Cell·DateOct 11, 2012

Popular antidepressant might prevent heart failure

Researchers at the University of Michigan discovered that paroxetine inhibits GRK2, a protein kinase involved in heart failure, improving myocardial contractility without affecting heart rate. The team hopes to optimize and develop these compounds into therapeutic leads for heart failure treatment.

SourceUniversity of Michigan·JournalACS Chemical Biology·DateOct 1, 2012