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University of Michigan


H.pylori bacteria and their human hosts

A mathematical model of H.pylori bacteria and their human hosts reveals the key role played by adherent bacteria in colonization, as well as the dynamic relationship between host response and bacterial persistence. The model sheds light on the complex interactions between the bacteria and human immune system.

SourceUniversity of Michigan·JournalProceedings of the National Academy of Sciences·DateJul 20, 1999

Heart failure deaths reduced by 30 percent

Researchers observed a substantial reduction in mortality for heart failure patients who received the Aldactone medication regimen, reducing deaths by 30 percent. The study found that aldosterone blockade played an important role in this reduction and opens the door to developing more effective treatment options.

SourceUniversity of Michigan·JournalNew England Journal of Medicine·DateJul 19, 1999

Inhaled drug useful in preventing flu

A new study by University of Michigan professor Dr. Arnold S. Monto found that zanamivir, an antiviral drug, is 67% effective in preventing laboratory-confirmed clinical influenza infection. The drug was also shown to be 84% effective in preventing laboratory-confirmed illnesses with fever.

SourceUniversity of Michigan·JournalJAMA·DateJul 6, 1999

Help for women's urinary tract infections

A new study published in the American Journal of Medicine finds that managed care insurance systems can standardize care, eliminate unnecessary tests, and minimize antibiotic resistance by implementing a single guideline for treating uncomplicated urinary tract infections. The study, which included over 3,800 women, showed that using a...

Treatment restores normal heart rhythm in patients

A new treatment approach has been developed to restore normal heart rhythms in patients with atrial fibrillation, a condition affecting over 2 million adults. Ibutilide fumarate injection prior to an electrical shock to the heart was successful in converting abnormal rhythms to normal in all study patients.

SourceUniversity of Michigan·JournalNew England Journal of Medicine·DateJun 17, 1999

Cardiac surgery patients at higher risk

A new study found that cardiac surgery patients with serum potassium levels below 3.5 mmol/L are twice as likely to experience arrhythmias and a doubled need for cardiopulmonary resuscitation. Investigators recommend screening and replenishing potassium on a case-by-case basis.

SourceUniversity of Michigan·JournalJAMA·DateJun 15, 1999

Folic Acid Lowers Risk Of Cardiovascular Disease

Researchers at the University of Michigan discovered that folic acid effectively lowers homocysteine levels in blood plasma, reducing the risk of heart attacks and strokes. The study found that folic acid supplementation can also benefit people with normal MTHFR enzymes by protecting them against heat-induced enzyme inactivation.

SourceUniversity of Michigan·JournalNature Structural & Molecular Biology·DateApr 1, 1999

UV Radiation Induces Vitamin A Deficiency In Skin

Researchers discovered that UV radiation blocks the ability of skin cells to recognize retinoic acid, a nutrient made from vitamin A. This triggers a cascade of biochemical changes, causing a functional vitamin A deficiency in human skin. Pretreating skin with retinoic acid before UV exposure can limit the damage.

SourceUniversity of Michigan·JournalNature Medicine·DateMar 30, 1999

Who Cares For You When You're Ill

A new study by Peter D. Jacobson examines the role of nurse practitioners (NPs) and physician assistants (PAs) in primary care, finding that their scope of practice and autonomy increase with larger managed care populations. While most physicians view NPs and PAs as peers, some express concerns about quality of care and referrals.

New U-M Analysis Of Brain At Work

Researchers found that verbal storage tasks activate left-hemisphere speech areas, while spatial storage tasks activate specific areas of the right cortex. The study provides strong evidence for a more precise understanding of how various regions of the frontal cortex are involved in specific mental activities.

SourceUniversity of Michigan·JournalScience·DateMar 11, 1999

A Little Volunteering Can Prolong Your Life

A University of Michigan study found that seniors who volunteer for less than an hour a week are more likely to live longer. The study analyzed data from 1,211 older adults and discovered that volunteering is directly associated with increased survival rates, rather than just being a result of better health.

Dental Care And Family Income

African Americans are less likely to visit the dentist for routine visits due to lack of money and dental insurance. The study found that 13% of African Americans had never visited a dentist, compared to 1% of whites.

SourceUniversity of Michigan·JournalJournal of Public Health Dentistry·DateMar 1, 1999

Growth Factor Contributes To Angiogenesis

A University of Michigan team discovered that vascular endothelial growth factor (VEGF) helps blood vessels survive and proliferate in the face of nutrient depletion. This mechanism is thought to support tumor growth, leading researchers to explore strategies for inhibiting VEGF to starve tumors.

SourceUniversity of Michigan·JournalAmerican Journal Of Pathology·DateFeb 2, 1999

Diabetes And Periodontal Disease Connection

People with diabetes are at increased risk of getting periodontal disease, which can lead to problems with blood sugar control and complications like vision problems and cardiovascular disease. Clinical studies show that people with severe periodontal disease are six times more likely to have poor glycemic control.

Improving End-Of-Life Care For Terminally Ill

The Palliative Care Project challenges the current model of medical care, which forces terminally ill patients to choose between continued medical treatment and hospice care. The new program integrates both services, allowing patients to receive cutting-edge medical therapy while also benefiting from palliative care.

Cold Dust In Hot Gas Of Ancient Galaxies

University of Michigan astronomers have detected the cool infrared signature of dust grains and silicates within superheated gas in the center of ancient elliptical galaxies. The discovery could represent the first direct observation of how mass lost by aging stars evolves in a hot, exotic environment.

Role Of Government Branches In Tobacco War

A new University of Michigan study investigates the impact of tobacco litigation on public health policy, concluding that courts are not well-suited for adopting policy changes. The authors argue that building a moral and political case is essential to achieve tobacco control goals through legislative and regulatory processes.

AIDS Researchers Form "Virtual Center"

Researchers from the University of Michigan, Northwestern University, University of Minnesota, and University of Wisconsin have formed a virtual center to facilitate collaboration. This innovation uses collaborative tools and technology to enable researchers to work together as if they were in the same location.

Diagnosing Depression In Primary Care

A new study suggests that depression is a fluid disease requiring tracking over time for accurate diagnosis and treatment. Researchers found that physicians more frequently detected depression when they knew their patients well, but struggled to distinguish it from minimal impairment.

SourceUniversity of Michigan·JournalArchives of Family Medicine·DateOct 6, 1998

Surrogate Mothers Feel Some Degree Of Disappointment

A University of Michigan study reveals that surrogate mothers express some degree of disappointment about their roles, with those who have satisfied relationships with adoptive parents experiencing better outcomes. The quality of the relationship post-birth significantly impacts long-term satisfaction and regret among surrogate mothers.

Anti-Microbial Agent Kills Influenza Virus

Researchers at the University of Michigan have discovered a new anti-microbial agent called BCTP that effectively kills the influenza A virus in cell cultures and laboratory mice. The study found that BCTP is non-toxic to skin and mucous membranes, making it a promising alternative to traditional vaccines.

Blacks' Environmental Concerns Equal/Exceed Whites'

A recent study by the University of Michigan found that Blacks' environmental concerns equal or exceed those of whites, with greater concern about local pollution and poorer environmental quality. The survey of 793 people identified significant differences in environmental attitudes between Black and white neighborhoods.

SourceUniversity of Michigan·JournalPublic Opinion Quarterly·DateAug 24, 1998

Remembering Your Medications: Older Are Wiser

A University of Michigan study found that busy individuals are more prone to medication errors, whereas older adults tend to exhibit better adherence rates. The researchers developed the 'Busy Life Style Questionnaire' to measure daily chaos and identified being too busy as the primary risk factor for mistakes.